propranolol has been researched along with Invasiveness, Neoplasm in 6 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study demonstrated the antiangiogenic properties of propranolol in vitro and that the drug was able to induce the regression of hemangioma cells via the inhibition of cell cycle progression, invasion, and tube formation, concomitantly with decreased NO and VEGF levels through the down-regulation of the PI3K/Akt/eNOS/VEGF pathway." | 7.81 | Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway. ( Gao, Y; Guo, ZT; Huang, Q; Li, P; Pan, WK, 2015) |
| " One week after starting propranolol treatment, all rats were submitted to chemical induction of oral carcinogenesis with 4-nitroquinoline-1-oxide (4NQO)." | 3.96 | Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion. ( Bernabé, DG; Biasoli, ÉR; Cecilio, HP; Furuse, C; Kayahara, GM; Miyahara, GI; Oliveira, SHP; Pereira, KM; Valente, VB, 2020) |
| "The current study demonstrated the antiangiogenic properties of propranolol in vitro and that the drug was able to induce the regression of hemangioma cells via the inhibition of cell cycle progression, invasion, and tube formation, concomitantly with decreased NO and VEGF levels through the down-regulation of the PI3K/Akt/eNOS/VEGF pathway." | 3.81 | Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway. ( Gao, Y; Guo, ZT; Huang, Q; Li, P; Pan, WK, 2015) |
| "However, β -adrenergic action in breast cancer is controversial." | 1.46 | The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line. ( Bruzzone, A; Entschladen, F; Gargiulo, L; Lüthy, IA; Piñero, CP; Rivero, EM; Zänker, K, 2017) |
| "The human pancreatic cancer cell lines, Miapaca-2 and Bxpc-3, were selected for this study, and in both cell lines, beta1-AR and beta2-AR expression was determined by RT-PCR and Western blotting." | 1.35 | Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol. ( Guo, K; Hu, H; Li, J; Ma, Q; Wang, L; Zhang, D; Zhang, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bravo-Calderón, DM | 1 |
| Assao, A | 1 |
| Garcia, NG | 1 |
| Coutinho-Camillo, CM | 1 |
| Roffé, M | 1 |
| Germano, JN | 1 |
| Oliveira, DT | 1 |
| Cecilio, HP | 1 |
| Valente, VB | 1 |
| Pereira, KM | 1 |
| Kayahara, GM | 1 |
| Furuse, C | 1 |
| Biasoli, ÉR | 1 |
| Miyahara, GI | 1 |
| Oliveira, SHP | 1 |
| Bernabé, DG | 1 |
| Rivero, EM | 1 |
| Piñero, CP | 1 |
| Gargiulo, L | 1 |
| Entschladen, F | 1 |
| Zänker, K | 1 |
| Bruzzone, A | 1 |
| Lüthy, IA | 1 |
| Lee, A | 1 |
| Fraser, SP | 1 |
| Djamgoz, MBA | 1 |
| Pan, WK | 1 |
| Li, P | 1 |
| Guo, ZT | 1 |
| Huang, Q | 1 |
| Gao, Y | 1 |
| Guo, K | 1 |
| Ma, Q | 1 |
| Wang, L | 1 |
| Hu, H | 1 |
| Li, J | 1 |
| Zhang, D | 1 |
| Zhang, M | 1 |
6 other studies available for propranolol and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Beta adrenergic receptor activation inhibits oral cancer migration and invasiveness.
Topics: Adrenergic beta-Antagonists; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Mouth Neoplasms; Ne | 2020 |
Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion.
Topics: 4-Nitroquinoline-1-oxide; Adrenergic beta-Antagonists; Animals; Carcinogenesis; Carcinogens; Cytokin | 2020 |
The β 2-Adrenergic Agonist Salbutamol Inhibits Migration, Invasion and Metastasis of the Human Breast Cancer MDA-MB- 231 Cell Line.
Topics: Adrenergic Agonists; Albuterol; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Pro | 2017 |
Propranolol inhibits neonatal Nav1.5 activity and invasiveness of MDA-MB-231 breast cancer cells: Effects of combination with ranolazine.
Topics: Cell Movement; Cell Proliferation; Collagen; Drug Combinations; Female; Gene Expression Regulation, | 2019 |
Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway.
Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Cell Cycle Checkpoints; Cell Proliferation; Ce | 2015 |
Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol.
Topics: Adrenergic beta-Antagonists; Blotting, Western; Cell Line, Tumor; Cell Movement; Enzyme-Linked Immun | 2009 |