Page last updated: 2024-11-03

propranolol and Lassitude

propranolol has been researched along with Lassitude in 35 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia."9.05Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984)
"A double-blind crossover trial was undertaken to compare the efficacy of sustained-release clonidine and long-acting propranolol in the treatment of 20 patients (8 males and 12 females) with sustained hypertension."9.05Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension. ( Lawson, AA; Rodrigues, E, 1982)
"Hemodynamic response to exercise before and 10 minutes after propranolol (5 mg intravenously) was studied in 10 young patients with pure mitral stenosis who had normal sinus rhythm and no cardiac failure."7.66Hemodynamic response to exercise after propranolol in patients with mitral stenosis. ( Betocchi, S; Bonzani, G; Condorelli, M; Giudice, P; Giuffrida, G; Mazza, F; Miceli, D; Piscione, F, 1979)
"Xamoterol was no different from placebo in these respects."6.67Comparison of the effects of xamoterol, atenolol and propranolol on breathlessness, fatigue and plasma electrolytes during exercise in healthy volunteers. ( Faergeman, O; Jensen, HK; Sørensen, EV, 1991)
" Two other tests were undertaken to assess the sensitivity of each scale to a change in symptom perception: a double-blind treatment with propranolol, 80 mg, (ie, active therapy; to increase the sensation of breathlessness and general fatigue during exercise) or matching placebo."5.09A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise. ( Aitchison, T; Christie, J; Dargie, H; Grant, S; Henderson, E; McMurray, J; Zare, S, 1999)
"After 4 days of drug treatment with comparable doses of propranolol (40 and 80 mg), metoprolol (50 and 100 mg), or placebo, mood (POMS) and anxiety states (STAI) were assessed in healthy volunteers, before and after 1 h of treadmill walking exercise at 50% maximum oxygen uptake."5.08Acute effects of beta blockade and exercise on mood and anxiety. ( Eagles, C; Ferner, R; Head, A; Kendall, MJ, 1996)
"The effects of captopril, methyldopa, and propranolol were assessed for sense of well-being and vitality among 626 men with mild to moderate hypertension in a multicenter, randomized, double-blind clinical trial."5.06Effects of antihypertensive medications on vitality and well-being. ( Croog, SH; Levine, S; Sudilovsky, A; Testa, MA, 1987)
"The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia."5.05Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984)
"A double-blind crossover trial was undertaken to compare the efficacy of sustained-release clonidine and long-acting propranolol in the treatment of 20 patients (8 males and 12 females) with sustained hypertension."5.05Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension. ( Lawson, AA; Rodrigues, E, 1982)
"Hemodynamic response to exercise before and 10 minutes after propranolol (5 mg intravenously) was studied in 10 young patients with pure mitral stenosis who had normal sinus rhythm and no cardiac failure."3.66Hemodynamic response to exercise after propranolol in patients with mitral stenosis. ( Betocchi, S; Bonzani, G; Condorelli, M; Giudice, P; Giuffrida, G; Mazza, F; Miceli, D; Piscione, F, 1979)
"Propranolol was somewhat better than flunarizine in reducing the severity of migraine attacks, although this may have been due to a selection bias."2.68Post-marketing cohort study comparing the safety and efficacy of flunarizine and propranolol in the prophylaxis of migraine. ( Amery, WK; De Locht, P; Verspeelt, J, 1996)
"Xamoterol was no different from placebo in these respects."2.67Comparison of the effects of xamoterol, atenolol and propranolol on breathlessness, fatigue and plasma electrolytes during exercise in healthy volunteers. ( Faergeman, O; Jensen, HK; Sørensen, EV, 1991)
"Monitoring for adverse effects in an integral part of controlled clinical trials."2.66Survival analysis of adverse effects data in the Beta-Blocker Heart Attack Trial. ( Davis, BR; Furberg, CD; Williams, CB, 1987)
"However, severe mitral regurgitation (MR) is a relatively uncommon manifestation of Graves' disease."1.62Reversible, severe mitral regurgitation in thyrotoxic Graves' disease. ( Fekri, K; Michel, CM; Tamilia, M, 2021)
"Reactive hypoglycemia was documented in ten postgastrectomy patients by a control oral glucose tolerance test (OGTT)."1.25Effect of adrenergic agents on postgastrectomy hypoglycemia. ( Leichter, SB; Permutt, MA, 1975)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199024 (68.57)18.7374
1990's7 (20.00)18.2507
2000's1 (2.86)29.6817
2010's1 (2.86)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Park, BD1
Lyn-Kew, K1
Granchelli, A1
Mehta, A1
Fekri, K1
Michel, CM1
Tamilia, M1
Akcam, M1
Pirgon, O1
Salman, H1
Kockar, C1
Fellenius, E1
Shand, DG1
Noyes, R1
Anderson, DJ1
Clancy, J1
Crowe, RR1
Slymen, DJ1
Ghoneim, MM1
Hinrichs, JV1
Rodrigues, E1
Lawson, AA1
Karlsson, J1
Sjödin, B1
Jacobs, I1
Kaiser, P1
Derman, WE1
Dunbar, F1
Haus, M1
Lambert, M1
Noakes, TD1
Verspeelt, J1
De Locht, P1
Amery, WK1
Head, A1
Kendall, MJ1
Ferner, R1
Eagles, C1
Kohut, ML1
Davis, JM1
Jackson, DA1
Colbert, LH1
Strasner, A1
Essig, DA1
Pate, RR1
Ghaffar, A1
Mayer, EP1
Grant, S1
Aitchison, T1
Henderson, E1
Christie, J1
Zare, S1
McMurray, J1
Dargie, H1
Chelimsky, G1
Chelimsky, T1
Anderson, SD1
Bye, PT1
Perry, CP1
Hamor, GP1
Theobald, G1
Nyberg, G2
Simpson, WT1
Giuffrida, G1
Bonzani, G1
Betocchi, S1
Piscione, F1
Giudice, P1
Miceli, D1
Mazza, F1
Condorelli, M1
Vedin, A1
Wilhelmsson, C1
Aksnes, EG1
Leichter, SB1
Permutt, MA1
Gullestad, L1
Birkeland, K1
Nordby, G1
Larsen, S1
Kjekshus, J1
Sørensen, EV1
Jensen, HK1
Faergeman, O1
Areskog, NH1
Koella, WP1
Lewis, RV1
Jackson, PR1
Ramsay, LE1
Broberg, S1
Katz, A1
Sahlin, K1
Levine, S1
Croog, SH1
Sudilovsky, A1
Testa, MA1
Davis, BR1
Furberg, CD1
Williams, CB1
Rosen, RC1
Kostis, JB1
Flamenbaum, W1
Weber, MA1
McMahon, FG1
Materson, BJ1
Carr, AA1
Poland, M1
Dean, GA1
Lohmöller, G1
Lydtin, H1
Hansson, L1
Olander, R1
Aberg, H1
Malmcrona, R1
Westerlund, A1
McLean, CE1
Deane, BC1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Indirect Decompression Sufficient for the Treatment of Central Stenosis?: A Randomized Controlled Trial[NCT04708977]0 participants (Actual)Interventional2021-02-08Withdrawn (stopped due to The patient population is too low to conduct the study in a feasible and meaningful amount of time.)
The Role of the Nose for Physical Capacity[NCT04712799]Phase 467 participants (Anticipated)Interventional2021-01-13Recruiting
Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart Failure Reduced Ejection Fraction and Acute Decompensation With Low Cardiac Output: A Single Center, Randomized, Non-Blinded, and Parallel Study (PRIORITY-ADHF Study)[NCT02767024]Phase 40 participants (Actual)Interventional2018-05-01Withdrawn (stopped due to No patients enrolled)
[NCT00000492]Phase 30 participants Interventional1977-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for propranolol and Lassitude

ArticleYear
Muscle fatigue and beta-blockers--a review.
    International journal of sports medicine, 1983, Volume: 4, Issue:1

    Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Atenolol; Dogs; Dose-Response Relat

1983
CNS-related (side-)effects of beta-blockers with special reference to mechanisms of action.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adrenergic beta-Antagonists; Amphetamine; Animals; Anxiety; Blood-Brain Barrier; Central Nervous Sys

1985
Biobehavioral sequellae associated with adrenergic-inhibiting antihypertensive agents: a critical review.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 1985, Volume: 4, Issue:6

    Topics: Animals; Antihypertensive Agents; Cats; Cognition; Depression; Electroencephalography; Fatigue; Feed

1985

Trials

12 trials available for propranolol and Lassitude

ArticleYear
Diazepam and propranolol in panic disorder and agoraphobia.
    Archives of general psychiatry, 1984, Volume: 41, Issue:3

    Topics: Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Double-Blind

1984
Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension.
    Current medical research and opinion, 1982, Volume: 8, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Double-Blind Method;

1982
Post-marketing cohort study comparing the safety and efficacy of flunarizine and propranolol in the prophylaxis of migraine.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Basal Ganglia Diseases; Belgium; Child; Cohort Studies;

1996
Acute effects of beta blockade and exercise on mood and anxiety.
    British journal of sports medicine, 1996, Volume: 30, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Affect; Age Factors; Anxiety; Body Weight; Confusion; Depression

1996
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
A comparison of the reproducibility and the sensitivity to change of visual analogue scales, Borg scales, and Likert scales in normal subjects during submaximal exercise.
    Chest, 1999, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Dyspnea; Exercise; Exercise Test; Fatigue;

1999
Nature and incidence of unwanted effects with atenolol.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 3

    Topics: Atenolol; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Extremities; Fatigue; Hum

1977
Effects of labetalol and propranolol on blood pressure at rest and during isometric and dynamic exercise.
    European journal of clinical pharmacology, 1979, Volume: 16, Issue:5

    Topics: Adult; Blood Pressure; Ethanolamines; Fatigue; Heart Rate; Humans; Isometric Contraction; Labetalol;

1979
Effects of selective beta 2-adrenoceptor blockade on serum potassium and exercise performance in normal men.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Glucose; Blood Pressur

1991
Comparison of the effects of xamoterol, atenolol and propranolol on breathlessness, fatigue and plasma electrolytes during exercise in healthy volunteers.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Atenolol; Blood Pressure; Calcium; Exercise Test; Fatigue; Heart Ra

1991
Effects of antihypertensive medications on vitality and well-being.
    The Journal of family practice, 1987, Volume: 25, Issue:4

    Topics: Adaptation, Psychological; Antihypertensive Agents; Attitude to Health; Captopril; Clinical Trials a

1987
Survival analysis of adverse effects data in the Beta-Blocker Heart Attack Trial.
    Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6

    Topics: Adult; Aged; Bronchial Spasm; Clinical Trials as Topic; Cross-Sectional Studies; Depression; Double-

1987
Monotherapy with labetalol compared with propranolol. Differential effects by race.
    Journal of clinical hypertension, 1985, Volume: 1, Issue:1

    Topics: Adult; Aged; Black or African American; Bradycardia; Clinical Trials as Topic; Dizziness; Double-Bli

1985

Other Studies

20 other studies available for propranolol and Lassitude

ArticleYear
A 62-Year-Old Woman With Diffuse Myalgias, Fatigue, and Shortness of Breath.
    Chest, 2020, Volume: 157, Issue:3

    Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Anticoagulants; Antithyroid Agents; Atrial Fibrill

2020
Reversible, severe mitral regurgitation in thyrotoxic Graves' disease.
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Echocardiography; Fatigue; Female; Graves Di

2021
Multiple gastrointestinal hemangiomatosis successfully treated with propranolol.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 60, Issue:3

    Topics: Adolescent; Anemia; Colonic Neoplasms; Endoscopy, Gastrointestinal; Fatigue; Hemangioma, Cavernous;

2015
Clinical pharmacology of the beta-blocking drugs: implications for the postinfarction patient.
    Circulation, 1983, Volume: 67, Issue:6 Pt 2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Bronchial Spasm; Fatigue; Heart Failure; Humans

1983
Relevance of muscle fibre type to fatigue in short intense and prolonged exercise in man.
    Ciba Foundation symposium, 1981, Volume: 82

    Topics: Biopsy; Fatigue; Female; Glycogen; Humans; Lactates; Lactic Acid; Male; Muscles; Physical Endurance;

1981
Chronic beta-blockade does not influence muscle power output during high-intensity exercise of short-duration.
    European journal of applied physiology and occupational physiology, 1993, Volume: 67, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Benzopyrans; Blood Pressure; Cardiovascular Physiologi

1993
The role of stress hormones in exercise-induced suppression of alveolar macrophage antiviral function.
    Journal of neuroimmunology, 1998, Volume: 81, Issue:1-2

    Topics: Adrenal Insufficiency; Adrenalectomy; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals

1998
Familial association of autonomic and gastrointestinal symptoms.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2001, Volume: 11, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Autonomic Nervous System Diseases; Child; Fatigue; Fem

2001
Limitation of work performance in normal adult males in the presence of beta-adrenergic blockade.
    Australian and New Zealand journal of medicine, 1979, Volume: 9, Issue:5

    Topics: Adult; Blood Pressure; Fatigue; Fatty Acids, Nonesterified; Heart Rate; Hemodynamics; Humans; Lactat

1979
Hemodynamic response to exercise after propranolol in patients with mitral stenosis.
    The American journal of cardiology, 1979, Volume: 44, Issue:6

    Topics: Adult; Blood Pressure; Cardiac Output; Dyspnea; Fatigue; Female; Heart Rate; Hemodynamics; Humans; I

1979
[Beta-blockers--dangerous for skiers?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1977, Apr-30, Volume: 97, Issue:12

    Topics: Adult; Fatigue; Female; Humans; Propranolol; Skiing

1977
Effect of adrenergic agents on postgastrectomy hypoglycemia.
    Diabetes, 1975, Volume: 24, Issue:11

    Topics: Adult; Aged; Blood Glucose; Fatigue; Female; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia;

1975
Effects and adverse effects of autonomic blockade in physical exercise.
    The American journal of cardiology, 1985, Apr-26, Volume: 55, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Fatigue; Heart Rate; Humans; Metopro

1985
Side-effects of beta-blockers assessed using visual analogue scales.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Acebutolol; Adrenergic beta-Antagonists; Analysis of Variance; Atenolol; Dreams; Fatigue; Humans; Hy

1985
Propranolol enhances adenine nucleotide degradation in human muscle during exercise.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:6

    Topics: Adenine Nucleotides; Adult; Ammonia; Fatigue; Glycolysis; Humans; Lactates; Lactic Acid; Male; Muscl

1988
Mitral valve prolapse.
    Hospital practice (Office ed.), 1985, Sep-15, Volume: 20, Issue:9

    Topics: Adult; Arrhythmias, Cardiac; Dyspnea; Fatigue; Female; Heart Function Tests; Humans; Male; Mental Di

1985
Unstable angina.
    Southern medical journal, 1973, Volume: 66, Issue:7

    Topics: Angina Pectoris; Anticoagulants; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Ele

1973
[Hyperkinetic heart syndrome].
    Fortschritte der Medizin, 1971, Aug-19, Volume: 89, Issue:22

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Cardiac Output; Combat Disorders; Diagnosis, Differenti

1971
Treatment of hypertension with propranolol and hydralazine.
    Acta medica Scandinavica, 1971, Volume: 190, Issue:6

    Topics: Adult; Creatinine; Drug Interactions; Fatigue; Female; Humans; Hydralazine; Hypertension; Male; Midd

1971
Propranolol dose determinants including blood level studies.
    Angiology, 1970, Volume: 21, Issue:8

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Fatigue; Heart Rate; Humans; Propranolol; Tablet

1970