propranolol has been researched along with Intermittent Claudication in 19 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with chronic intermittent claudication were included in a double-blind, randomized cross-over study of placebo, propranolol 80 mg b." | 9.05 | Lack of influence of propranolol and metoprolol on walking distance in patients with chronic intermittent claudication. ( Bogaert, MG; Clement, DL, 1983) |
| "Seven patients (5 with arteriosclerosis obliterans and 2 with Buerger's disease) completed a two-phase double-blind crossover trial of propranolol in intermittent claudication." | 9.04 | Controlled trial of propranolol in intermittent claudication. ( Adar, R; Gafni, J; Reichert, N; Shibolet, S, 1975) |
| " Heart rate was lowest during propranolol dosing and blood pressure was lowest during labetalol dosing irrespective of the labetalol dose used." | 6.66 | Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication. ( Lepäntalo, M, 1985) |
| "Ten patients with chronic intermittent claudication were included in a double-blind, randomized cross-over study of placebo, propranolol 80 mg b." | 5.05 | Lack of influence of propranolol and metoprolol on walking distance in patients with chronic intermittent claudication. ( Bogaert, MG; Clement, DL, 1983) |
| "Seven patients (5 with arteriosclerosis obliterans and 2 with Buerger's disease) completed a two-phase double-blind crossover trial of propranolol in intermittent claudication." | 5.04 | Controlled trial of propranolol in intermittent claudication. ( Adar, R; Gafni, J; Reichert, N; Shibolet, S, 1975) |
| "For this update, the Cochrane Peripheral Vascular Diseases Group Trials Search Co-ordinator searched the Specialised Register (last searched March 2013) and the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, 2013, Issue 2)." | 2.49 | Beta blockers for peripheral arterial disease. ( Da Silva, A; Mendonca, DA; Paravastu, SC, 2013) |
| "The Cochrane Peripheral Vascular Diseases (PVD) Group searched for publications describing randomised controlled trials (RCTs) of beta blockers in PAD in their Trials Register (last searched 6 May 2008) and the Cochrane Central Register of Controlled Trials (CENTRAL) (last searched The Cochrane Library 2008, Issue 2)." | 2.44 | Beta blockers for peripheral arterial disease. ( Da Silva, A; Mendonca, D; Paravastu, SC, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (89.47) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paravastu, SC | 2 |
| Mendonca, DA | 1 |
| Da Silva, A | 2 |
| Mendonca, D | 1 |
| Clement, DL | 2 |
| Diehm, C | 1 |
| Mörl, H | 1 |
| Schettler, G | 1 |
| Bogaert, MG | 1 |
| Fogoros, RN | 1 |
| Rodger, JC | 1 |
| Sheldon, CD | 1 |
| Lerski, RA | 1 |
| Livingstone, WR | 1 |
| Brevetti, G | 1 |
| Paudice, G | 1 |
| Lavecchia, G | 1 |
| De Caprio, L | 1 |
| Ferro, G | 1 |
| D'Ascia, C | 1 |
| Orefice, U | 1 |
| Lant, AF | 1 |
| Gibbons, DO | 1 |
| Reichert, N | 1 |
| Shibolet, S | 1 |
| Adar, R | 1 |
| Gafni, J | 1 |
| Lepäntalo, M | 3 |
| Lindström, BL | 1 |
| Tötterman, KJ | 1 |
| Schaller, K | 1 |
| Koppelmann, J | 3 |
| Skawiński, S | 1 |
| Wójcikiewicz, O | 1 |
| Peiker, W | 1 |
| Friedebold, G | 2 |
2 reviews available for propranolol and Intermittent Claudication
| Article | Year |
|---|---|
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vas | 2013 |
Beta blockers for peripheral arterial disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Intermittent Claudication; Metoprolol; Peripheral Vas | 2008 |
4 trials available for propranolol and Intermittent Claudication
| Article | Year |
|---|---|
Lack of influence of propranolol and metoprolol on walking distance in patients with chronic intermittent claudication.
Topics: Chronic Disease; Exercise Test; Humans; Intermittent Claudication; Male; Metoprolol; Middle Aged; Pr | 1983 |
Controlled trial of propranolol in intermittent claudication.
Topics: Adult; Aged; Arteriosclerosis Obliterans; Clinical Trials as Topic; Humans; Intermittent Claudicatio | 1975 |
Beta blockade and intermittent claudication.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; | 1985 |
Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Heart Rate; Huma | 1985 |
13 other studies available for propranolol and Intermittent Claudication
| Article | Year |
|---|---|
Studies on the effect of alpha- and of beta-adrenergic blocking agents on the circulation in human limbs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cold Temperature; Hand; Hemodyna | 1980 |
[Effects of propranolol and metoprolol on peripheral circulation in intermittent claudication].
Topics: Aged; Humans; Hypertension; Intermittent Claudication; Male; Metoprolol; Middle Aged; Propanolamines | 1983 |
Exacerbation of intermittent claudication by propranolol.
Topics: Aged; Angina Pectoris; Humans; Intermittent Claudication; Male; Propranolol | 1980 |
Intermittent claudication complicating beta-blockade.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Female; Humans; Hypertension; Intermittent Claudicati | 1976 |
[Regional hemodynamic changes induced by muscular exercise in subjects with obliterating arteriopathy of the lower extremities: effect of beta receptor blocking].
Topics: Adrenergic beta-Antagonists; Arterial Occlusive Diseases; Female; Humans; Intermittent Claudication; | 1977 |
Beta-adrenoreceptor blocking drugs.
Topics: Humans; Intermittent Claudication; Male; Middle Aged; Propranolol | 1979 |
Letter: Intermittent claudication complicating beta-blockade.
Topics: Humans; Intermittent Claudication; Propranolol | 1976 |
Adrenoceptor blocking drugs and cold feet in intermittent claudication.
Topics: Aged; Foot; Humans; Hypertension; Intermittent Claudication; Labetalol; Male; Middle Aged; Propranol | 1986 |
[Effect of beta receptor blockaders in arterial circulation disorders of the lower extremities].
Topics: Adrenergic beta-Antagonists; Humans; Intermittent Claudication; Leg; Plethysmography; Propranolol; S | 1970 |
Skin and muscle flow during exercise in intermittent claudication.
Topics: Blood Flow Velocity; Electric Stimulation; Humans; Intermittent Claudication; Leg; Methods; Middle A | 1973 |
[Effect of Inderal on intermittent claudication in patients with obliterative arterial disease].
Topics: Adult; Aged; Arteries; Humans; Infant; Intermittent Claudication; Leg; Male; Middle Aged; Propranolo | 1971 |
[The conservative treatment of intermittent claudication by neurocirculatory regulation. Observations with the beta-receptor-blocking agent dociton].
Topics: Blood Circulation; Humans; Intermittent Claudication; Propranolol | 1968 |
[On the treatment of intermittent claudication. Clinical studies of pharmacological effects].
Topics: Aged; Exercise Therapy; Female; Humans; Intermittent Claudication; Male; Middle Aged; Propranolol | 1969 |