propranolol has been researched along with Left Ventricular Hypertrophy in 26 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To establish whether propranolol can reverse left ventricular hypertrophy in hypertensive rats." | 7.73 | Reversal of left ventricular hypertrophy by propranolol in hypertensive rats. ( Maina, CI; Ogunde, M, 2005) |
| "To establish whether propranolol can reverse left ventricular hypertrophy in hypertensive rats." | 3.73 | Reversal of left ventricular hypertrophy by propranolol in hypertensive rats. ( Maina, CI; Ogunde, M, 2005) |
| " To assess whether these differential structural effects do translate into different effects on LV function and on heart failure mortality, Bd or sham Bd 8-week-old rats were randomized to vehicle treatment (Vh), chemical sympathectomy ([Sx] 6-hydroxydopamine, 150 mg/kg IP twice a week), beta-adrenoceptor blockade (propranolol [Pro], 40 mg/kg per day PO), or alpha-adrenoceptor blockade (doxazosin [Dox], 5 mg/kg per day PO)." | 3.73 | Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure. ( Busca, G; Cesana, F; Clari, F; Ferrari, AU; Ferrero, I; Gatti, C; Janetti, MB; Mancia, G; Palladini, G; Perlini, S; Tozzi, R; Vezzoli, M, 2006) |
| "The effects of propranolol and atenolol were investigated on arterial hypertension, cardiomyocyte hypertrophy, and ventricular ischaemic lesions induced by an 8-week treatment with the nitric oxide synthase inhibitor N(omega)-nitro-L-arginine methyl ester (L-NAME; 20 mg/rat per day) in Wistar rats." | 3.71 | Attenuation of hypertension, cardiomyocyte hypertrophy, and myocardial fibrosis by beta-adrenoceptor blockers in rats under long-term blockade of nitric oxide synthesis. ( Antunes, E; de Azevedo, AP; De Luca, IM; De Nucci, G; De Oliveira, CF; Pacca, SR, 2002) |
| "In a rat model of chronic pressure overload induced by abdominal aortic banding, we evaluated the effects on left ventricular hypertrophy (LVH) of the propranolol isomers, L-propranolol and D-propranolol, which compared to L-isomer is approximately 50-fold less potent as a beta-adrenoceptor antagonist, but is similarly potent as a membrane-stabilizer, as well as of timolol, a non-selective beta-adrenergic antagonist devoid of membrane stabilizing activity, and disopyramide, which is a membrane stabilizer, but not a beta-adrenoceptor blocker." | 3.71 | Attenuation of aortic banding-induced cardiac hypertrophy by propranolol is independent of beta-adrenoceptor blockade. ( Fadda, A; Ferrari, AU; Marano, G; Palazzesi, S; Vergari, A, 2002) |
| "To investigate the effects of perindopril, propranolol, and dihydrochlorothiazide on artery wall thickening, left ventricular hypertrophy, and cardiac fibrosis in spontaneously hypertensive rats (SHR)." | 3.70 | Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats. ( Chen, DG; Chen, SC; Rui, HB; Su, JZ; Wang, HJ; Wang, XY; Wu, KG, 1999) |
| "Pathological cardiac hypertrophy is associated with the expression of a gene profile reminiscent of foetal development." | 1.34 | Propranolol causes a paradoxical enhancement of cardiomyocyte foetal gene response to hypertrophic stimuli. ( Catalano, L; Fasanaro, P; Marano, G; Musumeci, M; Palazzesi, S; Patrizio, M; Stati, T, 2007) |
| "Volume reduction surgery for dilated cardiomyopathy has not yielded predictable outcomes." | 1.32 | Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery. ( Komeda, M; Koyama, T; Nishimura, K; Soga, Y; Ueyama, K; Unimonh, O, 2003) |
| "Hyperthyroidism was induced by daily intraperitoneal injection of thyroxine (T4) (600 microg/kg) with or without cilazapril (10 mg/kg per day, orally), and control rats were given by vehicle." | 1.31 | Cilazapril prevents cardiac hypertrophy and postischemic myocardial dysfunction in hyperthyroid rats. ( Asahi, T; Oshiro, Y; Shimabukuro, M; Takasu, N; Yoshida, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 13 (50.00) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freitas, F | 1 |
| Estato, V | 1 |
| Lessa, MA | 1 |
| Tibiriçá, E | 1 |
| Matsuura, N | 1 |
| Nagasawa, K | 1 |
| Minagawa, Y | 1 |
| Ito, S | 1 |
| Sano, Y | 1 |
| Yamada, Y | 1 |
| Hattori, T | 1 |
| Watanabe, S | 1 |
| Murohara, T | 1 |
| Nagata, K | 1 |
| Ozçakar, ZB | 1 |
| Yalçinkaya, F | 1 |
| Ensari, A | 1 |
| Kendirli, T | 1 |
| Ekim, M | 1 |
| Fitöz, S | 1 |
| Panama, BK | 1 |
| Latour-Villamil, D | 1 |
| Farman, GP | 1 |
| Zhao, D | 1 |
| Bolz, SS | 1 |
| Kirshenbaum, LA | 1 |
| Backx, PH | 1 |
| Park, YH | 1 |
| Kim, J | 1 |
| Rakić, D | 1 |
| Rumboldt, Z | 1 |
| Bagatin, J | 1 |
| Polić, S | 1 |
| Koyama, T | 1 |
| Nishimura, K | 1 |
| Soga, Y | 1 |
| Unimonh, O | 1 |
| Ueyama, K | 1 |
| Komeda, M | 1 |
| Marano, G | 3 |
| Palazzesi, S | 3 |
| Vergari, A | 2 |
| Catalano, L | 2 |
| Gaudi, S | 1 |
| Testa, C | 1 |
| Canese, R | 1 |
| Carpinelli, G | 1 |
| Podo, F | 1 |
| Ferrari, AU | 3 |
| Maina, CI | 1 |
| Ogunde, M | 1 |
| Perlini, S | 1 |
| Ferrero, I | 1 |
| Palladini, G | 1 |
| Tozzi, R | 1 |
| Gatti, C | 1 |
| Vezzoli, M | 1 |
| Cesana, F | 1 |
| Janetti, MB | 1 |
| Clari, F | 1 |
| Busca, G | 1 |
| Mancia, G | 1 |
| Patrizio, M | 1 |
| Musumeci, M | 1 |
| Stati, T | 1 |
| Fasanaro, P | 1 |
| Wagner, R | 1 |
| von Hundelshausen, B | 1 |
| Tempel, G | 1 |
| Schneck, HJ | 1 |
| Pichlmeier, R | 1 |
| Hipp, R | 1 |
| Kawaguchi, O | 1 |
| Goto, Y | 1 |
| Futaki, S | 1 |
| Ohgoshi, Y | 1 |
| Yaku, H | 1 |
| Suga, H | 1 |
| Kingwell, BA | 1 |
| Krause, L | 1 |
| Julius, S | 1 |
| Haczyński, J | 1 |
| Spring, A | 1 |
| Bélichard, P | 1 |
| Savard, P | 1 |
| Cardinal, R | 1 |
| Nadeau, R | 1 |
| Gosselin, H | 1 |
| Paradis, P | 1 |
| Rouleau, JL | 1 |
| Ostman-Smith, I | 1 |
| Jalil, JE | 1 |
| Ebensperger, R | 1 |
| Meléndez, J | 1 |
| Acevedo, E | 1 |
| Sapag-Hagar, M | 1 |
| González-Jara, F | 1 |
| Gálvez, A | 1 |
| Pérez-Montes, V | 1 |
| Lavandero, S | 1 |
| Pantos, CI | 1 |
| Mourouzis, IS | 1 |
| Tzeis, SM | 1 |
| Malliopoulou, V | 1 |
| Cokkinos, DD | 1 |
| Asimacopoulos, P | 1 |
| Carageorgiou, HC | 1 |
| Varonos, DD | 1 |
| Cokkinos, DV | 1 |
| Su, JZ | 1 |
| Chen, SC | 1 |
| Wu, KG | 1 |
| Chen, DG | 1 |
| Rui, HB | 1 |
| Wang, XY | 1 |
| Wang, HJ | 1 |
| Hart, CY | 1 |
| Meyer, DM | 1 |
| Tazelaar, HD | 1 |
| Grande, JP | 1 |
| Burnett , JC | 1 |
| Housmans, PR | 1 |
| Redfield, MM | 1 |
| Asahi, T | 1 |
| Shimabukuro, M | 1 |
| Oshiro, Y | 1 |
| Yoshida, H | 1 |
| Takasu, N | 1 |
| Pacca, SR | 1 |
| de Azevedo, AP | 1 |
| De Oliveira, CF | 1 |
| De Luca, IM | 1 |
| De Nucci, G | 1 |
| Antunes, E | 1 |
| Fadda, A | 1 |
| Sarukhanian, OV | 1 |
| Torgomian, TG | 1 |
| Sisakian, AS | 1 |
1 trial available for propranolol and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Effects of four antihypertensive monotherapies on cardiac mass and function in hypertensive patients with left ventricular hypertrophy: randomized prospective study.
Topics: Adult; Aged; Antihypertensive Agents; Chlorthalidone; Croatia; Echocardiography; Female; Heart Ventr | 2002 |
25 other studies available for propranolol and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Cardiac microvascular rarefaction in hyperthyroid rats is reversed by losartan, diltiazem, and propranolol.
Topics: Adrenergic beta-Antagonists; Animals; Diltiazem; Hyperthyroidism; Hypertrophy, Left Ventricular; Los | 2015 |
Restraint stress exacerbates cardiac and adipose tissue pathology via β-adrenergic signaling in rats with metabolic syndrome.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Animals; Echocardiography; Glucose Intolerance; Hyperte | 2015 |
Thrombotic microangiopathy in a pediatric patient: question.
Topics: Acute Kidney Injury; Antihypertensive Agents; Biopsy; Child; Diagnosis, Differential; Enalapril; Fol | 2009 |
Nuclear factor kappaB downregulates the transient outward potassium current I(to,f) through control of KChIP2 expression.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hypertrophy, Left Ventricular; Kv | 2011 |
Bidirectional ventricular tachycardia in a patient with acute myocardial infarction and aortic stenosis.
Topics: Aged; Aortic Valve Stenosis; Echocardiography; Electrocardiography; Follow-Up Studies; Humans; Hyper | 2013 |
Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery.
Topics: Acute Disease; Animals; Cardiac Output; Cardiac Volume; Cardiomyopathy, Dilated; Diastole; Dogs; Ech | 2003 |
Inhibition of left ventricular remodelling preserves chamber systolic function in pressure-overloaded mice.
Topics: Animals; Aorta; Echocardiography; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Im | 2003 |
Reversal of left ventricular hypertrophy by propranolol in hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Hypertension; Hypertrophy, Left Ventricular; Male; Propranolol | 2005 |
Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Blood Pressure | 2006 |
Propranolol causes a paradoxical enhancement of cardiomyocyte foetal gene response to hypertrophic stimuli.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Cells, Cultured; Gene Expression Profiling; Gene | 2007 |
[Left heart failure in anesthesia in a child pretreated with propranolol--case report].
Topics: Adolescent; Anesthesia, General; Catheters, Indwelling; Drug Therapy, Combination; Female; Heart Fai | 1994 |
The effects of dynamic cardiac compression on ventricular mechanics and energetics. Role of ventricular size and contractility.
Topics: Animals; Assisted Circulation; Coronary Circulation; Cross Circulation; Dobutamine; Dogs; Hypertroph | 1994 |
The effect of hypertensive episodes and cardiac hypertrophy on the canine cardiac baroreflex.
Topics: Analysis of Variance; Animals; Baroreflex; Blood Pressure; Body Weight; Disease Models, Animal; Dogs | 1994 |
[Effect of treatment with propranolol or pindolol on the left ventricular myocardium mass in patients with slight essential arterial hypertension].
Topics: Adult; Aged; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Pindolo | 1993 |
Markedly different effects on ventricular remodeling result in a decrease in inducibility of ventricular arrhythmias.
Topics: Animals; Captopril; Cardiac Pacing, Artificial; Hypertrophy, Left Ventricular; Male; Myocardial Infa | 1994 |
Reduction by oral propranolol treatment of left ventricular hypertrophy secondary to pressure-overload in the rat.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Aortic Coarctation; Bo | 1995 |
Effects of antihypertensive treatment on cardiac IGF-1 during prevention of ventricular hypertrophy in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hypertrophy, Left Ventricular; I | 1999 |
Propranolol diminishes cardiac hypertrophy but does not abolish acceleration of the ischemic contracture in hyperthyroid hearts.
Topics: Adrenergic beta-Antagonists; Animals; Glycogen; Hyperthyroidism; Hypertrophy, Left Ventricular; Male | 2000 |
Effects of perindopril, propranolol, and dihydrochlorothiazide on cardiovascular remodelling in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Age | 1999 |
Load versus humoral activation in the genesis of early hypertensive heart disease.
Topics: Angiotensin II; Animals; Catecholamines; Diastole; Disease Models, Animal; Dogs; Endothelin-1; Heart | 2001 |
Cilazapril prevents cardiac hypertrophy and postischemic myocardial dysfunction in hyperthyroid rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Cell S | 2001 |
Attenuation of hypertension, cardiomyocyte hypertrophy, and myocardial fibrosis by beta-adrenoceptor blockers in rats under long-term blockade of nitric oxide synthesis.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressu | 2002 |
Attenuation of aortic banding-induced cardiac hypertrophy by propranolol is independent of beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Disopyramide; Hypertrophy, Left Ventricular; | 2002 |
[A comparative study of anapriline and carvedilol effectiveness in patients with thyrotoxicosis in pre- and postoperative periods].
Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Female; Humans; Hyperthyroidism; Hypertr | 2002 |
[Hypertensive heart. Experience in the clinical use of sectral (acebutolol)].
Topics: Acebutolol; Adrenergic beta-Antagonists; Blood Pressure; Humans; Hypertension; Hypertrophy, Left Ven | 1992 |