propranolol has been researched along with Serotonin Syndrome in 5 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with propranolol (10 mg/kg), a 5-HT(1A) receptor antagonist as well as a beta-blocker, and dantrolene (20 mg/kg), a peripheral muscle relaxant, did not prevent the death of the animals, even though these two drugs suppressed the increase in rectal temperature to some extent." | 1.31 | Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome. ( Katoh, S; Nisijima, K; Yoshino, T; Yui, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ronan, GP | 1 |
| Ronan, N | 1 |
| McGettigan, S | 1 |
| Browne, G | 1 |
| Dimellis, D | 1 |
| Mahajan, R | 1 |
| Gupta, R | 1 |
| Sharma, A | 1 |
| Darmani, NA | 1 |
| Zhao, W | 1 |
| Nisijima, K | 1 |
| Yoshino, T | 1 |
| Yui, K | 1 |
| Katoh, S | 1 |
5 other studies available for propranolol and Serotonin Syndrome
| Article | Year |
|---|---|
Serotonin syndrome unmasking thyrotoxicosis.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Aftercare; Anti-Arrhythmia Agents; Antithyroid Agents; Carbima | 2019 |
Serotonin syndrome produced by a combination of venlafaxine and mirtazapine.
Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Tricyclic; Cyclohexanols; Drug Therapy, C | 2002 |
Management of serotonin syndrome.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Nitroprusside; Prognosis; Pr | 2005 |
Production of serotonin syndrome by 8-OH DPAT in Cryptotis parva.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Dose-Response Relation | 1998 |
Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome.
Topics: 5-Hydroxytryptophan; Animals; Anterior Hypothalamic Nucleus; Antidepressive Agents; Body Temperature | 2001 |