Page last updated: 2024-11-03

propranolol and Kidney Diseases

propranolol has been researched along with Kidney Diseases in 41 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" In a double-blind cross-over study the antihypertensive action and side-effects of labetalol and propranolol were compared in 18 previously untreated outpatients with hypertension, WHO stage I--III."9.05Labetalol in the treatment of hypertension in patients with normal and impaired renal function. ( Berg, KJ; Nilsen, OG; Walstad, RA; Wessel-Aas, T, 1982)
"1 Pindolol and propranolol were administered orally in equipotent antihypertensive doses to 14 subjects with mild to moderate hypertension in an open cross-over study."9.05Effect of pindolol and propranolol on renal function of patients with hypertension. ( Pasternack, A; Pörsti, P; Pöyhönen, L, 1982)
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics."7.67Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984)
" In a double-blind cross-over study the antihypertensive action and side-effects of labetalol and propranolol were compared in 18 previously untreated outpatients with hypertension, WHO stage I--III."5.05Labetalol in the treatment of hypertension in patients with normal and impaired renal function. ( Berg, KJ; Nilsen, OG; Walstad, RA; Wessel-Aas, T, 1982)
"1 Pindolol and propranolol were administered orally in equipotent antihypertensive doses to 14 subjects with mild to moderate hypertension in an open cross-over study."5.05Effect of pindolol and propranolol on renal function of patients with hypertension. ( Pasternack, A; Pörsti, P; Pöyhönen, L, 1982)
"Minoxidil was used to treat 26 patients (17 to 67 years old) with severe hypertension and varying degrees of renal function."5.04Long-term clinical effects, bioavailability, and kinetics of minoxidil in relation to renal function. ( Affrime, M; Busby, P; Kim, KE; Lowenthal, DT; Martinez, EW; Mutterperl, R; Onesti, G; Shirk, J; Swartz, C, 1978)
" However, nipradilol, at doses of 10 and 15 mg/kg/day, significantly decreased proteinuria and glomerulosclerosis, while propranolol did not."3.72A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol. ( Hasuike, Y; Hiraoka, K; Inoue, T; Itahana, R; Izumi, M; Miyagawa, K; Nakanishi, T; Nishihara, F; Takamitsu, Y, 2003)
" Serum angiotensin converting enzyme activity (ACEA) and plasma renin activity (PRA) were determined in rats under different experimental conditions such as: nephrotic syndrome (NS), bilateral nephrectomy (BN), renovascular hypertension (RH), dehydration (DEH), anaesthesia (AN), low sodium diet (LSD) and high sodium diet (HSD), and injection with propranolol (PRO) and isoprenaline (ISO)."3.68Serum angiotensin converting enzyme activity and plasma renin activity in experimental models of rats. ( Cruz, C; Ibarra-Rubio, ME; Pedraza-Chaverrí, J; Peña, JC; Tapia, E, 1990)
"Studies were carried out in 15 patients with renal insufficiency and hypertension to compare the long-term effects of methyldopa and propranolol on renal hemodynamics."3.67Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency. ( Alterman, L; Bank, DE; Bank, N; Lowenstein, I; Zelen, R, 1984)
"The mechanisms responsible for the increased bioavailability of propranolol in renal dysfunction were investigated in rats."1.32The increased intestinal absorption rate is responsible for the reduced hepatic first-pass extraction of propranolol in rats with cisplatin-induced renal dysfunction. ( Aiba, T; Hashimoto, Y; Mizukami, A; Okabe, H; Taguchi, M; Yasuhara, M, 2003)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199035 (85.37)18.7374
1990's2 (4.88)18.2507
2000's3 (7.32)29.6817
2010's1 (2.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Takamitsu, Y1
Nakanishi, T1
Nishihara, F1
Hasuike, Y1
Izumi, M1
Inoue, T1
Hiraoka, K1
Itahana, R1
Miyagawa, K1
Okabe, H1
Mizukami, A1
Taguchi, M1
Aiba, T1
Yasuhara, M1
Hashimoto, Y1
TSOLAKAS, TC1
DAVIES, JP1
ORAM, S1
Varela, JA1
Epstein, M1
Oster, JR1
Balant, LP1
Dayer, P1
Fabre, J1
Coevoet, B1
Lambrey, G1
de Frémont, JF1
Hardin, JM1
Desplan, C1
Calmette, C1
Makdassi, R1
Andrejak, M1
Moukhtar, MS1
Fournier, A1
Lowenstein, I1
Alterman, L1
Zelen, R1
Bank, DE1
Bank, N1
Walstad, RA1
Berg, KJ1
Wessel-Aas, T1
Nilsen, OG1
Wilkinson, R1
Sellars, L1
Pickering, M1
Robson, V1
Kerr, DN1
Pasternack, A1
Pörsti, P1
Pöyhönen, L1
al-Damluji, S1
Meek, JH1
Markenson, JA1
Sherman, RL1
Naess, K1
Bühler, FR2
Burkart, F1
Lütold, BE1
Küng, M1
Marbet, G1
Pfisterer, M1
Lowenthal, DT1
Onesti, G1
Mutterperl, R1
Affrime, M1
Martinez, EW1
Kim, KE1
Busby, P1
Shirk, J1
Swartz, C1
McGrath, BP1
Tiller, DJ1
Bune, A1
Chalmers, JP1
Korner, PI1
Uther, JB1
Cecchettin, M1
Albertini, A1
Mioni, G1
Castellani, A1
Cristinelli, L1
Maiorca, R1
Heynen, G1
Franchimont, P1
Börner, H1
Falkenhagen, D1
Rohmann, H1
Krüger, M1
Russell, SB1
Woods, JR1
Brinkman, CR1
Birkenhäger, WH1
Wester, A1
Ibarra-Rubio, ME1
Cruz, C1
Tapia, E1
Peña, JC1
Pedraza-Chaverrí, J1
Isozaki, S1
Wells, TG1
Ulstrom, RA1
Nevins, TE1
Wood, M1
Norès, JM1
Lignières, G1
Tcherdakoff, P1
Moreira, J1
Barata, JD1
Olias, J1
Kincaid-Smith, P1
Hua, AS1
Doherty, JE1
Kane, JJ1
Modlinger, RS1
Nicolis, GL1
Krakoff, LR1
Gabrilove, JL1
Frohlich, ED1
Tarazi, RC2
Dustan, HP1
Aroesty, JM1
Cohen, SI1
Morkin, E1
Pohl, JE1
Thurston, H1
Swales, JD1
Kessler, KM1
Levy, RH1
Smith, GH1
Laragh, JH1
Vaughan, ED1
Brunner, HR1
Gavras, H1
Baer, L1
Schwartz, GJ1
Cornfeld, D1
Lehr, D1
Krukowski, M1
Colón, R1

Reviews

5 reviews available for propranolol and Kidney Diseases

ArticleYear
Beta-blockers and the kidney.
    Mineral and electrolyte metabolism, 1982, Volume: 8, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Cardiac Output; Glomerular Filtration

1982
Consequences of renal insufficiency on the hepatic clearance of some drugs.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:6

    Topics: Adrenergic beta-Antagonists; Biotransformation; Dextropropoxyphene; Ethanolamines; Humans; Kidney Di

1983
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986
Clinical pharmacology and therapeutics use of digitalis glycosides.
    Drugs, 1973, Volume: 6, Issue:3

    Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Digitalis Glycosides; Digitoxin; Digoxin; Heart; He

1973
Individualization of dosage of antiarrhythmic drugs.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Heart Diseases; Humans; Ki

1974

Trials

4 trials available for propranolol and Kidney Diseases

ArticleYear
Labetalol in the treatment of hypertension in patients with normal and impaired renal function.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 665

    Topics: Adult; Aged; Double-Blind Method; Ethanolamines; Female; Half-Life; Humans; Hypertension; Kidney Dis

1982
Effect of pindolol and propranolol on renal function of patients with hypertension.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Adult; Female; Humans; Hypertension; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Pind

1982
Long-term clinical effects, bioavailability, and kinetics of minoxidil in relation to renal function.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Aged; Biological Availability; Blood Pressure; Clinical Trials as Topic; Female;

1978
Beta-adrenergic blocking therapy in hypertension: selection of patients.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Blood Volume; Body Surface Area; Cardiac Output;

1970

Other Studies

32 other studies available for propranolol and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol.
    Nephron. Physiology, 2003, Volume: 93, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cyclic GMP; Enzyme Inhibitors; Hypertension; Kidney; Kidney Di

2003
The increased intestinal absorption rate is responsible for the reduced hepatic first-pass extraction of propranolol in rats with cisplatin-induced renal dysfunction.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Biological Availability; Cisplatin; Dose-Response Relationship

2003
PROPRANOLOL IN ATTEMPTED MAINTENANCE OF SINUS RHYTHM AFTER ELECTRICAL DEFIBRILLATION.
    Lancet (London, England), 1964, Nov-14, Volume: 2, Issue:7368

    Topics: Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Electric Countershock; Hepatitis; Human

1964
[Rapid preoperative preparation with iopanoic acid in severe liver toxicity due to methimazole: anesthetic implications].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, Intravenous; Antithyroid Agents; Chemical and Drug I

2008
[Evidence, in uremic man, of the role of beta 2 adrenergic receptors in the secretion of parathyroid hormone and calcitonin (author's transl)].
    Nephrologie, 1980, Volume: 1, Issue:1

    Topics: Adult; Calcitonin; Female; Heart Rate; Humans; Kidney Diseases; Male; Metoprolol; Parathyroid Hormon

1980
Comparison of long-term renal hemodynamic effects of methyldopa and propranolol in patients with hypertension and renal insufficiency.
    Journal of clinical pharmacology, 1984, Volume: 24, Issue:10

    Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Furosemide; Humans; Hypertension; Kidney Diseases;

1984
The relative roles of sodium and renin in the hypertension of renal disease. An assessment based on the response to frusemide and propranolol.
    Clinical nephrology, 1981, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Creatinine; Female; Furosemide; Humans; Hypertension, Renal; Kidney Disease

1981
Interference of a propranolol metabolite with serum bilirubin estimation in chronic renal failure.
    British medical journal, 1980, Jun-14, Volume: 280, Issue:6229

    Topics: Bilirubin; Chronic Disease; Humans; Kidney Diseases; Propranolol

1980
Renal involvement in progressive systemic sclerosis: prolonged survival with aggressive antihypertensive management.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Antihypertensive Agents; Cardiomegaly; Digoxin; Drug Therapy, Combination; Female; Furosemide

1979
[Adrenergic beta receptor blockaders].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Feb-28, Volume: 95, Issue:6

    Topics: Adrenergic beta-Antagonists; Anesthesia; Asthma; Bronchial Spasm; Conjunctivitis; Hypoglycemia; Hypo

1975
Antihypertensive beta blocking action as related to renin and age: a pharmacologic tool to identify pathogenetic mechanisms in essential hypertension.
    The American journal of cardiology, 1975, Oct-31, Volume: 36, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Blood Pressure; Female; Hemodynamics; Humans; Hyper

1975
Autonomic blockade and the Valsalva maneuver in patients on maintenance hemodialysis: a hemodynamic study.
    Kidney international, 1977, Volume: 12, Issue:4

    Topics: Adult; Aldosterone; Atropine; Blood Pressure; Blood Volume; Cardiac Output; Chronic Disease; Female;

1977
[Hypersecretion of calcitonin in hypocalcemic syndromes and in stimulation of the autonomic nervous system].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1977, Volume: 13, Issue:1

    Topics: Autonomic Nervous System; Calcitonin; Calcium; Ethanol; Gastrins; Humans; Hypocalcemia; Insulin; Ins

1977
[Behavior of plasms renin activity, hemodynamic parameters and clearance values as influenced by orciprenaline and propranolol in patients with limited kidney function].
    Zeitschrift fur Urologie und Nephrologie, 1976, Volume: 69, Issue:12

    Topics: Adult; Angina Pectoris; Chronic Disease; Female; Glomerulonephritis; Hemodynamics; Humans; Kidney Di

1976
The mechanism of action of mercuric chloride on the isolated perfused rat kidney.
    European journal of clinical investigation, 1975, Jul-29, Volume: 5, Issue:4

    Topics: Angiotensin II; Animals; Bradykinin; Chlorides; Kidney Diseases; Male; Mannitol; Mercury; Mercury Po

1975
The treatment of gestational hypertension.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Diazoxide; Female; Humans; Hydralazine; Hypertension; Hype

1975
[A question of logic].
    Nederlands tijdschrift voor geneeskunde, 1976, Jun-12, Volume: 120, Issue:24

    Topics: Diazoxide; Furosemide; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Male; Middle Aged;

1976
Serum angiotensin converting enzyme activity and plasma renin activity in experimental models of rats.
    Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:6

    Topics: Animals; Disease Models, Animal; Hypertension, Renovascular; Isoproterenol; Kidney Diseases; Male; N

1990
[Therapeutic drug monitoring of propranolol hydrochloride].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48 Suppl

    Topics: Administration, Oral; Aged; Aged, 80 and over; Biological Availability; Chromatography, Gas; Chromat

1990
Hypoglycemia in pediatric renal allograft recipients.
    The Journal of pediatrics, 1988, Volume: 113, Issue:6

    Topics: Child; Child, Preschool; Diuretics; Female; Follow-Up Studies; Graft Rejection; Humans; Hypoglycemia

1988
[Hypertension in pregnant women and beta-blockers. Follow-up of 31 pregnancies].
    Revue francaise de gynecologie et d'obstetrique, 1988, Volume: 83, Issue:10

    Topics: Adult; Blood Pressure; Embryonic and Fetal Development; Female; Follow-Up Studies; Humans; Hypertens

1988
Antihypertensive action of calcium blockade in hypertensive patients with chronic renal disease.
    Nephron, 1985, Volume: 41, Issue:4

    Topics: Adult; Aged; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Female; Humans; Hypertensio

1985
Letter: Beta-adrenergic blocking agents in renal failure.
    British medical journal, 1974, Aug-24, Volume: 3, Issue:5929

    Topics: Adrenergic beta-Antagonists; Creatinine; Glomerulonephritis; Humans; Hypertension; Kidney Diseases;

1974
Some observations on the pathogenesis of Bartter's syndrome.
    The New England journal of medicine, 1973, Nov-08, Volume: 289, Issue:19

    Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Blood Volume; Drug Therapy, Combination; Humans; Hype

1973
Modern concepts in diuretic therapy.
    Postgraduate medicine, 1974, Volume: 56, Issue:5

    Topics: Blood Volume; Creatinine; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hyperten

1974
Bradycardia-tachycardia syndrome: results in twenty-eight patients treated by combined pharmacologic therapy and pacemaker implantation.
    Chest, 1974, Volume: 66, Issue:3

    Topics: Aged; Atropa belladonna; Atropine; Autopsy; Bradycardia; Digitalis Glycosides; Ephedrine; Female; He

1974
Hypertension with renal impairment: influence of intensive therapy.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:172

    Topics: Adolescent; Adult; Chronic Disease; Creatinine; Diazoxide; Female; Glomerulonephritis; Humans; Hyper

1974
Dosage regimens of antiarrhythmics. II. Applications.
    American journal of hospital pharmacy, 1973, Volume: 30, Issue:6

    Topics: Anti-Arrhythmia Agents; Heart Failure; Humans; Injections, Intravenous; Kidney Diseases; Lidocaine;

1973
Antihypertensive action of propranolol. Specific antirenin responses in high and normal renin forms of essential, renal, renovascular and malignant hypertension.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Child; Female; Humans; Hypertensi

1973
Letter: Propranolol in Bartter's syndrome.
    The New England journal of medicine, 1974, Apr-25, Volume: 290, Issue:17

    Topics: Child; Diet; Humans; Hyperaldosteronism; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Ma

1974
Correlation of myocardial and renal necrosis with tissue electrolyte changes.
    JAMA, 1966, Jul-11, Volume: 197, Issue:2

    Topics: Animals; Calcium, Dietary; Catecholamines; Electrolytes; Kidney Diseases; Magnesium; Male; Metaramin

1966