propranolol has been researched along with Lung Neoplasms in 26 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary hemangioma is a rare benign tumor of the lungs." | 5.40 | Successful treatment of pulmonary hemangioma with propranolol. ( Akyüz, C; Emiralioğlu, N; Ersöz, DD; Kiper, N; Oğuz, B; Özçelik, U; Yalçın, B; Yalçın, E, 2014) |
| "Different pharmacologic drugs (isadrin, obsidan, phentolamine) changing adrenergic processes are shown to have different effect on the growth and development of lung metastases." | 3.67 | [Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes]. ( Balitskiĭ, KP; Riabukha, VN; Smelkova, MI; Veksler, IG, 1984) |
| "Propranolol (PRO) has been recently discovered to possess anti-tumorigenic effects in cancer patients." | 1.91 | Anti-proliferative effects of beta-blocker propranolol on human lung cancer and noncancer cells. ( Terzi, MY; Urhan-Kucuk, M, 2023) |
| "However, β -adrenergic action in breast cancer is controversial." | 1.46 | The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line. ( Bruzzone, A; Entschladen, F; Gargiulo, L; Lüthy, IA; Piñero, CP; Rivero, EM; Zänker, K, 2017) |
| "Pulmonary hemangioma is a rare benign tumor of the lungs." | 1.40 | Successful treatment of pulmonary hemangioma with propranolol. ( Akyüz, C; Emiralioğlu, N; Ersöz, DD; Kiper, N; Oğuz, B; Özçelik, U; Yalçın, B; Yalçın, E, 2014) |
| "Nicotine-treated NSCLC cells showed significant induction of the α7nAChR and α4nAChR, along with significant inductions of p-CREB and p-ERK1/2 accompanied by increases in the stress neurotransmitter noradrenaline, which in turn led to the observed increase in DNA synthesis and cell proliferation." | 1.38 | Cooperative regulation of non-small cell lung carcinoma by nicotinic and beta-adrenergic receptors: a novel target for intervention. ( Al-Wadei, HA; Al-Wadei, MH; Schuller, HM, 2012) |
| "Lung cancer has a strong etiologic association with cigarette smoking." | 1.35 | Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation. ( Deng, X; Wang, T; Xin, M; Zhang, Y; Zhao, J, 2009) |
| "Lung cancer is the leading cause of cancer death in industrialized countries." | 1.31 | Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters. ( Porter, B; Riechert, A; Schuller, HM, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Sidorova, M | 1 |
| Petrikaitė, V | 1 |
| Ray, R | 1 |
| Al Khashali, H | 1 |
| Haddad, B | 1 |
| Wareham, J | 1 |
| Coleman, KL | 1 |
| Alomari, D | 1 |
| Ranzenberger, R | 1 |
| Guthrie, J | 1 |
| Heyl, D | 1 |
| Evans, HG | 1 |
| Terzi, MY | 1 |
| Urhan-Kucuk, M | 1 |
| Rivero, EM | 1 |
| Piñero, CP | 1 |
| Gargiulo, L | 1 |
| Entschladen, F | 1 |
| Zänker, K | 1 |
| Bruzzone, A | 1 |
| Lüthy, IA | 1 |
| Wang, H | 1 |
| Gomez, DR | 1 |
| Liao, Z | 1 |
| Emiralioğlu, N | 1 |
| Oğuz, B | 1 |
| Akyüz, C | 1 |
| Yalçın, B | 1 |
| Kiper, N | 1 |
| Ersöz, DD | 1 |
| Yalçın, E | 1 |
| Özçelik, U | 1 |
| Zhang, J | 1 |
| Deng, YT | 1 |
| Liu, J | 1 |
| Wang, YQ | 1 |
| Yi, TW | 1 |
| Huang, BY | 1 |
| He, SS | 1 |
| Zheng, B | 1 |
| Jiang, Y | 1 |
| Zhao, J | 1 |
| Xin, M | 1 |
| Wang, T | 1 |
| Zhang, Y | 1 |
| Deng, X | 1 |
| Friedman, GD | 1 |
| Udaltsova, N | 1 |
| Habel, LA | 1 |
| Ozeki, M | 1 |
| Fukao, T | 1 |
| Kondo, N | 1 |
| Al-Wadei, HA | 1 |
| Al-Wadei, MH | 1 |
| Schuller, HM | 3 |
| Veksler, IG | 1 |
| Riabukha, VN | 1 |
| Smelkova, MI | 1 |
| Balitskiĭ, KP | 1 |
| Cates, LA | 1 |
| Li, VS | 1 |
| Powell, DR | 1 |
| van der Helm, D | 1 |
| Feyns, LV | 1 |
| Beisler, JA | 1 |
| Driscoll, JS | 1 |
| Adamson, RA | 1 |
| Hofmockel, G | 1 |
| Heimbach, D | 1 |
| Bussen, D | 1 |
| Reincke, M | 1 |
| Frohmüller, HG | 1 |
| Simonsen, L | 1 |
| Bülow, J | 1 |
| Tuxen, C | 1 |
| Christensen, NJ | 1 |
| Shakhar, G | 1 |
| Ben-Eliyahu, S | 1 |
| Finney, RE | 1 |
| Nudelman, E | 1 |
| White, T | 1 |
| Bursten, S | 1 |
| Klein, P | 1 |
| Leer, LL | 1 |
| Wang, N | 1 |
| Waggoner, D | 1 |
| Singer, JW | 1 |
| Lewis, RA | 1 |
| Porter, B | 1 |
| Riechert, A | 1 |
| Chai, MQ | 1 |
| Chen, JS | 1 |
| Zhao, S | 1 |
| Song, JG | 1 |
| van den Broek, PJ | 1 |
| de Graeff, J | 1 |
| Reardon, G | 1 |
| Collins, AJ | 1 |
| Bacon, PA | 1 |
| Cole, B | 1 |
| Pigman, EC | 1 |
| Palmer, JB | 1 |
| Cuss, FM | 1 |
| Barnes, PJ | 1 |
| Harrison, TS | 1 |
| Freier, DT | 1 |
| Cohen, EL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Melablock: A Multicentre Randomized, Double---blinded and Placebo---controlled Clinical Trial on the Efficacy and Safety of Once Daily Propranolol 80 mg Retard for the Prevention of Cutaneous Malignant Melanoma Recurrence[NCT02962947] | Phase 2/Phase 3 | 546 participants (Anticipated) | Interventional | 2017-06-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for propranolol and Lung Neoplasms
| Article | Year |
|---|---|
Glucose-induced thermogenesis in patients with small cell lung carcinoma. The effect of acute beta-adrenergic inhibition.
Topics: Aged; Blood Flow Velocity; Blood Glucose; Blood Pressure; Carcinoma, Small Cell; Catecholamines; Ene | 1994 |
25 other studies available for propranolol and Lung Neoplasms
| Article | Year |
|---|---|
The Effect of Beta Adrenoreceptor Blockers on Viability and Cell Colony Formation of Non-Small Cell Lung Cancer Cell Lines A549 and H1299.
Topics: Adrenergic beta-Antagonists; Carcinoma, Non-Small-Cell Lung; Cell Line; Humans; Lung Neoplasms; Prop | 2022 |
Regulation of Cisplatin Resistance in Lung Cancer Cells by Nicotine, BDNF, and a β-Adrenergic Receptor Blocker.
Topics: Adrenergic Antagonists; Brain-Derived Neurotrophic Factor; Carcinoma, Non-Small-Cell Lung; Cell Line | 2022 |
Anti-proliferative effects of beta-blocker propranolol on human lung cancer and noncancer cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Propranolol | 2023 |
The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line.
Topics: Adrenergic Agonists; Albuterol; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pro | 2017 |
β-Blockers and metastasis in non-small-cell lung cancer.
Topics: Adrenergic beta-Antagonists; Animals; Carcinoma, Non-Small-Cell Lung; gamma-Aminobutyric Acid; Human | 2013 |
Successful treatment of pulmonary hemangioma with propranolol.
Topics: Adrenergic beta-Antagonists; Female; Hemangioma; Humans; Infant; Lung Neoplasms; Propranolol; Radiog | 2014 |
Norepinephrine induced epithelial-mesenchymal transition in HT-29 and A549 cells in vitro.
Topics: Adrenergic beta-Antagonists; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Cyclic AMP; Epit | 2016 |
Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activation; Flavonoids | 2009 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Meto | 2011 |
Propranolol for intractable diffuse lymphangiomatosis.
Topics: Adolescent; Chylothorax; Humans; Lung; Lung Neoplasms; Lymphangioma; Male; Propranolol; Radiography; | 2011 |
Cooperative regulation of non-small cell lung carcinoma by nicotinic and beta-adrenergic receptors: a novel target for intervention.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Lin | 2012 |
[Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Therapy, Combin | 1984 |
Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives.
Topics: Animals; Diethylstilbestrol; Dosage Forms; Ficusin; Leukemia, Experimental; Lung Neoplasms; Mammary | 1984 |
Synthesis of propranolol mustard as a possible lung-specific antitumor agent.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Lung Neoplasms; Mice; Neoplasms, Expe | 1980 |
[Surgical interventions of the adrenal gland. Diagnosis and results of treatment].
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; | 1994 |
In vivo beta-adrenergic stimulation suppresses natural killer activity and compromises resistance to tumor metastasis in rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood-Brain Barrier; Cytotoxicity, I | 1998 |
Pharmacological inhibition of phosphatidylcholine biosynthesis is associated with induction of phosphatidylinositol accumulation and cytolysis of neoplastic cell lines.
Topics: Adrenergic beta-Antagonists; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Survival; Cho | 2000 |
Beta-adrenergic modulation of NNK-induced lung carcinogenesis in hamsters.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carcinogens; Criceti | 2000 |
Propranolol increases phosphatidic acid level via activation of phospholipase D.
Topics: Enzyme Activation; Humans; Lung Neoplasms; Phosphatidic Acids; Phospholipase D; Propranolol; Protein | 2001 |
Prolonged survival in a patient with pulmonary metastases of a malignant pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Middle Ag | 1978 |
The effect of adrenergic blockade in hypertrophic pulmonary osteoarthropathy (HPOA).
Topics: Female; Humans; Lung Neoplasms; Middle Aged; Osteoarthropathy, Secondary Hypertrophic; Phenoxybenzam | 1976 |
Regulation of cell proliferation by beta-adrenergic receptors in a human lung adenocarcinoma cell line.
Topics: Adenocarcinoma; Cell Division; Cell Line; Hexamethonium; Hexamethonium Compounds; Humans; Lung Neopl | 1989 |
Chronic beta-blocker therapy complicating the presentation of cardiac tamponade of malignancy.
Topics: Cardiac Tamponade; Dyspnea; Heart Neoplasms; Humans; Hypertension; Lung Neoplasms; Male; Middle Aged | 1989 |
VIP and PHM and their role in nonadrenergic inhibitory responses in isolated human airways.
Topics: Bronchi; Humans; In Vitro Techniques; Indomethacin; Lung; Lung Neoplasms; Muscle, Smooth; Peptide PH | 1986 |
Proceedings: Recurrent pheochromocytoma.
Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Adult; Child; Epinephrine; Female; Hormone | 1974 |