Page last updated: 2024-11-03

propranolol and Postural Orthostatic Tachycardia Syndrome

propranolol has been researched along with Postural Orthostatic Tachycardia Syndrome in 12 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Postural Orthostatic Tachycardia Syndrome: A syndrome of ORTHOSTATIC INTOLERANCE combined with excessive upright TACHYCARDIA, and usually without associated ORTHOSTATIC HYPOTENSION. All variants have in common an excessively reduced venous return to the heart (central HYPOVOLEMIA) while upright.

Research Excerpts

ExcerptRelevanceReference
"Low-dose oral propranolol significantly attenuated tachycardia and improved symptoms in POTS."9.14Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more. ( Biaggioni, I; Black, BK; Dupont, WD; Paranjape, SY; Raj, SR; Ramirez, M; Robertson, D, 2009)
"To evaluate the short-term effectiveness of reduced-osmolarity oral rehydration salt formulation (ORS) and propranolol in children diagnosed with postural orthostatic tachycardia syndrome (POTS) in head-up tilt testing (HUTT)."5.34Short-term efficacy of ORS formulation and propranolol regimen in children with POTS. ( Coban, S; Erenberk, U; Ergor, SN; Karaarslan, U; Karadeniz, C; Oner, T; Temur, HO; Yozgat, CY; Yozgat, Y, 2020)
"Low-dose oral propranolol significantly attenuated tachycardia and improved symptoms in POTS."5.14Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more. ( Biaggioni, I; Black, BK; Dupont, WD; Paranjape, SY; Raj, SR; Ramirez, M; Robertson, D, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Chung, HY1
Essig, F1
Wickel, J1
Besteher, B1
Neugebauer, H1
Haeusler, KG1
Müllges, W1
Schwab, M1
Goodman, B1
Jariwala, S1
Yozgat, Y1
Temur, HO1
Coban, S1
Oner, T1
Karaarslan, U1
Yozgat, CY1
Karadeniz, C1
Ergor, SN1
Erenberk, U1
Smith, EC1
Diedrich, A2
Raj, SR3
Gamboa, A2
Shibao, CA1
Black, BK2
Peltier, A1
Paranjape, SY3
Biaggioni, I3
Okamoto, LE2
Kim, P1
During, E1
Miglis, M1
Moon, J1
Kim, DY1
Lee, WJ1
Lee, HS1
Lim, JA1
Kim, TJ1
Jun, JS1
Park, B1
Byun, JI1
Sunwoo, JS1
Lee, ST1
Jung, KH1
Park, KI1
Jung, KY1
Kim, M1
Lee, SK1
Chu, K1
Casas, G1
Rivas-Gándara, N1
Francisco-Pascual, J1
Moya-Mitjans, À1
García-Dorado, D1
Arnold, AC1
Noyes, AM1
Kluger, J1
Ramirez, M1
Dupont, WD1
Robertson, D1
Fu, Q1
Vangundy, TB1
Shibata, S1
Auchus, RJ1
Williams, GH1
Levine, BD1
Kimpinski, K1
Figueroa, JJ1
Singer, W1
Sletten, DM1
Iodice, V1
Sandroni, P1
Fischer, PR1
Opfer-Gehrking, TL1
Gehrking, JA1
Low, PA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Orthostatic Intolerance[NCT00262470]Phase 1/Phase 2150 participants (Anticipated)Interventional1997-04-30Active, not recruiting
Comparison of Effect of Propranolol, Bisoprolol, Pyridosgitmine in Postural Orthostatic Tachycardia Syndrome (POTS) and Prognosis After Medical Treatment[NCT02171988]Phase 4150 participants (Actual)Interventional2014-03-31Completed
Post-Acute Sequelae of Coronavirus-19 (COVID-19) With DysPnEA on ExertIon And Associated TaChycardia TrEatment Study[NCT05096884]Early Phase 120 participants (Anticipated)Interventional2022-03-23Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for propranolol and Postural Orthostatic Tachycardia Syndrome

ArticleYear
Short-term efficacy of ORS formulation and propranolol regimen in children with POTS.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2020, Volume: 27, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Child; Combined Modality Therapy; Electrolytes; Female; Flu

2020
Splanchnic Venous Compression Enhances the Effects of ß-Blockade in the Treatment of Postural Tachycardia Syndrome.
    Journal of the American Heart Association, 2020, 07-21, Volume: 9, Issue:14

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Compression Bandages; Cross-Over Studies; Female

2020
Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomized Clinical Trial.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2018, Volume: 15, Issue:3

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Bisoprolol; Female; Foll

2018
Low-dose propranolol and exercise capacity in postural tachycardia syndrome: a randomized study.
    Neurology, 2013, May-21, Volume: 80, Issue:21

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Humans; Oxygen Consumption; P

2013
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
    Circulation, 2009, Sep-01, Volume: 120, Issue:9

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cross-Over Studies; Dose-R

2009
Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Double-Blind Method; Exercise Thera

2011

Other Studies

6 other studies available for propranolol and Postural Orthostatic Tachycardia Syndrome

ArticleYear
Acute onset and severe manifestation of postural orthostatic tachycardia syndrome - Two cases.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2020, Volume: 131, Issue:1

    Topics: Anti-Arrhythmia Agents; Cerebrovascular Circulation; Dizziness; Female; Heart Rate; Humans; Postural

2020
Dupilumab as a novel therapy to treat adrenergic urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2021, Volume: 126, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Antibodies, Monoclonal, Humanized; Exanthema; Histamine Ant

2021
A Case of Narcolepsy Type 2 and Postural Tachycardia Syndrome Secondary to Lesions of the Thalamus and Amygdala.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018, 03-15, Volume: 14, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Amphetamine; Amygdala; Central Nervous System Stimulants; D

2018
Postural Orthostatic Tachycardia Syndrome and Vasospastic Angina: Therapeutic Approach to a Previously Unreported Association.
    Revista espanola de cardiologia (English ed.), 2019, Volume: 72, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris, Variant; Anti-Inflammatory Agents; Cardiovascular Agen

2019
A tale of two syndromes: Lyme disease preceding postural orthostatic tachycardia syndrome.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2015, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Diet, Gluten-Free; Female; Fluid Therapy; Humans; Lyme Di

2015
A prospective, 1-year follow-up study of postural tachycardia syndrome.
    Mayo Clinic proceedings, 2012, Volume: 87, Issue:8

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adult; Anti-Inflammato

2012