propranolol has been researched along with Neurofibromatosis 1 in 3 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Neurofibromatosis 1: An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Children with abdominal migraine were identified from a group of children with NF1, all of whom had been followed up for a minimum of 3 years." | 2.41 | Abdominal migraine in children with neurofibromatosis type 1: a case series and review of gastrointestinal involvement in NF1. ( Bousvaros, A; Heuschkel, R; Kim, S; Korf, B; Schneider, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Miraglia, E | 1 |
| Schiavetti, A | 1 |
| Varrasso, G | 1 |
| Celli, M | 1 |
| Calvieri, S | 1 |
| Giustini, S | 1 |
| Heuschkel, R | 1 |
| Kim, S | 1 |
| Korf, B | 1 |
| Schneider, G | 1 |
| Bousvaros, A | 1 |
| Müller-Wiefel, DE | 1 |
1 review available for propranolol and Neurofibromatosis 1
| Article | Year |
|---|---|
Abdominal migraine in children with neurofibromatosis type 1: a case series and review of gastrointestinal involvement in NF1.
Topics: Abdominal Pain; Adrenergic beta-Antagonists; Child; Child, Preschool; Female; Humans; Male; MEDLINE; | 2001 |
2 other studies available for propranolol and Neurofibromatosis 1
| Article | Year |
|---|---|
Effectiveness of oral propranolol in a patient with neurofibromatosis type 1 and infantile hemangiomas.
Topics: Hemangioma; Hemangioma, Capillary; Humans; Infant; Neurofibromatosis 1; Propranolol | 2021 |
[Renovascular hypertension in neurofibromatosis von Recklinghausen (author's transl)].
Topics: Aneurysm; Child; Dihydralazine; Headache; Humans; Hypertension, Renal; Male; Neurofibromatosis 1; Pr | 1978 |