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propranolol and Shock, Septic

propranolol has been researched along with Shock, Septic in 31 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

ExcerptRelevanceReference
"Pregnancy is associated with a suppression of maternal specific immune responses, which process underlies the protection of fetal tissues expressing paternally inherited alloantigens."1.31Enhanced tumor necrosis factor-alpha-specific and decreased interleukin-10-specific immune responses to LPS during the third trimester of pregnancy in mice. ( Haskó, G; Németh, ZH; Papp, Z; Selmeczy, ZS; Szelényi, J; Vizi, ES, 2001)
"Amiloride prevented the increase in liquid clearance from the airspaces, indicating that this effect depended on increased uptake of sodium across the lung epithelium."1.29Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. ( Folkesson, HG; Matthay, MA; McElroy, MC; Pittet, JF; Wiener-Kronish, JP, 1994)
"Propranolol pretreatment prevented the endotoxin-induced reduction in lymphocytic beta-adrenergic receptor number (P less than ."1.28Effects of canine endotoxin shock on lymphocytic beta-adrenergic receptors. ( el-Fakahany, EE; Lee, NH; Silverman, HJ, 1990)
"DESIGN - Endotoxin shock was obtained in dogs by giving S Typhimurium endotoxin intravenously (1 mg."1.28Insulin and beta adrenergic effects during endotoxin shock: in vivo myocardial interactions. ( Law, WR; McLane, MP; Raymond, RM, 1990)
"Cardiac volume changes during septic shock could be responsible for the abnormal trends in phase angle spread and electrocardiographic data."1.28Changes in phase analysis patterns of radionuclide ventriculograms obtained from baboons during atrial pacing, septic shock, and induced myocardial infarction. ( Davies, J; Dormehl, IC; Hugo, N; Jacobs, L; Maree, M; van Gelder, AL, 1989)
"Extreme hyperinsulinism was observed in endotoxin-shock dogs made hyperglycemic by glucose infusion."1.26Hyperinsulinism in endotoxin shock dogs. ( Anderson, JH; Blackard, WG; Spitzer, JJ, 1976)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199022 (70.97)18.7374
1990's5 (16.13)18.2507
2000's1 (3.23)29.6817
2010's2 (6.45)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Brewster, R1
Lee, J1
Nguyen, E1
Ward, V1
Brosnahan, AJ1
Vulchanova, L1
Witta, SR1
Dai, Y1
Jones, BJ1
Brown, DR1
Martinez, R1
Rogers, A1
Numanoglu, A1
Rode, H1
Goodyer, AV1
Goretzki, PE1
Cavalieri, RR1
Wahl, RA1
Ellis, RJ1
McMahon, FA1
Goldfien, S1
Gerend, P1
Clark, OH1
Walvatne, CS1
Johnson, AS1
Wojcik, LJ1
Cerra, FB1
Pittet, JF1
Wiener-Kronish, JP1
McElroy, MC1
Folkesson, HG1
Matthay, MA1
Pittner, RA1
Spitzer, JA1
Vizi, ES1
Szelényi, J1
Selmeczy, ZS1
Papp, Z1
Németh, ZH1
Haskó, G1
Harken, AH1
Filkins, JP1
Markley, K1
Smallman, ET1
Briggs, LW1
Blackard, WG1
Anderson, JH1
Spitzer, JJ1
Silverman, HJ1
Lee, NH1
el-Fakahany, EE1
Law, WR1
McLane, MP1
Raymond, RM1
Dormehl, IC2
Hugo, N2
van Gelder, AL2
Maree, M2
Jacobs, L2
Davies, J1
Pieroni, RE1
Bundeally, AE1
Amdur, MO1
Levine, L1
Hall, RC1
Hodge, RL1
Berk, JL3
Hagen, JF3
Dunn, JM1
Nelson, NC1
Nelson, JL1
Weldon, WE1
Vela, AR1
Halmagyi, DF2
Kennedy, M1
Goodman, AH1
Varga, D2
Maly, G1
Koo, R1
Hinshaw, LB1
Greenfeild, LJ1
Archer, LT1
Guenter, CA1
Scobbo, RR1
Chung, EK1
Dadkar, VN1
Dadkar, NK1
Sheth, UK1
Jenkins, WL1
Beyer, WH1
Gerber, MJ1
Dochat, GR1
Sasaki, Y1
Torsti, P1
Irving, MH1
Gillett, DJ1

Reviews

1 review available for propranolol and Shock, Septic

ArticleYear
The surgical significance of the oxyhemoglobin dissociation curve.
    Surgery, gynecology & obstetrics, 1977, Volume: 144, Issue:6

    Topics: Anemia; Angina Pectoris; Animals; Blood; Diabetes Mellitus; Diphosphoglyceric Acids; Erythrocytes; H

1977

Other Studies

30 other studies available for propranolol and Shock, Septic

ArticleYear
Managing Persistent Hypertension and Tachycardia Following Septic Shock, Limb Ischemia, and Amputation: The Role for β-Blockade.
    Clinical pediatrics, 2021, Volume: 60, Issue:4-5

    Topics: Adrenergic beta-Antagonists; Amputation, Surgical; Cefepime; Child; Clindamycin; Debridement; Diagno

2021
Norepinephrine potentiates proinflammatory responses of human vaginal epithelial cells.
    Journal of neuroimmunology, 2013, Jun-15, Volume: 259, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Cell Line, Tra

2013
Fatal non-occlusive mesenteric ischemia and the use of propranolol in paediatric burns.
    Burns : journal of the International Society for Burn Injuries, 2016, Volume: 42, Issue:4

    Topics: Adrenergic beta-Antagonists; Burns; Child; Fatal Outcome; Female; Humans; Infant; Male; Mesenteric I

2016
Left ventricular function and tissue hypoxia in irreversible hemorrhagic and endotoxin shock.
    The American journal of physiology, 1967, Volume: 212, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Heart; Heart Failure; Heart Rate; Heart V

1967
Serum and tissue T3 levels in endotoxin shock in the rat.
    The Journal of surgical research, 1983, Volume: 35, Issue:3

    Topics: Animals; Endotoxins; Female; Injections, Intraperitoneal; Kidney; Liver; Methylprednisolone; Propran

1983
Cardiovascular response to acute and chronic endotoxemia in an awake, volume-resuscitated, canine model.
    Shock (Augusta, Ga.), 1995, Volume: 3, Issue:4

    Topics: Animals; Cardiovascular System; Dogs; Drug Interactions; Hemodynamics; Lipopolysaccharides; Proprano

1995
Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:2

    Topics: Amiloride; Anesthesia; Animals; Catecholamines; Epinephrine; Epithelium; Lung; Male; Metabolic Clear

1994
Shift from alpha- to beta-type adrenergic receptor-mediated responses in chronically endotoxemic rats.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: Angiotensin II; Animals; Cells, Cultured; Chlorides; Endotoxins; Escherichia coli; Glucagon; Inosito

1993
Enhanced tumor necrosis factor-alpha-specific and decreased interleukin-10-specific immune responses to LPS during the third trimester of pregnancy in mice.
    The Journal of endocrinology, 2001, Volume: 171, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Berberine; Female; Gestational A

2001
Adrenergic blockade and glucoregulation in endotoxin shock.
    Circulatory shock, 1979, Volume: 6, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose; Gluconeogenesis;

1979
Early mortality and temperature regulation in burned mice following administration of catecholamines and adrenergic receptor blocking drugs.
    The Journal of trauma, 1979, Volume: 19, Issue:7

    Topics: Animals; Blood Circulation; Body Fluids; Body Temperature Regulation; Burns; Dibenzylchlorethamine;

1979
Hyperinsulinism in endotoxin shock dogs.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:6

    Topics: Alloxan; Animals; Blood Glucose; Dogs; Escherichia coli; Glucose; Hyperinsulinism; Islets of Langerh

1976
Effects of canine endotoxin shock on lymphocytic beta-adrenergic receptors.
    Circulatory shock, 1990, Volume: 32, Issue:4

    Topics: Animals; Cyclic AMP; Dogs; Endotoxins; Lymphocytes; Propranolol; Receptors, Adrenergic, beta; Shock,

1990
Insulin and beta adrenergic effects during endotoxin shock: in vivo myocardial interactions.
    Cardiovascular research, 1990, Volume: 24, Issue:1

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Female; Glucose; Insulin; Insulin Resistance;

1990
Left ventricular volume and function changes during beta-blockade and accompanying atrial pacing.
    American journal of physiologic imaging, 1989, Volume: 4, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Cardiac Pacing, Artificial; Cardiac Volume; Heart; Heart Rate;

1989
Changes in phase analysis patterns of radionuclide ventriculograms obtained from baboons during atrial pacing, septic shock, and induced myocardial infarction.
    American journal of physiologic imaging, 1989, Volume: 4, Issue:4

    Topics: Animals; Cardiac Pacing, Artificial; Cardiac Volume; Electrocardiography; Fourier Analysis; Heart; M

1989
Bordetella pertussis as a beta-adrenergic blocking agent.
    International archives of allergy and applied immunology, 1971, Volume: 41, Issue:5

    Topics: Adrenergic beta-Antagonists; Anaphylaxis; Anemia, Hemolytic, Autoimmune; Animals; Bordetella pertuss

1971
Vasoactive hormones in endotoxin shock: a comparative study in cats and dogs.
    The Journal of physiology, 1971, Volume: 213, Issue:1

    Topics: Adrenal Glands; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cats; Central Venous Pressu

1971
The role of beta adrenergic blockade in the treatment of septic shock.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiac Output; Central Venous Pressure; D

1970
Mechanisms of change in thoracic duct lymph flow during hypotensive states.
    Annals of surgery, 1970, Volume: 171, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspirin; Capillary Permeability;

1970
Simple and combined adrenergic receptor blockade in canine endotoxinemia.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1971, Volume: 3, Issue:5

    Topics: Acid-Base Equilibrium; Adrenal Glands; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; An

1971
The treatment of shock with beta adrenergic blockade.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 104, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiac Output; Female; Glucag

1972
Effects of endotoxin on myocardial hemodynamics, performance, and metabolism during beta adrenergic blockade.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 137, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Cardiac Ou

1971
Electrocardiogram of the month. Unusual reaction to propranolol.
    The West Virginia medical journal, 1972, Volume: 68, Issue:7

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Drug Hypersensitivity; Electrocardiography; Human

1972
Experimental studies in endotoxin shock in dogs. II. Experimental evaluation of different therapeutic measures in irreversible endotoxin shock.
    The Indian journal of medical research, 1972, Volume: 60, Issue:6

    Topics: Animals; Dextrans; Dogs; Hemodynamics; Phenoxybenzamine; Propranolol; Shock, Septic

1972
Some aspects of the treatment of shock in animals.
    Journal of the South African Veterinary Association, 1972, Volume: 43, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Blood Pressure; Blood Transfusion; Cardiac Output; Digitalis Glyco

1972
The treatment of endotoxin shock by beta adrenergic blockade.
    Annals of surgery, 1969, Volume: 169, Issue:1

    Topics: Animals; Carbon Dioxide; Dogs; Escherichia coli; Hemodynamics; Oxygen; Polysaccharides, Bacterial; P

1969
[Renal blood flow in endotoxin shock].
    Masui. The Japanese journal of anesthesiology, 1970, Volume: 19, Issue:7

    Topics: Animals; Dogs; Hydrocortisone; Isoproterenol; Kidney; Norepinephrine; Phentolamine; Propranolol; Reg

1970
[The use of sympathomimetics and sympatholytics in shock].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:4

    Topics: Chlorpromazine; Dopamine; Humans; Isoproterenol; Metaraminol; Norepinephrine; Phenoxybenzamine; Phen

1971
The effect of adrenergic blockade upon shock-induced lacticacidosis in sheep.
    The British journal of surgery, 1968, Volume: 55, Issue:10

    Topics: Acidosis; Animals; Blood Pressure; Epinephrine; Female; Lactates; Male; Phenoxybenzamine; Propranolo

1968