Page last updated: 2024-11-03

propranolol and Skin Ulcer

propranolol has been researched along with Skin Ulcer in 20 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

ExcerptRelevanceReference
"Propranolol is a valuable therapeutic alternative for treatment of ulcerated haemangiomas and effectively reduces pain."9.22Role of propranolol in ulcerated haemangioma of head and neck: a prospective comparative study. ( Gangopadhyay, AN; Gupta, DK; Pandey, V; Sharma, SP; Tiwari, P, 2016)
"A 33-day-old female with an ulcerated infantile hemangioma (IH) undergoing oral therapy with propranolol 2 mg/kg per day developed hyperkalemia and hyperphosphatemia 24 h after starting medication."7.78Tumor lysis syndrome after propranolol therapy in ulcerative infantile hemangioma: rare complication or incidental finding? ( Buffon, RB; Cavalli, R; Colli, AM; de Souza, M; Gelmetti, C, 2012)
"Propranolol was given to 20 patients with IH, who suffered from ulceration at the start of treatment (mean age at onset of treatment, 3."5.37Propranolol, a very promising treatment for ulceration in infantile hemangiomas: a study of 20 cases with matched historical controls. ( Hermans, DJ; Schultze Kool, LJ; van Beynum, IM; van de Kerkhof, PC; van der Vleuten, CJ; Wijnen, MH, 2011)
"Propranolol appears to be an effective and well-tolerated treatment for ulcerated IH."5.37Propranolol for treatment of ulcerated infantile hemangiomas. ( Barbarot, S; Bodak, N; Hadj-Rabia, S; Hamel-Teillac, D; Kupfer-Bessaguet, I; Lacour, JP; Léauté-Labrèze, C; Mazereeuw-Hautier, J; Naouri, M; Nguyen, JM; Saint-Jean, M; Stalder, JF; Vabres, P, 2011)
"Hemangioma is the most common tumor of infancy."5.35[Response to oral propranolol therapy for ulcerated hemangiomas in infancy]. ( Michel, JL; Patural, H, 2009)
"Propranolol is a valuable therapeutic alternative for treatment of ulcerated haemangiomas and effectively reduces pain."5.22Role of propranolol in ulcerated haemangioma of head and neck: a prospective comparative study. ( Gangopadhyay, AN; Gupta, DK; Pandey, V; Sharma, SP; Tiwari, P, 2016)
"A 33-day-old female with an ulcerated infantile hemangioma (IH) undergoing oral therapy with propranolol 2 mg/kg per day developed hyperkalemia and hyperphosphatemia 24 h after starting medication."3.78Tumor lysis syndrome after propranolol therapy in ulcerative infantile hemangioma: rare complication or incidental finding? ( Buffon, RB; Cavalli, R; Colli, AM; de Souza, M; Gelmetti, C, 2012)
"Infantile hemangioma is the most common vascular tumor of childhood."2.49[What's new about infantile hemangiomas?]. ( Dreyfus, I; Maza, A; Mazereeuw-Hautier, J, 2013)
"Infantile hemangiomas are the most common vascular tumors in childhood."1.56Evaluation of Clinical Properties and Treatment Responses of Infantile Hemangioma. ( Azizoglu, M; Corapcioglu, F; Demirsoy, U; Yildirimcakar, D, 2020)
"Oral propranolol is now the treatment of choice in many situations."1.39Ulcerated nasal infantile haemangioma treated by oral propranolol. ( Al Dosari, S; Riad, H, 2013)
"Propranolol was given to 20 patients with IH, who suffered from ulceration at the start of treatment (mean age at onset of treatment, 3."1.37Propranolol, a very promising treatment for ulceration in infantile hemangiomas: a study of 20 cases with matched historical controls. ( Hermans, DJ; Schultze Kool, LJ; van Beynum, IM; van de Kerkhof, PC; van der Vleuten, CJ; Wijnen, MH, 2011)
"Propranolol appears to be an effective and well-tolerated treatment for ulcerated IH."1.37Propranolol for treatment of ulcerated infantile hemangiomas. ( Barbarot, S; Bodak, N; Hadj-Rabia, S; Hamel-Teillac, D; Kupfer-Bessaguet, I; Lacour, JP; Léauté-Labrèze, C; Mazereeuw-Hautier, J; Naouri, M; Nguyen, JM; Saint-Jean, M; Stalder, JF; Vabres, P, 2011)
" A dosage of 2 mg/kg/d, is usually employed with a dosing interval of 8 hours."1.37[Propranolol in the treatment of infantile hemangioma: clinical effectiveness, risks, and recommendations]. ( López-Gutiérrez, JC; Ruiz-Rodriguez, R; Sánchez-Carpintero, I, 2011)
"Hemangioma is the most common tumor of infancy."1.35[Response to oral propranolol therapy for ulcerated hemangiomas in infancy]. ( Michel, JL; Patural, H, 2009)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's14 (70.00)24.3611
2020's3 (15.00)2.80

Authors

AuthorsStudies
Tirelli, LL1
Luna, PC1
Panizzardi, AA1
Larralde, M1
Yildirimcakar, D1
Demirsoy, U1
Azizoglu, M1
Corapcioglu, F1
Ji, Y1
Yang, K1
Zhou, J1
Zhang, X1
Xiang, B1
Jiang, X1
Xu, X1
Qiu, T1
Dai, S1
Kong, F1
Lu, G1
Qiu, Q1
Zhang, Y1
Chen, S1
Babic, V1
Schoeffler, A1
Moawad, S1
Mainard, L1
Schmutz, JL1
Bursztejn, AC1
Dreyfus, I1
Maza, A1
Mazereeuw-Hautier, J2
Luu, M1
Frieden, IJ1
Al Dosari, S1
Riad, H1
Tiwari, P1
Pandey, V1
Gangopadhyay, AN1
Sharma, SP1
Gupta, DK1
Lie, E1
Püttgen, KB1
Cheng, CE1
Friedlander, SF1
Léauté-Labrèze, C2
Harper, JI1
Hoeger, PH1
Yu, X1
Zhang, J1
Wu, Z1
Liu, M1
Chen, R1
Gu, Y1
Li, M1
Yao, Z1
Michel, JL1
Patural, H1
Hermans, DJ1
van Beynum, IM1
Schultze Kool, LJ1
van de Kerkhof, PC1
Wijnen, MH1
van der Vleuten, CJ1
Saint-Jean, M1
Bodak, N1
Hamel-Teillac, D1
Kupfer-Bessaguet, I1
Lacour, JP1
Naouri, M1
Vabres, P1
Hadj-Rabia, S1
Nguyen, JM1
Stalder, JF1
Barbarot, S1
Kim, LHC1
Hogeling, M1
Wargon, O1
Jiwane, A1
Adams, S1
Sánchez-Carpintero, I1
Ruiz-Rodriguez, R1
López-Gutiérrez, JC1
Cavalli, R1
Buffon, RB1
de Souza, M1
Colli, AM1
Gelmetti, C1
Armour, K1
Lowe, P1
Hoffbrand, BI1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"'' Efficacy of Propranolol in the Treatment of Infantile Hemangioma"[NCT04684667]Phase 2100 participants (Anticipated)Interventional2021-01-01Not yet recruiting
A Comparative Study of the Use of Beta Blocker and Oral Corticosteroid in the Treatment of Proliferative and Involuting Cutaneous Infantile Hemangioma[NCT01072045]Phase 250 participants (Actual)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for propranolol and Skin Ulcer

ArticleYear
[Rare presentations of infantile hemangiomas: 4 cases].
    Annales de dermatologie et de venereologie, 2018, Volume: 145, Issue:12

    Topics: Biopsy; Buttocks; Delayed Diagnosis; Erythema; Facial Neoplasms; Female; Foot Diseases; Hemangioma,

2018
[What's new about infantile hemangiomas?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:7

    Topics: Hemangioma; Humans; Infant, Newborn; Propranolol; Skin Neoplasms; Skin Ulcer; Vasodilator Agents

2013
Haemangioma: clinical course, complications and management.
    The British journal of dermatology, 2013, Volume: 169, Issue:1

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Cicatrix; Congenita

2013
Infantile hemangiomas, complications and treatments.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Airway Obstruction; Drug Therapy, Combination;

2016
Infantile haemangioma.
    Lancet (London, England), 2017, 07-01, Volume: 390, Issue:10089

    Topics: Adrenergic beta-Antagonists; Heart Failure; Hemangioma; Humans; Infant; Propranolol; Respiratory Dis

2017
LUMBAR syndrome: A case manifesting as cutaneous infantile hemangiomas of the lower extremity, perineum and gluteal region, and a review of published work.
    The Journal of dermatology, 2017, Volume: 44, Issue:7

    Topics: Abnormalities, Multiple; Adrenergic beta-Antagonists; Biopsy; Buttocks; Female; Hemangioma; Humans;

2017

Trials

1 trial available for propranolol and Skin Ulcer

ArticleYear
Role of propranolol in ulcerated haemangioma of head and neck: a prospective comparative study.
    Oral and maxillofacial surgery, 2016, Volume: 20, Issue:1

    Topics: Acetaminophen; Administration, Oral; Drug Therapy, Combination; Female; Head and Neck Neoplasms; Hem

2016

Other Studies

13 other studies available for propranolol and Skin Ulcer

ArticleYear
[Management of ulcers on a segmental hemangioma: A combination of systemic and topical therapies in two pediatric cases].
    Archivos argentinos de pediatria, 2022, Volume: 120, Issue:5

    Topics: Administration, Oral; Child; Hemangioma; Humans; Infant; Propranolol; Skin Neoplasms; Skin Ulcer; Tr

2022
Evaluation of Clinical Properties and Treatment Responses of Infantile Hemangioma.
    Journal of drugs in dermatology : JDD, 2020, Dec-01, Volume: 19, Issue:12

    Topics: Age Factors; Esthetics; Facial Neoplasms; Female; Glucocorticoids; Hemangioma; Hemorrhage; Humans; I

2020
Propranolol for the treatment of ulcerated infantile hemangiomas: A prospective study.
    Journal of the American Academy of Dermatology, 2022, Volume: 86, Issue:5

    Topics: Adrenergic beta-Antagonists; Hemangioma; Hemangioma, Capillary; Humans; Infant; Propranolol; Prospec

2022
Ulcerated nasal infantile haemangioma treated by oral propranolol.
    Dermatology online journal, 2013, May-15, Volume: 19, Issue:5

    Topics: Administration, Oral; Drug Administration Schedule; Female; Hemangioma, Capillary; Humans; Infant; N

2013
Corticosteroids as an adjunct to propranolol for infantile haemangiomas complicated by recalcitrant ulceration.
    The British journal of dermatology, 2017, Volume: 176, Issue:4

    Topics: Administration, Oral; Chronic Disease; Drug Therapy, Combination; Glucocorticoids; Hemangioma; Human

2017
[Response to oral propranolol therapy for ulcerated hemangiomas in infancy].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16, Issue:12

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Female; Forearm; Hemangioma; Humans; Infant; Prop

2009
Propranolol, a very promising treatment for ulceration in infantile hemangiomas: a study of 20 cases with matched historical controls.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:5

    Topics: Adrenergic beta-Antagonists; Female; Head and Neck Neoplasms; Hemangioma; Humans; Infant; Male; Prop

2011
Propranolol for treatment of ulcerated infantile hemangiomas.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:5

    Topics: Adrenergic beta-Antagonists; Child; Child, Preschool; Female; Head and Neck Neoplasms; Hemangioma; H

2011
Propranolol: useful therapeutic agent for the treatment of ulcerated infantile hemangiomas.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:4

    Topics: Adrenergic beta-Antagonists; Female; Follow-Up Studies; Hemangioma; Humans; Infant; Male; Propranolo

2011
[Propranolol in the treatment of infantile hemangioma: clinical effectiveness, risks, and recommendations].
    Actas dermo-sifiliograficas, 2011, Volume: 102, Issue:10

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Bradycardia; Bronchial Spasm; Clinical Trials

2011
Tumor lysis syndrome after propranolol therapy in ulcerative infantile hemangioma: rare complication or incidental finding?
    Dermatology (Basel, Switzerland), 2012, Volume: 224, Issue:2

    Topics: Antineoplastic Agents; Female; Hemangioma, Capillary; Humans; Hyperkalemia; Hyperphosphatemia; Infan

2012
Complicated lichenoid drug eruption.
    The Australasian journal of dermatology, 2005, Volume: 46, Issue:1

    Topics: Antiviral Agents; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Hepatitis C; Hum

2005
Peripheral skin necrosis complicating beta-blockade.
    British medical journal, 1979, Apr-21, Volume: 1, Issue:6170

    Topics: Aged; Female; Humans; Male; Middle Aged; Necrosis; Propranolol; Skin; Skin Ulcer; Toes

1979