propranolol has been researched along with Pre-Eclampsia in 14 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 9.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 5.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "In a double blind study, 20 gravidas with pre-eclampsia were randomly allocated to treatment with either propranolol 120 mg/day or pindolol 15 mg/day for 7 days." | 5.07 | Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol. ( Holcberg, G; Insler, V; Katz, M; Meizner, I; Paran, E, 1992) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 1.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "Autonomic hyperreflexia is a serious peripartum complication associated with spinal cord lesions." | 1.27 | Management of autonomic hyperreflexia associated with a low thoracic spinal cord lesion. ( Gimovsky, ML; Ojeda, A; Ozaki, R; Zerne, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, L | 1 |
| Ng, A | 1 |
| Chen, W | 1 |
| Spencer, HT | 1 |
| Nguyen, J | 1 |
| Shen, AY | 1 |
| Lee, MS | 1 |
| Spradley, FT | 1 |
| Ge, Y | 1 |
| Haynes, BP | 1 |
| Granger, JP | 1 |
| Anderson, CD | 1 |
| Fuerst, M | 1 |
| Berkowitz, RL | 1 |
| Rabinerson, D | 1 |
| Kaplan, B | 1 |
| Royburt, M | 1 |
| Gruber, A | 1 |
| Alexander, N | 1 |
| Monnier, JC | 1 |
| Honore, P | 1 |
| Lanciaux, B | 1 |
| Boulogne, M | 1 |
| Woods, JR | 1 |
| Brinkman, CR | 1 |
| Meizner, I | 1 |
| Paran, E | 1 |
| Katz, M | 1 |
| Holcberg, G | 1 |
| Insler, V | 1 |
| Schoenfeld, A | 1 |
| Freedman, S | 1 |
| Hod, M | 1 |
| Ovadia, Y | 1 |
| Fogari, R | 1 |
| Zoppi, A | 1 |
| Gimovsky, ML | 1 |
| Ojeda, A | 1 |
| Ozaki, R | 1 |
| Zerne, S | 1 |
| Kincaid-Smith, P | 1 |
| Seedat, YK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Pre-Eclampsia
| Article | Year |
|---|---|
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide | 1980 |
[Beta-blockers in the therapy of arterial hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Diuretics; Female; Humans; Hypertension; Methyldopa; Oxprenolol; Pre-Ec | 1985 |
2 trials available for propranolol and Pre-Eclampsia
| Article | Year |
|---|---|
Beta-blockers may have role in preeclampsia.
Topics: Adrenergic beta-Antagonists; Atenolol; Birth Weight; Clinical Trials as Topic; Female; Humans; Hyper | 1982 |
Flow velocity analysis of umbilical and uterine artery flow in pre-eclampsia treated with propranolol or pindolol.
Topics: Adult; Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Pindolol; Placenta; Pre-E | 1992 |
10 other studies available for propranolol and Pre-Eclampsia
| Article | Year |
|---|---|
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi | 2017 |
Adrenergic receptor blockade attenuates placental ischemia-induced hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Femal | 2018 |
Imaging techniques in an eclamptic patient-demonstration of spinal cord lesion using MRI.
Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Eclampsia; Female; HELLP Syndrome; Humans; I | 1995 |
[Value of hydralazine-beta blockader association in hypertension of pregnancy].
Topics: Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female; Fetus; Humans; Hydralazine; H | 1978 |
Letter: Hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Female; Fetal Death; Fetal Distress; Fetal Heart; Fetus; Heart Rate; Hu | 1975 |
The treatment of gestational hypertension.
Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype | 1975 |
Antagonism of antihypertensive drug therapy in pregnancy by indomethacin?
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Indomethacin; Obstetric Labor, Prema | 1989 |
Management of autonomic hyperreflexia associated with a low thoracic spinal cord lesion.
Topics: Adult; Autonomic Nervous System Diseases; Cesarean Section; Female; Humans; Hydralazine; Obstetric L | 1985 |
Management of severe hypertension.
Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intra | 1973 |
Prindolol in the management of hypertension.
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Pindo | 1974 |