propranolol has been researched along with Squamous Cell Carcinoma of Head and Neck in 3 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Squamous Cell Carcinoma of Head and Neck: The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One week after starting propranolol treatment, all rats were submitted to chemical induction of oral carcinogenesis with 4-nitroquinoline-1-oxide (4NQO)." | 3.96 | Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion. ( Bernabé, DG; Biasoli, ÉR; Cecilio, HP; Furuse, C; Kayahara, GM; Miyahara, GI; Oliveira, SHP; Pereira, KM; Valente, VB, 2020) |
| "Propranolol (PPL) has been suggested as an option for the treatment of various types of cancer." | 1.72 | Propranolol inhibits cell viability and expression of the pro-tumorigenic proteins Akt, NF-ĸB, and VEGF in oral squamous cell carcinoma. ( Bernabé, DG; Oliveira, SHP; Shibuya, CM; Tjioe, KC, 2022) |
| "Propranolol treatment also enhanced the effects of γ-irradiation on cell viability." | 1.38 | Propranolol as a novel adjunctive treatment for head and neck squamous cell carcinoma. ( Enepekides, DJ; Irwin, MS; Wolter, JK; Wolter, NE, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Shibuya, CM | 1 |
| Tjioe, KC | 1 |
| Oliveira, SHP | 2 |
| Bernabé, DG | 2 |
| Cecilio, HP | 1 |
| Valente, VB | 1 |
| Pereira, KM | 1 |
| Kayahara, GM | 1 |
| Furuse, C | 1 |
| Biasoli, ÉR | 1 |
| Miyahara, GI | 1 |
| Wolter, NE | 1 |
| Wolter, JK | 1 |
| Enepekides, DJ | 1 |
| Irwin, MS | 1 |
3 other studies available for propranolol and Squamous Cell Carcinoma of Head and Neck
| Article | Year |
|---|---|
Propranolol inhibits cell viability and expression of the pro-tumorigenic proteins Akt, NF-ĸB, and VEGF in oral squamous cell carcinoma.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Humans; Mouth Neoplasms; NF-kapp | 2022 |
Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion.
Topics: 4-Nitroquinoline-1-oxide; Adrenergic beta-Antagonists; Animals; Carcinogenesis; Carcinogens; Cytokin | 2020 |
Propranolol as a novel adjunctive treatment for head and neck squamous cell carcinoma.
Topics: Adrenergic beta-Antagonists; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumo | 2012 |