propranolol and Hypotension studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

Excerpt	Relevance	Reference
"Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials to inform its use are limited."	9.20	A randomized, controlled trial of oral propranolol in infantile hemangioma. ( Ballona, R; Barbarot, S; Baselga, E; Benjamin, L; Bernabeu-Wittel, J; Berul, CI; Birchall, N; Boccara, O; Boralevi, F; Buckova, H; Caceres, H; Cambazard, F; Delarue, A; Febrer Bosch, MI; Foelster-Holst, R; Frieden, IJ; Friedlander, SF; Glick, S; Grantzow, R; Guibaud, L; Heritier, S; Hoeger, P; Krol, A; Léauté-Labrèze, C; Lopez Gutierrez, JC; Mancini, AJ; Maruani, A; Mazereeuw-Hautier, J; Mehta, CR; Metz, B; Morgan, CC; Perek, D; Phillips, RJ; Pope, E; Posiunas, G; Powell, J; Prey, S; Przewratil, P; Roessler, J; Souteyrand, P; Su, J; Szalai, ZZ; Torrelo, A; Vabres, P; Valencia, AM; Voisard, JJ; Wargon, O; Wyrzykowski, D, 2015)
"To compare antianginal efficacy and tolerability of propranolol therapy in patients with stable angina pectoris and chronic hypotension (Hpts) and normotensive patients with angina of effort (Npts)."	9.11	[Propranolol treatment of effort angina in patients with arterial hypotension]. ( Borovkova, NV; Boshchenko, AA; Chernov, VI; Demochko, AV; Idrisova, EM; Karpov, RS, 2004)
"Adjunctive magnesium sulfate, in combination with propranolol, does not decrease the incidence of postoperative atrial fibrillation."	9.09	The combination of propranolol and magnesium does not prevent postoperative atrial fibrillation. ( Berger, AK; Hannan, RL; Katz, NM; Solomon, AJ; Trivedi, KK, 2000)
"The safety of oral propranolol for infantile hemangioma has not yet been studied at population level since the pediatric use marketing authorization was obtained in Europe."	7.88	Safety of Oral Propranolol for Infantile Hemangioma. ( Botrel, MA; Droitcourt, C; Dupuy, A; Garlantezec, R; Guillot, B; Happe, A; Kerbrat, S; Oger, E; Rault, C; Schleich, JM, 2018)
"Propranolol was useful as first-line or single-agent treatment of facial infantile haemangioma in Chinese children, and gave rise to minimal side-effects."	7.76	Use of propranolol in infantile haemangioma among Chinese children. ( Chan, HB; Chik, KK; Luk, CK; Tan, HY, 2010)
"Propranolol-induced hypotension is ameliorated by Intralipid infusion in this intact rabbit model."	7.74	Intralipid infusion ameliorates propranolol-induced hypotension in rabbits. ( Cave, GR; Harvey, MG, 2008)
"Propranolol has been used to attenuate reflex tachycardia during induced hypotension."	7.70	Splanchnic organ blood flow during calcitonin gene-related peptide-induced hypotension with or without propranolol in dogs. ( Inada, Y; Takeda, S; Tomaru, T, 2000)
" Pre-treatment with TCV-116, an angiotensin II AT1 receptor antagonist, or enalapril partially attenuated the reflex tachycardia induced by manidipine, but TCV-116 had almost no effect on the sinus tachycardia induced by isoproterenol."	7.69	Role of angiotensin II in reflex tachycardia during hypotension caused by a calcium channel blocker. ( Chatani, F; Sato, K; Sato, S, 1996)
"The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare."	7.67	Parenteral-verapamil-induced sustained hypotension. ( Serote, WF; Tucker, RA, 1984)
"A case of life-threatening hypotension due to sinus arrest is described in a patient in whom exercise-induced hyperkalemia developed during a stable regimen that included verapamil, propranolol, and ibuprofen."	7.67	Hypotension and sinus arrest with exercise-induced hyperkalemia and combined verapamil/propranolol therapy. ( Antman, EM; Lee, TH; Rayment, CM; Salomon, DR, 1986)
"The authors examined the effects of controlled hypotension induced with sodium nitroprusside (SNP) with and without propranolol on the cardiovascular, pulmonary, and renin-angiotensin systems in 10 consecutive anesthetized patients with kyphoscoliosis undergoing posterior spinal fusion."	7.66	Effects of propranolol on the cardiovascular and renin-angiotensin systems during hypotension produced by sodium nitroprusside in humans. ( Arnold, WP; Bedford, RF; Hakala, MW; Longnecker, DE; Marshall, WK; Miller, ED; Sussman, MD, 1981)
" Intravenous administration of naloxone (2 mg/kg) had no effect on systemic arterial blood pressure in adrenalectomized rats, suggesting that endogenous opiates were not contributing to the hypotension."	7.66	Post-adrenalectomy hypotension in rats; absence of baroreflex resetting or effect of naloxone. ( Bennett, T; Gardiner, SM, 1983)
"Opiate receptor blockade with naloxone reverses the hypotension associated with severe hemorrhage in a variety of animal models."	7.66	Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit. ( Schadt, JC; York, DH, 1982)
"-butylamino)-propoxy]-benzonitrile (Kö 136 1366) and propranolol, on regional Rb86 clearance in the dog myocardium under selective coronary hypotension were investigated."	7.65	A study of the effects of propranolol and/or K 1366 on the distribution of Rb86 clearance in the canine heart under selective coronary hypotension. ( Fukuyama, T; Kuroiwa, A; Nakagaki, O; Nakamura, M; Nose, Y; Tomoike, H, 1975)
"When used in the treatment of hypertension propranolol is at least of similar potency to bethanidine, guanethidine, and methyldopa."	7.65	Treatment of hypertension with propranolol. ( Gillam, PM; Prichard, BN, 1969)
"When propranolol was withdrawn blood pressures rapidly rose to hypertensive levels, though not to untreated levels."	6.63	Controlled trial of propranolol in hypertension. ( Cowen, KJ; Zacharias, FJ, 1970)
"Propranolol was also an effective treatment for hemangiomas in 4 patients older than 1 year of age."	5.37	Adverse effects of propranolol when used in the treatment of hemangiomas: a case series of 28 infants. ( Breugem, CC; Breur, JMPJ; de Graaf, M; Pasmans, SGMA; Raphaël, MF; Vos, M, 2011)
"Brain death was caused by severe intracranial hypertension; in the third group propranolol was first perfused intravenously."	5.31	[Propranolol protects the myocardium and prevents arterial hypotension in an experimental organ donation model]. ( Cerro Sánchez, J; Domínguez Roldán, JM; Hernández Fernández, A; Ojeda Rivero, R; Ordóñez Fernández, A, 2002)
"Pretreatment with mecamylamine (50 micrograms; i."	5.29	Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. ( Savci, V; Ulus, IH, 1996)
"Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats."	5.25	Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975)
"Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials to inform its use are limited."	5.20	A randomized, controlled trial of oral propranolol in infantile hemangioma. ( Ballona, R; Barbarot, S; Baselga, E; Benjamin, L; Bernabeu-Wittel, J; Berul, CI; Birchall, N; Boccara, O; Boralevi, F; Buckova, H; Caceres, H; Cambazard, F; Delarue, A; Febrer Bosch, MI; Foelster-Holst, R; Frieden, IJ; Friedlander, SF; Glick, S; Grantzow, R; Guibaud, L; Heritier, S; Hoeger, P; Krol, A; Léauté-Labrèze, C; Lopez Gutierrez, JC; Mancini, AJ; Maruani, A; Mazereeuw-Hautier, J; Mehta, CR; Metz, B; Morgan, CC; Perek, D; Phillips, RJ; Pope, E; Posiunas, G; Powell, J; Prey, S; Przewratil, P; Roessler, J; Souteyrand, P; Su, J; Szalai, ZZ; Torrelo, A; Vabres, P; Valencia, AM; Voisard, JJ; Wargon, O; Wyrzykowski, D, 2015)
"To compare antianginal efficacy and tolerability of propranolol therapy in patients with stable angina pectoris and chronic hypotension (Hpts) and normotensive patients with angina of effort (Npts)."	5.11	[Propranolol treatment of effort angina in patients with arterial hypotension]. ( Borovkova, NV; Boshchenko, AA; Chernov, VI; Demochko, AV; Idrisova, EM; Karpov, RS, 2004)
"Adjunctive magnesium sulfate, in combination with propranolol, does not decrease the incidence of postoperative atrial fibrillation."	5.09	The combination of propranolol and magnesium does not prevent postoperative atrial fibrillation. ( Berger, AK; Hannan, RL; Katz, NM; Solomon, AJ; Trivedi, KK, 2000)
"The safety of oral propranolol for infantile hemangioma has not yet been studied at population level since the pediatric use marketing authorization was obtained in Europe."	3.88	Safety of Oral Propranolol for Infantile Hemangioma. ( Botrel, MA; Droitcourt, C; Dupuy, A; Garlantezec, R; Guillot, B; Happe, A; Kerbrat, S; Oger, E; Rault, C; Schleich, JM, 2018)
" We hypothesize that judicious early low-dose propranolol after TBI (EPAT) will improve outcomes without altering bradycardia or hypotensive events."	3.83	Prospective evaluation of early propranolol after traumatic brain injury. ( Barmparas, G; Bloom, MB; Bukur, M; Harada, MY; Hoang, DM; Inaba, K; Ley, EJ; Margulies, DR; Murry, JS; Salim, A, 2016)
"Propranolol was useful as first-line or single-agent treatment of facial infantile haemangioma in Chinese children, and gave rise to minimal side-effects."	3.76	Use of propranolol in infantile haemangioma among Chinese children. ( Chan, HB; Chik, KK; Luk, CK; Tan, HY, 2010)
"Propranolol-induced hypotension is ameliorated by Intralipid infusion in this intact rabbit model."	3.74	Intralipid infusion ameliorates propranolol-induced hypotension in rabbits. ( Cave, GR; Harvey, MG, 2008)
"This study demonstrates that the tachycardia produced by systemic injections of the beta-adrenoceptor agonist, isoproterenol (10 microg/kg, i."	3.70	In vivo evidence that isoproterenol may increase heart rate in the rat by mechanisms in addition to activation of cardiac beta(1)- or beta(2)-adrenoceptors. ( Lewis, SJ; Whalen, EJ, 1999)
"Propranolol has been used to attenuate reflex tachycardia during induced hypotension."	3.70	Splanchnic organ blood flow during calcitonin gene-related peptide-induced hypotension with or without propranolol in dogs. ( Inada, Y; Takeda, S; Tomaru, T, 2000)
" Pre-treatment with TCV-116, an angiotensin II AT1 receptor antagonist, or enalapril partially attenuated the reflex tachycardia induced by manidipine, but TCV-116 had almost no effect on the sinus tachycardia induced by isoproterenol."	3.69	Role of angiotensin II in reflex tachycardia during hypotension caused by a calcium channel blocker. ( Chatani, F; Sato, K; Sato, S, 1996)
"A case of refractory hypotension following propranolol overdose is reported."	3.68	Extracorporeal circulation in the management of massive propranolol overdose. ( Corke, CF; McVey, FK, 1991)
"The presenting symptoms, course, and treatment of 10 patients with severe theophylline toxicity (heart rate above 120, multifocal atrial tachycardia or premature ventricular contractions, hypotension, seizures) are described."	3.67	Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion. ( Greenberg, A; Kroboth, PD; Piraino, BH; Weiss, J, 1984)
"A case of life-threatening hypotension due to sinus arrest is described in a patient in whom exercise-induced hyperkalemia developed during a stable regimen that included verapamil, propranolol, and ibuprofen."	3.67	Hypotension and sinus arrest with exercise-induced hyperkalemia and combined verapamil/propranolol therapy. ( Antman, EM; Lee, TH; Rayment, CM; Salomon, DR, 1986)
"Our objectives were 1) to investigate the extent to which the pulmonary vascular response to increasing cardiac index after a period of hypotension and hypoperfusion (defined as reperfusion) measured in conscious dogs is altered during pentobarbital sodium anesthesia, and 2) to determine whether pentobarbital anesthesia modifies autonomic nervous system (ANS) regulation of the pulmonary circulation during reperfusion."	3.67	Pentobarbital anesthesia modifies pulmonary vasoregulation after hypoperfusion. ( Chen, BB; Clougherty, PW; Fehr, DM; Goll, HM; Murray, PA; Nyhan, DP, 1988)
" Aortic chemoreceptor responses to steady-state hypoxia (PaO2 range, 100-30 Torr) were measured (a) before and during intravenous infusion of the beta-receptor agonist, isoproterenol (0."	3.67	Adrenergic mechanisms in oxygen chemoreception in the cat aortic body. ( Lahiri, S; Matsumoto, S; McGregor, KH; Mokashi, A; Mulligan, E, 1986)
"The incidence of oral-verapamil-induced hypotension in the presence of concomitant beta-adrenergic blockade by the oral route is quite rare."	3.67	Parenteral-verapamil-induced sustained hypotension. ( Serote, WF; Tucker, RA, 1984)
"Opiate receptor blockade with naloxone reverses the hypotension associated with severe hemorrhage in a variety of animal models."	3.66	Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit. ( Schadt, JC; York, DH, 1982)
"The authors examined the effects of controlled hypotension induced with sodium nitroprusside (SNP) with and without propranolol on the cardiovascular, pulmonary, and renin-angiotensin systems in 10 consecutive anesthetized patients with kyphoscoliosis undergoing posterior spinal fusion."	3.66	Effects of propranolol on the cardiovascular and renin-angiotensin systems during hypotension produced by sodium nitroprusside in humans. ( Arnold, WP; Bedford, RF; Hakala, MW; Longnecker, DE; Marshall, WK; Miller, ED; Sussman, MD, 1981)
" Intravenous administration of naloxone (2 mg/kg) had no effect on systemic arterial blood pressure in adrenalectomized rats, suggesting that endogenous opiates were not contributing to the hypotension."	3.66	Post-adrenalectomy hypotension in rats; absence of baroreflex resetting or effect of naloxone. ( Bennett, T; Gardiner, SM, 1983)
"The records of 185 consecutive patients having myocardial revascularization were reviewed with regard to preoperative administration of propranolol and intraoperative or postoperative complications."	3.65	Propranolol therapy in patients undergoing myocardial revascularization. ( Dorney, ER; Douglas, JS; Hatcher, CR; Jones, EL; Kaplan, JA; King, SB, 1976)
"-butylamino)-propoxy]-benzonitrile (Kö 136 1366) and propranolol, on regional Rb86 clearance in the dog myocardium under selective coronary hypotension were investigated."	3.65	A study of the effects of propranolol and/or K 1366 on the distribution of Rb86 clearance in the canine heart under selective coronary hypotension. ( Fukuyama, T; Kuroiwa, A; Nakagaki, O; Nakamura, M; Nose, Y; Tomoike, H, 1975)
" Pretreatment with phenoxybenzamine, phentolamine, propranolol, or atropine did not alter the redistribution of cortical flow during hemorrhage."	3.65	Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog. ( Boonjarern, S; Ferris, TF; Mauk, RC; Stein, JH, 1973)
"When used in the treatment of hypertension propranolol is at least of similar potency to bethanidine, guanethidine, and methyldopa."	3.65	Treatment of hypertension with propranolol. ( Gillam, PM; Prichard, BN, 1969)
"Flushing and erythema are frequent skin symptoms in rosacea."	2.66	Use of beta-blockers for rosacea-associated facial erythema and flushing: A systematic review and update on proposed mode of action. ( Driessen, RJB; Logger, JGM; Olydam, JI, 2020)
"The incidences of congestive heart failure, hypotension, AV blocks and ventricular arrhythmias were not significantly more common in the control group (8 vs."	2.65	Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits. ( Berglund, U; Dahlström, U; Karlsson, E, 1980)
"When propranolol was withdrawn blood pressures rapidly rose to hypertensive levels, though not to untreated levels."	2.63	Controlled trial of propranolol in hypertension. ( Cowen, KJ; Zacharias, FJ, 1970)
" Other reported effects are toxic confusional states and psychotic reactions."	2.36	Psychiatric side effects of antihypertensive drugs other than reserpine. ( Fleminger, R; Paykel, ES; Watson, JP, 1982)
" The propranolol starting dosage was 0."	1.72	Monitoring oral propranolol for infantile hemangiomata. ( Bar, J; Bar-Ilan, E; Cleper, R; Mashiah, J; Samuelov, L; Sprecher, E, 2022)
"Hypotension was caused by a drug interaction between adrenaline and chlorpromazine through the activation of the β-adrenergic receptor and showed a dose-dependent effect."	1.40	Hemodynamic changes by drug interaction of adrenaline with chlorpromazine. ( Higuchi, H; Ishii-Maruhama, M; Maeda, S; Miyawaki, T; Tomoyasu, Y; Yabuki, A, 2014)
" A dosage of 2 mg/kg/d, is usually employed with a dosing interval of 8 hours."	1.37	[Propranolol in the treatment of infantile hemangioma: clinical effectiveness, risks, and recommendations]. ( López-Gutiérrez, JC; Ruiz-Rodriguez, R; Sánchez-Carpintero, I, 2011)
"Propranolol was also an effective treatment for hemangiomas in 4 patients older than 1 year of age."	1.37	Adverse effects of propranolol when used in the treatment of hemangiomas: a case series of 28 infants. ( Breugem, CC; Breur, JMPJ; de Graaf, M; Pasmans, SGMA; Raphaël, MF; Vos, M, 2011)
"In hexamethonium-treated rats, the blood-pressure-lowering effect of frII was almost abolished."	1.32	Medicinal plants in Suriname: hypotensive effect of Gossypium barbadense. ( Hasrat, JA; Pieters, L; Vlietinck, AJ, 2004)
"Brain death was caused by severe intracranial hypertension; in the third group propranolol was first perfused intravenously."	1.31	[Propranolol protects the myocardium and prevents arterial hypotension in an experimental organ donation model]. ( Cerro Sánchez, J; Domínguez Roldán, JM; Hernández Fernández, A; Ojeda Rivero, R; Ordóñez Fernández, A, 2002)
"Hemorrhage was induced in fasted anesthetized rats, and the reduction of blood pressure to 40 mm Hg for a duration of 30 minutes was accomplished by withdrawal or infusion of shed blood."	1.31	Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation. ( El-Maghrabi, MR; Henry, MC; Maitra, SR; Wang, S, 2000)
"When hypotension was induced after sympathetic inhibition, ApEn was increased compared with hypotension alone, whereas parasympathetic inhibition with hypotension resulted in near-zero ApEn."	1.30	Entropy measures of heart rate variation in conscious dogs. ( Estafanous, FG; Murray, PA; Palazzolo, JA, 1998)
"Pretreatment with mecamylamine (50 micrograms; i."	1.29	Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. ( Savci, V; Ulus, IH, 1996)
"propranolol treatment."	1.28	Increase in the hypotensive effect of bromocriptine induced by spinal transection in rats: contribution of spinal dopamine receptors. ( Demenge, P; Lahlou, S, 1992)
" These results suggest that propranolol in the above dosage does not significantly reduce the incidence of supraventricular tachyarrhythmias after myocardial revascularisation."	1.27	Does low-dose propranolol reduce the incidence of supraventricular tachyarrhythmias following myocardial revascularisation? A clinical study. ( Bain, WH; Nashef, SA; Shafei, H; Turner, MA, 1988)
"The hypotension was not affected by pretreatment with propranolol."	1.27	Insulin-induced hypotension and neurogenic orthostatic hypotension. ( Brown, RT; Deeter, JA; Lee, GK; Polinsky, RJ, 1986)
"dose, a tachycardia was observed in all rats following initial transient bradycardia."	1.27	Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats. ( Imai, Y; Johnston, CI; Nolan, PL, 1986)
"Pretreatment with propranolol completely prevented rebound hemodynamic events after nitroprusside."	1.27	Propranolol prevents hemodynamic and humoral events after abrupt withdrawal of nitroprusside. ( Battit, GE; Fahmy, NR; Lappas, DG; Mihelakos, PT, 1984)
"The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement."	1.26	[Medical support in surgery for pheochromocytoma]. ( Schmucki, O, 1979)
"Mortality rate from aortic ruptures was highest (43."	1.26	Relation of hemodynamics to the incidence of diethylstilbestrol-induced aortic ruptures in hypertensive and hypotensive lines of turkeys. ( Simpson, CF, 1978)
"In this model of acute renal failure, renal vasoconstriction plays an important role following the initial ischemic insult."	1.26	Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure. ( D'Agostini, RJ; Freedman, MT; Heptinstall, RH; Scott, WW; Siegelman, SS; Solez, K; Stawowy, L, 1977)
" What remains to be solved is the dosage level."	1.26	Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade. ( Kulling, P, 1982)
"A patient with Bartter's syndrome in whom the disease was recognized at 52 years of age is described."	1.26	Bartter's syndrome. Study of a 52 year old man with evidence for a defect in proximal tubular sodium reabsorption and comments on therapy. ( Falls, WF; Tomko, DK; Yeh, BP, 1976)
"When controlled hypotension is added to myocardial depression, aortic dissection is inhibited completely."	1.25	Control of acute aortic dissection. ( Carney, WI; Cleveland, RJ; Rheinlander, HF, 1975)
"Propranolol was demonstrated to block hydralazine-induced increases in serum renin activity in genetically hypertensive rats."	1.25	Altered renin release and propranolol potentiation of vasodilatory drug hypotension. ( Keeton, K; Pettinger, WA, 1975)

Research

Studies (186)

Authors

Clinical Trials (3)

Trial Overview

Trial Outcomes

Interim Analysis : Complete/Nearly Complete Resolution of the Target Infantile Hemangioma at Week 24 Compared to Baseline Based on the Intra-patient Blinded Centralized Independent Qualitative Assessments of Week 24 Photographs.

Primary Analysis : Complete/Nearly Complete Resolution of the Target Infantile Hemangioma at W24 Compared to Baseline Based on the Intra-patient Blinded Centralized Independent Qualitative Assessments of W24 Photographs.

Change in Lesion Volume of the Test Medication as Evaluated by MRI Examination.

Timeframe	Studies, this research(%)	All Research%
pre-1990	137 (73.66)	18.7374
1990's	14 (7.53)	18.2507
2000's	17 (9.14)	29.6817
2010's	15 (8.06)	24.3611
2020's	3 (1.61)	2.80

Authors	Studies
Bar, J	1
Bar-Ilan, E	1
Cleper, R	1
Sprecher, E	1
Samuelov, L	1
Mashiah, J	1
Logger, JGM	1
Olydam, JI	1
Driessen, RJB	1
Hassoun-Kheir, N	1
Henig, O	1
Avni, T	1
Leibovici, L	1
Paul, M	1
Droitcourt, C	1
Kerbrat, S	1
Rault, C	1
Botrel, MA	1
Happe, A	1
Garlantezec, R	1
Guillot, B	1
Schleich, JM	1
Oger, E	1
Dupuy, A	1
Ogiwara, K	1
Yasumura, R	1
Kobayashi, Y	1
Novoa, M	1
Baselga, E	2
Beltran, S	1
Giraldo, L	1
Shahbaz, A	1
Pardo-Hernandez, H	1
Arevalo-Rodriguez, I	1
Orozco, BS	1
Engebretsen, KM	1
Holger, JS	1
Stellpflug, SJ	1
Iwai, T	1
Kaneko, M	1
Sasaki-Hamada, S	1
Oka, J	1
Eme, J	1
Rhen, T	1
Crossley, DA	1
Higuchi, H	1
Yabuki, A	1
Ishii-Maruhama, M	1
Tomoyasu, Y	1
Maeda, S	1
Miyawaki, T	1
Léauté-Labrèze, C	1
Hoeger, P	1
Mazereeuw-Hautier, J	1
Guibaud, L	1
Posiunas, G	1
Phillips, RJ	1
Caceres, H	1
Lopez Gutierrez, JC	1
Ballona, R	1
Friedlander, SF	1
Powell, J	1
Perek, D	1
Metz, B	1
Barbarot, S	1
Maruani, A	1
Szalai, ZZ	1
Krol, A	1
Boccara, O	1
Foelster-Holst, R	1
Febrer Bosch, MI	1
Su, J	1
Buckova, H	1
Torrelo, A	1
Cambazard, F	1
Grantzow, R	1
Wargon, O	1
Wyrzykowski, D	1
Roessler, J	1
Bernabeu-Wittel, J	1
Valencia, AM	1
Przewratil, P	1
Glick, S	1
Pope, E	1
Birchall, N	1
Benjamin, L	1
Mancini, AJ	1
Vabres, P	1
Souteyrand, P	1
Frieden, IJ	1
Berul, CI	1
Mehta, CR	1
Prey, S	1
Boralevi, F	1
Morgan, CC	1
Heritier, S	1
Delarue, A	1
Voisard, JJ	1
Murry, JS	1
Hoang, DM	1
Barmparas, G	1
Harada, MY	1
Bukur, M	1
Bloom, MB	1
Inaba, K	1
Margulies, DR	1
Salim, A	1
Ley, EJ	1
Lamb, L	1
Lowe, D	1
Gardiner, M	1
Ruttan, TK	1
Kienstra, AJ	1
Wilkinson, M	1
Steib, CJ	1
Gerbes, AL	1
Harvey, MG	1
Cave, GR	1
Chik, KK	1
Luk, CK	1
Chan, HB	1
Tan, HY	1
de Graaf, M	1
Breur, JMPJ	1
Raphaël, MF	1
Vos, M	1
Breugem, CC	1
Pasmans, SGMA	1
Sánchez-Carpintero, I	1
Ruiz-Rodriguez, R	1
López-Gutiérrez, JC	1
Ojeda Rivero, R	1
Cerro Sánchez, J	1
Ordóñez Fernández, A	1
Domínguez Roldán, JM	1
Hernández Fernández, A	1
Venon, WD	1
Baronio, M	1
Leone, N	1
Rolfo, E	1
Fadda, M	1
Barletti, C	1
Todros, L	1
Saracco, G	1
Rizzetto, M	1
SLOMAN, G	1
ROBINSON, JS	1
MCLEAN, K	1
Nammi, S	1
Gudavalli, R	1
Babu, BS	1
Lodagala, DS	1
Boini, KM	1
Höcht, C	1
Opezzo, JA	1
Taira, CA	1
Hasrat, JA	1
Pieters, L	1
Vlietinck, AJ	1
Idrisova, EM	1
Boshchenko, AA	1
Borovkova, NV	1
Demochko, AV	1
Chernov, VI	1
Karpov, RS	1
Gibson, CA	1
Stewart, JT	1
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Trial	Phase	Enrollment	Study Type	Start Date	Status
A Randomised, Controlled, Multidose, Multicentre, Adaptive Phase II/III Study in Infants With Proliferating Infantile Hemangiomas (IHs) Requiring Systemic Therapy to Compare 4 Regimens of Propranolol (1 or 3 mg/kg/Day for 3 or 6 Months) to Placebo (Double[NCT01056341]	Phase 2/Phase 3	512 participants (Actual)	Interventional	2010-01-31	Completed
Natural Berry Extract Treatment of Hemangiomas[NCT04020419]	Early Phase 1	12 participants (Actual)	Interventional	2020-12-01	Terminated (stopped due to Study ending early due to program transferring to another site.)
Phase 2 Study of Sildenafil for the Treatment of Lymphatic Malformations[NCT02335242]	Phase 2	22 participants (Actual)	Interventional	2015-05-23	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Intervention	percentage of participants (Number)
Placebo	8.0
Propranolol 1mg/kg/d 3 Months	9.8
Propranolol 1 mg/kg/d 6 Months	37.5
Propranolol 3 mg/kg/d 3 Months	7.7
Propranolol 3 mg/kg/d 6 Months	62.8

Intervention	percentage of participants (Number)
Placebo	3.6
Propranolol 3mg/kg/d 6 Months	60.4

Participants will be followed for the duration of the study, an expected average of 20 weeks. (NCT02335242)
Timeframe: Baseline, week 20

Change in Subject's Assessment of Change in Lymphatic Malformation Overall Score

Intervention	percentage of volume (Mean)
Double-Blind Placebo	5.89
Open-Label Sildenafil	-8.54
Double-blind Sildenafil	-0.642

"Subject's evaluation of the overall change in lymphatic malformation. Participants will be followed from baseline to 20 weeks.~Patients rated change as no improvement, minimal improvement (1-25% change), fair improvement (25-50% change), good improvement (50-75% change), and excellent improvement (75-100% change)." (NCT02335242)
Timeframe: Baseline, week 20

Intervention	Participants (Count of Participants)
	No improvement	Minimal improvement	Fair improvement	Good improvement	Excellent improvement
Double-Blind Placebo	1	2	0	2	0
Double-Blind Sildenafil	2	4	1	1	0

Article	Year
Use of beta-blockers for rosacea-associated facial erythema and flushing: A systematic review and update on proposed mode of action. Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:4 Topics: Administration, Oral; Adrenergic beta-Antagonists; Bradycardia; Carvedilol; Dermatologic Agents; Dru	2020
The Effect of β-Blockers for Burn Patients on Clinical Outcomes: Systematic Review and Meta-Analysis. Journal of intensive care medicine, 2021, Volume: 36, Issue:8 Topics: Adrenergic beta-Antagonists; Adult; Arrhythmias, Cardiac; Burns; Child; Humans; Hypotension; Propran	2021
Interventions for infantile haemangiomas of the skin: abridged Cochrane systematic review and GRADE assessments. The British journal of dermatology, 2019, Volume: 180, Issue:3 Topics: Administration, Cutaneous; Administration, Oral; Adrenergic beta-Antagonists; Bradycardia; GRADE App	2019
[Guidelines for the treatment of acute chemical poisoning-11-symptomatic therapy 4. Management of circulation for drug overdose and poisoning]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2007, Volume: 20, Issue:1 Topics: Acute Disease; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Cardiac	2007
Psychiatric side effects of antihypertensive drugs other than reserpine. Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:1 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin;	1982
[Syncope of undetermined nature after electrophysiologic study. Usefulness of the head-up tilt test in the diagnosis of vaso-vagal origin and in the choice of treatment]. Giornale italiano di cardiologia, 1990, Volume: 20, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atropine; Bradycardia; Electrophysiology; Etilefrine; Ev	1990
Adverse reactions to beta-adrenergic receptor blocking drugs: a report from the Boston collaborative drug surveillance program. Drugs, 1974, Volume: 7, Issue:1 Topics: Adrenergic beta-Antagonists; Bradycardia; Central Nervous System; Depression; Heart; Heart Failure;	1974
Vasodilators.. The Practitioner, 1974, Volume: 213, Issue:1276 SPEC Topics: Adrenergic alpha-Antagonists; Aminophylline; Angina Pectoris; Bradycardia; Bronchial Diseases; Cereb	1974
Therapy of common arrhythmias. The Medical clinics of North America, 1974, Volume: 58, Issue:5 Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Digitalis Glycosides;	1974
Management of arrhythmias in acute myocardial infarction. American family physician, 1971, Volume: 4, Issue:1 Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O	1971

Article	Year
A randomized, controlled trial of oral propranolol in infantile hemangioma. The New England journal of medicine, 2015, Feb-19, Volume: 372, Issue:8 Topics: Administration, Oral; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Double-Blind Me	2015
A randomized, controlled trial of oral propranolol in infantile hemangioma. The New England journal of medicine, 2015, Feb-19, Volume: 372, Issue:8 Topics: Administration, Oral; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Double-Blind Me	2015
A randomized, controlled trial of oral propranolol in infantile hemangioma. The New England journal of medicine, 2015, Feb-19, Volume: 372, Issue:8 Topics: Administration, Oral; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Double-Blind Me	2015
A randomized, controlled trial of oral propranolol in infantile hemangioma. The New England journal of medicine, 2015, Feb-19, Volume: 372, Issue:8 Topics: Administration, Oral; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Double-Blind Me	2015
Effects of long-term Irbesartan in reducing portal pressure in cirrhotic patients: comparison with propranolol in a randomised controlled study. Journal of hepatology, 2003, Volume: 38, Issue:4 Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pr	2003
[Propranolol treatment of effort angina in patients with arterial hypotension]. Terapevticheskii arkhiv, 2004, Volume: 76, Issue:8 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Drug Resistance; Drug Tolerance; Heart	2004
Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits. Acta medica Scandinavica, 1980, Volume: 207, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Femal	1980
The combination of propranolol and magnesium does not prevent postoperative atrial fibrillation. The Annals of thoracic surgery, 2000, Volume: 69, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Coro	2000
Propranolol in acute myocardial infarction. A multicentre trial. Lancet (London, England), 1966, Dec-31, Volume: 2, Issue:7479 Topics: Adult; Aged; Clinical Trials as Topic; Female; Heart Arrest; Heart Failure; Humans; Hypotension; Mal	1966
A controlled trial of propranolol in acute myocardial infarction. American heart journal, 1967, Volume: 74, Issue:4 Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Hypotension; Male; Middle Aged; Myocardial In	1967
Controlled trial of propranolol in hypertension. British medical journal, 1970, Feb-21, Volume: 1, Issue:5694 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Hypotension; Ma	1970
Anaesthesia for laryngoscopy. A comparison of the cardiovascular effects of cocaine and lignocaine. Anaesthesia, 1968, Volume: 23, Issue:2 Topics: Aged; Anesthesia, Intravenous; Anesthesia, Local; Cardiovascular System; Cocaine; Heart; Heart Rate;	1968

Article	Year
Monitoring oral propranolol for infantile hemangiomata. Dermatologic therapy, 2022, Volume: 35, Issue:11 Topics: Administration, Oral; Adrenergic beta-Antagonists; Bradycardia; Child; Hemangioma, Capillary; Humans	2022
Safety of Oral Propranolol for Infantile Hemangioma. Pediatrics, 2018, Volume: 141, Issue:6 Topics: Administration, Oral; Bradycardia; Bronchitis; Child, Preschool; Cohort Studies; Databases, Factual;	2018
[Hyperthyroidism Diagnosed from Refractory Tachycardia and Hypotension during Surgery: A Case Report]. Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:12 Topics: Blood Pressure; Female; Heart Rate; Humans; Hyperthyroidism; Hypotension; Injections, Intravenous; M	2016
A Swine Model of Severe Propranolol Toxicity Permitting Direct Measurement of Brain Tissue Oxygenation. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2019, Volume: 15, Issue:3 Topics: Animals; Arterial Pressure; Brain; Hypotension; Oxygen; Pilot Projects; Propranolol; Swine	2019
Characterization of the hypotensive effects of glucagon-like peptide-2 in anesthetized rats. Neuroscience letters, 2013, Aug-29, Volume: 550 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Atropine; Glucagon-Like Peptide 2; Hypotension;	2013
Adjustments in cholinergic, adrenergic and purinergic control of cardiovascular function in snapping turtle embryos (Chelydra serpentina) incubated in chronic hypoxia. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2014, Volume: 184, Issue:7 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Bradycardia; DNA, Comp	2014
Hemodynamic changes by drug interaction of adrenaline with chlorpromazine. Anesthesia progress, 2014,Winter, Volume: 61, Issue:4 Topics: Animals; Antipsychotic Agents; Arterial Pressure; Catheterization, Peripheral; Chlorpromazine; Dose-	2014
Prospective evaluation of early propranolol after traumatic brain injury. The Journal of surgical research, 2016, Volume: 200, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Aged; Bradycardia; Brain Injuries; Drug Administration Schedule;	2016
A new urticarial rash, diarrhoea and refractory hypotension in a man with a history of migraines. Clinical medicine (London, England), 2016, Volume: 16, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Anaphylaxis; Diagnosis, Differential; Diarrhea; Humans; Hypotens	2016
Making the Quick Diagnosis: A Case of Neonatal Shock. The Journal of emergency medicine, 2017, Volume: 52, Issue:4 Topics: Acidosis; Acyclovir; Adenosine; Ampicillin; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antiviral	2017
Secondary prophylaxis for variceal bleeding: carvedilol vs. propranolol. Hepatology international, 2017, Volume: 11, Issue:2 Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Drug Monitoring; Esophageal and	2017
Intralipid infusion ameliorates propranolol-induced hypotension in rabbits. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:2 Topics: Adrenergic beta-Antagonists; Animals; Antidotes; Blood Pressure; Disease Models, Animal; Fat Emulsio	2008
Use of propranolol in infantile haemangioma among Chinese children. Hong Kong medical journal = Xianggang yi xue za zhi, 2010, Volume: 16, Issue:5 Topics: Administration, Oral; Adrenergic beta-Antagonists; Child, Preschool; Dose-Response Relationship, Dru	2010
Adverse effects of propranolol when used in the treatment of hemangiomas: a case series of 28 infants. Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:2 Topics: Adrenergic beta-Antagonists; Biopsy, Needle; Bronchial Hyperreactivity; Cohort Studies; Dose-Respons	2011
[Propranolol in the treatment of infantile hemangioma: clinical effectiveness, risks, and recommendations]. Actas dermo-sifiliograficas, 2011, Volume: 102, Issue:10 Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Bradycardia; Bronchial Spasm; Clinical Trials	2011
[Propranolol protects the myocardium and prevents arterial hypotension in an experimental organ donation model]. Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Biomarkers; Brain Death; Catecholamines; Catheterization; Cran	2002
PROPRANOLOL (INDERAL) IN PERSISTENT VENTRICULAR FIBRILLATION. British medical journal, 1965, Apr-03, Volume: 1, Issue:5439 Topics: Digitalis Glycosides; Drug Therapy; Electric Countershock; Heart Arrest; Heart Failure; Heart Massag	1965
Possible mechanisms of hypotension produced 70% alcoholic extract of Terminalia arjuna (L.) in anaesthetized dogs. BMC complementary and alternative medicine, 2003, Oct-16, Volume: 3 Topics: Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Hypotension; Injections, Intraven	2003
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats. Pharmacological research, 2004, Volume: 49, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aorti	2004
Medicinal plants in Suriname: hypotensive effect of Gossypium barbadense. The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:3 Topics: Animals; Atropine; Dose-Response Relationship, Drug; Drug Synergism; Gossypium; Guinea Pigs; Hexamet	2004
Treatment of psychogenic polydipsia with pindolol. Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:1 Topics: Adrenergic beta-Antagonists; Antipsychotic Agents; Drinking Behavior; Humans; Hypotension; Male; Mid	2006
Cardiovascular effects of centrally acting orexin A in haemorrhage-shocked rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 11 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiovascular S	2006
Calcitonin gene-related peptide-evoked sustained tachycardia in calcitonin receptor-like receptor transgenic mice is mediated by sympathetic activity. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4 Topics: Adrenergic beta-Antagonists; Adrenomedullin; Animals; Blood Pressure; Calcitonin Gene-Related Peptid	2007
Propranolol in hypotensive anaesthesia. Anaesthesia, 1967, Volume: 22, Issue:1 Topics: Adult; Anesthesia, Endotracheal; Female; Heart Rate; Humans; Hypotension; Male; Middle Aged; Pentoli	1967
Effect of propranolol on arterial hypotension induced by halothane in the dog under nitrous oxide anaesthesia. British journal of anaesthesia, 1967, Volume: 39, Issue:3 Topics: Anesthesia, Inhalation; Animals; Dogs; Electric Countershock; Epinephrine; Halothane; Hypotension; M	1967
Effect of adrenergic blockade on consequences of sustained epinephrine infusion. Journal of applied physiology, 1967, Volume: 23, Issue:2 Topics: Animals; Blood; Blood Glucose; Carbon Dioxide; Dexamethasone; Epinephrine; Hematocrit; Hydrocortison	1967
Use of a beta adrenergic receptor blocking agent (propranolol) in the treatment of cardiac arrhythmias. The American journal of medicine, 1967, Volume: 43, Issue:2 Topics: Arrhythmias, Cardiac; Digitalis Glycosides; Electrocardiography; Humans; Hypotension; Injections, In	1967
Central mechanisms of the isoprenaline-induced hypotension in anesthetized and conscious rats. General pharmacology, 1984, Volume: 15, Issue:6 Topics: Anesthesia; Animals; Consciousness; Hypotension; Injections, Intraventricular; Isoproterenol; Male;	1984
Anaesthetic problems associated with the treatment of cardiovascular disease: II. Beta-adrenergic antagonists. Canadian Anaesthetists' Society journal, 1981, Volume: 28, Issue:2 Topics: Adrenergic beta-Antagonists; Anesthesia; Bradycardia; Cardiovascular Diseases; Drug Interactions; Hu	1981
Reflex mechanisms responsible for early spontaneous termination of paroxysmal supraventricular tachycardia. The American journal of cardiology, 1982, Feb-01, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Aged; Atropine; Blood Pressure; Electric Stimulation; Electrocar	1982
Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Cardiac Catheterizat	1982
Pheochromocytoma with asymmetric septal hypertrophy: conflicting therapies confronting anesthesiologists. Southern medical journal, 1984, Volume: 77, Issue:4 Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Anesthesia; Cardiomyopathy, Hypertroph	1984
Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit. Journal of the autonomic nervous system, 1982, Volume: 6, Issue:2 Topics: Adrenergic Fibers; Animals; Atropine; Blood Pressure; Efferent Pathways; Heart Rate; Hemodynamics; H	1982
Post-adrenalectomy hypotension in rats; absence of baroreflex resetting or effect of naloxone. Clinical science (London, England : 1979), 1983, Volume: 64, Issue:4 Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Nitroglyc	1983
Propranolol prevents hemodynamic and humoral events after abrupt withdrawal of nitroprusside. Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:4 Topics: Adolescent; Adult; Analysis of Variance; Carbon Dioxide; Dopamine; Drug Evaluation; Epinephrine; Fem	1984
Lack of histamine involvement in parathyroid hormone hypotensive action. Pharmacology, 1981, Volume: 22, Issue:5 Topics: Animals; Blood Pressure; Cimetidine; Dimaprit; Female; Histamine; Hypotension; Male; p-Methoxy-N-met	1981
Use of beta-blockade and hemoperfusion for acute theophylline poisoning. The Western journal of medicine, 1984, Volume: 141, Issue:4 Topics: Adolescent; Adult; Animals; Blood Chemical Analysis; Dogs; Female; Hemoperfusion; Humans; Hypotensio	1984
Build a "beta" mousetrap--propranolol poisoning. North Carolina medical journal, 1984, Volume: 45, Issue:3 Topics: Bradycardia; Glucagon; Heart Rate; Humans; Hypotension; Myocardial Contraction; Propranolol	1984
Hypotension in fetal and newborn lambs; different patterns of reflex heart rate control revealed by autonomic blockade. Biology of the neonate, 1983, Volume: 44, Issue:6 Topics: Animals; Animals, Newborn; Atropine; Female; Fetal Heart; Heart Rate; Hypotension; Pregnancy; Propra	1983
Calcium infusion for reversal of adverse effects of intravenous verapamil. JAMA, 1983, Jun-17, Volume: 249, Issue:23 Topics: Bradycardia; Calcium Chloride; Cardiomyopathy, Hypertrophic; Drug Synergism; Female; Humans; Hypoten	1983
Parenteral-verapamil-induced sustained hypotension. Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:3 Topics: Dopamine; Drug Interactions; Humans; Hypotension; Injections, Intravenous; Male; Middle Aged; Propra	1984
Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion. The American journal of medicine, 1984, Volume: 76, Issue:5 Topics: Aged; Heart Rate; Hemoperfusion; Humans; Hypotension; Kinetics; Male; Middle Aged; Propranolol; Seiz	1984
Hypotension and cardiopulmonary arrest associated with concurrent haloperidol and propranolol therapy. JAMA, 1984, Jul-06, Volume: 252, Issue:1 Topics: Drug Interactions; Female; Haloperidol; Heart Arrest; Humans; Hypotension; Middle Aged; Propranolol	1984
Adverse interaction between nifedipine and beta-blockade. British medical journal (Clinical research ed.), 1981, Jan-17, Volume: 282, Issue:6259 Topics: Drug Interactions; Humans; Hypotension; Male; Middle Aged; Myocardial Infarction; Nifedipine; Propra	1981
Hormonal and hemodynamic changes induced by pentolinium and propranolol during surgical correction of scoliosis. Anesthesiology, 1980, Volume: 53, Issue:2 Topics: Adolescent; Angiotensin II; Blood Pressure; Child; Epinephrine; Female; Hemodynamics; Humans; Hydrog	1980
Effects of propranolol on the cardiovascular and renin-angiotensin systems during hypotension produced by sodium nitroprusside in humans. Anesthesiology, 1981, Volume: 55, Issue:3 Topics: Adolescent; Adult; Angiotensins; Cardiovascular System; Humans; Hypotension; Lung; Nitroprusside; Pr	1981
Hypotension and thirst in rats after phentolamine treatment. Physiology & behavior, 1981, Volume: 27, Issue:3 Topics: Animals; Blood Pressure; Drinking; Drug Antagonism; Hypotension; Male; Nephrectomy; Phentolamine; Pr	1981
Cardiac drug overdose. American family physician, 1982, Volume: 25, Issue:1 Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin;	1982
Baroreflex control of heart rate in humans during nitroprusside-induced hypotension. The American journal of physiology, 1982, Volume: 243, Issue:1 Topics: Adult; Atropine; Blood Pressure; Ferricyanides; Heart Rate; Humans; Hypotension; Middle Aged; Nitrop	1982
[Complications after intravenous administration of anti-arrhythmia agents]. Kardiologiia, 1982, Volume: 22, Issue:11 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Ad	1982
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats. Clinical and experimental hypertension, 1981, Volume: 3, Issue:2 Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hyd	1981
[Standard therapy of acute myocardial infarction.--II. Management of hemodynamic complications. (author's transl)]. Herz, 1981, Volume: 6, Issue:1 Topics: Analgesics; Atropine; Digoxin; Dobutamine; Dopamine; Drug Therapy, Combination; Heart Failure; Heart	1981
Propranolol intoxication. A severe case responding to norepinephrine therapy. Archives of internal medicine, 1981, Volume: 141, Issue:6 Topics: Coma; Female; Half-Life; Humans; Hypotension; Isoproterenol; Middle Aged; Norepinephrine; Propranolo	1981
Regulation of adrenal blood flow: response to hemorrhagic hypotension. The American journal of physiology, 1981, Volume: 241, Issue:6 Topics: Adrenal Glands; Animals; Blood Pressure; Dogs; Female; Hemorrhage; Histamine; Homeostasis; Hypophyse	1981
Effect of propranolol on plasma norepinephrine during sodium nitroprusside-induced hypotension. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2 Topics: Adult; Blood Pressure; Ferricyanides; Heart Rate; Humans; Hypotension; Middle Aged; Nitroprusside; N	1980
Propranolol overdose. Annals of emergency medicine, 1980, Volume: 9, Issue:1 Topics: Adult; Emergencies; Female; Glucagon; Humans; Hypotension; Myocardial Contraction; Propranolol; Shoc	1980
Paroxysmal hypotension associated with sympathetic withdrawal. A new disorder of autonomic vasomotor regulation. Circulation, 1980, Volume: 62, Issue:4 Topics: Atropine; Autonomic Nervous System Diseases; Blood Pressure; Cardiac Pacing, Artificial; Catecholami	1980
Brain atriopeptin mediates AV3V depressor response. Peptides, 1994, Volume: 15, Issue:6 Topics: Animals; Atrial Natriuretic Factor; Atropine Derivatives; Blood Pressure; Cerebral Ventricles; Drug	1994
A comparison of combined amrinone and glucagon therapy to glucagon alone for cardiovascular depression associated with propranolol toxicity in a canine model. The American journal of emergency medicine, 1993, Volume: 11, Issue:4 Topics: Amrinone; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Depression, Chemical; Dogs;	1993
Role of angiotensin II in reflex tachycardia during hypotension caused by a calcium channel blocker. Clinical and experimental hypertension (New York, N.Y. : 1993), 1996, Volume: 18, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles;	1996
Central choline reverses hypotension caused by alpha-adrenoceptor or ganglion blockade in rats: the role of vasopressin. European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Blood Pres	1996
Entropy measures of heart rate variation in conscious dogs. The American journal of physiology, 1998, Volume: 274, Issue:4 Topics: Animals; Atropine; Dogs; Drug Combinations; Entropy; Heart Rate; Hypotension; Parasympatholytics; Po	1998
Endogenous angiotensin II and bradykinin delay and attenuate the hypotension after N-type calcium channel blockade in conscious rabbits. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti	1998
Activation by Phoneutria nigriventer spider venom of autonomic nerve fibers in the isolated rat heart. European journal of pharmacology, 1998, Dec-18, Volume: 363, Issue:2-3 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Arachnid	1998
In vivo evidence that isoproterenol may increase heart rate in the rat by mechanisms in addition to activation of cardiac beta(1)- or beta(2)-adrenoceptors. European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Biological Clocks; Drug In	1999
Carvedilol--A new nonselective beta blocker. Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:3 Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Hemodynamics; Humans; Hypotension; Liver Cirrho	2000
Propanolol administration in a patient with thyroid storm. Annals of internal medicine, 2000, Apr-18, Volume: 132, Issue:8 Topics: Adrenergic beta-Antagonists; Female; Graves Disease; Heart Diseases; Humans; Hypotension; Middle Age	2000
Splanchnic organ blood flow during calcitonin gene-related peptide-induced hypotension with or without propranolol in dogs. Anesthesia and analgesia, 2000, Volume: 90, Issue:6 Topics: Adrenergic beta-Antagonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressur	2000
Effect of the dry-cold season dormancy on the tonic and phasic neural control of heart rate in the toad, Bufo paracnemis. The Journal of experimental zoology, 2000, Jun-15, Volume: 287, Issue:1 Topics: Adrenergic Fibers; Animals; Autonomic Nerve Block; Blood Pressure; Bufonidae; Cholinergic Fibers; El	2000
Regulation of liver and kidney glucose-6-phosphatase gene expression in hemorrhage and resuscitation. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2000, Volume: 7, Issue:7 Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Northern; Disease Models, Animal; Gene Expre	2000
Arteriovenous difference of plasma osmolality and osmoactive substances in the hind limb of dogs under hemorrhagic hypotension--special reference to endogenous catecholamine--. Japanese circulation journal, 1977, Volume: 41, Issue:6 Topics: Animals; Arteries; Bicarbonates; Blood; Blood Glucose; Blood Pressure; Bloodletting; Catecholamines;	1977
Adrenergic theory: application to clinical and experimental surgery. The American surgeon, 1975, Volume: 41, Issue:4 Topics: Adrenergic Agents; Adrenergic Agonists; Adrenergic alpha-Antagonists; Angina Pectoris; Aortic Valve	1975
Fluid transfer from skeletal muscle to blood during hemorrhage. Importance of beta adrenergic vascular mechanisms. Acta physiologica Scandinavica, 1978, Volume: 102, Issue:4 Topics: Animals; Blood Pressure; Capillary Permeability; Cats; Female; Hemorrhage; Hypotension; Male; Muscle	1978
[Adrenergic beta receptor blockaders]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Feb-28, Volume: 95, Issue:6 Topics: Adrenergic beta-Antagonists; Anesthesia; Asthma; Bronchial Spasm; Conjunctivitis; Hypoglycemia; Hypo	1975
Altered renin release and propranolol potentiation of vasodilatory drug hypotension. The Journal of clinical investigation, 1975, Volume: 55, Issue:2 Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dose-Response	1975
PLasma glucagon levels during rapid exsanguination with and without adrenergic blockade. Diabetes, 1975, Volume: 24, Issue:4 Topics: Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Glucagon; Hemorrhage; Hypotension; Insuli	1975
A study of the effects of propranolol and/or K 1366 on the distribution of Rb86 clearance in the canine heart under selective coronary hypotension. Arzneimittel-Forschung, 1975, Volume: 25, Issue:5 Topics: Animals; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Heart Rate; Hypotension; Myoca	1975
[Central and peripheral mechanisms of hypotension induced by dl-propranolol in the dog]. Acta physiologica latino americana, 1978, Volume: 28, Issue:6 Topics: Animals; Blood Pressure; Carotid Arteries; Dogs; Electric Stimulation; Epinephrine; Hypotension; Inj	1978
Immediate and delayed hypotensive effects of propranolol at rest and during exercise. Transactions of the Association of American Physicians, 1979, Volume: 92 Topics: Blood Pressure; Female; Heart Rate; Humans; Hypotension; Male; Middle Aged; Norepinephrine; Physical	1979
[Reduction of efferent renal nerve activity by propranolol in rabbits]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1977, May-09, Volume: 284, Issue:18 Topics: Animals; Blood Pressure; Bloodletting; Hypotension; Kidney; Membrane Potentials; Neurons, Efferent;	1977
Factitious bradycardia and hypotension due to surreptitious ingestion of propranolol. Chest, 1979, Volume: 75, Issue:6 Topics: Adult; Bradycardia; Female; Humans; Hypotension; Propranolol; Self Medication	1979
Mechanisms of renin secretion during hemorrhage in the dog. The Journal of clinical investigation, 1979, Volume: 64, Issue:1 Topics: Animals; Dogs; Hemodynamics; Hemorrhage; Hypotension; Indomethacin; Kidney; Natriuresis; Perfusion;	1979
[Medical support in surgery for pheochromocytoma]. Helvetica chirurgica acta, 1979, Volume: 46, Issue:3 Topics: Adrenal Gland Neoplasms; Arrhythmias, Cardiac; Humans; Hypertension; Hypotension; Intraoperative Com	1979
Relation of hemodynamics to the incidence of diethylstilbestrol-induced aortic ruptures in hypertensive and hypotensive lines of turkeys. Atherosclerosis, 1978, Volume: 30, Issue:4 Topics: Animals; Aorta, Abdominal; Aortic Rupture; Cholesterol; Diethylstilbestrol; Hemodynamics; Hypertensi	1978
Hypotensive effect of propranolol and phenoperidine in tetanus. British medical journal, 1978, Oct-21, Volume: 2, Issue:6145 Topics: Aged; Humans; Hypotension; Male; Phenoperidine; Propranolol; Tetanus	1978
Doxorubicin-induced hypotension in the beagle dog. Agents and actions, 1978, Volume: 8, Issue:5 Topics: Animals; Atropine; Dogs; Doxorubicin; Histamine; Histamine Antagonists; Hypotension; Propranolol	1978
Inhibition of propranolol metabolism by chlorpromazine. Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:1 Topics: Adult; Chlorpromazine; Drug Interactions; Humans; Hypotension; Isoproterenol; Kinetics; Male; Propra	1979
Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure. The American journal of pathology, 1977, Volume: 88, Issue:1 Topics: Acute Kidney Injury; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Drink	1977
Attempted suicide with 5.1 g of propranolol. A case report. Acta medica Scandinavica, 1976, Volume: 199, Issue:6 Topics: Adult; Bradycardia; Humans; Hypotension; Male; Propranolol; Suicide, Attempted	1976
Bartter's syndrome. Study of a 52 year old man with evidence for a defect in proximal tubular sodium reabsorption and comments on therapy. The American journal of medicine, 1976, Volume: 61, Issue:1 Topics: Bartter Syndrome; Extracellular Space; Humans; Hyperaldosteronism; Hypokalemia; Hypotension; Kidney	1976
Significance of spinal autonomic loci in post coronary ligation arrhythmia. Neuropharmacology, 1976, Volume: 15, Issue:10 Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Catecholamines; Chloralose; Chlorisondamine	1976
Propranolol therapy in patients undergoing myocardial revascularization. The American journal of cardiology, 1976, Nov-23, Volume: 38, Issue:6 Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Cardiac Output; Cardiopulmonary Bypass; Coronary	1976
Efferent pathways of the coronary chemoreflex. The Journal of laboratory and clinical medicine, 1975, Volume: 85, Issue:6 Topics: Animals; Atropine; Cardiovascular System; Coronary Vessels; Dogs; Guanethidine; Hindlimb; Hypotensio	1975
Control of acute aortic dissection. Surgery, 1975, Volume: 78, Issue:1 Topics: Animals; Aorta; Aortic Aneurysm; Blood Pressure; Depression, Chemical; Disease Models, Animal; Dogs;	1975
Reversible cardiogenic shock after low dose oral propranolol. The Journal of the Kansas Medical Society, 1975, Volume: 76, Issue:11 Topics: Administration, Oral; Aged; Bradycardia; Confusion; Humans; Hypotension; Male; Middle Aged; Oliguria	1975
Increase in the hypotensive effect of bromocriptine induced by spinal transection in rats: contribution of spinal dopamine receptors. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5 Topics: Analysis of Variance; Animals; Blood Pressure; Blood-Brain Barrier; Bromocriptine; Domperidone; Hear	1992
Exacerbation of vasodepressor syncope by beta-adrenergic blockade. The New England journal of medicine, 1991, Apr-25, Volume: 324, Issue:17 Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Hypotension; Propranolol; Syncope; Vascular Resi	1991
Extracorporeal circulation in the management of massive propranolol overdose. Anaesthesia, 1991, Volume: 46, Issue:9 Topics: Adult; Drug Overdose; Extracorporeal Circulation; Female; Humans; Hypotension; Propranolol; Suicide,	1991
[Adrenoganglioplegia as a method of correction of hemodynamic disorders in surgical patients with initial hypotension]. Vestnik khirurgii imeni I. I. Grekova, 1990, Volume: 144, Issue:4 Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Digestive System Diseases; Dioxanes; Ganglion	1990
Vasodepressive carotid sinus hypersensitivity with head and neck malignancy: treatment with propranolol. American heart journal, 1991, Volume: 122, Issue:1 Pt 1 Topics: Carcinoma, Squamous Cell; Carotid Sinus; Humans; Hypotension; Laryngeal Neoplasms; Male; Middle Aged	1991
The effect of propranolol on the hyperaemic response of the hepatic artery to portal venous occlusion in the dog. British journal of pharmacology, 1989, Volume: 96, Issue:2 Topics: Animals; Dogs; Epinephrine; Female; Hemodynamics; Hemorrhage; Hepatic Artery; Hypotension; Liver Cir	1989
Mixed carotid sinus hypersensitivity: successful therapy with pacing, ephedrine, and propranolol. Pacing and clinical electrophysiology : PACE, 1985, Volume: 8, Issue:3 Pt 1 Topics: Blood Pressure; Bradycardia; Carotid Sinus; Combined Modality Therapy; Ephedrine; Heart; Heart Arres	1985
Hemodynamic recovery during simulated ventricular tachycardia: role of adrenergic receptor activation. American heart journal, 1988, Volume: 115, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiac Pacing, Artificial; Dise	1988
Pentobarbital anesthesia modifies pulmonary vasoregulation after hypoperfusion. The American journal of physiology, 1988, Volume: 255, Issue:3 Pt 2 Topics: Acetylcholine; Anesthesia, General; Animals; Autonomic Nervous System; Blood Pressure; Cardiac Outpu	1988
Does low-dose propranolol reduce the incidence of supraventricular tachyarrhythmias following myocardial revascularisation? A clinical study. The Thoracic and cardiovascular surgeon, 1988, Volume: 36, Issue:4 Topics: Adrenergic beta-Antagonists; Drug Administration Schedule; Heart Rate; Humans; Hypotension; Myocardi	1988
Bivalent ligand type beta-adrenolytics related to practolol. Drugs under experimental and clinical research, 1988, Volume: 14, Issue:9 Topics: Adrenergic beta-Antagonists; Animals; Chemical Phenomena; Chemistry; Drug Design; Female; Guinea Pig	1988
Alpha 1- and alpha 2-adrenoreceptor relationships in SHRs during hypotension. Circulatory shock, 1985, Volume: 17, Issue:2 Topics: Adrenal Medulla; Animals; Blood Pressure; Hypotension; Male; Prazosin; Pressoreceptors; Propranolol;	1985
Cardiac and coronary effects of prazosin and phenoxybenzamine during coronary hypotension. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: Animals; Coronary Circulation; Dogs; Female; Heart; Hypotension; Male; Oxygen Consumption; Phenoxybe	1986
Cardiovascular collapse after verapamil in supraventricular tachycardia. Archives of disease in childhood, 1988, Volume: 63, Issue:9 Topics: Digoxin; Drug Interactions; Humans; Hypotension; Propranolol; Tachycardia, Supraventricular; Verapam	1988
Facilitation of immunoreactive corticotropin-releasing factor secretion into the hypophysial-portal circulation after activation of catecholaminergic pathways or central norepinephrine injection. Endocrinology, 1987, Volume: 121, Issue:3 Topics: Animals; Catecholamines; Corticotropin-Releasing Hormone; Electric Stimulation; Hypotension; Hypotha	1987
Insulin-induced hypotension and neurogenic orthostatic hypotension. Neurology, 1986, Volume: 36, Issue:10 Topics: Aged; Blood Glucose; Blood Pressure; Central Nervous System Diseases; Epinephrine; Female; Heart Rat	1986
Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats. Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:2 Topics: Animals; Atropine; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypertension; Hypotension; In	1986
Hypotension and sinus arrest with exercise-induced hyperkalemia and combined verapamil/propranolol therapy. The American journal of medicine, 1986, Volume: 80, Issue:6 Topics: Drug Interactions; Heart Arrest; Humans; Hypotension; Ibuprofen; Male; Middle Aged; Physical Exertio	1986
Bradycardia and hypotension after propranolol HCl and verapamil. Heart & lung : the journal of critical care, 1985, Volume: 14, Issue:1 Topics: Bradycardia; Drug Interactions; Female; Humans; Hypotension; Middle Aged; Propranolol; Tachycardia,	1985
Adrenergic mechanisms in oxygen chemoreception in the cat aortic body. Respiration physiology, 1986, Volume: 63, Issue:3 Topics: Animals; Aortic Bodies; Biomechanical Phenomena; Cats; Chemoreceptor Cells; Female; Hypotension; Hyp	1986
Propranolol intoxication: three cases' experiences. Veterinary and human toxicology, 1985, Volume: 27, Issue:6 Topics: Adolescent; Adult; Bradycardia; Female; Glucagon; Humans; Hypotension; Isoproterenol; Propranolol; S	1985
Pharmacological studies of snake (Dendroaspis angusticeps) venom. Toxicon : official journal of the International Society on Toxinology, 1973, Volume: 11, Issue:2 Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Carotid Body; Carotid Sinus; Cats; Denervation; Di	1973
Central nervous alpha-adrenergic receptors and the mode of action of alpha-methyldopa. Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3 Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Catecholamines; Cats;	1973
Hypotension after oral propranolol. Lancet (London, England), 1968, Mar-09, Volume: 1, Issue:7541 Topics: Heart Failure; Humans; Hypotension; Male; Middle Aged; Propranolol	1968
Sympathetic and parasympathetic components of reflex tachycardia induced by hypotension in conscious dogs with and without heart failure. Cardiovascular research, 1974, Volume: 8, Issue:2 Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Dogs; Heart Failure; Heart Rate; Hypotensio	1974
Effects of hemorrhage on regional blood flow distribution in dogs and primates. The Journal of clinical investigation, 1974, Volume: 54, Issue:2 Topics: Animals; Atropine; Blood Circulation; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary	1974
Unwanted effects of propranolol. The American journal of cardiology, 1966, Volume: 18, Issue:3 Topics: Blood Cell Count; Blood Urea Nitrogen; Bradycardia; Drug Eruptions; Enzymes; Heart Failure; Humans;	1966
[Idiopathic hypotension. Pharmacological tests and therapeutic success with a pressure suit]. Deutsche medizinische Wochenschrift (1946), 1966, Nov-18, Volume: 91, Issue:46 Topics: Angiotensin II; Bandages; Blood Glucose; Blood Pressure Determination; Fludrocortisone; Humans; Hypo	1966
Angiotensin blocking actions of guancydine. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2 Topics: Angiotensin II; Animals; Atropine; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Epinephrin	1969
The relative effect of the renal pressor and sympathetic nervous systems on vascular capacity during hypotension. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:1 Topics: Anesthesia, Spinal; Angiotensin II; Animals; Blood Pressure; Dogs; Female; Hematocrit; Hemorrhage; H	1971
Uterine blood flow and uterine renin secretion. The Journal of clinical investigation, 1972, Volume: 51, Issue:11 Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Carotid Arteries; Cerium Isotopes; Female;	1972
Pharmacological observations on the hypotensive action of extracts of teleost fish Urophyses (urotensin I) in the rat. British journal of pharmacology, 1974, Volume: 51, Issue:3 Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Blood Pressure; Bradykinin; Diphenhydramine; Epine	1974
The effects of beta-adrenergic receptor blockade on the blood pressure and heart rate changes induced by noradrenaline infusion and postinfusional hypotension. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 171, Issue:1 Topics: Amino Alcohols; Animals; Arteries; Blood Pressure; Cats; Electrocardiography; Ethanolamines; Female;	1968
[Influence of hypocapnic gaseous alkalosis on beta effects of sympathomimetics]. Pathologie-biologie, 1969, Volume: 17, Issue:1 Topics: Acid-Base Equilibrium; Alkalosis; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Dogs; Ephedri	1969
The effect of alpha and beta adrenergic blockade on thoracic duct lymph flow in normovolemic and hypovolemic dogs. The American surgeon, 1969, Volume: 35, Issue:12 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood	1969
Mechanisms of change in thoracic duct lymph flow during hypotensive states. Annals of surgery, 1970, Volume: 171, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aspirin; Capillary Permeability;	1970
Cardiovascular effects of beta-receptor blocking drugs during halothane anaesthesia in man. Acta anaesthesiologica Scandinavica, 1970, Volume: 14, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Amino Alcohols; Anesthesia, Inhalation; Atropine; Blood Pressure	1970
Analysis of the central receptors concerned in the cardiovascular response induced by intracerebroventricular aconitine. Neuropharmacology, 1972, Volume: 11, Issue:1 Topics: Adrenalectomy; Adrenergic beta-Antagonists; Alkaloids; Alkalosis; Animals; Arrhythmias, Cardiac; Atr	1972
Letter: Hazard of propranolol in treatment of acute prophyria. British medical journal, 1974, Oct-05, Volume: 4, Issue:5935 Topics: Adult; Bradycardia; Female; Homeostasis; Humans; Hypotension; Porphyrias; Propranolol	1974
Dissection of the thoracic aorta. Medical or surgical therapy? The American journal of cardiology, 1974, Volume: 34, Issue:7 Topics: Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Valve Insufficiency; Autonomic Agents; Blood P	1974
New drug for schizophrenia? British medical journal, 1974, Dec-14, Volume: 4, Issue:5945 Topics: Chlorpromazine; Drug Synergism; Heart Arrest; Humans; Hypoglycemia; Hypotension; Phenothiazines; Pro	1974
Severe hypotension following intravenous propranolol in a hyperthyroid patient. Michigan medicine, 1974, Volume: 73, Issue:32 Topics: Humans; Hyperthyroidism; Hypotension; Injections, Intravenous; Male; Middle Aged; Propranolol	1974
[Problems in the establishment of indications for treatment of aortic (thoracic and abdominal) aneurysms, from a medical viewpoint (author's transl)]. Langenbecks Archiv fur Chirurgie, 1974, Volume: 337 Topics: Aged; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm; Aortic Rupture; Guanethidine; Humans; Hypo	1974
Clinical anesthesia conference. Severe hypotension following administration of propranolol hydrochloride. New York state journal of medicine, 1973, Nov-15, Volume: 73, Issue:22 Topics: Aged; Female; Humans; Hypotension; Propranolol; Tachycardia	1973
[Adverse effects of recent ventricular anti-arrhythmia drug]. La Vie medicale au Canada francais, 1972, Volume: 1, Issue:2 Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Drug Synergism; Electro	1972
[Intoxication with antiarrythmica (author's transl)]. Padiatrie und Padologie, 1972, Volume: 7, Issue:1 Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child, Preschool; Electrocardiography; Human	1972
Effects of sympathomimetic and sympatholytic agents on mesenteric hemodynamics in hemorrhagic hypotension. The Japanese journal of surgery, 1972, Volume: 2, Issue:3-4 Topics: Animals; Cardiac Output; Dogs; Epinephrine; Hemodynamics; Hemorrhage; Hypotension; Isoproterenol; Me	1972
Mechanism of the redistribution of renal cortical blood flow during hemorrhagic hypotension in the dog. The Journal of clinical investigation, 1973, Volume: 52, Issue:1 Topics: Animals; Aorta, Abdominal; Atropine; Blood Flow Velocity; Blood Pressure; Blood Transfusion, Autolog	1973
Influence of the sympathetic system on the pacemaker suppression which follows overdrive. Circulation, 1973, Volume: 48, Issue:2 Topics: Amyl Nitrite; Animals; Dogs; Electric Stimulation; Electrocardiography; Heart Block; Heart Conductio	1973
Adverse reactions to propranolol in hospitalized medical patients: a report from the Boston Collaborative Drug Surveillance Program. American heart journal, 1973, Volume: 86, Issue:4 Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Boston; Evaluation Studies as To	1973
Coexistent fixed congenital and idiopathic hypertrophic subaortic stenosis. The American journal of cardiology, 1973, Volume: 31, Issue:4 Topics: Adolescent; Aortic Valve Stenosis; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Cineangiog	1973
Transposition of the great arteries. A review of 37 cases after Mustard's operation. Thorax, 1973, Volume: 28, Issue:4 Topics: Arrhythmias, Cardiac; Child, Preschool; Digoxin; Female; Follow-Up Studies; Heart Arrest; Heart Bloc	1973
Spleen as an experimental model for the study of vascular capacitance. The American journal of physiology, 1973, Volume: 225, Issue:6 Topics: Acetylcholine; Animals; Atropine; Autonomic Agents; Blood Pressure; Blood Vessels; Dogs; Electric St	1973
[Interaction between beta receptor blockaders and verapamil]. Lakartidningen, 1973, Oct-10, Volume: 70, Issue:41 Topics: Bradycardia; Drug Interactions; Graves Disease; Humans; Hypotension; Male; Middle Aged; Propranolol;	1973
Mechanism responsible for the cardiovascular depressant. Effect of protamine sulfate. Annals of surgery, 1974, Volume: 180, Issue:2 Topics: Animals; Atropine; Blood Pressure; Bradycardia; Cardiac Output; Central Venous Pressure; Dogs; Extra	1974
[Study of rat vasomotor activity during adrenaline or noradrenaline administration. Effects of propranolol and adaptation to different temperatures]. Journal de physiologie, 1968, Volume: 60 Suppl 2 Topics: Adaptation, Physiological; Animals; Blood Pressure; Depression, Chemical; Epinephrine; Hypotension;	1968
Mechanisms of baroreceptor-induced changes in heart rate. The American journal of physiology, 1970, Volume: 218, Issue:1 Topics: Animals; Atropine; Blood Pressure; Carotid Arteries; Carotid Sinus; Dogs; Heart; Heart Rate; Hyperte	1970
[Comparative hemodynamic studies on the effect of ICI 50 172 and propranolol in man]. Zeitschrift fur Kreislaufforschung, 1972, Volume: 61, Issue:1 Topics: Acetanilides; Adult; Cardiac Output; Depression, Chemical; Female; Hemodynamics; Humans; Hypotension	1972
Precordial S-T segment elevation mapping: an atraumatic method for assessing alterations in the extent of myocardial ischemic injury. The effects of pharmacologic and hemodynamic interventions. The American journal of cardiology, 1972, Volume: 29, Issue:2 Topics: Animals; Arteries; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Rate;	1972
The peripheral circulatory effects of clonidine and their role in the production of arterial hypotension. European journal of pharmacology, 1971, Volume: 14, Issue:2 Topics: Adrenalectomy; Aniline Compounds; Animals; Atropine; Autonomic Nerve Block; Blood Pressure; Cardiac	1971
[Hemodialysis treatment of a 3 1-4-year-old child with imipramine poisoning]. Archiv fur Toxikologie, 1970, Volume: 26, Issue:2 Topics: Arrhythmias, Cardiac; Charcoal; Child, Preschool; Chloral Hydrate; Electrocardiography; Electroencep	1970
Heart rate after combined vagal and sympathetic blockade in patients with heart disease. British heart journal, 1969, Volume: 31, Issue:5 Topics: Adolescent; Adult; Atrial Fibrillation; Atropine; Female; Heart Diseases; Heart Function Tests; Hear	1969
Propranolol in the treatment of angina pectoris. Indian heart journal, 1969, Volume: 21, Issue:3 Topics: Angina Pectoris; Bradycardia; Humans; Hypotension; Propranolol; Thrombocytopenia	1969
Hypotension caused by L-dopa. British medical journal, 1970, Jul-04, Volume: 3, Issue:5713 Topics: Dihydroxyphenylalanine; Female; Humans; Hypotension; Middle Aged; Parkinson Disease; Propranolol	1970
Hypotension caused by L-dopa. British medical journal, 1970, Aug-15, Volume: 3, Issue:5719 Topics: Dihydroxyphenylalanine; Humans; Hypotension; Propranolol	1970
The generation of kinins in the blood of dogs during hypotension due to haemorrhage. Clinical science, 1970, Volume: 39, Issue:3 Topics: Animals; Arteries; Blood Pressure; Bradykinin; Cats; Central Venous Pressure; Dogs; Epinephrine; Fem	1970
[Treatment of imipramine poisoning at childhood]. Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:11 Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot	1970
[Clinical aspects of blood pressure regulation disorders]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Jul-15, Volume: 22, Issue:14 Topics: Ergotamine; Humans; Hypertension; Hypotension; Propranolol; Psychophysiologic Disorders	1967
Treatment of hypertension with propranolol. British medical journal, 1969, Jan-04, Volume: 1, Issue:5635 Topics: Blood Pressure; Cardiac Output; Female; Guanethidine; Guanidines; Humans; Hypertension; Hypotension;	1969
Combined adrenergic blockade in experimental hemorrhagic hypotension. Pflugers Archiv : European journal of physiology, 1969, Jun-24, Volume: 310, Issue:1 Topics: Animals; Blood Chemical Analysis; Blood Glucose; Blood Volume; Carbon Dioxide; Dogs; Hematocrit; Hyd	1969
The coronary attack: concepts on its etiology and hemodynamic management. American heart journal, 1969, Volume: 78, Issue:4 Topics: Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Biophysical Phenomena; Biophysics; Blood Fl	1969
Norepinephrine response in normal and hypotensive sheep. Journal of applied physiology, 1966, Volume: 21, Issue:4 Topics: Animals; Blood Pressure; Cardiac Output; Endotoxins; Femoral Artery; Hypotension; Norepinephrine; Pr	1966

propranolol and Hypotension