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propranolol and Reperfusion Injury

propranolol has been researched along with Reperfusion Injury in 15 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"A series of aminoalkanolic derivatives of xanthone with high affinity for β1-adrenoceptors was evaluated for antiarrhythmic activity in the model of ischemia-reperfusion in isolated hearts, as well as in barium chloride- and adrenaline-induced model of arrhythmia."3.80Antiarrhythmic activity of some xanthone derivatives with β1-adrenoceptor affinities in rats. ( Bednarski, M; Filipek, B; Marona, H; Rapacz, A; Sapa, J; Szkaradek, N, 2014)
"The present study was undertaken to explore the interaction of garlic homogenate (GH) with propranolol (PRO) on ischemia-reperfusion injury (IRI) in isolated rat heart preparation."3.76Pharmacodynamic interaction of garlic with propranolol in ischemia-reperfusion induced myocardial damage. ( Asad, M; Asdaq, SM; Inamdar, MN, 2010)
" At the end of treatment period, MI was induced by administering isoproterenol (ISO) or by subjecting heart to ischemia reperfusion injury (IRI)."3.75Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury. ( Asdaq, SM; Kubavat, JB, 2009)
" The present study was designed to examine the effects of hypoxia/reperfusion on the disposition of glutamate and propranolol in the rat isolated perfused liver."3.74Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver. ( Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS, 2007)
") reduced or completely abolished the ventricular fibrillation (VF) induced by reperfusion after 5 min of regional ischemia, while lidocaine, a class I antiarrhythmic agent, showed less effect against VF as compared with FR168888."3.70Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds. ( Goto, T; Maeda, K; Ohara, F; Ohkubo, K; Ozaki, T; Seki, J; Sugimoto, T; Yamamoto, N, 1999)
"Prazosin or yohimbine treatment did not significantly influence the NE+hypoxia effect."1.42Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries. ( Fähling, M; Gaestel, M; Hultström, M; Kaufmann, J; Liu, ZZ; Martinka, P; Moede, O; Moraes-Silva, IC; Nikitina, T; Patzak, A; Sendeski, M; Steege, A; Zavaritskaya, O, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (20.00)18.2507
2000's8 (53.33)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Assis de Brito, TL1
Monte-Alto-Costa, A1
Romana-Souza, B1
Rapacz, A1
Sapa, J1
Bednarski, M1
Filipek, B1
Szkaradek, N1
Marona, H1
Kaufmann, J1
Martinka, P1
Moede, O1
Sendeski, M1
Steege, A1
Fähling, M1
Hultström, M1
Gaestel, M1
Moraes-Silva, IC1
Nikitina, T1
Liu, ZZ1
Zavaritskaya, O1
Patzak, A1
Kubavat, JB1
Asdaq, SM2
Inamdar, MN1
Asad, M1
Fang, QJ1
Wang, YF1
Wang, RX1
Wu, ZJ1
He, RL1
Peng, XP1
Igarashi, N1
Nozawa, T1
Fujii, N1
Suzuki, T1
Matsuki, A1
Nakadate, T1
Igawa, A1
Inoue, H1
Arab, HA1
Cheung, K1
Hickman, PE1
Potter, JM1
Kadkhodaee, M1
Roberts, MS1
Bhatt, LK1
Nandakumar, K1
Bodhankar, SL1
Bansal, J1
Piplani, P1
Zhang, YM1
Wei, EQ1
Hu, X1
Xu, M1
Shi, Y1
Zhang, JF1
Ohara, F1
Sugimoto, T1
Yamamoto, N1
Ohkubo, K1
Ozaki, T1
Maeda, K1
Seki, J1
Goto, T1
Börjesson, A1
Norlin, A1
Wang, X1
Andersson, R1
Folkesson, HG1
Horio, T1
Ito, S1
Aoyama, M1
Takeda, Y1
Suzumura, H1
Nakata, K1
Yamada, Y1
Suzuki, S1
Fukutomi, T1
Itoh, M1
Liu, XK1
Engelman, RM1
Agrawal, HR1
Das, DK1
Mouton, R1
Huisamen, B1
Lochner, A1

Other Studies

15 other studies available for propranolol and Reperfusion Injury

ArticleYear
Propranolol impairs the closure of pressure ulcers in mice.
    Life sciences, 2014, Apr-01, Volume: 100, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blotting, Western; Epidermis; Hydroxyproline; Immunoenzyme Tec

2014
Antiarrhythmic activity of some xanthone derivatives with β1-adrenoceptor affinities in rats.
    European journal of pharmacology, 2014, Sep-05, Volume: 738

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Atenolol; Barium Compounds; Chl

2014
Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries.
    Acta physiologica (Oxford, England), 2015, Volume: 213, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-An

2015
Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury.
    Journal of ethnopharmacology, 2009, Jul-06, Volume: 124, Issue:1

    Topics: Animals; Antioxidants; Catalase; Creatine Kinase, MB Form; Heart; Isoproterenol; L-Lactate Dehydroge

2009
Pharmacodynamic interaction of garlic with propranolol in ischemia-reperfusion induced myocardial damage.
    Pakistan journal of pharmaceutical sciences, 2010, Volume: 23, Issue:1

    Topics: Animals; Antioxidants; Cardiotonic Agents; Creatine Kinase, MB Form; Dose-Response Relationship, Dru

2010
[The effect of different dose of verapamil and propranolol in kalium cardioplegia on the function of immature rat heart].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:2

    Topics: Animals; Cardioplegic Solutions; Female; Heart; In Vitro Techniques; Male; Myocardium; Propranolol;

2008
Influence of beta-adrenoceptor blockade on the myocardial accumulation of fatty acid tracer and its intracellular metabolism in the heart after ischemia-reperfusion injury.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Autoradiography; Carbazoles; Carvedilol; Fatty Acids; Iodobenz

2006
Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Aspartate Aminotransferases; Carbon Dioxide; Carbon Radioisoto

2007
Beta-blocking activity of PP-34, a newly synthesized aryloxypropanolamine derivative, and its cardioprotective effect against ischaemia/reperfusion injury in laboratory animals.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Atenolol; Benzylamines; Female; Guinea P

2007
Administration of angiotensin II in the paraventricular nucleus protects gastric mucosa from ischemia-reperfusion injury.
    Brain research, 2008, May-30, Volume: 1212

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease M

2008
Protective effect of FR168888, a new Na+/H+ exchange inhibitor, on ischemia and reperfusion-induced arrhythmia and myocardial infarction in rats: in comparison with other cardioprotective compounds.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:4

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzyl Alcohol; Benzyl Alcohols; Diltiazem; Dose-Response

1999
TNF-alpha stimulates alveolar liquid clearance during intestinal ischemia-reperfusion in rats.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:1

    Topics: Adrenergic beta-Antagonists; Amiloride; Animals; Antibodies, Monoclonal; Body Water; Capillary Perme

2000
Effect of carvedilol on atrioventricular conduction in the ischemic heart.
    European journal of pharmacology, 2001, Jan-26, Volume: 412, Issue:2

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Bundle of His

2001
Preservation of membrane phospholipids by propranolol, pindolol, and metoprolol: a novel mechanism of action of beta-blockers.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Fatty

1991
Increased myocardial inositol trisphosphate levels during alpha 1-adrenergic stimulation and reperfusion of ischaemic rat heart.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:7

    Topics: Adrenergic Fibers; Animals; Atropine; Coronary Disease; Heart; Inositol; Male; Myocardial Contractio

1991