Page last updated: 2024-11-03

propranolol and Nociceptive Pain

propranolol has been researched along with Nociceptive Pain in 2 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.

Research Excerpts

ExcerptRelevanceReference
"Background Migraine is a highly prevalent and disabling disorder of the brain with limited therapeutic options, particularly for preventive treatment."1.48Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation. ( Akerman, S; Goadsby, PJ; Martins-Oliveira, M; Zhao, Y, 2018)
" The potencies and equipotent doses were determined for infiltrative cutaneous analgesia on the rat back by determination of dose-response curves for propranolol and lidocaine."1.38Propranolol elicits cutaneous analgesia against skin nociceptive stimuli in rats. ( Chen, YC; Chen, YW; Chu, CC; Hung, CH; Wang, JJ, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, Y1
Martins-Oliveira, M1
Akerman, S1
Goadsby, PJ1
Chen, YW1
Chu, CC1
Chen, YC1
Hung, CH1
Wang, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Contribution of COMT Haplotypes in Propranolol Analgesic Efficacy for Treating Post-surgical Pain After Laparoscopic Hemicolectomy[NCT02511483]Phase 210 participants (Actual)Interventional2015-05-18Terminated (stopped due to Difficulty with recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for propranolol and Nociceptive Pain

ArticleYear
Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation.
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:7

    Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dura Mater; Glucosides; Levetiracetam; Male; Medic

2018
Propranolol elicits cutaneous analgesia against skin nociceptive stimuli in rats.
    Neuroscience letters, 2012, Aug-30, Volume: 524, Issue:2

    Topics: Analgesics; Anesthetics, Local; Animals; Injections, Subcutaneous; Lidocaine; Male; Nociceptive Pain

2012