Page last updated: 2024-11-03

propranolol and Orbital Neoplasms

propranolol has been researched along with Orbital Neoplasms in 37 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Orbital Neoplasms: Neoplasms of the bony orbit and contents except the eyeball.

Research Excerpts

ExcerptRelevanceReference
"Recent reports of propranolol for the treatment of hemangiomas have led many physicians to question the best treatment strategy for children with vision-threatening hemangiomas."8.89Hemangiomas treated with propranolol: do the rewards outweigh the risks? ( Haider, KM; Neely, DE; Plager, DA, 2013)
"To highlight the importance of Magnetic Resonance Imaging (MRI) and the use of propranolol as both a final diagnostic tool and adequate treatment for orbital Infantile Haemangiomas (IHs)."7.80Propranolol as first-line treatment in orbital infantile haemangiomas: a case series. ( Coumou, AD; Freling, NJ; Groeneveld, L; Levitt, M; Saeed, P; van der Horst, CM, 2014)
"To develop a tool for assessing amblyopic risk and monitoring the treatment effect of propranolol in periocular haemangioma management."7.80Monitoring propranolol treatment in periocular infantile haemangioma. ( Burne, R; Taylor, R, 2014)
"Propranolol is now widely used to treat severe infantile haemangiomas (IHs)."7.79Propranolol-resistant infantile haemangiomas. ( Aubert, H; Barbarot, S; Boccara, O; Bursztejn, AC; Caussé, S; Chiaverini, C; Dreyfus, I; Eschard, C; Hadj-Rabia, S; Mahé, E; Maruani, A; Mazereeuw-Hautier, J; Miquel, J; Puzenat, E; Saint-Jean, M; Stalder, JF, 2013)
"3 months) with periorbital proliferating phase infantile hemangioma underwent oral propranolol therapy."7.77[Oral propranolol in the management of periorbital proliferating phase infantile hemangioma]. ( Fu, HB; Guo, X; Huo, R; Lin, LL; Lü, RR; Wui, JC; Xu, GQ; Zhang, J; Zhao, ZF, 2011)
"Propranolol is a promising treatment against infantile haemangiomas in the orbit, not only in infants but also in an older child with a stable lesion."7.76Successful treatment of infantile haemangiomas of the orbit with propranolol. ( Li, YC; Martin, FJ; Martin, PA; McCahon, E; Rowe, NA; Wilcsek, GA, 2010)
"Propranolol appears to be a safe and effective treatment in the management of infantile haemangioma."7.76Propranolol in the management of periorbital infantile haemangioma. ( Cheng, JF; Gole, GA; Sullivan, TJ, 2010)
"Outpatient propranolol treatment reduced the size or stopped the growth of all hemangiomas treated, with excellent response in more than half of all patients treated and only minor side effects."7.76Outpatient treatment of periocular infantile hemangiomas with oral propranolol. ( Eikenberry, J; Haggstrom, A; Haider, KM; Neely, DE; Plager, DA, 2010)
"Recent reports of propranolol for the treatment of hemangiomas have led many physicians to question the best treatment strategy for children with vision-threatening hemangiomas."4.89Hemangiomas treated with propranolol: do the rewards outweigh the risks? ( Haider, KM; Neely, DE; Plager, DA, 2013)
"To the best of our knowledge, this is the first observation of a secondary congenital glaucoma reversal with oral propranolol used for orbital IH management."3.91Secondary Congenital Glaucoma Associated With Retro-orbital Infantile Hemangioma: A Masquerade Syndrome. ( Beylerian, M; Dambricourt, L; Denis, D; Matonti, F; Ramtohul, P, 2019)
"To highlight the importance of Magnetic Resonance Imaging (MRI) and the use of propranolol as both a final diagnostic tool and adequate treatment for orbital Infantile Haemangiomas (IHs)."3.80Propranolol as first-line treatment in orbital infantile haemangiomas: a case series. ( Coumou, AD; Freling, NJ; Groeneveld, L; Levitt, M; Saeed, P; van der Horst, CM, 2014)
"To develop a tool for assessing amblyopic risk and monitoring the treatment effect of propranolol in periocular haemangioma management."3.80Monitoring propranolol treatment in periocular infantile haemangioma. ( Burne, R; Taylor, R, 2014)
"Propranolol is now widely used to treat severe infantile haemangiomas (IHs)."3.79Propranolol-resistant infantile haemangiomas. ( Aubert, H; Barbarot, S; Boccara, O; Bursztejn, AC; Caussé, S; Chiaverini, C; Dreyfus, I; Eschard, C; Hadj-Rabia, S; Mahé, E; Maruani, A; Mazereeuw-Hautier, J; Miquel, J; Puzenat, E; Saint-Jean, M; Stalder, JF, 2013)
"3 months) with periorbital proliferating phase infantile hemangioma underwent oral propranolol therapy."3.77[Oral propranolol in the management of periorbital proliferating phase infantile hemangioma]. ( Fu, HB; Guo, X; Huo, R; Lin, LL; Lü, RR; Wui, JC; Xu, GQ; Zhang, J; Zhao, ZF, 2011)
"Propranolol is a promising treatment against infantile haemangiomas in the orbit, not only in infants but also in an older child with a stable lesion."3.76Successful treatment of infantile haemangiomas of the orbit with propranolol. ( Li, YC; Martin, FJ; Martin, PA; McCahon, E; Rowe, NA; Wilcsek, GA, 2010)
"Propranolol appears to be a safe and effective treatment in the management of infantile haemangioma."3.76Propranolol in the management of periorbital infantile haemangioma. ( Cheng, JF; Gole, GA; Sullivan, TJ, 2010)
"Outpatient propranolol treatment reduced the size or stopped the growth of all hemangiomas treated, with excellent response in more than half of all patients treated and only minor side effects."3.76Outpatient treatment of periocular infantile hemangiomas with oral propranolol. ( Eikenberry, J; Haggstrom, A; Haider, KM; Neely, DE; Plager, DA, 2010)
"To evaluate the medical literature on the use of β-blockers, through different routes, for the treatment of periorbital infantile hemangiomas and to summarize the recommendations available on dosage and monitoring."2.61β-blockers in the treatment of periocular infantile hemangioma. ( Al-Haddad, C; El Moussawi, Z; El Salloukh, NA, 2019)
" As per the guideline, a preliminary paediatric assessment was performed and a 1 mg/kg test dose was administered, followed by definitive treatment at a dosage of 2 mg/kg in three divided doses."2.61Orbital infantile haemangioma: radiological features and treatment - case series and literature review. ( Albanese, G; Mohandas, P; Ravenscroft, J; Srinivasan, J; Tambe, K; Taylor, T; Thomas, S; Wells, L, 2019)
" Additional research may confirm the best dosage and route of administration to maximize efficacy in reducing induced astigmatism and amblyopia associated with periocular hemangiomas while minimizing side effects."2.61The Use of β-Blockers for the Treatment of Periocular Hemangiomas in Infants: A Report by the American Academy of Ophthalmology. ( Galvin, JA; Hutchinson, AK; Kraker, RT; Lambert, SR; Pineles, SL; VanderVeen, DK; Wilson, LB, 2019)
"Propranolol has been suggested as the new standard of care for treatment of IH."2.49Infantile hemangioma: treatment with surgery or steroids. ( Mawn, LA, 2013)
"Propranolol has recently been reported to be an effective and safe alternative."2.47The use of propranolol in the management of periocular capillary haemangioma--a systematic review. ( Reddy, AR; Spiteri Cornish, K, 2011)
"Mean astigmatism in affected eyes was 1."1.43Visual acuity and astigmatism in periocular infantile hemangiomas treated with oral beta-blocker versus intralesional corticosteroid injection. ( Herlihy, EP; Kelly, JP; Perkins, JA; Sidbury, R; Weiss, AH, 2016)
"Adult hemangiomas are usually benign vascular tumors presenting as painless progressive proptosis, sometimes accompanied by serious visual loss due to compression of the optic nerve."1.38Management of adult onset orbital hemangioma by oral propranalol: a case report. ( Goswami, M; Murthy, GJ, 2012)
"Oral propranolol for treatment of infantile hemangiomas was effective in all patients, with 33% reduction in astigmatism and 39% reduction in surface area."1.37Oral propranolol for treatment of periocular infantile hemangiomas. ( Bayliss, SJ; Gilbertson, K; Lueder, GT; Missoi, TG, 2011)
" A treatment dosage of 2 mg/kg per day was started at mean age 5."1.37Refractive and structural changes in infantile periocular capillary haemangioma treated with propranolol. ( Ben-Amitay, D; Friling, R; Goldenberg-Cohen, N; Reich, U; Ron, Y; Siegel, R; Snir, M; Zvulunov, A, 2011)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's36 (97.30)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Al-Haddad, C1
El Salloukh, NA1
El Moussawi, Z1
Mehta, A1
Bajaj, MS1
Pushker, N1
Chawla, B1
Pujari, A1
Grewal, SS1
Grewal, SPS1
Singh, SR1
Kishore, A1
Yadav, NS1
Sazali, HB1
Allen, NM1
Murphy, A1
Albanese, G1
Mohandas, P1
Wells, L1
Ravenscroft, J1
Srinivasan, J1
Thomas, S1
Taylor, T1
Tambe, K1
Hutchinson, AK1
Kraker, RT1
Pineles, SL1
VanderVeen, DK1
Wilson, LB1
Galvin, JA1
Lambert, SR1
Lee, SM1
Khwarg, SI1
Ahn, JH1
Ramtohul, P1
Beylerian, M1
Dambricourt, L1
Matonti, F1
Denis, D1
Caussé, S1
Aubert, H1
Saint-Jean, M1
Puzenat, E1
Bursztejn, AC1
Eschard, C1
Mahé, E1
Maruani, A1
Mazereeuw-Hautier, J1
Dreyfus, I1
Miquel, J1
Chiaverini, C1
Boccara, O1
Hadj-Rabia, S1
Stalder, JF1
Barbarot, S1
Haider, KM2
Neely, DE2
Plager, DA2
Mawn, LA1
Puligadda, RK1
Vijayalakshmi, B1
Levitt, M1
Coumou, AD1
Groeneveld, L1
Freling, NJ1
van der Horst, CM1
Saeed, P1
Xu, S1
Jia, R1
Ge, S1
Lin, M1
Fan, X1
Burne, R1
Taylor, R1
Sterker, I1
Tegetmeyer, H1
Sorge, I1
Weißer, M1
Böhm, R1
Herlihy, EP1
Kelly, JP1
Sidbury, R1
Perkins, JA1
Weiss, AH1
Taban, M1
Goldberg, RA1
Fay, A1
Nguyen, J1
Jakobiec, FA1
Meyer-Junghaenel, L1
Waner, M1
Li, YC1
McCahon, E1
Rowe, NA1
Martin, PA1
Wilcsek, GA1
Martin, FJ1
Cheng, JF1
Gole, GA1
Sullivan, TJ1
Cruz, OA1
Siegfried, EC1
Eikenberry, J1
Haggstrom, A1
Sloan, B1
Mora, J1
Dai, S1
Claerhout, I1
Buijsrogge, M1
Delbeke, P1
Walraedt, S1
De Schepper, S1
De Moerloose, B1
De Groote, K1
Decock, C1
Mai, C1
Vega-Pérez, A1
Koch, M1
Bertelmann, E1
Missoi, TG1
Lueder, GT1
Gilbertson, K1
Bayliss, SJ1
Spierer, O1
Neudorfer, M1
Leibovitch, I1
Stolovitch, C1
Kessler, A1
Thoumazet, F1
Léauté-Labrèze, C1
Colin, J1
Mortemousque, B1
Spiteri Cornish, K1
Reddy, AR1
Zhao, ZF1
Lü, RR1
Zhang, J1
Huo, R1
Xu, GQ1
Fu, HB1
Guo, X1
Wui, JC1
Lin, LL1
Snir, M1
Reich, U1
Siegel, R1
Zvulunov, A1
Friling, R1
Goldenberg-Cohen, N1
Ron, Y1
Ben-Amitay, D1
Aletaha, M1
Salour, H1
Bagheri, A1
Raffati, N1
Amouhashemi, N1
Clifford, L1
May, K1
Norris, JH1
McCulloch, PG1
Murthy, GJ1
Goswami, M1
Xue, K1
Hildebrand, GD1
Salazar-Murillo, R1
García-Pacheco, S1
González-Blanco, MJ1
Bolívar-Montesa, P1
Campos-García, S1

Reviews

9 reviews available for propranolol and Orbital Neoplasms

ArticleYear
β-blockers in the treatment of periocular infantile hemangioma.
    Current opinion in ophthalmology, 2019, Volume: 30, Issue:5

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Female; Hemangioma, Capillary; Humans; Infant; Ma

2019
Orbital infantile haemangioma: radiological features and treatment - case series and literature review.
    Orbit (Amsterdam, Netherlands), 2019, Volume: 38, Issue:1

    Topics: Female; Hemangioma, Capillary; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Or

2019
The Use of β-Blockers for the Treatment of Periocular Hemangiomas in Infants: A Report by the American Academy of Ophthalmology.
    Ophthalmology, 2019, Volume: 126, Issue:1

    Topics: Academies and Institutes; Adrenergic beta-Antagonists; Child, Preschool; Eyelid Neoplasms; Hemangiom

2019
Hemangiomas treated with propranolol: do the rewards outweigh the risks?
    The American orthoptic journal, 2013, Volume: 63

    Topics: Adrenergic beta-Antagonists; Child; Hemangioma; Humans; Orbital Neoplasms; Propranolol; Treatment Ou

2013
Infantile hemangioma: treatment with surgery or steroids.
    The American orthoptic journal, 2013, Volume: 63

    Topics: Adrenergic beta-Antagonists; Glucocorticoids; Hemangioma; Humans; Infant; Ophthalmologic Surgical Pr

2013
Treatment of periorbital infantile haemangiomas: a systematic literature review on propranolol or steroids.
    Journal of paediatrics and child health, 2014, Volume: 50, Issue:4

    Topics: Adrenal Cortex Hormones; Hemangioma, Capillary; Humans; Infant; Orbital Neoplasms; Propranolol; Vaso

2014
[Propranolol therapy for periocular and orbital infantile haemangiomas].
    Klinische Monatsblatter fur Augenheilkunde, 2014, Volume: 231, Issue:10

    Topics: Adrenergic beta-Antagonists; Female; Hemangioma; Humans; Infant, Newborn; Male; Orbital Neoplasms; P

2014
The use of propranolol in the treatment of periocular infantile haemangiomas: a review.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:9

    Topics: Adrenergic beta-Antagonists; Disease Progression; Eye Neoplasms; Hemangioma, Capillary; Humans; Infa

2011
The use of propranolol in the management of periocular capillary haemangioma--a systematic review.
    Eye (London, England), 2011, Volume: 25, Issue:10

    Topics: Administration, Oral; Antineoplastic Agents; Child, Preschool; Disease Progression; Evidence-Based M

2011

Trials

1 trial available for propranolol and Orbital Neoplasms

ArticleYear
To compare intralesional and oral propranolol for treating periorbital and eyelid capillary hemangiomas.
    Indian journal of ophthalmology, 2019, Volume: 67, Issue:12

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Eyelid Neoplasms; Female; Hemangioma, Capillary;

2019

Other Studies

27 other studies available for propranolol and Orbital Neoplasms

ArticleYear
PHACE syndrome: importance of distinguishing infantile haemangioma from capillary malformation.
    Archives of disease in childhood. Fetal and neonatal edition, 2020, Volume: 105, Issue:6

    Topics: Adrenergic beta-Antagonists; Aortic Coarctation; Diagnosis, Differential; Eye Abnormalities; Female;

2020
Epithelioid hemangioma of the orbit treated with oral propranolol in adult.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2018, Volume: 53, Issue:6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Hemangioma; Hum

2018
Secondary Congenital Glaucoma Associated With Retro-orbital Infantile Hemangioma: A Masquerade Syndrome.
    Journal of glaucoma, 2019, Volume: 28, Issue:6

    Topics: Diagnosis, Differential; Female; Glaucoma; Hemangioma; Humans; Hydrophthalmos; Infant; Intraocular P

2019
Propranolol-resistant infantile haemangiomas.
    The British journal of dermatology, 2013, Volume: 169, Issue:1

    Topics: Age of Onset; Antineoplastic Agents; Child, Preschool; Drug Resistance, Neoplasm; Facial Neoplasms;

2013
Large orbital hemangioma: managed with systemic propranolol.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:8

    Topics: Administration, Oral; Hemangioma; Humans; Infant; Male; Orbital Neoplasms; Propranolol

2014
Propranolol as first-line treatment in orbital infantile haemangiomas: a case series.
    Orbit (Amsterdam, Netherlands), 2014, Volume: 33, Issue:3

    Topics: Administration, Oral; Contrast Media; Female; Hemangioma; Humans; Infant; Magnetic Resonance Imaging

2014
Monitoring propranolol treatment in periocular infantile haemangioma.
    Eye (London, England), 2014, Volume: 28, Issue:11

    Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Amblyopia; Child; Child, Preschool; D

2014
Visual acuity and astigmatism in periocular infantile hemangiomas treated with oral beta-blocker versus intralesional corticosteroid injection.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2016, Volume: 20, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Astigmatism; Eyelid Neoplasms; Female; Glucocorti

2016
Propranolol for orbital hemangioma.
    Ophthalmology, 2010, Volume: 117, Issue:1

    Topics: Adrenergic beta-Antagonists; Female; Hemangioma, Capillary; Humans; Infant; Magnetic Resonance Imagi

2010
Propranolol for isolated orbital infantile hemangioma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Biomarkers, Tumor; Female; Hemangioma; Humans; In

2010
Successful treatment of infantile haemangiomas of the orbit with propranolol.
    Clinical & experimental ophthalmology, 2010, Volume: 38, Issue:6

    Topics: Adrenergic beta-Antagonists; Child, Preschool; Female; Hemangioma; Humans; Infant; Magnetic Resonanc

2010
Propranolol in the management of periorbital infantile haemangioma.
    Clinical & experimental ophthalmology, 2010, Volume: 38, Issue:6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Astigmatism; Eyelid Neoplasms; Female; Hemangioma

2010
Propranolol treatment for periocular capillary hemangiomas.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2010, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Hemangioma, Capillary; Humans; Infant; Orbital Neoplasms; Propranolol

2010
Outpatient treatment of periocular infantile hemangiomas with oral propranolol.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2010, Volume: 14, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Hemangioma; Humans; Infant; Infant, Newborn; Orbi

2010
Everything old is new again.
    Clinical & experimental ophthalmology, 2010, Volume: 38, Issue:6

    Topics: Adrenergic beta-Antagonists; Hemangioma, Capillary; Humans; Orbital Neoplasms; Propranolol

2010
[Successful treatment of orbital capillary hemangioma with propranolol].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011, Volume: 108, Issue:4

    Topics: Adrenergic beta-Antagonists; Biopsy; Exophthalmos; Female; Hemangioma, Capillary; Humans; Infant; Ma

2011
Oral propranolol for treatment of periocular infantile hemangiomas.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2011, Volume: 129, Issue:7

    Topics: Administration, Oral; Antineoplastic Agents; Child, Preschool; Eyelid Neoplasms; Female; Hemangioma,

2011
Colour Doppler ultrasound imaging findings in paediatric periocular and orbital haemangiomas.
    Acta ophthalmologica, 2012, Volume: 90, Issue:8

    Topics: Adrenergic beta-Antagonists; Blood Flow Velocity; Eyelid Neoplasms; Female; Follow-Up Studies; Gluco

2012
Efficacy of systemic propranolol for severe infantile haemangioma of the orbit and eyelid: a case study of eight patients.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Child, Preschool; Eyelid Neoplasms; Follow-Up Stu

2012
[Oral propranolol in the management of periorbital proliferating phase infantile hemangioma].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2011, Volume: 27, Issue:3

    Topics: Child; Child, Preschool; Female; Hemangioma; Humans; Infant; Male; Orbital Neoplasms; Propranolol; R

2011
Refractive and structural changes in infantile periocular capillary haemangioma treated with propranolol.
    Eye (London, England), 2011, Volume: 25, Issue:12

    Topics: Adrenergic beta-Antagonists; Eyelid Neoplasms; Female; Hemangioma, Capillary; Humans; Infant; Male;

2011
Successful treatment of orbital hemangioma with propranolol in a 5-year-old girl.
    Orbit (Amsterdam, Netherlands), 2012, Volume: 31, Issue:1

    Topics: Child, Preschool; Female; Hemangioma, Capillary; Humans; Orbital Neoplasms; Propranolol

2012
Reply to Spiteri Cornish and Reddy.
    Eye (London, England), 2012, Volume: 26, Issue:4

    Topics: Antineoplastic Agents; Female; Hemangioma, Capillary; Humans; Male; Orbital Neoplasms; Propranolol

2012
Re: The use of propranolol in the management of periocular capillary haemangioma--a systematic review.
    Eye (London, England), 2012, Volume: 26, Issue:9

    Topics: Antineoplastic Agents; Female; Hemangioma, Capillary; Humans; Male; Orbital Neoplasms; Propranolol

2012
Management of adult onset orbital hemangioma by oral propranalol: a case report.
    Orbit (Amsterdam, Netherlands), 2012, Volume: 31, Issue:5

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Diagnosis, Differential; Female; Hemangioma; Huma

2012
Topical timolol maleate 0.5% for infantile capillary haemangioma of the eyelid.
    The British journal of ophthalmology, 2012, Volume: 96, Issue:12

    Topics: Adrenergic beta-Antagonists; Eyelid Neoplasms; Hemangioma, Capillary; Humans; Orbital Neoplasms; Pro

2012
[Propranolol: Treatment of capillary hemangioma with orbital involvement].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:12

    Topics: Disease Progression; Eyelid Neoplasms; Facial Neoplasms; Female; Hemangioma, Capillary; Humans; Infa

2012