propranolol has been researched along with Malaria in 9 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of the erythrocyte stage of malaria infection on hepatic glucuronidation, biliary excretion and oxidation processes was investigated using harmol, salbutamol, taurocholate and propranolol." | 3.68 | Malaria infection impairs glucuronidation and biliary excretion by the isolated perfused rat liver. ( Ghabrial, H; Mihaly, GW; Morgan, DJ; Murdoch, RT; Smallwood, RA, 1991) |
| " Previously described THQ PFTIs had limitations of poor oral bioavailability and rapid clearance from the circulation of rodents." | 1.34 | Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. ( Ankala, S; Barrett, LK; Bauer, KD; Bendale, P; Buckner, FS; Chakrabarti, D; Floyd, D; Gelb, MH; Hamilton, AD; Hornéy, C; Hucke, O; Lombardo, LJ; Nallan, L; Rivas, KL; Smart, BP; Strickland, C; Van Voorhis, WC; Verlinde, CL; Williams, DK; Yokoyama, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Voorhis, WC | 1 |
| Rivas, KL | 1 |
| Bendale, P | 1 |
| Nallan, L | 1 |
| Hornéy, C | 1 |
| Barrett, LK | 1 |
| Bauer, KD | 1 |
| Smart, BP | 1 |
| Ankala, S | 1 |
| Hucke, O | 1 |
| Verlinde, CL | 1 |
| Chakrabarti, D | 1 |
| Strickland, C | 1 |
| Yokoyama, K | 1 |
| Buckner, FS | 1 |
| Hamilton, AD | 1 |
| Williams, DK | 1 |
| Lombardo, LJ | 1 |
| Floyd, D | 1 |
| Gelb, MH | 1 |
| Singh, K | 1 |
| Okombo, J | 2 |
| Brunschwig, C | 1 |
| Ndubi, F | 1 |
| Barnard, L | 1 |
| Wilkinson, C | 1 |
| Njogu, PM | 1 |
| Njoroge, M | 1 |
| Laing, L | 1 |
| Machado, M | 1 |
| Prudêncio, M | 1 |
| Reader, J | 1 |
| Botha, M | 1 |
| Nondaba, S | 1 |
| Birkholtz, LM | 1 |
| Lauterbach, S | 1 |
| Churchyard, A | 1 |
| Coetzer, TL | 1 |
| Burrows, JN | 1 |
| Yeates, C | 1 |
| Denti, P | 1 |
| Wiesner, L | 2 |
| Egan, TJ | 2 |
| Wittlin, S | 1 |
| Chibale, K | 2 |
| Joshi, MC | 1 |
| Nsumiwa, S | 1 |
| Ndove, J | 1 |
| Taylor, D | 1 |
| Hunter, R | 1 |
| Shahabi, S | 1 |
| Mohammadzadeh Hajipirloo, H | 1 |
| Keramati, A | 1 |
| Hazrati Tappeh, K | 1 |
| Bozorgomid, A | 1 |
| Harrison, T | 2 |
| Samuel, BU | 1 |
| Akompong, T | 1 |
| Hamm, H | 1 |
| Mohandas, N | 2 |
| Lomasney, JW | 2 |
| Haldar, K | 2 |
| Murphy, SC | 1 |
| Hamm, HE | 1 |
| Murdoch, RT | 1 |
| Ghabrial, H | 1 |
| Mihaly, GW | 1 |
| Morgan, DJ | 1 |
| Smallwood, RA | 1 |
| Khare, S | 1 |
| Ghatak, S | 1 |
| Shoemaker, JP | 1 |
| McAllister, RG | 1 |
| Selby, JB | 1 |
| Hoffman, RV | 1 |
9 other studies available for propranolol and Malaria
| Article | Year |
|---|---|
Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase.
Topics: Animals; Antimalarials; Bile Ducts; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray | 2007 |
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.
Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; | 2017 |
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeab | 2017 |
Evaluation of the adjuvant activity of propranolol, a Beta-adrenergic receptor antagonist, on efficacy of a malaria vaccine model in BALB/c mice.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Animals; Antibodies, Protozoan; Humans; Immunog | 2014 |
Erythrocyte G protein-coupled receptor signaling in malarial infection.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonist | 2003 |
Erythrocyte G protein as a novel target for malarial chemotherapy.
Topics: Adrenergic beta-Antagonists; Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Drug Therap | 2006 |
Malaria infection impairs glucuronidation and biliary excretion by the isolated perfused rat liver.
Topics: Albuterol; Animals; Bile; Erythrocytes; Glucuronates; Harmine; Liver; Malaria; Male; Metabolic Clear | 1991 |
Cyclic AMP level in red blood cells of Plasmodium berghei-infected Mastomys natalensis.
Topics: Animals; Cyclic AMP; Erythrocytes; Isoproterenol; Malaria; Male; Muridae; Plasmodium berghei; Propra | 1991 |
Effect of hypothyroidism on parasitemia and survival in rodent malaria.
Topics: Animals; Drug Resistance, Microbial; Erythrocyte Count; Female; Hypothyroidism; Iodine Radioisotopes | 1974 |