propranolol has been researched along with Panic Disorder in 9 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the efficacy of propranolol (Inderal) compared to alprazolam (Xanax) in 29 patients with a diagnosis of agoraphobia with panic disorder or panic disorder with or without limited phobic avoidance in a 6-week double-blind controlled experiment." | 5.07 | A controlled study of alprazolam and propranolol in panic-disordered and agoraphobic outpatients. ( Friedman, MJ; Hauri, PJ; McHugo, GJ; Ravaris, CL, 1991) |
| "Panic disorder is characterised by recurrent unexpected panic attacks consisting of a wave of intense fear that reaches a peak within a few minutes." | 2.61 | Benzodiazepines versus placebo for panic disorder in adults. ( Barbui, C; Bighelli, I; Breilmann, J; Castellazzi, M; Cipriani, A; Davies, SJ; Furukawa, TA; Girlanda, F; Guaiana, G; Koesters, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breilmann, J | 1 |
| Girlanda, F | 1 |
| Guaiana, G | 1 |
| Barbui, C | 1 |
| Cipriani, A | 1 |
| Castellazzi, M | 1 |
| Bighelli, I | 1 |
| Davies, SJ | 1 |
| Furukawa, TA | 1 |
| Koesters, M | 1 |
| Das, M | 1 |
| Roy-Byrne, PP | 1 |
| Sullivan, MD | 1 |
| Cowley, DS | 1 |
| Ries, RK | 1 |
| Munjack, DJ | 1 |
| Brown, RA | 1 |
| Cabe, DD | 1 |
| McDowell, DE | 1 |
| Baltazar, PL | 1 |
| Prabhu, SS | 1 |
| Joshi, NC | 1 |
| Laederach-Hofmann, K | 1 |
| Glauser, R | 1 |
| Le Mellédo, JM | 2 |
| Bradwejn, J | 2 |
| Koszycki, D | 2 |
| Bichet, DG | 1 |
| Bellavance, F | 2 |
| Arthur, H | 1 |
| Dalton, J | 1 |
| Woo, C | 1 |
| Lipton, N | 1 |
| Boulenger, JP | 1 |
| Ravaris, CL | 1 |
| Friedman, MJ | 1 |
| Hauri, PJ | 1 |
| McHugo, GJ | 1 |
3 reviews available for propranolol and Panic Disorder
| Article | Year |
|---|---|
Benzodiazepines versus placebo for panic disorder in adults.
Topics: Adult; Aged; Agoraphobia; Benzodiazepines; Buspirone; Humans; Imipramine; Middle Aged; Numbers Neede | 2019 |
Adjunctive treatment of benzodiazepine discontinuation syndromes: a review.
Topics: Anti-Anxiety Agents; Benzodiazepines; Carbamazepine; Clonidine; Combined Modality Therapy; Humans; P | 1993 |
Panic attack syndrome.
Topics: Age of Onset; Anti-Anxiety Agents; Child; Diagnosis, Differential; Humans; India; Male; Panic Disord | 1996 |
3 trials available for propranolol and Panic Disorder
| Article | Year |
|---|---|
The role of the beta-noradrenergic system in cholecystokinin-tetrapeptide-induced panic symptoms.
Topics: Adult; Humans; Male; Panic Disorder; Propranolol; Receptors, Adrenergic, beta; Tetragastrin | 1998 |
The influence of Type A behavior pattern on the response to the panicogenic agent CCK-4.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiovascular Physiol | 2001 |
A controlled study of alprazolam and propranolol in panic-disordered and agoraphobic outpatients.
Topics: Adolescent; Adult; Agoraphobia; Alprazolam; Double-Blind Method; Female; Humans; Male; Middle Aged; | 1991 |
3 other studies available for propranolol and Panic Disorder
| Article | Year |
|---|---|
Panic disorder: propranolol and behavioural therapy.
Topics: Anti-Anxiety Agents; Cognitive Behavioral Therapy; Humans; Panic Disorder; Propranolol | 2006 |
A naturalistic follow-up of panic patients after short-term pharmacologic treatment.
Topics: Adult; Alprazolam; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Age | 1993 |
Paroxysmal tachycardia in a patient without panic disorder.
Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Electrocardiography; Humans; Male; Middle Aged; Pan | 1998 |