propranolol has been researched along with Renal Insufficiency in 4 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the mechanism responsible for the increased bioavailability of propranolol in bilateral ureter-ligated (BUL) rats, the intestinal absorption and hepatic extraction of propranolol and metoprolol were evaluated." | 1.32 | Intestinal absorption and hepatic extraction of propranolol and metoprolol in rats with bilateral ureteral ligation. ( Hashimoto, Y; Higashi, T; Ohta, T; Okabe, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sersté, T | 1 |
| Melot, C | 1 |
| Francoz, C | 1 |
| Durand, F | 1 |
| Rautou, PE | 1 |
| Valla, D | 1 |
| Moreau, R | 1 |
| Lebrec, D | 1 |
| Efe, C | 1 |
| Purnak, T | 1 |
| Ozaslan, E | 1 |
| Wong, F | 1 |
| Salerno, F | 1 |
| Okabe, H | 1 |
| Higashi, T | 1 |
| Ohta, T | 1 |
| Hashimoto, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Preoperative Beta Blocker Use on Intraoperative Hemodynamics and Postoperative Renal Function in End-stage Liver Disease Patients Undergoing Liver Transplantation[NCT03633812] | 477 participants (Anticipated) | Observational [Patient Registry] | 2016-10-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for propranolol and Renal Insufficiency
| Article | Year |
|---|---|
Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites.
Topics: Adrenergic beta-Antagonists; Aged; Ascites; Contraindications; Female; Follow-Up Studies; Humans; Hy | 2010 |
The deleterious effects of propranolol on patients with cirrhosis.
Topics: Cardiac Output; Humans; Hyponatremia; Liver Cirrhosis; Propranolol; Renal Insufficiency | 2011 |
Beta-blockers in cirrhosis: friend and foe?
Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Humans; Liver Cirrhosis; Peritonitis; P | 2010 |
Intestinal absorption and hepatic extraction of propranolol and metoprolol in rats with bilateral ureteral ligation.
Topics: Adrenergic beta-Antagonists; Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Glucok | 2004 |