Page last updated: 2024-11-03

propranolol and Sick Sinus Node Syndrome

propranolol has been researched along with Sick Sinus Node Syndrome in 52 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Baroreflex sensitivity was measured by the heart rate response to the transient rise in blood pressure induced by phenylephrine, in 11 patients with carotid sinus syndrome, 6 patients with sick sinus syndrome and nine age and blood pressure matched controls."7.67Baroreflex sensitivity measured by the phenylephrine pressor test in patients with carotid sinus and sick sinus syndromes. ( Chan, SL; Dehn, TC; Morley, CA; Perrins, EJ; Sutton, R, 1984)
"Baroreflex sensitivity was measured by the heart rate response to the transient rise in blood pressure induced by phenylephrine, in 11 patients with carotid sinus syndrome, 6 patients with sick sinus syndrome and nine age and blood pressure matched controls."3.67Baroreflex sensitivity measured by the phenylephrine pressor test in patients with carotid sinus and sick sinus syndromes. ( Chan, SL; Dehn, TC; Morley, CA; Perrins, EJ; Sutton, R, 1984)
"Beta blockers in patients with sick sinus syndrome (SSS) may prevent supraventricular arrhythmias, systemic hypertension and myocardial ischemia, but may cause excessive depression of sinus node function."2.67Comparison of effects of propranolol versus pindolol on sinus rate and pacing frequency in sick sinus syndrome. ( Antman, EM; Bhatia, S; Cantillon, C; Fish, RD; Friedman, PL; Lamas, GA; McGowan, N; Strickberger, SA, 1993)
"Holter monitoring revealed ectopic atrial tachycardia during tachyarrhythmia and occasional sinus pauses with junctional escape beats."2.61Severe congenital RYR1-associated myopathy complicated with atrial tachycardia and sinus node dysfunction: a case report. ( Abe, Y; Hayakawa, I; Kubota, M; Ono, H, 2019)
"Sinus node dysfunction is a recognized problem following surgery for congenital heart disease."1.28Electrophysiologic evaluation of sinus node dysfunction in postoperative children and young adults utilizing combined autonomic blockade. ( Garson, A; Gillette, PC; Marcus, B, 1991)
"In these patients intrinsic sinus node disease can be assumed."1.27[Functional autonomic blockade in the diagnosis of functional sinus node disorders]. ( Kasper, W; Meinertz, T; Meyer, J; Pop, T; Steppert, C; Treese, N, 1984)
"In patients with sick sinus syndrome the corrected SNRT was abnormal (greater than 450 msec) in 16 (48."1.27Sinus node function after autonomic blockade in normals and in sick sinus syndrome. ( Bahl, VK; Balachander, J; Gupta, MP; Jaishankar, S; Sethi, KK, 1984)
"Patients with sick sinus syndrome frequently have abnormalities of "intrinsic" atrioventricular nodal conduction unmasked by autonomic blockade."1.27Differential effects of autonomic blockade on sinus and atrioventricular nodal function in normals and in intrinsic sinus node dysfunction. ( Balachandar, J; Gupta, MP; Jaishankar, S; Sethi, KK, 1986)
"The diagnosis of sick sinus syndrome (SSS) was made according to history data, clinical manifestations of the disease, and ECG data of SSS."1.26[Diagnostic significance of frequent atrial stimulation against a background of drug denervation in the sick sinus syndrome]. ( Frolov, AI, 1982)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199037 (71.15)18.7374
1990's10 (19.23)18.2507
2000's4 (7.69)29.6817
2010's1 (1.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayakawa, I1
Abe, Y1
Ono, H1
Kubota, M1
Mine, T1
Shimizu, H2
Hiromoto, K1
Furukawa, Y2
Kanemori, T2
Nakamura, H1
Masuyama, T1
Ohyanagi, M2
Tan, BH1
Ishikawa, S1
Sawada, K1
Tanahashi, Y1
Tsuzuki, J1
Hattori, M1
Kato, R1
Sotohata, I1
Toyama, J1
Hayakawa, K1
Kato, T2
Shul'man, VA3
Szatmáry, LJ1
Morley, CA1
Dehn, TC1
Perrins, EJ1
Chan, SL1
Sutton, R1
Szatmáry, L2
Jouve, A1
Pinot, JJ1
Torresani, J1
Pop, T3
Treese, N3
Kasper, W3
Meinertz, T3
Schuster, CJ1
Schreiner, G1
Meyer, J2
Steppert, C1
Sethi, KK2
Jaishankar, S2
Balachander, J1
Bahl, VK1
Gupta, MP2
Benchimol, CB1
Barbosa Filho, J1
Ginefra, P1
Benchimol, AB1
de Carvalho, AP1
von Mengden, HJ1
Kang, PS1
Gomes, JA2
El-Sherif, N1
Alboni, P3
Malcarne, C1
Pedroni, P2
Masoni, A1
Narula, OS1
Medvedowsky, JL1
Barnay, C1
Coste, A1
Pisapia, A1
Fabry-Delaigue, R1
Duchêne-Marullaz, P1
Lemaire, P1
Chambon, M1
Frolov, AI1
Kontani, K1
Matsushita, S1
Matsunuma, K1
Ikeda, T1
Inasaka, T1
Blanc, JJ1
Gestin, E1
Guillerm, D1
Boschat, J1
Penther, P1
Mobilij, A1
D'Annunzio, E1
Zambelli, P1
Havelda, CJ1
Vallin, HO1
Edhag, KO1
Strickberger, SA1
Fish, RD1
Lamas, GA1
Cantillon, C1
Bhatia, S1
McGowan, N1
Antman, EM1
Friedman, PL1
Tsuchioka, Y1
Shimizu, W1
Karakawa, S1
Mukai, J1
Nagata, K1
Yamagata, T1
Okamoto, M1
Matuura, H1
Kajiyama, G1
Nanthakumar, K1
Dorian, P1
Paquette, M1
Hutchison, S1
Andrews, J1
Newman, D1
Stein, R1
Medeiros, CM1
Rosito, GA1
Zimerman, LI1
Ribeiro, JP1
Curry, PV1
Rowland, E1
Krikler, DM1
Hayakawa, H1
Lai, WT1
Lai, HM1
Lin, CT1
Sheu, SH1
Hwang, YS1
Ogawa, H1
Inoue, T1
Miwa, S1
Fujimoto, T1
Ohnishi, Y1
Fukuzaki, H1
Marcus, B2
Gillette, PC2
Garson, A2
Mitsuoka, T1
Ueyama, C1
Matsumoto, Y1
Hashiba, K1
Endo, T1
Hiejima, K1
Ziesenhenn, K1
Münnich, R1
Paparella, N2
Cappato, R1
Candini, GC1
Antonioli, GE1
Aronow, WS1
Omori, I1
Inoue, D1
Shirayama, T1
Asayama, J1
Katsume, H1
Nakagawa, M1
Piwowarska, W4
Mroczek-Czernecka, D4
Bacior, B4
Matiushin, GV2
Zal'tsberg, SV1
Kuga, K1
Yamaguchi, I1
Sugishita, Y1
Ito, I1
Chen, JH1
Lien, WP1
Chen, JJ1
Lin, JL1
Peng, HC1
Kusaev, VV1
Balog, AI1
Balachandar, J1
Michelucci, A1
Padeletti, L1
Fradella, GA1
Monizzi, D1
Giomi, A1
Fantini, F1
Pirani, R1

Reviews

5 reviews available for propranolol and Sick Sinus Node Syndrome

ArticleYear
Severe congenital RYR1-associated myopathy complicated with atrial tachycardia and sinus node dysfunction: a case report.
    Italian journal of pediatrics, 2019, Dec-19, Volume: 45, Issue:1

    Topics: Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Genetic Predisposit

2019
[Sinus node function and its clinical evaluation].
    Nihon Ika Daigaku zasshi, 1983, Volume: 50, Issue:3

    Topics: Action Potentials; Animals; Atropine; Cardiac Pacing, Artificial; Electrocardiography; Humans; In Vi

1983
[Functional tests in the diagnosis of the sick sinus syndrome].
    Kardiologiia, 1984, Volume: 24, Issue:12

    Topics: Atropine; Carotid Sinus; Electrocardiography; Electrodiagnosis; Exercise Test; Heart Conduction Syst

1984
[Dysfunction of the sinus node].
    Arquivos brasileiros de cardiologia, 1982, Volume: 38, Issue:5

    Topics: Animals; Atropine; Electrocardiography; Heart Diseases; Heart Function Tests; Heart Rate; Humans; Is

1982
Management of supraventricular tachyarrhythmias.
    Comprehensive therapy, 1989, Volume: 15, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Bradycardia; Huma

1989

Trials

1 trial available for propranolol and Sick Sinus Node Syndrome

ArticleYear
Comparison of effects of propranolol versus pindolol on sinus rate and pacing frequency in sick sinus syndrome.
    The American journal of cardiology, 1993, Jan-01, Volume: 71, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Capsules; Cardiac Pacing, Artificial; Double-Blind Me

1993

Other Studies

46 other studies available for propranolol and Sick Sinus Node Syndrome

ArticleYear
Beat-to-beat QT interval variability is primarily affected by the autonomic nervous system.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2008, Volume: 13, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Flutter; Atropine; Autonomic Nervous Syst

2008
Sinus slowing caused by adenosine-5'-triphosphate in patients with and without sick sinus syndrome under various autonomic states.
    Journal of electrocardiology, 2004, Volume: 37, Issue:4

    Topics: Adenosine Triphosphate; Aged; Atrial Function; Atropine; Cardiac Catheterization; Depression, Chemic

2004
Experimental studies on sick sinus syndrome: relationship of extent of right atrial lesions to subsidiary pacemaker shift and its function.
    American heart journal, 1983, Volume: 105, Issue:4

    Topics: Animals; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart Arrest; Heart Atria; H

1983
Autonomic blockade and sick sinus syndrome. New concept in the interpretation of electrophysiological and Holter data.
    European heart journal, 1984, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Atropine; Autonomic Nerve Block; Cardiac Pacing, Artificia

1984
Baroreflex sensitivity measured by the phenylephrine pressor test in patients with carotid sinus and sick sinus syndromes.
    Cardiovascular research, 1984, Volume: 18, Issue:12

    Topics: Aged; Blood Pressure; Carotid Sinus; Electrocardiography; Female; Humans; Male; Phenylephrine; Press

1984
Comparative study of electrophysiological and Holter monitoring data in estimating sinoatrial function. Significance of intrinsic heart rate in disclosing autonomic sinus node dysfunction.
    Cardiology, 1983, Volume: 70, Issue:4

    Topics: Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Block; Hear

1983
[Effect of nifedipine on sinus node and atrioventricular node function following autonomic blockade in the human].
    Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:12

    Topics: Adolescent; Adult; Aged; Atrioventricular Node; Atropine; Autonomic Nerve Block; Electrocardiography

1983
[Functional autonomic blockade in the diagnosis of functional sinus node disorders].
    Deutsche medizinische Wochenschrift (1946), 1984, Jan-20, Volume: 109, Issue:3

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nerve Block; Cardiac Catheterization; Electrocardiograp

1984
Sinus node function after autonomic blockade in normals and in sick sinus syndrome.
    International journal of cardiology, 1984, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Cardiac Pacing, Artificial; Female; Hea

1984
[Transient sinus node arrest-a dysregulation of the autonomic nervous system (author's transl)].
    Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:4

    Topics: Adult; Atropine; Autonomic Nervous System Diseases; Bradycardia; Electrocardiography; Female; Heart

1982
Differential effects of functional autonomic blockade on the variables of sinus nodal automaticity in sick sinus syndrome.
    The American journal of cardiology, 1982, Feb-01, Volume: 49, Issue:2

    Topics: Age Factors; Atropine; Autonomic Nerve Block; Cardiac Pacing, Artificial; Electrophysiology; Heart R

1982
Electrophysiology of normal sinus node with and without autonomic blockade.
    Circulation, 1982, Volume: 65, Issue:6

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Bundle of His; Cardiac Pacing, Artifici

1982
Electrophysiological effect of overdrive suppression and combined autonomic blockade with propranolol and atropine in patients with sinus node dysfunction.
    European heart journal, 1982, Volume: 3, Issue:1

    Topics: Adult; Aged; Atropine; Cardiac Pacing, Artificial; Female; Heart Rate; Humans; Male; Middle Aged; Pr

1982
Long-term observation of cardiac rhythm and automaticity in the dog after excision of the sinoatrial node.
    Journal of electrocardiology, 1982, Volume: 15, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Atropine; Dogs; Electrocardiography; Electrodes, Implanted; Heart Con

1982
[Diagnostic significance of frequent atrial stimulation against a background of drug denervation in the sick sinus syndrome].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1982, Volume: 5, Issue:2

    Topics: Adult; Aged; Atropine; Cardiac Catheterization; Diagnosis, Differential; Electric Stimulation; Elect

1982
Altered autonomic mechanisms in the sick sinus syndrome and diurnal variations in the parameters of sinus node function.
    Japanese circulation journal, 1980, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Blood Pressure; Cardiac Pacing, Artific

1980
Response of normal and abnormal sinus node to right ventricular stimulation.
    The American journal of cardiology, 1981, Volume: 48, Issue:3

    Topics: Adult; Aged; Atropine; Autonomic Nerve Block; Cardiac Pacing, Artificial; Electrocardiography; Elect

1981
[Modern methods of evaluation of sinus node function by means of endocardiac electrophysiological study].
    Minerva medica, 1980, Aug-25, Volume: 71, Issue:30

    Topics: Atropine; Cardiac Pacing, Artificial; Electrocardiography; Heart Rate; Humans; Propranolol; Sick Sin

1980
Sick sinus syndrome.
    The Journal of the Kentucky Medical Association, 1980, Volume: 78, Issue:11

    Topics: Aged; Atropine; Electrocardiography; Female; Humans; Propranolol; Sick Sinus Syndrome

1980
Heat rate responses in patients with sinus node disease compared to controls: physiological implications and diagnostic possibilities.
    Clinical cardiology, 1980, Volume: 3, Issue:6

    Topics: Aged; Atropine; Autonomic Nervous System; Carotid Sinus; Exercise Test; Female; Heart Rate; Humans;

1980
[The effects of pharmacological autonomic blockade on the conduction system in patients with and without sinus node dysfunction].
    Kokyu to junkan. Respiration & circulation, 1993, Volume: 41, Issue:2

    Topics: Atropine; Autonomic Nervous System; Electrophysiology; Female; Heart Conduction System; Humans; Male

1993
Effect of physiological mechanical perturbations on intact human myocardial repolarization.
    Cardiovascular research, 2000, Jan-14, Volume: 45, Issue:2

    Topics: Action Potentials; Aged; Atropine; Autonomic Agents; Cardiac Pacing, Artificial; Female; Heart; Hear

2000
Intrinsic sinus and atrioventricular node electrophysiologic adaptations in endurance athletes.
    Journal of the American College of Cardiology, 2002, Mar-20, Volume: 39, Issue:6

    Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Adult; Atrioventricular Node; Atropine; Elec

2002
Dual-demand pacing for refractory atrioventricular re-entry tachycardia.
    Pacing and clinical electrophysiology : PACE, 1979, Volume: 2, Issue:2

    Topics: Adult; Amiodarone; Electrocardiography; Female; Follow-Up Studies; Heart Conduction System; Heart Ve

1979
[Sick sinus syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:11

    Topics: Adrenergic beta-Antagonists; Atropine; Calcium Channel Blockers; Cardiac Pacing, Artificial; Electro

1991
Is sick sinus syndrome an adenosine-mediated disease? Effects of intravenous aminophylline on sick sinus node function after pharmacologic autonomic blockade.
    Chest, 1991, Volume: 99, Issue:4

    Topics: Adenosine; Aminophylline; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female

1991
Heart rate responses to autonomic drugs in sick sinus syndrome--correlation with syncope and electrophysiologic data.
    Japanese circulation journal, 1991, Volume: 55, Issue:1

    Topics: Adult; Aged; Atropine; Autonomic Agents; Autonomic Nervous System; Electrocardiography; Female; Hear

1991
Electrophysiologic evaluation of sinus node dysfunction in postoperative children and young adults utilizing combined autonomic blockade.
    Clinical cardiology, 1991, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Arrhythmia, Sinus; Atropine; Autonomic Nervous System; Child; Child, Preschool; E

1991
Influences of autonomic changes on the sinus node recovery time in patients with sick sinus syndrome.
    Japanese heart journal, 1990, Volume: 31, Issue:5

    Topics: Adult; Aged; Atropine; Autonomic Nervous System; Cardiac Pacing, Artificial; Circadian Rhythm; Femal

1990
Intrinsic heart rate in children and young adults: an index of sinus node function isolated from autonomic control.
    American heart journal, 1990, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Arrhythmia, Sinus; Atropine; Child; Electrocardiography; Female; Heart Rate; Huma

1990
[Sick sinus syndrome--indication of pacemaker implantation].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:2

    Topics: Atropine; Electrocardiography, Ambulatory; Electrophysiology; Exercise Test; Heart Function Tests; H

1990
[Routine diagnosis in patients with latent sinus node syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1990, Apr-01, Volume: 45, Issue:7

    Topics: Aged; Atropine; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Rate; Humans; Male; M

1990
Reliability of transesophageal pacing in the assessment of sinus node function in patients with sick sinus syndrome.
    Pacing and clinical electrophysiology : PACE, 1989, Volume: 12, Issue:2

    Topics: Adult; Aged; Atropine; Cardiac Catheterization; Cardiac Pacing, Artificial; Esophagus; Female; Human

1989
Effect of paced cycle length on sinus node effective refractory period before and after autonomic blockade in patients with sick sinus syndrome.
    European heart journal, 1989, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nerve Block; Cardiac Pacing, Artificial; Electrocardiog

1989
Diagnostic value pharmacological autonomic blockade in patients with suspected sick sinus syndrome.
    Japanese heart journal, 1988, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Agents; Autonomic Nerve Block; Cardiac Pacing, Artifici

1988
[Paradoxical shortening of the time of restoration of sinoatrial node function after administration of obsidan in patients with sick sinus syndrome].
    Kardiologiia, 1988, Volume: 28, Issue:9

    Topics: Depression, Chemical; False Negative Reactions; Female; Humans; Middle Aged; Propranolol; Sick Sinus

1988
Assessment by autonomic blockade of age-related changes of the sinus node function and autonomic regulation in sick sinus syndrome.
    The American journal of cardiology, 1988, Feb-01, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Atropine; Autonomic Nerve Block; Autonomic

1988
Reappraisal of atrioventricular junctional pacemaker automaticity in the sick sinus syndrome. Clinical significance and the role of autonomic chronotropic influences.
    Chest, 1988, Volume: 93, Issue:6

    Topics: Adult; Aged; Atrioventricular Node; Atropine; Autonomic Nervous System; Electrophysiology; Female; H

1988
[Value of propranolol and atropine dosage for the evaluation of sinoatrial node function in the rapid atrial stimulation test].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Feb-08, Volume: 43, Issue:6

    Topics: Adult; Aged; Atropine; Dose-Response Relationship, Drug; Female; Heart Atria; Humans; Male; Middle A

1988
[Significance of autonomic block by drugs for the diagnosis and evaluation of the pathogenesis of the sick sinus syndrome].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:10

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Atropine; Autonomic Nerve Block; Diagnosis, Differential;

1987
[Rapid atrial stimulation test after pharmacologic blockade of the autonomic nervous system in symptomatic and asymptomatic sick sinus syndrome].
    Kardiologia polska, 1986, Volume: 29, Issue:11-12

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Depression, Chemical; Electrocardiograp

1986
[Evaluation of the rapid atrial stimulation test after pharmacologic blockade with propranolol and atropine].
    Kardiologia polska, 1986, Volume: 29, Issue:11-12

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Electrocardiography; Female; Heart Atri

1986
Differential effects of autonomic blockade on sinus and atrioventricular nodal function in normals and in intrinsic sinus node dysfunction.
    International journal of cardiology, 1986, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Atrioventricular Node; Atropine; Autonomic Nervous System; Cardiac Pacing,

1986
Sinus node dysfunction: new concepts and evaluation of patients with suspected sick sinus syndrome.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:8

    Topics: Aged; Atrioventricular Node; Atropine; Bundle of His; Electrocardiography; Electrophysiology; Heart

1985
Effects of pharmacologic autonomic blockade on atrial electrophysiologic properties in normal subjects and in patients with sinus node disease.
    International journal of cardiology, 1985, Volume: 8, Issue:4

    Topics: Aged; Atropine; Autonomic Nervous System; Cardiac Pacing, Artificial; Electrocardiography; Female; H

1985
[Drug blockade of the neurovegetative system in the study of sinus node function].
    Giornale italiano di cardiologia, 1985, Volume: 15, Issue:4

    Topics: Anti-Arrhythmia Agents; Atropine; Autonomic Nerve Block; Heart Rate; Humans; Prognosis; Propranolol;

1985