propranolol has been researched along with Neovascularization, Optic Disc in 9 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propranolol can reduce the formation of abnormal retinal neovascularization in oxygen-induced retinopathy (OIR) models, and reduce leaking, tortuous, and abnormally expanding retinal blood vessels." | 8.31 | Propranolol ameliorates retinopathy of prematurity in mice by downregulating HIF-1α via the PI3K/Akt/ERK pathway. ( Ding, Y; Liu, L; Liu, Y; Su, S; Wang, Y; Yang, G; Zhang, J; Zou, P, 2023) |
| "Propranolol could effectively inhibit the formation of retinal neovascularization in mice; the eye drops was more effective than the IP injection." | 7.83 | [Effects of propranolol on oxygen-induced retinal neovascularization in mouse]. ( Huang, X; Wang, Y; Yang, G; Yang, Z; Zhang, J, 2016) |
| "Propranolol can reduce the formation of abnormal retinal neovascularization in oxygen-induced retinopathy (OIR) models, and reduce leaking, tortuous, and abnormally expanding retinal blood vessels." | 4.31 | Propranolol ameliorates retinopathy of prematurity in mice by downregulating HIF-1α via the PI3K/Akt/ERK pathway. ( Ding, Y; Liu, L; Liu, Y; Su, S; Wang, Y; Yang, G; Zhang, J; Zou, P, 2023) |
| "Propranolol could effectively inhibit the formation of retinal neovascularization in mice; the eye drops was more effective than the IP injection." | 3.83 | [Effects of propranolol on oxygen-induced retinal neovascularization in mouse]. ( Huang, X; Wang, Y; Yang, G; Yang, Z; Zhang, J, 2016) |
| " Propranolol, a nonselective β-adrenergic receptor blocker, was reported to protect against pathologic retinal neovascularization in a mouse model of oxygen-induced retinopathy (OIR)." | 3.78 | Propranolol inhibition of β-adrenergic receptor does not suppress pathologic neovascularization in oxygen-induced retinopathy. ( Chen, J; Hatton, CJ; Hellstrom, A; Hurst, CG; Joyal, JS; Juan, AM; Pei, DT; Smith, LE; Stahl, A; Xu, D, 2012) |
| "Propranolol was administered subcutaneously and picropodophyllin (PPP) intraperitoneally." | 1.37 | Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade. ( Bagnoli, P; Cammalleri, M; Dal Monte, M; Filippi, L; Fiorini, P; Fortunato, P; la Marca, G; Martini, D; Ristori, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Su, S | 1 |
| Zou, P | 1 |
| Yang, G | 2 |
| Wang, Y | 2 |
| Liu, L | 1 |
| Liu, Y | 1 |
| Zhang, J | 2 |
| Ding, Y | 1 |
| Yun, JH | 1 |
| Koh, YJ | 1 |
| Jeong, HS | 1 |
| Lee, DH | 1 |
| Lee, EH | 1 |
| Cho, CH | 1 |
| Dal Monte, M | 3 |
| Casini, G | 1 |
| la Marca, G | 2 |
| Isacchi, B | 1 |
| Filippi, L | 3 |
| Bagnoli, P | 3 |
| Huang, X | 1 |
| Yang, Z | 1 |
| Korkmaz, L | 1 |
| Baştuğ, O | 1 |
| Ozdemir, A | 1 |
| Korkut, S | 1 |
| Karaca, C | 1 |
| Akin, MA | 1 |
| Gunes, T | 1 |
| Kurtoglu, S | 1 |
| Ozturk, MA | 1 |
| Ristori, C | 1 |
| Martini, D | 1 |
| Cammalleri, M | 1 |
| Fortunato, P | 1 |
| Fiorini, P | 1 |
| Chen, J | 2 |
| Joyal, JS | 1 |
| Hatton, CJ | 1 |
| Juan, AM | 1 |
| Pei, DT | 1 |
| Hurst, CG | 1 |
| Xu, D | 1 |
| Stahl, A | 1 |
| Hellstrom, A | 2 |
| Smith, LE | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Propranolol Eye Drops in Newborns With Retinopathy of Premature (DROP-PROP)[NCT02014454] | Phase 2 | 23 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Safety and Efficacy of Propranolol 0.2% Eye Drops in Treating Newborn With Retinopathy of Premature: A Pilot Study (DROP-ROP-0.2%)[NCT02504944] | Phase 2 | 98 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| Safety and Efficacy of Propranolol Treatment in Newborns With Retinopathy of Prematurity:a Prospective Cohort Study[NCT03038295] | Phase 2 | 100 participants (Anticipated) | Interventional | 2017-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for propranolol and Neovascularization, Optic Disc
| Article | Year |
|---|---|
Propranolol ameliorates retinopathy of prematurity in mice by downregulating HIF-1α via the PI3K/Akt/ERK pathway.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Humans; Infant, Newborn; MAP Kinase Signaling Sy | 2023 |
Propranolol increases vascular permeability through pericyte apoptosis and exacerbates oxygen-induced retinopathy.
Topics: Animals; Animals, Newborn; Apoptosis; Capillary Permeability; Coculture Techniques; Disease Models, | 2018 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
Eye drop propranolol administration promotes the recovery of oxygen-induced retinopathy in mice.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Infa | 2013 |
[Effects of propranolol on oxygen-induced retinal neovascularization in mouse].
Topics: Animals; Dextrans; Disease Models, Animal; Endothelial Cells; Fluorescein-5-isothiocyanate; Injectio | 2016 |
The Efficacy of Propranolol in Retinopathy of Prematurity and its Correlation with the Platelet Mass Index.
Topics: Adrenergic beta-Antagonists; Blood Platelets; Female; Gestational Age; Humans; Infant; Infant, Newbo | 2017 |
Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade.
Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Animals; Animals, Newborn; Blood-Retinal Barri | 2011 |
Propranolol inhibition of β-adrenergic receptor does not suppress pathologic neovascularization in oxygen-induced retinopathy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angiopoietin-1; Angiopoietin-2; Animals; Animals, | 2012 |
Different efficacy of propranolol in mice with oxygen-induced retinopathy: could differential effects of propranolol be related to differences in mouse strains?
Topics: Adrenergic beta-Antagonists; Animals; Humans; Mice; Propranolol; Retinal Neovascularization; Retinop | 2012 |
Author response: Different efficacy of propranolol in mice with oxygen-induced retinopathy: could differential effects of propranolol be related to differences in mouse strains?
Topics: Adrenergic beta-Antagonists; Animals; Humans; Mice; Propranolol; Retinal Neovascularization; Retinop | 2012 |