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propranolol and Response Evaluation Criteria in Solid Tumors

propranolol has been researched along with Response Evaluation Criteria in Solid Tumors in 1 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Response Evaluation Criteria in Solid Tumors: An internationally recognized set of published rules used for evaluation of cancer treatment that define when tumors found in cancer patients improve, worsen, or remain stable during treatment. These criteria are based specifically on the response of the tumor(s) to treatment, and not on the overall health status of the patient resulting from treatment.

Research Excerpts

ExcerptRelevanceReference
" Here, we report the results of dose escalation of a nonselective β-blocker (propranolol) with pembrolizumab in patients with metastatic melanoma."9.41Phase I Clinical Trial of Combination Propranolol and Pembrolizumab in Locally Advanced and Metastatic Melanoma: Safety, Tolerability, and Preliminary Evidence of Antitumor Activity. ( Allen, C; Attwood, K; Bucsek, MJ; Cedeno, CD; Drabick, JJ; Ernstoff, MS; Funchain, P; Gandhi, S; Ji, W; Knudsen, ES; Levis, M; Mohammadpour, H; Pandey, MR; Puzanov, I; Repasky, EA; Stack, S; Tario, JD; Wallace, PK; Witkiewicz, AK, 2021)
" Here, we report the results of dose escalation of a nonselective β-blocker (propranolol) with pembrolizumab in patients with metastatic melanoma."5.41Phase I Clinical Trial of Combination Propranolol and Pembrolizumab in Locally Advanced and Metastatic Melanoma: Safety, Tolerability, and Preliminary Evidence of Antitumor Activity. ( Allen, C; Attwood, K; Bucsek, MJ; Cedeno, CD; Drabick, JJ; Ernstoff, MS; Funchain, P; Gandhi, S; Ji, W; Knudsen, ES; Levis, M; Mohammadpour, H; Pandey, MR; Puzanov, I; Repasky, EA; Stack, S; Tario, JD; Wallace, PK; Witkiewicz, AK, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Gandhi, S1
Pandey, MR1
Attwood, K1
Ji, W1
Witkiewicz, AK1
Knudsen, ES1
Allen, C1
Tario, JD1
Wallace, PK1
Cedeno, CD1
Levis, M1
Stack, S1
Funchain, P1
Drabick, JJ1
Bucsek, MJ1
Puzanov, I1
Mohammadpour, H1
Repasky, EA1
Ernstoff, MS1

Trials

1 trial available for propranolol and Response Evaluation Criteria in Solid Tumors

ArticleYear
Phase I Clinical Trial of Combination Propranolol and Pembrolizumab in Locally Advanced and Metastatic Melanoma: Safety, Tolerability, and Preliminary Evidence of Antitumor Activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 01-01, Volume: 27, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined

2021