Page last updated: 2024-11-03

propranolol and Poisoning

propranolol has been researched along with Poisoning in 27 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"In a previous study of propranolol poisoning, glucagon and milrinone significantly increased cardiac output, but the improvement caused by glucagon was almost entirely due to the chronotropic effect."7.69Combined use of glucagon and milrinone may not be preferable for severe propranolol poisoning in the canine model. ( Naito, H; Nishimoto, C; Okubo, N; Sato, S; Tsuji, MH, 1995)
"Propranolol was responsible for the greatest number of exposures (44%) and implicated as the cause of death in a disproportionately high percentage of fatalities (71%)."2.40Characterization of fatal beta blocker ingestion: a review of the American Association of Poison Control Centers data from 1985 to 1995. ( Clancy, C; Howell, JM; Litovitz, TL; Love, JN, 1997)
" Thirty minutes after the development of toxicity, toxic measures were taken (treatment 0 minutes), and then the animals (n = 6 each group) received either sham (saline solution), insulin (4 IU/minute with glucose clamped), glucagon (50 micrograms/kg bolus, then 150 micrograms/kg/hour infusion), or epinephrine (1 microgram/kg/minute)."1.30Insulin improves survival in a canine model of acute beta-blocker toxicity. ( Kerns, W; Raymond, R; Schroeder, D; Tomaszewski, C; Williams, C, 1997)
"IV propranolol was used as the initial treatment for his hyperadrenergic state, resulting in a decrease in heart rate but a paroxsymal increase in blood pressure."1.27Propranolol-induced hypertension in treatment of cocaine intoxication. ( Ramoska, E; Sacchetti, AD, 1985)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's8 (29.63)18.2507
2000's4 (14.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Luis, DA1
Abad, L1
Aller, R1
González-Sagrado, M1
Dueñas, A1
Holger, JS1
Engebretsen, KM1
Obetz, CL1
Kleven, TL1
Harris, CR1
Sakamoto, T1
Yoshioka, T1
Shirakawa, Y1
Kamei, T1
Murata, A1
Asari, Y1
Okumura, T1
Endo, Y1
Shimazu, T1
Tomioka, J1
Kosolcharoen, P1
Patel, AK1
Thomsen, JH1
Stein, G1
Demme, U1
Sperschneider, H1
Fünfstück, R1
Werner, R1
Meier, F1
Günther, K1
Sato, S1
Tsuji, MH1
Okubo, N1
Nishimoto, C1
Naito, H1
Gustafson, BW1
Duffy, N1
Toet, AE1
te Biesebeek, JD1
Vleeming, W1
Wemer, J1
Meulenbelt, J1
de Wildt, DJ1
Love, JN3
Hanfling, D1
Howell, JM3
Kerns, W1
Schroeder, D1
Williams, C1
Tomaszewski, C1
Raymond, R1
Litovitz, TL1
Clancy, C1
Chodorowski, Z1
Sein Anand, J1
Newsome, JT1
Skibbie, DF1
Dickerson, LW1
Henderson, KJ1
Fine, SR1
Weinstein, RS1
Cole, S1
Knaster, HB1
Dahlbert, T1
Cassidy, SL1
Lympany, PA1
Henry, JA1
Ramoska, E1
Sacchetti, AD1
Rosner, I1
Romero-Ferret, C1
Mottot, G1
Jefferson, JW1
Simmons, AV1
Carr, D1
Ross, EJ1
Sesso, AM1
Snyder, RC1
Schott, CE1
Gdyra, D1
Billip-Tomecka, Z1
Szajewski, JM1
Karamehmet, A1
Aytan, N1
Ozcanli, A1
Yamada, K1
Wharton, CF1
Bock, KD1
Merguet, P1
Schley, G1
Schümann, HJ1
Rausch-Stroomann, JG1
Hocevar, V1
Schröder, E1
Murata, T1

Reviews

4 reviews available for propranolol and Poisoning

ArticleYear
[Levothyroxine poisoning: clinical manifestations and therapeutic management].
    Anales de medicina interna (Madrid, Spain : 1984), 2004, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cardiovascular Diseases; Child; Cholestyramine Resi

2004
[Guidelines for the treatment of acute chemical poisoning-11-symptomatic therapy 4. Management of circulation for drug overdose and poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2007, Volume: 20, Issue:1

    Topics: Acute Disease; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiac

2007
Characterization of fatal beta blocker ingestion: a review of the American Association of Poison Control Centers data from 1985 to 1995.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Cause of Death; Female; Humans; Male; Midd

1997
Beta-adrenergic receptor blocking drugs in psychiatry.
    Archives of general psychiatry, 1974, Volume: 31, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Alcoholism; Amphetamine; Animals; Antidepressive Agents;

1974

Trials

1 trial available for propranolol and Poisoning

ArticleYear
Beta-adrenergic receptor blocking drugs in psychiatry.
    Archives of general psychiatry, 1974, Volume: 31, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Alcoholism; Amphetamine; Animals; Antidepressive Agents;

1974

Other Studies

23 other studies available for propranolol and Poisoning

ArticleYear
A comparison of vasopressin and glucagon in beta-blocker induced toxicity.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Disease Models, Animal; Glucagon; Heart Rate;

2006
Isoproterenol overdose.
    Wisconsin medical journal, 1981, Volume: 80, Issue:9

    Topics: Accidents; Fluid Therapy; Humans; Isoproterenol; Male; Middle Aged; Poisoning; Propranolol

1981
[Detoxication by hemoperfusion].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Dec-15, Volume: 36, Issue:24

    Topics: Adolescent; Adult; Aged; Female; Hemoperfusion; Humans; Hydrocarbons, Halogenated; Hypnotics and Sed

1981
Combined use of glucagon and milrinone may not be preferable for severe propranolol poisoning in the canine model.
    Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:4

    Topics: Animals; Cardiotonic Agents; Dogs; Drug Therapy, Combination; Glucagon; Heart Rate; Milrinone; Poiso

1995
Terbutaline toxicosis in a dog.
    Journal of the American Veterinary Medical Association, 1994, Jun-15, Volume: 204, Issue:12

    Topics: Animals; Dog Diseases; Dogs; Electrocardiography; Female; Fluid Therapy; Heart; Infusions, Intraveno

1994
A 33-year-old woman with a propranolol and chlorpromazine overdose, with applied nursing diagnoses.
    Journal of emergency nursing, 1993, Volume: 19, Issue:1

    Topics: Adult; Chlorpromazine; Critical Care; Drug Overdose; Education, Nursing, Continuing; Female; Glucago

1993
Reduced survival after isoprenaline/dopamine in d,l-propranolol intoxicated rats.
    Human & experimental toxicology, 1996, Volume: 15, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Blood Gas Analysis; Blood

1996
Hemodynamic effects of calcium chloride in a canine model of acute propranolol intoxication.
    Annals of emergency medicine, 1996, Volume: 28, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Bradycardia; Calcium Chloride; Disease Models,

1996
Insulin improves survival in a canine model of acute beta-blocker toxicity.
    Annals of emergency medicine, 1997, Volume: 29, Issue:6

    Topics: Acute Disease; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antidotes; Disease Mo

1997
Acute poisoning with clenbuterol--a case report.
    Przeglad lekarski, 1997, Volume: 54, Issue:10

    Topics: Adrenergic beta-Agonists; Adult; Clenbuterol; Drug Administration Schedule; Drug Overdose; Humans; M

1997
The effect of sodium bicarbonate on propranolol-induced cardiovascular toxicity in a canine model.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:4

    Topics: Animals; Bicarbonates; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Dogs; Electr

2000
Adverse drug reactions.
    Cutis, 1976, Volume: 17, Issue:6

    Topics: Asthma; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Enzymes; Humans; Med

1976
Beta blocker overdose with propranolol and with atenolol.
    Annals of emergency medicine, 1985, Volume: 14, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Female; Glucagon; Humans; Poisoning; Propr

1985
Lipid solubility of a series of drugs and its relevance to fatal poisoning.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:2

    Topics: Humans; Lipids; Octanols; Pharmaceutical Preparations; Poisoning; Propranolol; Solubility

1988
Propranolol-induced hypertension in treatment of cocaine intoxication.
    Annals of emergency medicine, 1985, Volume: 14, Issue:11

    Topics: Cocaine; Emergencies; Humans; Male; Middle Aged; Nitroprusside; Poisoning; Propranolol

1985
Letter: Treatment of acute paracetamol poisoning.
    Lancet (London, England), 1973, Dec-01, Volume: 2, Issue:7840

    Topics: Acetaminophen; Alprenolol; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationsh

1973
Case of self-poisoning with multiple antidepressant drugs.
    Lancet (London, England), 1970, Jan-31, Volume: 1, Issue:7640

    Topics: Adult; Antidepressive Agents; Blood Pressure; Cheese; Dibenzocycloheptenes; Fever; Humans; Intubatio

1970
Propranolol in imipramine poisoning.
    American journal of diseases of children (1960), 1973, Volume: 126, Issue:6

    Topics: Electric Countershock; Female; Gastric Lavage; Humans; Imipramine; Poisoning; Propranolol; Respirati

1973
[Case of poisoning with a 4-gram dose of propranolol].
    Polskie Archiwum Medycyny Wewnetrznej, 1973, Volume: 50, Issue:12

    Topics: Adult; Atropine; Electrocardiography; Heart; Humans; Male; Methimazole; Poisoning; Propranolol

1973
[Propranolol in digitalis intoxication].
    Turk Tip Cemiyeti mecmuasi, 1969, Volume: 35, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Digitalis Glycosides; Dogs; Electrocardiography; Poisoning; Propranol

1969
[Influence of propranolol and other drugs on ouabain poisoning, with special reference to the relation to heart rate].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Sep-20, Volume: 65, Issue:5

    Topics: Animals; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hexamethonium Compounds; Injections,

1969
Attempted suicide by digoxin self administration and its management.
    Guy's Hospital reports, 1970, Volume: 119, Issue:3

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Digoxin; Electrocardiography; Female; Human

1970
[On pathogenesis of hypertension and tachycardia in acute thallium poisoning and in acute intermittent porphyria].
    Deutsche medizinische Wochenschrift (1946), 1968, Nov-01, Volume: 93, Issue:44

    Topics: Adult; Female; Humans; Hypertension; Levulinic Acids; Male; Phentolamine; Poisoning; Porphyrias; Pro

1968