Page last updated: 2024-11-03

propranolol and Pulmonary Hypertension

propranolol has been researched along with Pulmonary Hypertension in 28 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"We determined whether milrinone, a phosphodiesterase III inhibitor, attenuates serotonin-induced (5-hydroxytryptamine [5HT]) pulmonary hypertension (PH) and bronchoconstriction."7.70Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs. ( Hashiba, E; Hashimoto, Y; Hirota, K; Kudo, T; Matsuki, A; Sato, T; Yoshioka, H, 2000)
"In the present study in dogs, we compared with aminophylline the spasmolytic effects of olprinone, a novel phosphodiesterase 3 inhibitor, on serotonin-induced pulmonary hypertension (PH) and bronchoconstriction."7.70A comparison of the spasmolytic effects of olprinone and aminophylline on serotonin-induced pulmonary hypertension and bronchoconstriction with or without beta-blockade in dogs. ( Hashimoto, Y; Hirota, K; Ishihara, H; Kudo, T; Matsuki, A; Yoshioka, H, 2000)
"Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13."7.65Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975)
"Detailed examination of hemodynamics in patients with portal and pulmonary hypertension was performed upon acute drug tests and course administration of nitrosorbide++, corinfar and propranolol."5.07[Drug therapy of pulmonary and portal hypertension in liver cirrhosis]. ( Andreev, NG; Maev, IV; Vorob'ev, LP, 1991)
"The study consisted of six groups (N=30; five rabbits/group): (1) Control with no pretreatment, monocrotaline injected groups: (solutions were perfused following termination of CPB for 60 min); (2) Control for pulmonary hypertension (PHT); (3) isoproteronol; (4) VIP 10(-6) M; (5) VIP 10(-5) M; (6) nitroglycerine."3.71The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine. ( Chang, D; Gunaydin, S; Hagino, I; Imai, Y; Seo, K; Shinoka, T; Takanashi, Y, 2002)
"We determined whether milrinone, a phosphodiesterase III inhibitor, attenuates serotonin-induced (5-hydroxytryptamine [5HT]) pulmonary hypertension (PH) and bronchoconstriction."3.70Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs. ( Hashiba, E; Hashimoto, Y; Hirota, K; Kudo, T; Matsuki, A; Sato, T; Yoshioka, H, 2000)
"In the present study in dogs, we compared with aminophylline the spasmolytic effects of olprinone, a novel phosphodiesterase 3 inhibitor, on serotonin-induced pulmonary hypertension (PH) and bronchoconstriction."3.70A comparison of the spasmolytic effects of olprinone and aminophylline on serotonin-induced pulmonary hypertension and bronchoconstriction with or without beta-blockade in dogs. ( Hashimoto, Y; Hirota, K; Ishihara, H; Kudo, T; Matsuki, A; Yoshioka, H, 2000)
"Hypoxia causes the release of atrial natriuretic factor (ANF), but the mechanisms are not yet understood."3.68Neural control of ANF release in hypoxia and pulmonary hypertension. ( Baertschi, AJ; Campbell, RW; Carlson, DE; Gann, DS; Jiao, JH; Teague, WG; Willson, D, 1990)
"Thirteen patients with severe hypertension were treated with combined minoxidil, propranolol, and furosemide (mean daily doses 33 mg, 475 mg, and 578 mg, respectively) for nine to twenty-five months (mean 13."3.65Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide. ( Bennet, CM; Blaufuss, A; Wilburn, RL, 1975)
"Pretreatment with methysergide, a serotonin antagonist, partially attenuated the effects of CuSO4."1.26Acute pulmonary hemodynamic effects of intravenous copper sulfate: role of alpha-adrenergic system. ( Ahmed, T; Eyre, P; Januszkiewicz, A; Robinson, MJ; Sackner, MA, 1981)
"4 sec; long-term administration av."1.26Hemodynamic effects of beta-adrenergic blockade with pindolol, oxprenolol, propranolol and bufetolol hydrochloride in essential hypertension. ( Hashimoto, M; Miyamoto, K; Otsuka, K; Tsukiyama, H; Yasutake, S, 1976)
"We advocate the use of propranolol in very low dosage at the end of operation to determine a prognosis of the long-term results to be expected after valvulotomy in diverse types of pulmonary stenosis."1.26The postvalvulotomy propranolol test to determine reversibility of the residual gradient in pulmonary stenosis. ( Buis-Liem, TN; Geldof, WC; Moulaert, AJ; Rohmer, J, 1976)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's5 (17.86)18.2507
2000's7 (25.00)29.6817
2010's3 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hung, YM1
Cheng, CC1
Wann, SR1
Lin, SL1
Diong, C1
Jones, PP1
Tsuchimochi, H2
Gray, EA1
Hughes, G1
Inagaki, T1
Bussey, CT1
Fujii, Y1
Umetani, K2
Shirai, M2
Schwenke, DO2
Pearson, JT1
Shimochi, A1
Kangawa, K1
Cragg, PA1
Kamalanathan, S1
Balachandran, K1
Packirisamy, G1
Hamide, A1
Brimioulle, S1
Wauthy, P1
Ewalenko, P1
Rondelet, B1
Vermeulen, F1
Kerbaul, F1
Naeije, R1
TSOLAKAS, TC1
DAVIES, JP1
ORAM, S1
Okada, Y1
Hoshikawa, Y1
Ejima, Y1
Matsumura, Y1
Sado, T1
Shimada, K1
Aikawa, H1
Sugawara, T1
Matsuda, Y1
Takahashi, T1
Sato, M1
Kondo, T1
Wasseem, R1
Mazen, E1
Walid, SR1
Ahmed, T1
Januszkiewicz, A1
Eyre, P1
Robinson, MJ1
Sackner, MA1
Galinier, M1
Rougé, P1
Fourcade, J1
Senard, JM1
Albenque, JP1
Balanescu, S1
Doazan, JP1
Montastruc, JL1
Bounhoure, JP1
Montastruc, P1
Buchhorn, R1
Hulpke-Wette, M1
Wessel, A1
Bürsch, J1
Hashiba, E1
Hirota, K2
Yoshioka, H2
Hashimoto, Y2
Kudo, T2
Sato, T1
Matsuki, A2
Ishihara, H1
Gunaydin, S1
Imai, Y1
Takanashi, Y1
Seo, K1
Hagino, I1
Chang, D1
Shinoka, T1
Tsukiyama, H1
Otsuka, K1
Miyamoto, K1
Hashimoto, M1
Yasutake, S1
Moulaert, AJ1
Buis-Liem, TN1
Geldof, WC1
Rohmer, J1
Moret, PR1
Duchosal, F1
von Wichert, P1
Khamzamulin, RO1
Mirrakhimov, MM1
Brimkulov, NN1
Kaliuzhnyĭ, SI1
Wilburn, RL1
Blaufuss, A1
Bennet, CM1
Maev, IV3
Vorob'ev, LP3
Kaziulin, AN1
Andreev, NG1
Baertschi, AJ1
Jiao, JH1
Carlson, DE1
Campbell, RW1
Teague, WG1
Willson, D1
Gann, DS1
Sun, RY1
Völkel, N1
Siemssen, S1
Kaukel, E1
Sill, V1
Vogel, JH1
Chidsey, CA1
Mielke, H1
Seiler, KU1
Stumpf, U1
Wassermann, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Untersuchung Des Einflusses PAH-spezifischer Medikation Auf Die rechtsventrikuläre Funktion Bei Patienten Mit Pulmonaler Arterieller Hypertonie (PAH) Unter Basalen Bedingungen[NCT03362047]Phase 230 participants (Anticipated)Interventional2018-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for propranolol and Pulmonary Hypertension

ArticleYear
[Drug therapy of pulmonary and portal hypertension in liver cirrhosis].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension, Portal; Hypertension, Pulmonary; Isosorb

1991

Other Studies

27 other studies available for propranolol and Pulmonary Hypertension

ArticleYear
Ankylosing spondylitis associated with pulmonary arterial hypertension.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:4

    Topics: Adult; Antihypertensive Agents; Heart Atria; Humans; Hypertension, Pulmonary; Male; Propranolol; Spo

2015
Sympathetic hyper-excitation in obesity and pulmonary hypertension: physiological relevance to the 'obesity paradox'.
    International journal of obesity (2005), 2016, Volume: 40, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung

2016
Changes in pulmonary blood flow distribution in monocrotaline compared with hypoxia-induced models of pulmonary hypertension: assessed using synchrotron radiation.
    Journal of hypertension, 2009, Volume: 27, Issue:7

    Topics: Adrenergic beta-Antagonists; Angiography; Animals; Disease Models, Animal; Hypertension, Pulmonary;

2009
Graves' disease--familiar foe, unfamiliar face.
    BMJ case reports, 2012, Aug-01, Volume: 2012

    Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Antithyroid Agents; Atrial Fibrillation; Car

2012
Single-beat estimation of right ventricular end-systolic pressure-volume relationship.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:5

    Topics: Animals; Cardiotonic Agents; Dobutamine; Dogs; Hypertension, Pulmonary; Myocardial Contraction; Pred

2003
EFFECT OF A BETA-ADRENERGIC-BLOCKING AGENT ON THELATION IN MITRAL STENOSIS.
    Lancet (London, England), 1965, Aug-28, Volume: 2, Issue:7409

    Topics: Adrenergic Antagonists; Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiac Output; Heart

1965
Beta-blocker prevented repeated pulmonary hypertension episodes after bilateral lung transplantation in a patient with primary pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 2004, Volume: 128, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Transplantat

2004
Hyperthyroidism: a rare cause of reversible pulmonary hypertension.
    The American journal of the medical sciences, 2006, Volume: 332, Issue:3

    Topics: Antihypertensive Agents; Antithyroid Agents; Female; Humans; Hypertension, Pulmonary; Hyperthyroidis

2006
Acute pulmonary hemodynamic effects of intravenous copper sulfate: role of alpha-adrenergic system.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1981, Volume: 51, Issue:5

    Topics: Animals; Chlorpheniramine; Copper; Copper Sulfate; Female; Hydroxydopamines; Hypertension, Pulmonary

1981
Lack of haemodynamic effects of nitric oxide on post-capillary pulmonary hypertension induced by acute sino-aortic denervation.
    British journal of pharmacology, 1997, Volume: 120, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Denervation; Dogs; Enzyme Inhibitors; Hemodynamics; Hypertensi

1997
Beta-blocker therapy in an infant with pulmonary hypertension.
    European journal of pediatrics, 1999, Volume: 158, Issue:12

    Topics: Adrenergic beta-Antagonists; Humans; Hypertension, Pulmonary; Infant; Norepinephrine; Propranolol

1999
Milrinone attenuates serotonin-induced pulmonary hypertension and bronchoconstriction in dogs.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:4

    Topics: Animals; Bronchoconstriction; Catecholamines; Dogs; Hypertension, Pulmonary; Milrinone; Phosphodiest

2000
A comparison of the spasmolytic effects of olprinone and aminophylline on serotonin-induced pulmonary hypertension and bronchoconstriction with or without beta-blockade in dogs.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:6

    Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Bronchoconstriction; Bronchodilator Agents; Dog

2000
The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine.
    Cardiovascular surgery (London, England), 2002, Volume: 10, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Cardiopulm

2002
Hemodynamic effects of beta-adrenergic blockade with pindolol, oxprenolol, propranolol and bufetolol hydrochloride in essential hypertension.
    Japanese circulation journal, 1976, Volume: 40, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Circulation; Blood Pressure; Cardiac Output; Female;

1976
The postvalvulotomy propranolol test to determine reversibility of the residual gradient in pulmonary stenosis.
    The Journal of thoracic and cardiovascular surgery, 1976, Volume: 71, Issue:6

    Topics: Cardiac Catheterization; Cardiomegaly; Child; Child, Preschool; Electrocardiography; Humans; Hyperte

1976
[Effects of propranolol on pulmonary hypertension, right ventricular hypertrophy and metabolic myocardial changes due to acute hypoxemia due to high altitude].
    Schweizerische medizinische Wochenschrift, 1976, Nov-06, Volume: 106, Issue:45

    Topics: Altitude; Animals; Cardiomegaly; Energy Metabolism; Hypertension, Pulmonary; Male; Myocardium; Propr

1976
[Drug side-effects in the lung].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-10, Volume: 103, Issue:6

    Topics: Antineoplastic Agents; Asthma; Carbamazepine; Cromolyn Sodium; Drug-Related Side Effects and Adverse

1978
[Effect of obsidan on the cardiovascular system under conditions of high-altitude hypoxia].
    Kardiologiia, 1978, Volume: 18, Issue:10

    Topics: Adaptation, Physiological; Adult; Altitude; Blood Pressure; Cerebrovascular Circulation; Hemodynamic

1978
Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
    Circulation, 1975, Volume: 52, Issue:4

    Topics: Cardiac Catheterization; Drug Therapy, Combination; Echocardiography; Edema; Furosemide; Humans; Hyd

1975
[Pulmonary hemodynamics in patients with hypertension during acute drug tests using obsidan and corinfar].
    Kardiologiia, 1991, Volume: 31, Issue:3

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Male; Middle Aged; Nifed

1991
Neural control of ANF release in hypoxia and pulmonary hypertension.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2

    Topics: Animals; Atrial Natriuretic Factor; Female; Hypertension, Pulmonary; Hypoxia; Male; Nervous System;

1990
[Use of beta blockaders in pulmonary hypertension in patients with liver diseases].
    Sovetskaia meditsina, 1989, Issue:12

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Drug Evaluation; Hepatitis, Chronic; Humans; H

1989
[Effect of propranolol on attenuation of rat hypoxic pulmonary hypertension due to radix angelicae sinensis].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1988, Volume: 10, Issue:5

    Topics: Animals; Drugs, Chinese Herbal; Hypertension, Pulmonary; Hypoxia; Male; Propranolol; Rats; Rats, Inb

1988
[Significance of the beta-receptor system for the Euler-Liljestrand mechanism].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Adrenergic beta-Antagonists; Aminophylline; Animals; Calcium; Cyclic AMP; Hypertension, Pulmonary; H

1974
Cardiac adrenergic activity in experimental heart failure assessed with beta receptor blockade.
    The American journal of cardiology, 1969, Volume: 24, Issue:2

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Cardiomegaly; Cattle; Epinephrine; Heart; H

1969
[Relation between serotonin metabolism and pulmonary hypertension in rats following administration of various anorectic drugs].
    Zeitschrift fur Kardiologie, 1973, Volume: 62, Issue:12

    Topics: Amines; Amphetamine; Animals; Appetite Depressants; Chlorphentermine; Hypertension, Pulmonary; Male;

1973