propranolol has been researched along with Infections, Plasmodium in 9 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of the erythrocyte stage of malaria infection on hepatic glucuronidation, biliary excretion and oxidation processes was investigated using harmol, salbutamol, taurocholate and propranolol." | 3.68 | Malaria infection impairs glucuronidation and biliary excretion by the isolated perfused rat liver. ( Ghabrial, H; Mihaly, GW; Morgan, DJ; Murdoch, RT; Smallwood, RA, 1991) |
| " Previously described THQ PFTIs had limitations of poor oral bioavailability and rapid clearance from the circulation of rodents." | 1.34 | Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase. ( Ankala, S; Barrett, LK; Bauer, KD; Bendale, P; Buckner, FS; Chakrabarti, D; Floyd, D; Gelb, MH; Hamilton, AD; Hornéy, C; Hucke, O; Lombardo, LJ; Nallan, L; Rivas, KL; Smart, BP; Strickland, C; Van Voorhis, WC; Verlinde, CL; Williams, DK; Yokoyama, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Voorhis, WC | 1 |
| Rivas, KL | 1 |
| Bendale, P | 1 |
| Nallan, L | 1 |
| Hornéy, C | 1 |
| Barrett, LK | 1 |
| Bauer, KD | 1 |
| Smart, BP | 1 |
| Ankala, S | 1 |
| Hucke, O | 1 |
| Verlinde, CL | 1 |
| Chakrabarti, D | 1 |
| Strickland, C | 1 |
| Yokoyama, K | 1 |
| Buckner, FS | 1 |
| Hamilton, AD | 1 |
| Williams, DK | 1 |
| Lombardo, LJ | 1 |
| Floyd, D | 1 |
| Gelb, MH | 1 |
| Singh, K | 1 |
| Okombo, J | 2 |
| Brunschwig, C | 1 |
| Ndubi, F | 1 |
| Barnard, L | 1 |
| Wilkinson, C | 1 |
| Njogu, PM | 1 |
| Njoroge, M | 1 |
| Laing, L | 1 |
| Machado, M | 1 |
| Prudêncio, M | 1 |
| Reader, J | 1 |
| Botha, M | 1 |
| Nondaba, S | 1 |
| Birkholtz, LM | 1 |
| Lauterbach, S | 1 |
| Churchyard, A | 1 |
| Coetzer, TL | 1 |
| Burrows, JN | 1 |
| Yeates, C | 1 |
| Denti, P | 1 |
| Wiesner, L | 2 |
| Egan, TJ | 2 |
| Wittlin, S | 1 |
| Chibale, K | 2 |
| Joshi, MC | 1 |
| Nsumiwa, S | 1 |
| Ndove, J | 1 |
| Taylor, D | 1 |
| Hunter, R | 1 |
| Shahabi, S | 1 |
| Mohammadzadeh Hajipirloo, H | 1 |
| Keramati, A | 1 |
| Hazrati Tappeh, K | 1 |
| Bozorgomid, A | 1 |
| Harrison, T | 2 |
| Samuel, BU | 1 |
| Akompong, T | 1 |
| Hamm, H | 1 |
| Mohandas, N | 2 |
| Lomasney, JW | 2 |
| Haldar, K | 2 |
| Murphy, SC | 1 |
| Hamm, HE | 1 |
| Murdoch, RT | 1 |
| Ghabrial, H | 1 |
| Mihaly, GW | 1 |
| Morgan, DJ | 1 |
| Smallwood, RA | 1 |
| Khare, S | 1 |
| Ghatak, S | 1 |
| Shoemaker, JP | 1 |
| McAllister, RG | 1 |
| Selby, JB | 1 |
| Hoffman, RV | 1 |
9 other studies available for propranolol and Infections, Plasmodium
| Article | Year |
|---|---|
Efficacy, pharmacokinetics, and metabolism of tetrahydroquinoline inhibitors of Plasmodium falciparum protein farnesyltransferase.
Topics: Animals; Antimalarials; Bile Ducts; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray | 2007 |
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model.
Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; | 2017 |
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeab | 2017 |
Evaluation of the adjuvant activity of propranolol, a Beta-adrenergic receptor antagonist, on efficacy of a malaria vaccine model in BALB/c mice.
Topics: Adjuvants, Immunologic; Adrenergic beta-Antagonists; Animals; Antibodies, Protozoan; Humans; Immunog | 2014 |
Erythrocyte G protein-coupled receptor signaling in malarial infection.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonist | 2003 |
Erythrocyte G protein as a novel target for malarial chemotherapy.
Topics: Adrenergic beta-Antagonists; Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Drug Therap | 2006 |
Malaria infection impairs glucuronidation and biliary excretion by the isolated perfused rat liver.
Topics: Albuterol; Animals; Bile; Erythrocytes; Glucuronates; Harmine; Liver; Malaria; Male; Metabolic Clear | 1991 |
Cyclic AMP level in red blood cells of Plasmodium berghei-infected Mastomys natalensis.
Topics: Animals; Cyclic AMP; Erythrocytes; Isoproterenol; Malaria; Male; Muridae; Plasmodium berghei; Propra | 1991 |
Effect of hypothyroidism on parasitemia and survival in rodent malaria.
Topics: Animals; Drug Resistance, Microbial; Erythrocyte Count; Female; Hypothyroidism; Iodine Radioisotopes | 1974 |