Page last updated: 2024-11-03

propranolol and Nervous System Disorders

propranolol has been researched along with Nervous System Disorders in 30 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"The discovery of propranolol in 1964 and its introducing to the clinical practice has been essential for the progress in the diagnostics and therapy of cardiovascular diseases."4.83[Propranolol--a place in the modern therapy]. ( Olakowska, E; Olakowski, M, 2006)
"The tremor was coarse, irregular, and unrelated to proprioception loss, muscle weakness, or fatigue; it appeared to represent disease activity or an early sign of a new relapse."1.27Tremor as a feature of chronic relapsing and dysgammaglobulinemic polyneuropathies. Incidence and management. ( Dalakas, MC; Engel, WK; Teräväinen, H, 1984)
" Although drugs can ameliorate certain toxic effects, indiscriminate use of purported antidotes can have deleterious results."1.26Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review. ( Irwin, HA; Preskorn, SH, 1982)
"While headache was resistant to ergotamine preparations, prompt relief was obtained with propranolol hydrochloride, and adrenergic beta-receptor blocking agent."1.25Posttraumatic dysautonomic cephalalgia. Clinical observations and treatment. ( Dreyfus, PM; Vijayan, N, 1975)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199024 (80.00)18.7374
1990's1 (3.33)18.2507
2000's3 (10.00)29.6817
2010's1 (3.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Lanfranconi, S1
Scola, E1
Bertani, GA1
Zarino, B1
Pallini, R1
d'Alessandris, G1
Mazzon, E1
Marino, S1
Carriero, MR1
Scelzo, E1
Faragò, G1
Castori, M1
Fusco, C1
Petracca, A1
d'Agruma, L1
Tassi, L1
d'Orio, P1
Lampugnani, MG1
Nicolis, EB1
Vasamì, A1
Novelli, D1
Torri, V1
Meessen, JMTA1
Al-Shahi Salman, R1
Dejana, E1
Latini, R1
Kubo, Y1
Sangla, S1
Tranchant, C1
de Luis, DA1
Abad, L1
Aller, R1
González-Sagrado, M1
Dueñas, A1
Olakowska, E1
Olakowski, M1
Furberg, C1
Moses, JW1
Borer, JS1
Obukhov, GA1
Głuszcz-Zielińska, A1
Dalakas, MC1
Teräväinen, H1
Engel, WK1
Preskorn, SH1
Irwin, HA1
Thandroyen, FT1
Asmal, AC1
Bhagat, CI1
Dayal, B1
van Poeck, KJ1
Frandsen, PJ1
Mikkelsen, B1
Vijayan, N1
Dreyfus, PM1
Bergfeldt, BL1
Olofsson, BO1
Edhag, KO1
Yokoyama, M1
Tokue, A1
Tsukada, O1
Aso, Y1
Kerr, JH1
Travis, KW1
O'Rourke, RA1
Sims, JK1
Uhl, RR1
Nazarova, LN1
Petrenko, AD1
Kanarek, DJ1
Kaufman, B1
Zwi, S1
Lloyd-Mostyn, R1
Watkins, PJ1
Oram, S1
Conn, RD1
Dobrescu, DI1
Aigner, A1
Baumgartl, P1
Bolzano, K1
Raas, E1
Cherchi, A2
Lixi, M2
Raffo, M2
Porrazzo, G2
Bina, M1
Camoglio, E2
Verona, F1
Baszczyński, J1
Miyahara, M1
Iimura, O1
Abe, H1
Ueda, T1
Morikawa, A1
Davis, JN1
Frohlich, ED1
Tarazi, RC1
Dustan, HP1
Sassu, P1
Biddau, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treat_CCM Clinical Trial A Multicenter Randomized Clinical Trial on Propranolol in Familial Cerebral Cavernous Malformation[NCT03589014]Phase 271 participants (Actual)Interventional2018-04-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for propranolol and Nervous System Disorders

ArticleYear
[Carrier-mediated Transport of Cationic Drugs across the Blood-Tissue Barrier].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:10

    Topics: Angiogenesis Inhibitors; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Cation Tr

2015
[Writer's cramp].
    Revue neurologique, 2009, Volume: 165 Spec No 3

    Topics: Botulinum Toxins, Type A; Clonazepam; Combined Modality Therapy; Cumulative Trauma Disorders; Diagno

2009
[Levothyroxine poisoning: clinical manifestations and therapeutic management].
    Anales de medicina interna (Madrid, Spain : 1984), 2004, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Cardiovascular Diseases; Child; Cholestyramine Resi

2004
[Propranolol--a place in the modern therapy].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2006, Volume: 59, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Heart Diseases; Humans; Hyperthyroidism; Nervous System Diseases; Propr

2006
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca

1981
[Use of beta-adrenergic blockers in neurologic and psychiatric clinical practice].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Adrenergic beta-Antagonists; Alcoholism; Anti-Anxiety Agents; Cardiovascular Diseases; Humans; Hyper

1981

Trials

3 trials available for propranolol and Nervous System Disorders

ArticleYear
Propranolol for familial cerebral cavernous malformation (Treat_CCM): study protocol for a randomized controlled pilot trial.
    Trials, 2020, May-12, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Anxiety; Case-Control Studies; Depression; Disease Prog

2020
Propranolol in the treatment of disturbances of the autonomic nervous system.
    Current therapeutic research, clinical and experimental, 1971, Volume: 13, Issue:1

    Topics: Adult; Amobarbital; Atropa belladonna; Autonomic Nervous System; Clinical Trials as Topic; Ergot Alk

1971
Hyperdynamic beta-adrenergic circulatory state. Increased beta-receptor responsiveness.
    Archives of internal medicine, 1969, Volume: 123, Issue:1

    Topics: Adult; Autonomic Nervous System; Blood Circulation; Blood Pressure; Cardiac Output; Cardiovascular D

1969

Other Studies

21 other studies available for propranolol and Nervous System Disorders

ArticleYear
Adrenergic beta-blockade and electrocardiographical ST-T changes.
    Acta medica Scandinavica, 1967, Volume: 181, Issue:1

    Topics: Adolescent; Adult; Child; Diagnosis, Differential; Electrocardiography; Exercise Test; Humans; Middl

1967
[Use of propranolol and other beta-adrenolytic drugs in the treatment of nervous system diseases].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1984, Nov-15, Volume: 37, Issue:22

    Topics: Adrenergic beta-Antagonists; Drug Evaluation; Humans; Mental Disorders; Nervous System Diseases; Pro

1984
Tremor as a feature of chronic relapsing and dysgammaglobulinemic polyneuropathies. Incidence and management.
    Archives of neurology, 1984, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Azathioprine; Chronic Disease; Dysgammaglobulinemia; Humans; Hypergammaglobulinem

1984
Toxicity of tricyclic antidepressants--kinetics, mechanism, intervention: a review.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Child; Dose-Response Relationsh

1982
Autonomic neuropathy in non-insulin-dependent diabetes mellitus in the young.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jul-12, Volume: 58, Issue:2

    Topics: Adult; Atropine; Autonomic Nervous System; Blood Pressure; Diabetic Neuropathies; Electrocardiograph

1980
[Chronic recurrent headache without neurological abnormalities. Practice guidelines of the Netherlands Society of Neurology].
    Nederlands tijdschrift voor geneeskunde, 1999, Jun-05, Volume: 143, Issue:23

    Topics: Adult; Aged; Chronic Disease; Contraindications; Drug Interactions; Female; Guidelines as Topic; Hea

1999
[Beta-adrenergic hyperactivity. A new clinical syndrome?].
    Ugeskrift for laeger, 1978, Mar-06, Volume: 140, Issue:10

    Topics: Adult; Female; Humans; Isoproterenol; Nervous System Diseases; Propranolol; Receptors, Adrenergic; R

1978
Posttraumatic dysautonomic cephalalgia. Clinical observations and treatment.
    Archives of neurology, 1975, Volume: 32, Issue:10

    Topics: Adult; Autonomic Nervous System; Carotid Artery Injuries; Female; Headache; Humans; Male; Middle Age

1975
Electrophysiologic evaluation of the cardiac conduction system and its autonomic regulation in familial amyloid polyneuropathy.
    The American journal of cardiology, 1985, Oct-01, Volume: 56, Issue:10

    Topics: Amyloidosis; Atropine; Autonomic Nervous System; Heart Conduction System; Humans; Isoproterenol; Ner

1985
[Hyperdynamic beta-adrenergic circulatory state with markedly labile hypertension (author's transl)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1974, Volume: 65, Issue:11

    Topics: Blood Pressure; Female; Humans; Hypertension; Middle Aged; Nervous System Diseases; Propranolol; Rec

1974
Autonomic complications in a case of severe tetanus.
    The American journal of medicine, 1974, Volume: 57, Issue:2

    Topics: Aged; Blood Pressure; Central Venous Pressure; Curare; Electric Stimulation; Heart Rate; Humans; Hyp

1974
[Use of inderal for differentiating EKG changes induced by ischemic heart disease and autonomic disorders].
    Kardiologiia, 1972, Volume: 12, Issue:12

    Topics: Adult; Coronary Disease; Diagnosis, Differential; Electrocardiography; Female; Heart Diseases; Human

1972
Severe sympathetic hyperactivity associated with tetanus.
    Archives of internal medicine, 1973, Volume: 132, Issue:4

    Topics: Adult; Benzyl Compounds; Blood Pressure; Female; Guanidines; Heart Rate; Humans; Nervous System Dise

1973
Proceedings: Autonomic neuropathy and the heart in diabetes.
    British heart journal, 1974, Volume: 36, Issue:4

    Topics: Atropine; Autonomic Nervous System; Blood Pressure; Cardiac Output; Denervation; Diabetic Neuropathi

1974
Clinical usefulness of beta-adrenergic blocking agents.
    Postgraduate medicine, 1974, Volume: 55, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Cardiomyopathy, Hypert

1974
[Hemodynamic and phonocardiographic changes after propranolol in sympathotonia].
    Deutsche medizinische Wochenschrift (1946), 1970, Dec-25, Volume: 95, Issue:52

    Topics: Adolescent; Adult; Autonomic Nervous System; Blood Pressure; Cardiac Output; Dysautonomia, Familial;

1970
[On the effect of propranolol on the effort electrocardiogram in normal, hypersympathotonic, coronary and pericarditis patients].
    Bollettino della Societa italiana di cardiologia, 1967, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Coronary Disease; Electrocardiography; Female; Humans; Male; Middle Aged; Nervous

1967
[Effect of beta adrenergic blockade on the cardiovascular system in the state of sympathicotonia in children].
    Pediatria polska, 1968, Volume: 44, Issue:1

    Topics: Adolescent; Autonomic Nerve Block; Blood Pressure; Child; Electrocardiography; Heart Rate; Humans; N

1968
[A case of hyperdynamic beta-adrenergic circulatory state].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1968, Volume: 57, Issue:7

    Topics: Adolescent; Cardiovascular System; Humans; Male; Nervous System Diseases; Propranolol; Sympathetic N

1968
Increases beta-receptor responsiveness; central or peripheral?
    Archives of internal medicine, 1969, Volume: 123, Issue:1

    Topics: Autonomic Nervous System; Cardiovascular Diseases; Chemoreceptor Cells; Hypertension; Isoproterenol;

1969
[On the action of propranolol on the phases of cardiac dynamics in normal, myocardiosclerotic and hypersympathicotonic subjects].
    Bollettino della Societa italiana di cardiologia, 1966, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Heart; Heart Diseases; Hemodynamics; Humans; Male; Middle Aged; Nervous Sys

1966