propranolol has been researched along with Subarachnoid Hemorrhage in 20 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seven patients (4 with subarachnoid hemorrhage, 2 with intracerebral hemorrhage, and 1 with massive cerebral infarction) had acute arterial hypertension refractory to control by several antihypertensive drugs (hydralazine, sodium nitroprusside, alpha-methyldopa, and trimethaphan camsylate) used singly or in combination." | 5.26 | Catecholamine-associated refractory hypertension following acute intracranial hemorrhage: control with propranolol. ( Baldwin, CA; Feibel, JH; Joynt, RJ, 1981) |
| "Under double-blind randomized conditions the effects of early intervention with oral propranolol or a placebo were studied in 51 cases of subarachnoid hemorrhage." | 5.06 | Beta-blockers, plasma total creatine kinase and creatine kinase myocardial isoenzyme, and the prognosis of subarachnoid hemorrhage. ( Cruickshank, J; Neil-Dwyer, G; Stratton, C, 1986) |
| "The Study on the treatment of 50 cases of subarachnoid hemorrhage (by applying beta-receptor blocking drug propranolol) and the control group of 55 cases revealed that the mortalities of the therapeutic group and the control group were respectively 4% and 9." | 3.68 | [A random sample study of therapeutic effect of beta-receptor blocking agents in patients with subarachnoid hemorrhage]. ( Wang, ML, 1991) |
| "These arrhythmias have responded to sympathetic blocking agents, which may also have a protective effect on subendocardial tissue in this setting." | 1.27 | Subarachnoid hemorrhage and the heart. ( Marion, DW; Segal, R; Thompson, ME, 1986) |
| "Seven patients (4 with subarachnoid hemorrhage, 2 with intracerebral hemorrhage, and 1 with massive cerebral infarction) had acute arterial hypertension refractory to control by several antihypertensive drugs (hydralazine, sodium nitroprusside, alpha-methyldopa, and trimethaphan camsylate) used singly or in combination." | 1.26 | Catecholamine-associated refractory hypertension following acute intracranial hemorrhage: control with propranolol. ( Baldwin, CA; Feibel, JH; Joynt, RJ, 1981) |
| "To assess the incidence and severity of cardiac arrhythmias in the acute period following a cerebrovascular accident (CVA), 30 patients with a CVA in a stroke intensive care unit had 24 hours of dynamic ECG recordings." | 1.26 | Cardiac arrhythmias in patients with acute cerebrovascular accidents. ( Fletcher, GF; Jacobs, WC; Mikolich, JR, 1981) |
| "Phentolamine, that is an adrenergic blocking agent, relieved the early spam remarkably, but it was less effective on the late spam." | 1.25 | [Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)]. ( Noda, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, H | 1 |
| Kawaguchi, M | 1 |
| Inoue, S | 1 |
| Hirai, K | 1 |
| Furuya, H | 1 |
| Walter, P | 3 |
| Neil-Dwyer, G | 6 |
| Cruickshank, JM | 6 |
| Feibel, JH | 1 |
| Baldwin, CA | 1 |
| Joynt, RJ | 1 |
| Mikolich, JR | 1 |
| Jacobs, WC | 1 |
| Fletcher, GF | 1 |
| Cameron, MM | 1 |
| Haas, RH | 1 |
| Lane, J | 1 |
| Doshi, B | 1 |
| O'Gorman, P | 1 |
| Falk, RH | 1 |
| Casscells, W | 1 |
| Boullin, DJ | 1 |
| Mohan, J | 1 |
| Nagai, H | 1 |
| Noda, S | 2 |
| Mabe, H | 1 |
| Wang, ML | 1 |
| Cruickshank, J | 1 |
| Stratton, C | 1 |
| Marion, DW | 1 |
| Segal, R | 1 |
| Thompson, ME | 1 |
| Petruk, KC | 2 |
| West, GR | 1 |
| Marriott, MR | 1 |
| McIntyre, JW | 2 |
| Overton, TR | 2 |
| Weib, BK | 1 |
| Weir, BK | 1 |
| Aitken, RR | 1 |
| Drake, CG | 1 |
| Dwyer, GN | 1 |
5 trials available for propranolol and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Beneficial effects of adrenergic blockade in patients with subarachnoid haemorrhage.
Topics: Adolescent; Adult; Aged; Aneurysm; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1982 |
Adrenergic blockade in subarachnoid haemorrhage.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Humans; Ischemic Attack, Transient; Pheno | 1976 |
Effect of propranolol and phentolamine on myocardial necrosis after subarachnoid haemorrhage.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; Male; Mid | 1978 |
Beta-blockade benefits patients following a subarachnoid haemorrhage.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Electrocardiog | 1985 |
Beta-blockers, plasma total creatine kinase and creatine kinase myocardial isoenzyme, and the prognosis of subarachnoid hemorrhage.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Creatine Kinase; Doubl | 1986 |
15 other studies available for propranolol and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
The effects of beta-adrenoceptor antagonists on proinflammatory cytokine concentrations after subarachnoid hemorrhage in rats.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Disease Mo | 2009 |
Catecholamine-associated refractory hypertension following acute intracranial hemorrhage: control with propranolol.
Topics: Adult; Aged; Antihypertensive Agents; Cerebral Hemorrhage; Epinephrine; Female; Humans; Hypertension | 1981 |
Cardiac arrhythmias in patients with acute cerebrovascular accidents.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Cerebrovascular Disorders; Electrocardiography; Female; H | 1981 |
The effect of oral propranolol upon the ECG changes occurring in subarachnoid haemorrhage.
Topics: Administration, Oral; Adult; Electrocardiography; Female; Humans; Male; Middle Aged; Propranolol; Su | 1975 |
Effects of drugs on myocardial necrosis after subarachnoid haemorrhage.
Topics: Humans; Myocardium; Necrosis; Phentolamine; Propranolol; Subarachnoid Hemorrhage | 1978 |
Effects of (+) and (-)-propranolol on the responses of the human isolated basilar artery to cerebrospinal fluid obtained from patients with subarachnoid haemorrhage and cerebral arterial spasm.
Topics: Basilar Artery; Cerebral Arterial Diseases; Cerebrospinal Fluid; Female; Humans; In Vitro Techniques | 1977 |
Experimental cerebral vasospasm. Part 2: effects of vasoactive drugs and sympathectomy on early and late spasm.
Topics: Animals; Circle of Willis; Disease Models, Animal; Dogs; Ischemic Attack, Transient; Isoxsuprine; Me | 1975 |
[Experimental Subarachnoid hemmorrhage in dogs--effect of various drugs and sympathectomy on cerebral arterial spasm (author's transl)].
Topics: Animals; Autonomic Agents; Cerebral Arteries; Dogs; Ischemic Attack, Transient; Isoxsuprine; Methyse | 1975 |
[A random sample study of therapeutic effect of beta-receptor blocking agents in patients with subarachnoid hemorrhage].
Topics: Adolescent; Adult; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Propranolol; Rando | 1991 |
Beta-blocker brain concentrations in man.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Brain Chemistry; Cats; Humans; Lipid Metabolism; Met | 1985 |
Subarachnoid hemorrhage and the heart.
Topics: Adult; Arrhythmias, Cardiac; Bibliographies as Topic; Catecholamines; Coronary Disease; Electrocardi | 1986 |
Cerebral blood flow following induced subarachnoid hemorrhage in the monkey.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Cent | 1972 |
Some effects of propranolol on the cardiovascular responses of the monkey to simulated subarachnoid haemorrhage.
Topics: Animals; Arrhythmia, Sinus; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Ele | 1972 |
A technique of anesthesia with induced hypotension for surgical correction of intracranial aneurysms.
Topics: Anesthesia, General; Blood Pressure Determination; Female; Halothane; Humans; Hypotension, Controlle | 1974 |
Proceedings: Electrocardiographic changes in subarachnoid haemorrhage: role of catecholamines and effects of beta-blockade.
Topics: Administration, Oral; Adult; Catecholamines; Electrocardiography; Female; Heart; Humans; Male; Norme | 1974 |