propranolol has been researched along with Multiple Sclerosis in 4 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effect of long-term administration of propranolol hydrochloride and isoniazid and the acute action of ethyl alcohol on cerebellar tremor in patients with multiple sclerosis and primary cerebellar degeneration in a placebo-controlled double-blind crossover test." | 5.05 | Pharmacologic trials in the treatment of cerebellar tremor. ( Koller, WC, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilipović, I | 1 |
| Stojić-Vukanić, Z | 1 |
| Leposavić, G | 1 |
| Koller, WC | 2 |
| Biary, N | 1 |
| Kreiss, Y | 1 |
| Cohen, O | 1 |
| Pras, E | 1 |
| Achiron, A | 1 |
1 review available for propranolol and Multiple Sclerosis
| Article | Year |
|---|---|
Adrenoceptors as potential target for add-on immunomodulatory therapy in multiple sclerosis.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Epstein-Barr Virus Infections; Female; Herpesv | 2023 |
2 trials available for propranolol and Multiple Sclerosis
| Article | Year |
|---|---|
Pharmacologic trials in the treatment of cerebellar tremor.
Topics: Adult; Cerebellar Diseases; Clinical Trials as Topic; Double-Blind Method; Ethanol; Humans; Isoniazi | 1984 |
Effect of alcohol on tremors: comparison with propranolol.
Topics: Adult; Cerebellar Diseases; Ethanol; Humans; Male; Middle Aged; Multiple Sclerosis; Parkinson Diseas | 1984 |
1 other study available for propranolol and Multiple Sclerosis
| Article | Year |
|---|---|
Subacute thyroiditis in a patient with MS treated with interferon beta-1a.
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Human | 1999 |