propranolol has been researched along with Neoplasm Metastasis in 20 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the effect of propranolol, a non-selective beta-blocker on overall survival (OS) in unresectable/metastatic hepatocellular carcinoma (HCC) and on recurrence-free survival (RFS) in resectable, curable HCC." | 7.91 | The effect of propranolol on the prognosis of hepatocellular carcinoma: A nationwide population-based study. ( Chang, PY; Chang, WC; Chien, WC; Chung, CH; Dai, MS; Ho, CL; Lin, CS; Lin, HH, 2019) |
| " In this study, we investigated the effect of propranolol, a non-selective beta-blocker on overall survival (OS) in unresectable/metastatic hepatocellular carcinoma (HCC) and on recurrence-free survival (RFS) in resectable, curable HCC." | 3.91 | The effect of propranolol on the prognosis of hepatocellular carcinoma: A nationwide population-based study. ( Chang, PY; Chang, WC; Chien, WC; Chung, CH; Dai, MS; Ho, CL; Lin, CS; Lin, HH, 2019) |
| "Different pharmacologic drugs (isadrin, obsidan, phentolamine) changing adrenergic processes are shown to have different effect on the growth and development of lung metastases." | 3.67 | [Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes]. ( Balitskiĭ, KP; Riabukha, VN; Smelkova, MI; Veksler, IG, 1984) |
| "However, β -adrenergic action in breast cancer is controversial." | 1.46 | The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line. ( Bruzzone, A; Entschladen, F; Gargiulo, L; Lüthy, IA; Piñero, CP; Rivero, EM; Zänker, K, 2017) |
| "Propranolol treatment delayed primary tumor growth and metastases development in MT/Ret mice." | 1.43 | Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma. ( Bod, L; Jean Wrobel, L; Kato, M; Le Gal, FA; Lengagne, R; Prévost-Blondel, A, 2016) |
| "Furthermore, we report that breast cancer cell migration is decreased by the FDA-approved β-blocker, propranolol." | 1.42 | β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells. ( Lorimer, E; Tyburski, MD; Williams, CL; Wilson, JM, 2015) |
| "When tumors reached 100 mm, mice were treated with CpG-C/vehicle, and 24 hours later the tumor was excised along with P+E/vehicle treatment." | 1.37 | Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses. ( Ben-Eliyahu, S; Benish, M; Goldfarb, Y; Levi, B; Melamed, R; Sorski, L, 2011) |
| "Propranolol users were significantly less likely to present with a T4 (odds ratio [OR], 0." | 1.37 | Beta blockers and breast cancer mortality: a population- based study. ( Barron, TI; Bennett, K; Connolly, RM; Sharp, L; Visvanathan, K, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rivero, EM | 1 |
| Piñero, CP | 1 |
| Gargiulo, L | 1 |
| Entschladen, F | 2 |
| Zänker, K | 1 |
| Bruzzone, A | 1 |
| Lüthy, IA | 1 |
| Chang, PY | 1 |
| Chung, CH | 1 |
| Chang, WC | 1 |
| Lin, CS | 1 |
| Lin, HH | 1 |
| Dai, MS | 1 |
| Ho, CL | 1 |
| Chien, WC | 1 |
| Barbieri, A | 1 |
| Bimonte, S | 1 |
| Palma, G | 1 |
| Luciano, A | 1 |
| Rea, D | 1 |
| Giudice, A | 1 |
| Scognamiglio, G | 1 |
| La Mantia, E | 1 |
| Franco, R | 1 |
| Perdonà, S | 1 |
| De Cobelli, O | 1 |
| Ferro, M | 1 |
| Zappavigna, S | 1 |
| Stiuso, P | 1 |
| Caraglia, M | 1 |
| Arra, C | 1 |
| Wilson, JM | 1 |
| Lorimer, E | 1 |
| Tyburski, MD | 1 |
| Williams, CL | 1 |
| Duff, S | 1 |
| Connolly, C | 1 |
| Buggy, DJ | 1 |
| Jean Wrobel, L | 1 |
| Bod, L | 1 |
| Lengagne, R | 1 |
| Kato, M | 1 |
| Prévost-Blondel, A | 1 |
| Le Gal, FA | 1 |
| Glasner, A | 1 |
| Avraham, R | 1 |
| Rosenne, E | 1 |
| Benish, M | 2 |
| Zmora, O | 1 |
| Shemer, S | 1 |
| Meiboom, H | 1 |
| Ben-Eliyahu, S | 2 |
| Schuller, HM | 1 |
| Goldfarb, Y | 1 |
| Sorski, L | 1 |
| Levi, B | 1 |
| Melamed, R | 1 |
| Ganz, PA | 1 |
| Cole, SW | 1 |
| Barron, TI | 1 |
| Connolly, RM | 1 |
| Sharp, L | 1 |
| Bennett, K | 1 |
| Visvanathan, K | 1 |
| Strell, C | 1 |
| Niggemann, B | 1 |
| Voss, MJ | 1 |
| Powe, DG | 1 |
| Zänker, KS | 1 |
| Balitskiĭ, KP | 2 |
| Veksler, IG | 1 |
| Riabukha, VN | 1 |
| Smelkova, MI | 1 |
| Shaklai, M | 1 |
| Aderka, D | 1 |
| Blum, I | 1 |
| Laron, Z | 1 |
| Asherov, J | 1 |
| Doron, M | 1 |
| Atsmon, A | 1 |
| Pinkhas, J | 1 |
| van den Broek, PJ | 1 |
| de Graeff, J | 1 |
| Wade, H | 1 |
| Scharf, Y | 1 |
| Nahir, AM | 1 |
| Better, OS | 1 |
| Koten, A | 1 |
| Arieh, YB | 1 |
| Gellei, B | 1 |
| Harrison, TS | 1 |
| Freier, DT | 1 |
| Cohen, EL | 1 |
| Storstein, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Perioperative Pain Management for Laparoscopic Surgery Due to Colon Cancer Using the Ultrasound-guided Transmuscular Quadratus Lumborum Block. A Double Blind, Randomized, Placebo Controlled Trial.[NCT03570541] | Phase 4 | 69 participants (Actual) | Interventional | 2018-06-28 | Completed | ||
| Anesthesia and Immunological and Oxidative Stress in Relation to Abdominal Cancer Surgery[NCT03974984] | 0 participants (Actual) | Observational | 2020-06-04 | Withdrawn (stopped due to Not feasable due to logistics) | |||
| Impact of Novel Thoracic Wall Blocks With Dexmetomidine on Inflammatory Markers Following Breast Cancer Surgery[NCT04860115] | 120 participants (Anticipated) | Interventional | 2021-11-01 | Not yet recruiting | |||
| Melablock: A Multicentre Randomized, Double---blinded and Placebo---controlled Clinical Trial on the Efficacy and Safety of Once Daily Propranolol 80 mg Retard for the Prevention of Cutaneous Malignant Melanoma Recurrence[NCT02962947] | Phase 2/Phase 3 | 546 participants (Anticipated) | Interventional | 2017-06-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propranolol and Neoplasm Metastasis
| Article | Year |
|---|---|
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
Adrenergic, Inflammatory, and Immune Function in the Setting of Oncological Surgery: Their Effects on Cancer Progression and the Role of the Anesthetic Technique in their Modulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Anesthetics; Animals; Disease Models, Animal; Disease Progr | 2016 |
19 other studies available for propranolol and Neoplasm Metastasis
| Article | Year |
|---|---|
The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line.
Topics: Adrenergic Agonists; Albuterol; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pro | 2017 |
The effect of propranolol on the prognosis of hepatocellular carcinoma: A nationwide population-based study.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Disease-Free Survival; Female; Humans; Liver Neoplasms; Male | 2019 |
The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo.
Topics: Animals; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Gene Expression Regulati | 2015 |
β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Aminopyridines; Breast Neoplasms; | 2015 |
Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Lymphocytes, Tumor-Infiltrating; Melanoma, Exper | 2016 |
Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor.
Topics: Adrenergic beta-Antagonists; Amputation, Surgical; Animals; Antineoplastic Combined Chemotherapy Pro | 2010 |
Beta-adrenergic signaling, a novel target for cancer therapy?
Topics: Adrenergic beta-Antagonists; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Female; Humans; Hyp | 2010 |
Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses.
Topics: Analysis of Variance; Animals; Chemotherapy, Adjuvant; Disease Models, Animal; Etodolac; Female; Imm | 2011 |
Expanding our therapeutic options: Beta blockers for breast cancer?
Topics: Adrenergic beta-Antagonists; Atenolol; Breast Neoplasms; Diabetes Complications; Disease-Free Surviv | 2011 |
Beta blockers and breast cancer mortality: a population- based study.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Breast Neoplasms; Disease Progression; Female; Humans; | 2011 |
Norepinephrine promotes the β1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROα release.
Topics: Adrenergic beta-Antagonists; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Chemokine CXCL1; End | 2012 |
[Methods of directly influencing the metastatic process].
Topics: Animals; Growth Inhibitors; Interferons; Isoproterenol; Macrophages; Mice; Mice, Inbred Strains; Neo | 1984 |
[Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Therapy, Combin | 1984 |
Suppression of hypoglycemic attacks and insulin release by propranolol in a patient with metastatic malignant insulinoma.
Topics: Adenoma, Islet Cell; Female; Humans; Hypoglycemia; Insulin; Insulin Secretion; Middle Aged; Neoplasm | 1977 |
Prolonged survival in a patient with pulmonary metastases of a malignant pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Middle Ag | 1978 |
The surgical management of thyroid disorders.
Topics: Adenocarcinoma; Age Factors; Calcitonin; Carbimazole; Goiter; Humans; Hyperthyroidism; Neoplasm Meta | 1972 |
Prolonged survival in malignant pheochromocytoma of the organ of Zuckerkandl with pharmacological treatment.
Topics: Adrenal Gland Neoplasms; Adult; Chromaffin System; Cyclophosphamide; Female; Follow-Up Studies; Huma | 1973 |
Proceedings: Recurrent pheochromocytoma.
Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Adult; Child; Epinephrine; Female; Hormone | 1974 |
Hemodynamic studies in primary myocardial disease.
Topics: Adolescent; Adult; Amyloidosis; Angiography; Aortic Valve Stenosis; Beriberi; Blood Pressure; Carcin | 1967 |