propranolol has been researched along with Psychomotor Agitation in 55 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although several reports suggest that intermediate to high doses of propranolol (80-160 and 200-600 mg/day) can effectively treat aggressive behavior in dementia, significant side effects can occur at these doses." | 7.69 | Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. ( Cotman, CW; Nielson, KA; Shankle, WR, 1995) |
| " Furthermore, this case suggests that changing the regimen to aripiprazole with propranolol may be a potential option for amisulpride withdrawal akathisia superimposed on pre-existing hyperprolactinemia." | 4.12 | Amisulpride withdrawal akathisia responding to aripiprazole with propranolol in first-onset psychosis: a case report. ( Kim, SG; Seo, EH; Yang, HJ; Yoon, HJ, 2022) |
| "Although several reports suggest that intermediate to high doses of propranolol (80-160 and 200-600 mg/day) can effectively treat aggressive behavior in dementia, significant side effects can occur at these doses." | 3.69 | Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients. ( Cotman, CW; Nielson, KA; Shankle, WR, 1995) |
| "Suicidal ideation was significantly associated with clinician observed akathisia, depressed mood, younger age, and use of propranolol." | 2.77 | Akathisia and suicidal ideation in first-episode schizophrenia. ( Gaebel, W; Gastpar, M; Heuser, I; Jäger, M; Klingenberg, S; Klosterkötter, J; Lewitzka, U; Maier, W; Mayr, A; Möller, HJ; Musil, R; Ohmann, C; Riedel, M; Schennach, R; Schlösser, R; Schmitt, A; Schneider, F; Seemüller, F, 2012) |
| "Antipsychotic-induced akathisia is optimally managed by reducing the medication dose or switching to a second generation antipsychotic that is less prone to inducing akathisia." | 2.72 | Struggling to find Effective Pharmacologic Options for Akathisia? B-CALM! ( Birur, B; Fargason, RE; Thippaiah, SM, 2021) |
| "Surprisingly, the evidence for its anti-akathisia effect is modest." | 2.66 | Treatment of Antipsychotic-Induced Akathisia: Role of Serotonin 5-HT ( Poyurovsky, M; Weizman, A, 2020) |
| "At the ED, she presented an episode of presyncope followed by agitation." | 1.48 | Dangerous mistake: an accidental caffeine overdose. ( Andrade, A; Fernandes, M; Pedro, M; Sousa, C, 2018) |
| "He developed akathisia on 44th day of admission as a relapse and he was successfully treated with propranolol." | 1.40 | Akathisia in association with herpes simplex encephalitis relapse and opercular syndrome in children. ( Ekici, A; Kocak, O; Saylisoy, S; Yakut, A; Yarar, C; Yimenicioglu, S, 2014) |
| "As a result, SSRIinduced akathisia is very frequently under-recognized." | 1.40 | A case of akathisia induced by escitalopram: case report & review of literature. ( Basu, B; De, S; Dutta, N; Gangopadhyay, T; Mandal, B; Mondal, S, 2014) |
| "Pretreatment with propranolol (5 mg/kg) reduced the number of Fos-positive nuclei in the cingulate cortex area 3, the piriform cortex and area 1 of the parietal cortex." | 1.30 | Propranolol attenuates haloperidol-induced Fos expression in discrete regions of rat brain: possible brain regions responsible for akathisia. ( Fujiwara, Y; Hamamura, T; Kuroda, S; Lee, Y; Ohashi, K, 1998) |
| "Akathisia improved in 4 patients with idiopathic Parkinson's disease after low dose propranolol treatment." | 1.28 | Studies on the time course and efficacy of beta-blockers in neuroleptic-induced akathisia and the akathisia of idiopathic Parkinson's disease. ( Adler, LA; Angrist, B; Rotrosen, J; Weinreb, H, 1991) |
| "All three patients developed severe akathisia during retreatment with fluoxetine and stated that the development of the akathisia made them feel suicidal and that it had precipitated their prior suicide attempts." | 1.28 | Reexposure to fluoxetine after serious suicide attempts by three patients: the role of akathisia. ( Locke, CA; Rothschild, AJ, 1991) |
| "Metoprolol was compared to propranolol in the treatment of neuroleptic-induced akathisia by means of an on-drug/off-drug crossover study." | 1.27 | Comparison of metoprolol and propranolol in the treatment of akathisia. ( Barreira, PJ; Cohen, BM; Lipinski, JF; Zubenko, GS, 1984) |
| "Propranolol was found to be an effective treatment of tardive akathisia in both patients." | 1.27 | Propranolol in the treatment of tardive akathisia: a report of two cases. ( Iskandar, H; Nastase, C; Yassa, R, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (52.73) | 18.7374 |
| 1990's | 14 (25.45) | 18.2507 |
| 2000's | 4 (7.27) | 29.6817 |
| 2010's | 5 (9.09) | 24.3611 |
| 2020's | 3 (5.45) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, HJ | 1 |
| Kim, SG | 1 |
| Seo, EH | 1 |
| Yoon, HJ | 1 |
| Poyurovsky, M | 1 |
| Weizman, A | 1 |
| Thippaiah, SM | 1 |
| Fargason, RE | 1 |
| Birur, B | 1 |
| Andrade, A | 1 |
| Sousa, C | 1 |
| Pedro, M | 1 |
| Fernandes, M | 1 |
| Luján, MA | 1 |
| Colomar, L | 1 |
| Tarragón, E | 1 |
| López-Cruz, L | 1 |
| Pastor, R | 1 |
| Font, L | 1 |
| Kocak, O | 1 |
| Yarar, C | 1 |
| Yakut, A | 1 |
| Ekici, A | 1 |
| Yimenicioglu, S | 1 |
| Saylisoy, S | 1 |
| Basu, B | 1 |
| Gangopadhyay, T | 1 |
| Dutta, N | 1 |
| Mandal, B | 1 |
| De, S | 1 |
| Mondal, S | 1 |
| Seemüller, F | 1 |
| Schennach, R | 1 |
| Mayr, A | 1 |
| Musil, R | 1 |
| Jäger, M | 1 |
| Maier, W | 1 |
| Klingenberg, S | 1 |
| Heuser, I | 1 |
| Klosterkötter, J | 1 |
| Gastpar, M | 1 |
| Schmitt, A | 1 |
| Schlösser, R | 1 |
| Schneider, F | 1 |
| Ohmann, C | 1 |
| Lewitzka, U | 1 |
| Gaebel, W | 1 |
| Möller, HJ | 1 |
| Riedel, M | 1 |
| Vanderschuren, LJ | 1 |
| Beemster, P | 1 |
| Schoffelmeer, AN | 1 |
| Summers, WK | 1 |
| Fleminger, S | 1 |
| Greenwood, RJ | 1 |
| Oliver, DL | 1 |
| Petrie, WM | 1 |
| Ban, TA | 1 |
| Kulik, AV | 2 |
| Wilbur, R | 2 |
| Lipinski, JF | 4 |
| Zubenko, GS | 2 |
| Cohen, BM | 2 |
| Barreira, PJ | 2 |
| Shankle, WR | 1 |
| Nielson, KA | 1 |
| Cotman, CW | 1 |
| Ohashi, K | 1 |
| Hamamura, T | 1 |
| Lee, Y | 1 |
| Fujiwara, Y | 1 |
| Kuroda, S | 1 |
| Tariot, PN | 1 |
| Poindexter, AR | 1 |
| Schreier, HA | 1 |
| Dumon, JP | 2 |
| Catteau, J | 2 |
| Lanvin, F | 1 |
| Dupuis, BA | 1 |
| Brooke, MM | 1 |
| Patterson, DR | 1 |
| Questad, KA | 1 |
| Cardenas, D | 1 |
| Farrel-Roberts, L | 1 |
| Adler, LA | 5 |
| Angrist, B | 11 |
| Fritz, P | 1 |
| Rotrosen, J | 11 |
| Mallya, G | 1 |
| Weinreb, H | 1 |
| Rothschild, AJ | 1 |
| Locke, CA | 1 |
| Fleischhacker, WW | 1 |
| Sachdev, P | 1 |
| Chee, KY | 1 |
| Pauszek, ME | 1 |
| Rosenthal, S | 1 |
| Ellison, J | 1 |
| Chandler, JD | 1 |
| Adler, L | 6 |
| Duncan, E | 1 |
| Hemdal, P | 1 |
| Slotnick, V | 1 |
| Eimer, M | 1 |
| Kim, A | 1 |
| Kramer, MS | 2 |
| Gorkin, R | 1 |
| DiJohnson, C | 2 |
| Peselow, E | 3 |
| Corwin, J | 5 |
| Haas, JF | 1 |
| Cope, DN | 1 |
| Keepers, GA | 1 |
| Casey, DE | 1 |
| Maslansky, R | 1 |
| Dupuis, B | 1 |
| Libert, C | 1 |
| Petit, H | 1 |
| Reiter, S | 3 |
| Herndal, P | 1 |
| Hermesh, H | 1 |
| Molcho, A | 1 |
| Munitz, H | 1 |
| Yassa, R | 1 |
| Iskandar, H | 1 |
| Nastase, C | 1 |
| Irwin, M | 1 |
| Sullivan, G | 1 |
| Van Putten, T | 1 |
| Gorkin, RA | 1 |
| Sheves, P | 1 |
| Wang, HL | 1 |
| Keck, PE | 1 |
| McElroy, SL | 1 |
| Cerri, C | 1 |
| Cocco, E | 1 |
| Rovati, L | 1 |
| Roehrich, H | 1 |
| Gold, MS | 1 |
| Ellison, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maintenance Treatment vs. Stepwise Drug Discontinuation After One Year of Maintenance Treatment in First-Episode Schizophrenia[NCT00159120] | Phase 4 | 71 participants (Anticipated) | Interventional | 2001-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for propranolol and Psychomotor Agitation
| Article | Year |
|---|---|
Treatment of Antipsychotic-Induced Akathisia: Role of Serotonin 5-HT
Topics: Akathisia, Drug-Induced; Algorithms; Antipsychotic Agents; Humans; Propranolol; Psychomotor Agitatio | 2020 |
Struggling to find Effective Pharmacologic Options for Akathisia? B-CALM!
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Mirtazapine; Propranolol; Psychomotor Agitati | 2021 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2006 |
Treatment of agitation in dementia.
Topics: Caregivers; Confusion; Decision Trees; Dementia; Electroconvulsive Therapy; Estrogens; Humans; Lithi | 1999 |
Management of the behavioral symptoms associated with dementia.
Topics: Aged; Aggression; Antipsychotic Agents; Dementia; Humans; Pindolol; Propranolol; Psychomotor Agitati | 1989 |
Clinical management of acute neuroleptic-induced extrapyramidal syndromes.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Akathisia, Drug-Induced; Amantadine; Antipsychotic Ag | 1986 |
Beta-adrenergic antagonists in psychosis: is improvement due to treatment of neuroleptic-induced akathisia?
Topics: Adrenergic beta-Agonists; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; D | 1988 |
15 trials available for propranolol and Psychomotor Agitation
| Article | Year |
|---|---|
Akathisia and suicidal ideation in first-episode schizophrenia.
Topics: Adult; Age Factors; Akathisia, Drug-Induced; Antipsychotic Agents; Depression; Double-Blind Method; | 2012 |
Randomized, double-blind, crossover, placebo-controlled comparison of propranolol and betaxolol in the treatment of neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Betaxolol; Double-Blind Method; Humans; Middle | 1992 |
The treatment of agitation during initial hospitalization after traumatic brain injury.
Topics: Aggression; Brain Injuries; Humans; Propranolol; Psychomotor Agitation; Restraint, Physical | 1992 |
Lack of efficacy of d-propranolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Blood Pressure; Double-Blind Method; Female; H | 1991 |
Pharmacological characterization of tardive akathisia.
Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztr | 1990 |
Effects of a specific beta 2-receptor blocker in neuroleptic-induced akathisia.
Topics: Adrenergic beta-Antagonists; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; | 1989 |
Treatment of neuroleptic-induced akathisia with propranolol: a controlled replication study.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Benztropine; Dose-Response Relationship, Drug; Double | 1989 |
Efficacy of propranolol in neuroleptic-induced akathesia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Female; Humans; Lorazepam; Ma | 1985 |
A controlled assessment of propranolol in the treatment of neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; | 1986 |
Comparison of propranolol, sotalol, and betaxolol in the treatment of neuroleptic-induced akathisia.
Topics: Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Betaxolol; Clinical Trials as Topic; Dos | 1987 |
Noradrenergic mechanisms in akathisia: treatment with propranolol and clonidine.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clonidine; Female; Humans; Male; Middle Aged; | 1987 |
Atenolol and propranolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Atenolol; Female; Humans; Male; Middle Aged; P | 1987 |
Propranolol as a primary treatment of neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; | 1988 |
Propranolol in the treatment of neuroleptic-induced akathisia (NIA) in schizophrenics: a double-blind, placebo-controlled study.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Double-Blind Method; Humans; Male; Mi | 1988 |
Beta-adrenergic antagonists in psychosis: is improvement due to treatment of neuroleptic-induced akathisia?
Topics: Adrenergic beta-Agonists; Akathisia, Drug-Induced; Antipsychotic Agents; Clinical Trials as Topic; D | 1988 |
34 other studies available for propranolol and Psychomotor Agitation
| Article | Year |
|---|---|
Amisulpride withdrawal akathisia responding to aripiprazole with propranolol in first-onset psychosis: a case report.
Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benztropine; Female; Humans; Hyperprolactine | 2022 |
Dangerous mistake: an accidental caffeine overdose.
Topics: Acidosis; Administration, Intravenous; Adult; Aftercare; Anti-Arrhythmia Agents; Caffeine; Dietary S | 2018 |
Drug-free and context-dependent locomotor hyperactivity in DBA/2 J mice previously treated with repeated cocaine: Relationship with behavioral sensitization and role of noradrenergic receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Association; Behavior | 2019 |
Akathisia in association with herpes simplex encephalitis relapse and opercular syndrome in children.
Topics: Antiviral Agents; Child, Preschool; Encephalitis, Herpes Simplex; Epilepsy, Frontal Lobe; Humans; Ma | 2014 |
A case of akathisia induced by escitalopram: case report & review of literature.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Breast Neoplasms; Citalopram; | 2014 |
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Clonidine; Cocaine; Cocai | 2003 |
The management of agitation in demented patients with propranolol.
Topics: Aged; Antipsychotic Agents; Bronchial Spasm; Dementia; Disease Management; Humans; Male; Propranolol | 2006 |
Propranolol in organic agitation.
Topics: Aged; Dementia; Female; Humans; Male; Middle Aged; Propranolol; Psychomotor Agitation | 1981 |
Case report of propranolol (Inderal) pharmacotherapy for neuroleptic-induced akathisia and tremor.
Topics: Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Drug Therapy, Combination; Dyskinesia, Drug-Ind | 1983 |
Propranolol for akathisia.
Topics: Humans; Propranolol; Psychomotor Agitation | 1983 |
Propranolol in the treatment of neuroleptic-induced akathisia.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Bipolar Disorder; Female; Humans; | 1984 |
Comparison of metoprolol and propranolol in the treatment of akathisia.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Blood | 1984 |
Low-dose propranolol reduces aggression and agitation resembling that associated with orbitofrontal dysfunction in elderly demented patients.
Topics: Aged; Aggression; Alzheimer Disease; Dementia; Female; Humans; Male; Middle Aged; Propranolol; Psych | 1995 |
Propranolol attenuates haloperidol-induced Fos expression in discrete regions of rat brain: possible brain regions responsible for akathisia.
Topics: Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Brain; Brain Mapping; Drug Combinations; | 1998 |
Phenobarbital, propranolol, and aggression.
Topics: Aggression; Anti-Anxiety Agents; Anticonvulsants; Humans; Phenobarbital; Propranolol; Psychomotor Ag | 2000 |
Use of propranolol in the treatment of postencephalitic psychosis.
Topics: Child; Encephalitis; Humans; Male; Neurocognitive Disorders; Orientation; Propranolol; Psychomotor A | 1979 |
Studies on the time course and efficacy of beta-blockers in neuroleptic-induced akathisia and the akathisia of idiopathic Parkinson's disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Hum | 1991 |
Efficacy of betaxolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Betaxolol; Drug Administration Schedule; Human | 1991 |
Reexposure to fluoxetine after serious suicide attempts by three patients: the role of akathisia.
Topics: Adult; Akathisia, Drug-Induced; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; | 1991 |
Propanolol for fluoxetine-induced akathisia.
Topics: Akathisia, Drug-Induced; Depressive Disorder; Female; Fluoxetine; Humans; Middle Aged; Neurologic Ex | 1991 |
Propranolol for treatment of agitation in senile dementia.
Topics: Aged; Dementia; Humans; Male; Propranolol; Psychomotor Agitation | 1991 |
Propranolol withdrawal in psychosis.
Topics: Acute Disease; Adult; Female; Hallucinations; Humans; Propranolol; Psychomotor Agitation; Psychoses, | 1990 |
Propranolol treatment of akathesia in Tourette's syndrome.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Female; Humans; Propranolol; Psychiatric Statu | 1990 |
Efficacy of low-dose metoprolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Dose-Response Relationship, D | 1989 |
Neuropharmacologic management of behavior sequelae in head injury: a case report.
Topics: Adult; Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Behavior; Craniocerebral Trauma; Human | 1985 |
Pindolol and propranolol in neuroleptic-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Middle Aged; Pindolol; Propranolol; Ps | 1987 |
Neuroleptic-induced akathisia: propranolol versus benztropine.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Benztropine; Humans; Propranolol; Psychomotor Agitati | 1988 |
Beta blockers in neuroleptic-induced akathisia.
Topics: Adrenergic beta-Antagonists; Akathisia, Drug-Induced; Antipsychotic Agents; Humans; Propranolol; Psy | 1988 |
Successful propranolol therapy for neuroleptic-induced akathisia resistant to anticholinergic and benzodiazepine drugs.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Female; Humans; Male; Propranolol; P | 1988 |
Propranolol in the treatment of tardive akathisia: a report of two cases.
Topics: Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Humans; Propranolol; Psychomotor Agitat | 1988 |
[Propranolol in the treatment of neuroleptic-induced akathisia].
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Female; Humans; Male; Propranolol; | 1988 |
Propranolol and clonidine in detoxification.
Topics: Clonidine; Humans; Lorazepam; Methadone; Opioid-Related Disorders; Propranolol; Psychomotor Agitatio | 1988 |
Propranolol as adjunct to clonidine in opiate detoxification.
Topics: Adult; Clonidine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Opioid-Related Disor | 1987 |
Emergency treatment of acute psychosis, agitation, and anxiety.
Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran | 1985 |