Page last updated: 2024-11-03

propranolol and Liver Steatosis

propranolol has been researched along with Liver Steatosis in 4 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"To quantify the various components of splanchnic free fatty acid and very-low-density lipoprotein-triacylglycerol (VLDL-TAG) metabolism in order to gain insight into the mechanisms responsible for the development of fatty liver in severely burned patients, and to determine if decreasing free fatty acid availability by use of propranolol could potentially reduce hepatic fatty acid accumulation."3.71Propranolol decreases splanchnic triacylglycerol storage in burn patients receiving a high-carbohydrate diet. ( Herndon, DN; Irtun, O; Morio, B; Wolfe, RR, 2002)
" Studies were undertaken using an in situ-perfused rat liver and multiple indicator dilution, and outflow data were analyzed with a physiologically based organ pharmacokinetic model."1.37Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. ( Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Thorling, CA; Zhang, Q, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, P1
Robertson, TA1
Thorling, CA1
Zhang, Q1
Fletcher, LM1
Crawford, DH1
Roberts, MS1
McKee, C1
Soeda, J1
Asilmaz, E1
Sigalla, B1
Morgan, M1
Sinelli, N1
Roskams, T1
Oben, JA1
Walldorf, J1
Hillebrand, C1
Aurich, H1
Stock, P1
Hempel, M1
Ebensing, S1
Fleig, WE1
Seufferlein, T1
Dollinger, MM1
Christ, B1
Morio, B1
Irtun, O1
Herndon, DN1
Wolfe, RR1

Other Studies

4 other studies available for propranolol and Liver Steatosis

ArticleYear
Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cations; Cytochrome P-450

2011
Propranolol, a β-adrenoceptor antagonist, worsens liver injury in a model of non-alcoholic steatohepatitis.
    Biochemical and biophysical research communications, 2013, Aug-09, Volume: 437, Issue:4

    Topics: Adrenergic beta-Antagonists; Alanine Transaminase; Animals; Apoptosis; Choline; Culture Media; Disea

2013
Propranolol impairs liver regeneration after partial hepatectomy in C57Bl/6-mice by transient attenuation of hepatic lipid accumulation and increased apoptosis.
    Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Cell Cycle; Fatty Liver; G1 Phase; Hepatectomy; Hepatocytes;

2010
Propranolol decreases splanchnic triacylglycerol storage in burn patients receiving a high-carbohydrate diet.
    Annals of surgery, 2002, Volume: 236, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Burns; Child; Child, Preschool; Dietary Carbohydrate

2002