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propranolol and Hypertension, Portal

propranolol has been researched along with Hypertension, Portal in 328 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."9.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
"Damping index of the HV waveform by Doppler ultrasonography might be a non-invasive supplementary tool in evaluating the severity of portal hypertension and in responding to propranolol in patients with liver cirrhosis."9.12Damping index of Doppler hepatic vein waveform to assess the severity of portal hypertension and response to propranolol in liver cirrhosis: a prospective nonrandomized study. ( Baik, SK; Chang, SJ; Kim, HS; Kim, JW; Kim, MY; Kim, YJ; Kwon, SO; Lee, SS; Lim, DW; Park, DH, 2007)
"In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months."9.11Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005)
"Propranolol ameliorates thrombocytopenia in patients with cirrhosis."9.10Propranolol ameliorates thrombocytopenia in patients with cirrhosis. ( Iwao, T; Oho, K; Sakai, K; Sata, M; Toyonaga, A, 2002)
"To investigate the stereoselective metabolism of the propranolol enantiomers and its impact on portal haemodynamics in patients with liver cirrhosis since only S-propranolol is haemodynamically active."9.09Propranolol stereoisomer plasma concentrations and portal haemodynamic response in patients with liver cirrhosis. ( Brensing, K; Hoppe, A; Paar, D; Potyka, U; Raab, P; Sauerbruch, T; Schepke, M, 1999)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."9.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."9.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"This study tested the hypothesis that reduction in the hyperdynamic systemic circulation with propranolol in patients with alcoholic cirrhosis and distal splenorenal shunt would lead to improved maintenance of portal perfusion."9.07The effect of propranolol on portal perfusion in patients with alcoholic cirrhosis having distal splenorenal shunt. ( Galloway, JR; Gilmore, GT; Henderson, JM; Mackay, G, 1994)
"The aim of this study was to investigate the effect of rectal ozone on portal vein oxygenation and the pharmacokinetic changes of propranolol in patients with liver cirrhosis."7.77The effect of rectal ozone on the portal vein oxygenation and pharmacokinetics of propranolol in liver cirrhosis (a preliminary human study). ( Fouad, EA; Kotb, HI; Zaky, S, 2011)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."7.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
"In this model, pretreatment with propranolol prevented the increase in portal venous inflow, which occurs following hemorrhage and volume restitution with Haemaccel."7.71Systemic and splanchnic hemodynamics following hemorrhage and volume restitution with Haemaccel in portal hypertensive rats: the effect of propranolol. ( Arish, A; Hilzenrat, N; Sikuler, E; Yaari, A, 2001)
" Seven patients with alcoholic cirrhosis received verapamil, 10 mg i."7.67Combination of ketanserin and verapamil or propranolol in patients with alcoholic cirrhosis: search for an additive effect. ( Cerini, R; Hadengue, A; Koshy, A; Lebrec, D; Lee, SS; Moreau, R, 1989)
"The effect of long-term propranolol administration on esophageal varices, portocollateral shunting, portal pressure, hepatosplanchnic hemodynamics, and liver function was studied in a pig model with experimentally induced prehepatic portal hypertension and esophageal varices."7.67Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices. ( Jensen, LS; Juhl, CO; Krarup, N; Larsen, JA; Nielsen, TH, 1989)
"Propranolol (20 mg 4 times a day) was given to patients with liver cirrhosis or fatty infiltration of the liver."7.66Propranolol increases arterial ammonia in liver cirrhosis. ( Koorevaar, G; Silberbusch, J; van Buuren, HR; van der Velden, PC, 1982)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."6.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Tertatolol was rapidly absorbed with a Cmax of 70 +/- 51 micrograms/l at a peak time of 0."6.67Hemodynamic and pharmacokinetic study of tertatolol in patients with alcoholic cirrhosis and portal hypertension. ( Brouard, R; Caillau, H; Calès, P; Crambes, O; Desmorat, H; Jung, L; Pascal, JP; Rocher, I; Urien, S; Vinel, JP, 1993)
"No significant changes in the size of esophageal varices were observed after propranolol or placebo administration."6.67Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension. ( Bordas, JM; Bosch, J; Feu, F; Garcia-Pagán, JC; Rodés, J, 1991)
"When propranolol was administered to patients with alcoholic cirrhosis and marginal liver function, as reflected by ammonia levels above 60 microM, it caused a significant increase in ammonia levels in arterialized-venous and arterial, but not in venous, blood (p less than 0."6.66Venous, arterial, and arterialized-venous blood ammonia levels and their relationship to hepatic encephalopathy after propranolol. ( Lieber, CS; Snady, H, 1988)
"Cirrhosis recurrence is frequent after orthotopic liver transplantation for hepatitis C virus (HCV)."5.39Hemodynamic response to propranolol in patients with recurrent hepatitis C virus-related cirrhosis after liver transplantation: a case-control study. ( Abraldes, JG; Berzigotti, A; Bosch, J; Carrión, JA; Forns, X; García-Pagán, JC; García-Valdecasas, JC; Navasa, M; Schepis, F; Vukotic, R, 2013)
" A total of 94 cirrhotic patients having large oesophageal varices without history of variceal bleeding were randomized to three treatment groups and given 2 months' treatment with propranolol plus placebo, propranolol plus antibiotics (norfloxacin 400 mg BD) or propranolol plus probiotic (VSL#3, 900 billion/day) randomly assigned in 1:1:1 ratio."5.17Effects of the adjunctive probiotic VSL#3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial. ( Garg, V; Gupta, N; Kumar, A; Sarin, SK; Sharma, BC; Sharma, P, 2013)
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."5.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
"Damping index of the HV waveform by Doppler ultrasonography might be a non-invasive supplementary tool in evaluating the severity of portal hypertension and in responding to propranolol in patients with liver cirrhosis."5.12Damping index of Doppler hepatic vein waveform to assess the severity of portal hypertension and response to propranolol in liver cirrhosis: a prospective nonrandomized study. ( Baik, SK; Chang, SJ; Kim, HS; Kim, JW; Kim, MY; Kim, YJ; Kwon, SO; Lee, SS; Lim, DW; Park, DH, 2007)
"In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months."5.11Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005)
"Sixty patients with cirrhosis and oesophageal varices with no history but at high risk of bleeding were randomized to ligation treatment (30 patients) or propranolol (30 patients)."5.11Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial. ( Elefsiniotis, I; Galanis, P; Goulas, S; Liatsos, C; Mavrogiannis, C; Papanikolaou, IS; Psilopoulos, D; Sparos, L, 2005)
" The aim of our study was to find out if propranolol can prevent the bleeding from esophageal varices and if it acts by reducing the portal inflow due to splanchnic vasodilatation."5.10Long term effects of propranolol on portal pressure in cirrhotic patients. ( Orban-Schiopu, AM; Popescu, CR, 2003)
"To compare the effectiveness of lanreotide SR, a new depot formulation injected once-weekly, and propranolol in reducing circadian portal blood flow (PVF) and meal-stimulated hepatic venous pressure gradient (HVPG) in patients with liver cirrhosis."5.10Effect of propranolol and depot lanreotide SR on postprandial and circadian portal haemodynamics in cirrhosis. ( Koch, L; Layer, G; Sauerbruch, T; Schiedermaier, P; Stoffel-Wagner, B, 2003)
"Propranolol ameliorates thrombocytopenia in patients with cirrhosis."5.10Propranolol ameliorates thrombocytopenia in patients with cirrhosis. ( Iwao, T; Oho, K; Sakai, K; Sata, M; Toyonaga, A, 2002)
"We compared propranolol therapy and endoscopic ligation for the primary prevention of bleeding from esophageal varices."5.09Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. ( Kumar, M; Lamba, GS; Misra, A; Murthy, NS; Sarin, SK, 1999)
"Thirty cirrhotic patients with PHT, grade III to IV oesophageal varices, hepatic venous pressure gradient > or = 12 mmHg and no prior history of upper gastrointestinal bleeding were randomized to receive propranolol (to reduce their pulse rate by 25% from baseline, n = 15) and EVL (weekly to fortnightly until variceal eradication, n = 15)."5.09Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial. ( Biswas, PK; Das, T; De, BK; Ghoshal, UC; Santra, A, 1999)
"To investigate the stereoselective metabolism of the propranolol enantiomers and its impact on portal haemodynamics in patients with liver cirrhosis since only S-propranolol is haemodynamically active."5.09Propranolol stereoisomer plasma concentrations and portal haemodynamic response in patients with liver cirrhosis. ( Brensing, K; Hoppe, A; Paar, D; Potyka, U; Raab, P; Sauerbruch, T; Schepke, M, 1999)
"Band ligation of esophageal varices may accentuate gastropathy, which in this study was partly relieved by propranolol."5.09The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial. ( Chen, TA; Cheng, JS; Chiang, HT; Hsu, PI; Lai, KH; Lin, CK; Lo, GH; Wang, EM, 2001)
"The absence of any effects on the parameters of portal haemodynamics would appear to deny clonidine any significant role in preventing first bleeding resulting from the rupture of oesophageal varices."5.08Effects of propranolol compared with clonidine on portal haemodynamics: a double-blind cross-over study using duplex-Doppler ultrasonography. ( Cioni, G; Cristani, A; D'Alimonte, P; Romagnoli, R; Tincani, E; Turrini, F; Ventura, E, 1995)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."5.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."5.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"This study tested the hypothesis that reduction in the hyperdynamic systemic circulation with propranolol in patients with alcoholic cirrhosis and distal splenorenal shunt would lead to improved maintenance of portal perfusion."5.07The effect of propranolol on portal perfusion in patients with alcoholic cirrhosis having distal splenorenal shunt. ( Galloway, JR; Gilmore, GT; Henderson, JM; Mackay, G, 1994)
"A prospective randomized double-blind study was conducted to evaluate the efficacy of propranolol in patients with portal hypertension undergoing long-term endoscopic sclerotherapy (EST) for recurrent variceal bleeding."5.07A prospective randomized study to evaluate propranolol in patients undergoing long-term endoscopic sclerotherapy. ( Acharya, SK; Dasarathy, S; Pande, JN; Saksena, S, 1993)
"Detailed examination of hemodynamics in patients with portal and pulmonary hypertension was performed upon acute drug tests and course administration of nitrosorbide++, corinfar and propranolol."5.07[Drug therapy of pulmonary and portal hypertension in liver cirrhosis]. ( Andreev, NG; Maev, IV; Vorob'ev, LP, 1991)
"To study the polymorphic markers CYP2D6*4 (G1846A, rs3892097), CYP2D6*6 (T1707del, rs5030655), CYP2D6*10 (C100T, rs1065852), CYP2D6*41 (G2988A, rs28371725) and CYP2D6*3 (A2549del, rs4986774) role in treatment optimization of portal hypertension with propranolol in patients with liver cirrhosis (LC)."4.12[CYP2D6 gene polymorphic markers role in determining the optimal treatment tactics for portal hypertension in patients with liver cirrhosis]. ( Akmalova, KA; Denisenko, NP; Loranskaya, ID; Parusov, AI; Sozaeva, ZA; Sychev, DA; Turkina, OL; Zastrozhin, MS, 2022)
"0 years, 34 boys) with CLD who needed liver biopsy but could not be done due to hypersplenism-related thrombocytopenia (platelets <100,000/mm(3) and/or total leukocyte counts <4,000/mm(3) with splenomegaly) were recruited and given a 4-week trial of long-acting propranolol (1."3.81β-Blocker therapy ameliorates hypersplenism due to portal hypertension in children. ( Agarwal, J; Baijal, SS; Kumar, S; Poddar, U; Shava, U; Srivastava, A; Yachha, SK, 2015)
"The aim of this study was to describe the results of endoscopic secondary prophylaxis, alone or in combination with propranolol, used to prevent upper gastrointestinal bleeding (UGIB) in children and adolescents with esophageal varices."3.79Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices. ( Bittencourt, PF; Carvalho, SD; dos Santos, JM; Fagundes, ED; Ferreira, AP; Ferreira, AR; Ferreira, LS; Figueiredo Filho, PP; Magalhães, MC; Penna, FJ, 2013)
"Droxidopa might be an effective therapeutic agent for hemodynamic and renal alterations of liver cirrhosis and should be tested in cirrhosis patients."3.78Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats. ( Augustin, S; Brull, A; Coll, M; Esteban, R; Ezkurdia, N; Genescà, J; Guardia, J; Martell, M; Raurell, I; Rodriguez, S, 2012)
"The aim of this study was to investigate the effect of rectal ozone on portal vein oxygenation and the pharmacokinetic changes of propranolol in patients with liver cirrhosis."3.77The effect of rectal ozone on the portal vein oxygenation and pharmacokinetics of propranolol in liver cirrhosis (a preliminary human study). ( Fouad, EA; Kotb, HI; Zaky, S, 2011)
"Propranolol treatment has been used to prevent variceal bleeding; however, controlled trials of its effectiveness have produced conflicting results."3.76Drug therapy for portal hypertension. ( Rector, WG, 1986)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."3.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
" propranolol before initiating secondary prophylaxis for variceal bleeding is a useful tool in predicting the efficacy of non-selective beta-blockers."3.75Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension. ( Abraldes, JG; Berzigotti, A; Bosch, J; García-Pagán, JC; La Mura, V; Raffa, S; Retto, O, 2009)
"propranolol, has been shown to be effective in compensated patients with alcoholic cirrhosis."3.75[Pharmacological therapy of portal hypertension]. ( Miotti, T; Reichen, J, 1985)
"In this model, pretreatment with propranolol prevented the increase in portal venous inflow, which occurs following hemorrhage and volume restitution with Haemaccel."3.71Systemic and splanchnic hemodynamics following hemorrhage and volume restitution with Haemaccel in portal hypertensive rats: the effect of propranolol. ( Arish, A; Hilzenrat, N; Sikuler, E; Yaari, A, 2001)
"Propranolol can reduce portal hypertension, therefore is recommended in prevention of variceal bleeding in patients with liver cirrhosis."3.69[Per-rectal scintigraphy of the portal system with pertechnetate TC-99M: effect of propranolol on portosystemic collateral circulation in patients with cirrhosis. Part II]. ( Bołdys, H; Hartleb, M; Nowak, A; Nowak, S; Rudzki, K, 1994)
"This study evaluates systemic and splanchnic haemodynamics and the effect of propranolol in 15 patients with presinusoidal portal hypertension (portal vein obstruction, n = 11; schistosomiasis, n = 4)."3.67Hyperkinetic circulatory syndrome in patients with presinusoidal portal hypertension. Effect of propranolol. ( Braillon, A; Hadengue, A; Lebrec, D; Moreau, R; Roulot, D; Sayegh, R, 1989)
" Seven patients with alcoholic cirrhosis received verapamil, 10 mg i."3.67Combination of ketanserin and verapamil or propranolol in patients with alcoholic cirrhosis: search for an additive effect. ( Cerini, R; Hadengue, A; Koshy, A; Lebrec, D; Lee, SS; Moreau, R, 1989)
"The effect of long-term propranolol administration on esophageal varices, portocollateral shunting, portal pressure, hepatosplanchnic hemodynamics, and liver function was studied in a pig model with experimentally induced prehepatic portal hypertension and esophageal varices."3.67Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices. ( Jensen, LS; Juhl, CO; Krarup, N; Larsen, JA; Nielsen, TH, 1989)
"To elucidate the mechanism by which propranolol reportedly affects portal hemodynamics, we investigated the effect of propranolol on systemic and splanchnic hemodynamics in 15 patients with portal hypertension and esophageal varices by simultaneous catheterization of the portal vein and the right hepatic vein and measurement of portal venous flow using an ultrasound doppler system."3.67Effects of propranolol on portal hemodynamics in patients with chronic liver disease. ( Hatano, H; Koen, H; Nakayama, T; Nomura, F; Ohnishi, K; Saito, M; Sugita, S; Terabayashi, H; Tsukamoto, T; Wada, K, 1985)
"Propranolol (20 mg 4 times a day) was given to patients with liver cirrhosis or fatty infiltration of the liver."3.66Propranolol increases arterial ammonia in liver cirrhosis. ( Koorevaar, G; Silberbusch, J; van Buuren, HR; van der Velden, PC, 1982)
" The aim of this study was to evaluate the effects of 5-MTHF in combination with propranolol on HVPG and nitric oxide bioavailability markers in patients with cirrhosis and portal hypertension."3.305-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial. ( Andreone, P; Berzigotti, A; Bosch, J; Di Donato, R; Gitto, S; Renzulli, M; Roncarati, G; Schepis, F; Simoni, P; Villa, E; Vukotic, R, 2023)
"Carvedilol is a non-selective beta-blocker (NSBB) acting on hyperdynamic circulation/splanchnic vasodilation and on intrahepatic resistance."3.01Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension. ( La Mura, V; Reiberger, T; Turco, L; Vitale, G, 2023)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."2.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Carvedilol is a non-selective β-blocker with intrinsic anti-α(1)-adrenergic activity, potentially more effective than propranolol in reducing hepatic venous pressure gradient (HVPG)."2.77Carvedilol or propranolol in portal hypertension? A randomized comparison. ( Bendtsen, F; Feldager Hansen, E; Grønbæk, H; Hobolth, L; Møller, S; Roelsgaard, K, 2012)
"Primary end points were recurrence of variceal bleeding or death."2.75Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension. ( Agrawal, A; Gupta, N; Jha, SK; Kumar, A; Mishra, SR; Sarin, SK; Sharma, BC, 2010)
" Additionally, they randomly received either placebo (N = 15) or irbesartan (step-up dosage titration up to 300 mg/d, N = 17)."2.73Irbesartan plus low-dose propranolol versus low-dose propranolol alone in cirrhosis: a placebo-controlled, double-blind study. ( Flacke, S; Ghauri, M; Heller, J; Herold, T; Sauerbruch, T; Schepke, M; Stoffel-Wagner, B; Wiest, R, 2008)
"Propranolol is a widely used drug for prophylaxis of variceal bleeding in patients with cirrhosis, but not all patients show an adequate clinical response."2.72Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices. ( De-Madaria, E; Hernández, FT; Horga, JF; Irurzun, J; Palazón, JM; Pascual, S; Perez-Mateo, M; Such, J; Zapater, P, 2006)
"Carvedilol is a nonselective beta-blocker with alpha(1)-adrenergic blocking activity."2.71Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis. ( Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Yang, YY, 2004)
"Short-term carvedilol administration is more powerful than propranolol in decreasing hepatic venous pressure gradient (HVPG) in cirrhotic patients, but induces arterial hypotension that may prevent its long-term use in portal hypertensive patients."2.70Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis. ( Abraldes, JG; Albillos, A; Bañares, R; Bosch, J; De Diego, A; García-Pagán, JC; Lampreave, JL; Matilla, A; Moitinho, E; Piera, C, 2002)
"Carvedilol is a relatively safe, effective portal hypotensive agent, both acutely and over 7 days, but not superior to propranolol, at least in Indians."2.70Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics. ( Biswas, PK; Das, D; De, BK; Maity, AK; Majumdar, D; Mandal, SK; Sen, S, 2002)
"Propranolol plus prazosin has a greater portal pressure-lowering effect than propranolol plus ISMN."2.69Propranolol plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension. ( Albillos, A; Bandi, JC; Bosch, J; Cacho, G; Calleja, JL; Escartín, P; Escorsell, A; García-Pagán, JC; Iborra, J; Pérez-Paramo, M, 1998)
"Propranolol was well tolerated with minimal side effects in our patients with portal hypertension."2.69Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study. ( Grand, RJ; Langhans, N; Shashidhar, H, 1999)
"Tertatolol was rapidly absorbed with a Cmax of 70 +/- 51 micrograms/l at a peak time of 0."2.67Hemodynamic and pharmacokinetic study of tertatolol in patients with alcoholic cirrhosis and portal hypertension. ( Brouard, R; Caillau, H; Calès, P; Crambes, O; Desmorat, H; Jung, L; Pascal, JP; Rocher, I; Urien, S; Vinel, JP, 1993)
"Eighteen cirrhotic patients with esophageal varices at risk for bleeding took part in a double-blind study."2.67Duplex Doppler ultrasonographic comparison of the effects of propranolol and isosorbide-5-mononitrate on portal hemodynamics. ( Abbati, G; Cioni, G; Cristani, A; D'Alimonte, P; Romagnoli, R; Tincani, E; Ventura, E; Ventura, P; Vignoli, A, 1993)
"When molsidomine was added, TAV was further decreased (-17."2.67[Evaluation of the effects of molsidomine and propranolol-molsidomine combination on portal hemodynamics by pulsed Doppler ultrasound]. ( Blanc, F; Bruel, JM; Ciurana, AJ; Le Quellec, A; Michel, H; Monnin, JL; Pascal, JP; Taourel, P; Vinel, JP, 1992)
"Propranolol-treated patients had fewer episodes of acute bleeding than controls (0."2.67Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis. ( Bosch, J; González, A; Panés, J; Pérez, R; Pérez-Ayuso, RM; Piqué, JM; Quintero, E; Rigau, J; Valderrama, R; Viver, J, 1991)
" Daily dosage was determined by the administration of progressively increasing doses of propranolol with the hepatic vein catheter in place to achieve a 25% decrease in hepatic venous pressure gradient, a decrease in hepatic venous pressure gradient to less than 12 mm Hg or a decrease in resting heart rate to less than 55 beats/min."2.67Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. The Boston-New Haven-Barcelona Portal Hypertension Study Group. ( Bosch, J; Conn, HO; Fisher, RL; Garcia-Tsao, G; Grace, ND; Groszmann, RJ; Matloff, DS; Navasa, M; Rodés, J; Wright, SC, 1991)
"No significant changes in the size of esophageal varices were observed after propranolol or placebo administration."2.67Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension. ( Bordas, JM; Bosch, J; Feu, F; Garcia-Pagán, JC; Rodés, J, 1991)
" The Cmax was significantly higher with C propranolol in both phases."2.66Pharmacodynamic and pharmacokinetic study of propranolol in patients with cirrhosis and portal hypertension. ( Blanc, M; Calès, P; Cotonat, J; Grasset, D; Meskens, C; Pascal, JP; Ravaud, A; Vinel, JP, 1989)
"Propranolol is a useful medicament for the reduction of esophagic varices size and prevention of digestive bleeding in cirrhotic patients."2.66[Propranolol in the prevention of digestive bleeding in cirrhotic patients]. ( Castro, R; Glez Cansino, J; Sotto, A, 1989)
"When propranolol was administered to patients with alcoholic cirrhosis and marginal liver function, as reflected by ammonia levels above 60 microM, it caused a significant increase in ammonia levels in arterialized-venous and arterial, but not in venous, blood (p less than 0."2.66Venous, arterial, and arterialized-venous blood ammonia levels and their relationship to hepatic encephalopathy after propranolol. ( Lieber, CS; Snady, H, 1988)
"Recent advances in the pharmacologic treatment of portal hypertension have mainly focused on modifying an increased intrahepatic resistance through nitric oxide and/or modulation of vasoactive substances."2.61Pharmacologic Management of Portal Hypertension. ( Bunchorntavakul, C; Reddy, KR, 2019)
"Carvedilol is a nonselective beta-blocker with a mild anti-alfa-1-adrenergic activity."2.50Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis. ( D'Amico, G; D'Amico, M; Perricone, G; Sinagra, E; Tinè, F, 2014)
"Carvedilol is a potent noncardioselective beta-blocker, with weak vasodilating properties because of alpha 1 blockade."2.46The role of carvedilol in the management of portal hypertension. ( Hayes, PC; Tripathi, D, 2010)
"Carvedilol appears to be a potentially viable option for treating portal hypertension."2.42Evaluation of carvedilol for the treatment of portal hypertension. ( Hemstreet, BA, 2004)
"Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin."2.41The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000)
"Hemorrhage from esophageal varices is a life-threatening event in patients with liver cirrhosis."2.39Beta-blockers for prophylaxis of bleeding from esophageal varices in cirrhotic portal hypertension. Review of the literature. ( Gross, M; Zoller, WG, 1996)
"Spironolactone, which has been shown to lower HVPG in patients with cirrhosis, produces a reduction in plasma volume that attenuates the increased cardiac output associated with cirrhosis and triggers vasoactive mechanisms that decrease splanchnic blood flow."2.38New approaches in the pharmacologic treatment of portal hypertension. ( Bosch, J; Fernández, M; Feu, F; García-Pagán, JC; Luca, A; Pizcueta, P; Rodés, J, 1993)
"The best results obtained in treatment of portal hypertension were: esophagogastric devascularization and splenectomy (EGDS), although risk of rebleeding persists; classical (proximal) splenorenal shunt (SRS) should be abandoned; distal splenorenal shunt may complicate with hepatic encephalopathy, although later and in a lower percentage than in SRS."2.38Portal hypertension in schistosomiasis: pathophysiology and treatment. ( Da Silva, LC, 1992)
"Although pharmacologic treatment of portal hypertension is known to be efficient, there are advances still to be made."2.38Current status and future goals of the pharmacologic reduction of portal hypertension. ( Lebrec, D, 1990)
"Only about one third of patients with esophageal varices eventually bleed."2.38[Treatment of hemorrhage of esophageal varices]. ( Sauerbruch, T, 1990)
"The development of bleeding esophagogastric varices and the methods used to treat this complication are all unsatisfactory either in the short or long term."2.37Theoretical and practical considerations in the treatment of portal hypertension secondary to hepatic cirrhosis. ( Bizer, LS, 1984)
"Bleeding from esophageal varices remains a difficult clinical problem, carrying a high likelihood both of rebleeding and of mortality."2.37Management of the patient with hemorrhaging esophageal varices. ( Cello, JP; Crass, RA; Grendell, JH; Trunkey, DD, 1986)
"Peptic ulcer disease, oesophageal varices and Mallory-Weiss tear are the major causes."2.36Management of upper gastrointestinal haemorrhage. ( Korman, MG, 1983)
"Her pregnancy was uneventful until 31 weeks gestation when she presented with dyspnoea."1.48Pregnancy in a patient with portal hypertension secondary to liver cirrhosis. ( Lelei-Mailu, FJ; Mariara, CM, 2018)
"Propranolol is a non-selective β-blocker that is recommended for the treatment of PH."1.42Comparative portal hypotensive effects as propranolol of vitamin D₃ treatment by decreasing intrahepatic resistance in cirrhotic rats. ( Hsieh, YC; Lee, KC; Lee, PC; Lee, TY; Lee, WP; Lin, HC; Yang, YY, 2015)
"Propranolol was associated with reduction in bleeding episodes (P < 0."1.42Extrahepatic portal vein obstruction in Egyptian children. ( El-Karaksy, HM; El-Koofy, N; El-Shabrawi, M; Helmy, H; Mohsen, N; Nabil, N, 2015)
"Metformin-treated CCl4-cirrhotic rats had lower PP and hepatic vascular resistance than vehicle-treated rats, without significant changes in MAP or PBF."1.42Metformin reduces hepatic resistance and portal pressure in cirrhotic rats. ( Bosch, J; Erice, E; García-Calderó, H; García-Pagán, JC; Gracia-Sancho, J; Lafoz, E; Sarin, SK; Tripathi, DM, 2015)
"Cirrhosis recurrence is frequent after orthotopic liver transplantation for hepatitis C virus (HCV)."1.39Hemodynamic response to propranolol in patients with recurrent hepatitis C virus-related cirrhosis after liver transplantation: a case-control study. ( Abraldes, JG; Berzigotti, A; Bosch, J; Carrión, JA; Forns, X; García-Pagán, JC; García-Valdecasas, JC; Navasa, M; Schepis, F; Vukotic, R, 2013)
"Berardinelli- Seip syndrome is an autosomal recessive disorder characterized by generalized lipoatrophy, extreme insulin resistance with dyslipidemia in childhood and development of diabetes in adolescence."1.38An unusual cause of delayed puberty: Berardinelli- Seip syndrome. ( Dhull, P; Kumar, KV; Patnaik, SK; Upreti, V, 2012)
"Portal hypertension was induced by PVL (portal vein ligation) in Sprague-Dawley rats."1.37Propranolol modulates the collateral vascular responsiveness to vasopressin via a G(α)-mediated pathway in portal hypertensive rats. ( Chang, CC; Chuang, CL; Huang, HC; Huo, TI; Lee, FY; Lee, JY; Lee, SD; Lin, HC; Wang, SS, 2011)
"Propranolol treatment reduces MAP significantly in hypertensive patients with cirrhosis."1.36The haemodynamic response to propranolol in cirrhosis with arterial hypertension: a comparative analysis with normotensive cirrhotic patients. ( Jha, S; Kumar, A; Mishra, SR; Sarin, SK; Sharma, BC; Sharma, P, 2010)
"Portal hypertension is a hemodynamic syndrome due to pathological increase in portal flow and portal pressure."1.35Combined use of propranolol and nifedipine offers better effects on portal vein nonuniform remodeling in carbon tetrachloride (CCl(4))-induced portal hypertensive rats. ( Jiang, ZL; Qin, KR; Shi, B; Wu, GQ; Zhang, ZQ; Zhu, L, 2009)
"All of them had high-risk esophageal varices at endoscopy."1.35Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension. ( Bittencourt, PL; Carrilho, FJ; da Rocha, EC; Dos Santos Bomfim, V; Farias, AQ; Kassab, F; Vezozzo, DC, 2009)
"Successful pharmacological treatment of portal hypertension can prevent the risk of the variceal bleeding, and contribute to reduce the morbidity and mortality in patients with liver cirrhosis."1.33[Pharmacological therapy of portal hypertension--focused on Korean data]. ( Baik, SK, 2005)
"Such varices are often the source of difficult-to-treat recurrent or chronic bleeding."1.33Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents? ( Detry, RJ; Douala, HC; Druez, PM; Geubel, AP; Kartheuser, AH; Kartheuzer, AH; Noubibou, M, 2006)
"The variceal recurrence rate was 65 and 38."1.32Long-term outcome after sclerotherapy with or without a beta-blocker for variceal bleeding in children. ( Elkabes, B; Saner, G; Sökücü, S; Süoglu, OD, 2003)
"Ectopic intestinal varices are rarely responsible for lower gastrointestinal (GI) haemorrhage."1.32Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage. ( Ahmed, I; Alam, A; Alvi, A; Butt, AK; Khan, AA; Niazi, A; Sarwar, S; Shafqat, F; Tarique, S, 2003)
"Larger gastric varices have been shown to be the only risk factor for rebleeding (adjusted odds ratio, 4."1.31Pharmacologic efficacy in gastric variceal rebleeding and survival: including multivariate analysis. ( Chen, GH; Wu, CY; Yeh, HZ, 2002)
"Propranolol or atenolol was administered by gavage in portal vein-stenosed and sham-operated rats."1.31Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension. ( Chagneau, C; Heller, J; Lebrec, D; Moreau, R; Pateron, D; Philippe, M; Poirel, O; Sogni, P; Tazi, KA, 2000)
" It was decided that patients whose portal pressure was reduced by 30% with the use of the drug would not undergo surgery and that treatment would consist of the chronic use of propranolol, associated with sclerosis of esophageal varices."1.30Systemic and hepatic hemodynamics in hepatosplenic Manson's schistosomiasis with and without propranolol. ( Alfieri, F; Baía, CE; Beer, A; Mies, S; Neto, OB; Pereira, LM; Raia, S; Sette, MJ, 1997)
" Our aim was to study the hemodynamic effects of the early and chronic administration of PR and spironolactone (SPN), alone or in combination, in a model of hepatic fibrosis and sinusoidal portal hypertension induced in rats by bile duct ligation."1.30Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation. ( Calès, P; Douay, O; Gallois, Y; Le Jeune, JJ; Maïga, MY; Oberti, F; Pilette, C; Rifflet, H; Saumet, JL, 1997)
" The present study aimed to investigate whether chronic administration of propranolol could improve vascular responsiveness in portal hypertensive rats."1.30Chronic administration of propranolol improves vascular contractile responsiveness in portal hypertensive rats. ( Hong, CY; Hou, MC; Huang, YT; Lin, HC; Tsai, JF, 1997)
"Portal hypertension was induced by partial portal vein ligation in Sprague-Dawley rats."1.30Hemodynamic effects of chronic tetrandrine and propranolol administration on portal hypertensive rats. ( Hong, CY; Huang, YT; Lin, HC; Liu, TB; Yang, MC, 1997)
"Propranolol or saline was administered by gavage, octreotide by subcutaneous injection."1.30Hemodynamic effects of eight-day octreotide and propranolol administration in portal hypertensive rats. ( Cheng, YR; Hong, CY; Hou, MC; Huang, YT; Lee, SD; Lin, HC, 1998)
"Portal hypertension was induced by partial portal vein ligation (PVL)."1.30Increased angiogenesis in portal hypertensive rats: role of nitric oxide. ( Battegay, E; Sieber, CC; Stumm, M; Sumanovski, LT; van der Kooij, M, 1999)
"The true form of portal hypertension is considered to be congestive gastropathy from the points that PHG is observed in high frequencies in the high portal pressure group, the severe esophageal varices group and group without gastrorenal or splenorenal shunt, that the mucosal blood flow rate in the lesion increased and that venectasia is present in the submucosal layer."1.29[Study of gastric mucosal lesion in portal hypertension]. ( Maruyama, T, 1995)
"Propranolol was administered orally to reduce portal hypertension, resulting in a progressive decrease in urinary microalbumin excretion."1.29IgA nephropathy associated with portal hypertension in liver cirrhosis due to non-alcoholic and non-A, non-B, non-C hepatitis. ( Aosaki, N; Hamaguchi, K; Iigaya, T; Kaneko, K; Miyoshi, Y; Monma, T; Nakamura, M; Ohishi, A; Sugiura, H; Watanabe, R, 1994)
" Thus, the hemodynamic effects of nipradilol, a new beta-adrenergic antagonist combined with a nitroxy base, was studied in conscious and unrestrained rats in two models of portal hypertension."1.29Hemodynamic effects of nipradilol, a new beta-adrenergic antagonist combined with a nitroxy base, in rats with intra- or extra-hepatic portal hypertension. ( Cailmail, S; Lebrec, D; Ohsuga, M, 1993)
"Portal hypertension is due to cirrhosis in 10 cases and to metastases to the liver in 4 cases."1.28[Colostomy-induced varices in portal hypertension]. ( Damamme, B; Poilleux, J, 1992)
" Nipradilol, at the dosage used in the present study, did not appear to exert a nitrovasodilating effect to enhance the portal pressure reduction induced by beta-blocking action."1.28Long-term haemodynamic effects of a 4-week regimen of nipradilol, a new beta-blocker with nitrovasodilating properties, in patients with portal hypertension due to cirrhosis. A comparative study with propranolol. ( Aramaki, T; Katsuta, Y; Komeichi, H; Kurokawa, H; Ohsuga, M; Okumura, H; Satomura, K; Sekiyama, T; Terada, H; Tsutsui, H, 1992)
"We investigated the effects of early chronic administration of propranolol on systemic and splanchnic hemodynamic changes, and the development of portal-systemic shunts in conscious, unrestrained, portal vein stenosed rats."1.28Early chronic administration of propranolol reduces the severity of portal hypertension and portal-systemic shunts in conscious portal vein stenosed rats. ( Cailmail, S; Lebrec, D; Lin, HC; Soubrane, O, 1991)
"The results of esophageal varices treatment in two groups of patients are shown."1.28[Sclerosing treatment of esophageal varices]. ( Jorge, AD; Milutin, C; Oliver, J, 1991)
"Propranolol was administered in drinking water to 20 animals for a period of 6 wk at a dose of 10 mg."1.28Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension. ( Bhatnagar, R; Dayal, Y; Groszmann, RJ; Mosca, PG; Reuben, A; Rojkind, M; Sarin, SK; Stadecker, MJ, 1991)
"Propranolol has been used to reduce cardiac output and portal pressure in these patients."1.28Effects of propranolol on arterial oxygenation and oxygen transport to tissues in patients with cirrhosis. ( Agusti, AG; Bosch, J; Garcia-Pagan, JC; Roca, J; Rodriguez-Roisin, R; Wagner, PD, 1990)
"Rats with chronic portal hypertension have an increased gastric mucosal blood flow and an impaired acid secretory response to pentagastrin stimulation."1.28Effects of propranolol on gastric microcirculation and acid secretion in portal hypertensive rats. ( Bosch, J; Pérez Ayuso, RM; Piqué, JM; Pizcueta, P, 1990)
"Since the gastritis is related to vascular changes and congestion of the stomach wall secondary to increased portal pressure, and not inflammation, measures aimed at local healing or surgical removal of the bleeding area fail."1.27Persistent hemorrhagic gastritis in a patient with portal hypertension and esophagogastric varices: the role of portal decompressive surgery. ( Babb, RR; Mitchell, RL, 1988)
"Sclerotherapy of esophageal varices consists in obstruction of the varicosities."1.27[Prevention of recurrent hemorrhage due to portal hypertension]. ( Lebrec, D, 1986)
" Increased dosage of propranolol to 4 mg did not produce any further reduction of portal pressure or mucosal damage."1.27Propranolol reduces ethanol-induced gastric mucosal damage in portal hypertensive rats. ( Ivey, KJ; Maeda, R; Mason, GR; Sankary, H; Sarfeh, IJ; Tarnawski, A, 1986)
"Bleeding from ileal varices can be managed by either local control or portal vein decompression."1.27Variceal bleeding from an ileostomy stoma. ( Dunn, GD; McGrew, W; Wang, MM, 1985)

Research

Studies (328)

TimeframeStudies, this research(%)All Research%
pre-199086 (26.22)18.7374
1990's107 (32.62)18.2507
2000's65 (19.82)29.6817
2010's63 (19.21)24.3611
2020's7 (2.13)2.80

Authors

AuthorsStudies
Sychev, DA1
Parusov, AI1
Loranskaya, ID1
Denisenko, NP1
Akmalova, KA1
Sozaeva, ZA1
Turkina, OL1
Zastrozhin, MS1
Turco, L1
Reiberger, T3
Vitale, G1
La Mura, V3
Danielsen, KV1
Nabilou, P1
Wiese, SS1
Hove, JD1
Bendtsen, F6
Møller, S7
Vukotic, R2
Di Donato, R1
Roncarati, G1
Simoni, P1
Renzulli, M1
Gitto, S1
Schepis, F2
Villa, E1
Berzigotti, A5
Bosch, J36
Andreone, P1
Bunchorntavakul, C1
Reddy, KR1
Shao, R1
Li, Z1
Wang, J1
Qi, R1
Liu, Q1
Zhang, W1
Mao, X1
Song, X1
Li, L1
Liu, Y1
Zhao, X1
Liu, C1
Li, X1
Zuo, C1
Wang, W1
Qi, X1
Afaa, TJ1
Amegan-Aho, KH1
Richardson, E1
Goka, B1
Lim, YL1
Kim, MY6
Jang, YO1
Baik, SK6
Kwon, SO4
McDonald, N1
Lilburn, DML1
Lachlan, NJ1
Macnaught, G1
Patel, D1
Jayaswal, ANA1
Hayes, PC6
Semple, SI1
Fallowfield, JA1
Grammatikopoulos, T1
McKiernan, PJ1
Dhawan, A1
Püspök, A1
Schoder, M1
Baumann-Durchschein, F1
Bucsics, T1
Datz, C1
Dolak, W1
Ferlitsch, A2
Finkenstedt, A1
Graziadei, I1
Hametner, S1
Karnel, F1
Krones, E1
Maieron, A1
Mandorfer, M1
Peck-Radosavljevic, M2
Rainer, F1
Schwabl, P1
Stadlbauer, V1
Stauber, R1
Tilg, H1
Trauner, M1
Zoller, H1
Schöfl, R1
Fickert, P1
Bishnu, S1
Ahammed, SM1
Sarkar, A1
Hembram, J1
Chatterjee, S1
Das, K2
Dhali, GK1
Chowdhury, A1
Baiges, A2
Hernández-Gea, V3
Lelei-Mailu, FJ1
Mariara, CM1
Abd Alla, MD1
Eid, EMM1
Soliman, AIA1
Elhawary, MA1
Kilany, YF1
Abd-Almonaem, G1
Bayoumi, SS1
Moursy, MRA1
Al-Zaem, FAM1
de Araújo, LJT1
Nagaoka, MR1
Borges, DR1
Kouyoumdjian, M1
Li, LN1
Sun, XY1
Wang, GC1
Tian, XG1
Zhang, MY1
Jiang, KT1
Zhang, CQ1
Reverter, E2
Lozano, JJ1
Alonso, C1
Seijo, S2
Turon, F1
Martínez-Chantar, ML1
Mato, JM1
Martínez-Arranz, I1
García-Pagán, JC26
Kim, BH1
Chung, JW1
Lee, CS1
Jang, ES1
Jeong, SH1
Kim, N1
Kim, JW2
Villanueva, C3
Albillos, A8
Genescà, J3
Calleja, JL3
Aracil, C3
Bañares, R7
Morillas, RM2
Poca, M2
Peñas, B2
Augustin, S3
Abraldes, JG11
Alvarado, E1
Torres, F1
Zaghloul, SG1
Wahab, EA1
Seleem, WM1
Hanafy, AS1
Gomaa, AF1
Lakouz, K1
Amin, AI1
Carrión, JA1
Forns, X1
García-Valdecasas, JC1
Navasa, M4
Kong, DR3
Zhang, C1
Zhang, L2
Wang, JG3
Xiong, Z1
Li, P2
Xu, JM3
Upreti, V1
Dhull, P1
Patnaik, SK1
Kumar, KV1
Gupta, N2
Kumar, A4
Sharma, P3
Garg, V1
Sharma, BC4
Sarin, SK7
Heebøll, S1
Villadsen, GE1
Aagaard, NK1
Grønbæk, H2
Vilstrup, H1
Keiding, S1
Ma, C1
Wang, M1
Chen, C2
Hao, JH1
Hobolth, L3
Hansen, EF1
Sinagra, E1
Perricone, G1
D'Amico, M2
Tinè, F2
D'Amico, G3
Kimer, N1
Feineis, M1
Lee, PC1
Yang, YY2
Lee, WP1
Lee, KC1
Hsieh, YC1
Lee, TY1
Lin, HC8
Celtik, C1
Durmaz, O1
Oner, N1
Yavuz, T1
Gökce, S1
Aydogan, A1
Nisli, K1
Emiroglu, HH1
Ömeroglu, RE1
Sökücü, S2
El-Karaksy, HM1
El-Koofy, N1
Mohsen, N1
Helmy, H1
Nabil, N1
El-Shabrawi, M2
Kim, JH1
Kim, JM1
Cho, YZ1
Na, JH1
Kim, HS3
Kim, HA1
Kang, HW1
Cha, SH1
Kim, YJ3
Poddar, U1
Shava, U1
Yachha, SK1
Agarwal, J1
Kumar, S1
Baijal, SS1
Srivastava, A1
Iwakiri, Y1
Sun, B1
Wang, MQ1
Yu, FF1
Tripathi, DM1
Erice, E2
Lafoz, E1
García-Calderó, H1
Gracia-Sancho, J1
Morillas, R1
Pavel, O1
Wang, D1
Wang, Q2
Yin, J1
Dong, R1
Du, X1
Lu, J1
Kalambokis, GN1
Baltayiannis, G1
Christou, L1
Christodoulou, D1
Brito-Azevedo, A2
Perez, Rde M1
Coelho, HS2
Fernandes, Ede S1
Castiglione, RC2
Villela-Nogueira, CA2
Bouskela, E2
Li, T1
Ke, W1
Sun, P1
Chen, X1
Belgaumkar, A1
Huang, Y1
Xian, W1
Li, J1
Zheng, Q1
Perez, RM1
Fernandes, ES1
Kim, SG1
Kim, TY1
Sohn, JH1
Um, SH1
Seo, YS1
Jang, JY1
Jeong, SW1
Lee, B1
Kim, YS1
Suk, KT1
Kim, DJ1
Steib, CJ1
Gerbes, AL1
Alatsakis, M2
Ballas, KD1
Pavlidis, TE1
Psarras, K2
Rafailidis, S2
Tzioufa-Asimakopoulou, V2
Marakis, GN1
Sakantamis, AK1
Lebrec, L1
Colomo, A1
López-Balaguer, JM1
Alvarez-Urturi, C1
Torras, X1
Balanzó, J1
Guarner, C1
Zhang, ZQ1
Shi, B1
Wu, GQ1
Qin, KR1
Jiang, ZL1
Zhu, L1
Jha, SK2
Dubey, S1
Tyagi, P1
Raffa, S1
Retto, O1
Farias, AQ1
Kassab, F1
da Rocha, EC1
Dos Santos Bomfim, V1
Vezozzo, DC1
Bittencourt, PL1
Carrilho, FJ1
Demertzidis, C1
Ballas, K1
Symeonidis, N1
Pavlidis, T1
Sakadamis, A1
Trebicka, J1
Hennenberg, M1
Schulze Pröbsting, A1
Laleman, W2
Klein, S1
Granzow, M1
Nevens, F4
Zaagsma, J1
Heller, J3
Sauerbruch, T8
Tripathi, D1
Jha, S1
Mishra, SR2
Kaltoft, N1
Agrawal, A1
Thevenot, T2
Cervoni, JP2
Monnet, E1
Sheppard, F1
Martino, VD1
Pastore, S1
Londero, M1
Cont, G1
Di Leo, G1
Ventura, A1
Juraschek, SP1
Bankova, L1
Falade, O1
Chow, G1
McKenzie, R1
Bhogal, HK1
Di Martino, V1
Zaky, S1
Fouad, EA1
Kotb, HI1
Angeli, P1
Bocci, V1
Zanardi, I1
Travagli, V1
Lee, JY1
Huo, TI1
Huang, HC2
Lee, FY3
Chuang, CL1
Chang, CC2
Wang, SS2
Lee, SD5
Catalina, MV1
Ripoll, C1
Rincón, D1
Hassanin, F1
Payer, BA1
Pinter, M1
Homoncik, M1
Roelsgaard, K1
Feldager Hansen, E1
Mejías, M1
García-Pras, E1
Fernández, M3
Llop, E1
Conget, I1
Grimaldi, C1
de Ville de Goyet, J1
Nobili, V1
Coll, M1
Rodriguez, S1
Raurell, I1
Ezkurdia, N1
Brull, A1
Guardia, J1
Esteban, R1
Martell, M1
dos Santos, JM1
Ferreira, AR1
Fagundes, ED1
Ferreira, AP1
Ferreira, LS1
Magalhães, MC1
Bittencourt, PF1
Carvalho, SD1
Figueiredo Filho, PP1
Penna, FJ1
Agasti, AK1
Mahajan, AU1
Phadke, AY1
Nathani, PJ1
Sawant, P1
Reboredo, M1
Chang, HC1
Barbero, R1
Rodríguez-Ortigosa, CM1
Pérez-Vizcaíno, F1
Morán, A1
García, M1
Banales, JM1
Carreño, N1
Alegre, F1
Herrero, I1
Quiroga, J1
Prieto, J1
Sangro, B1
Wu, CY1
Yeh, HZ1
Chen, GH1
Brensing, KA1
Hörsch, M1
Textor, J1
Schiedermaier, P2
Raab, P2
Schepke, M4
Strunk, H1
Schild, H1
Bureau, C1
Péron, JM1
Alric, L1
Morales, J1
Sanchez, J1
Barange, K2
Payen, JL3
Vinel, JP5
Moitinho, E6
Matilla, A1
Lampreave, JL1
Piera, C2
De Diego, A2
Bellis, L1
Graupera, M1
Rodés, J13
Liang, YG1
Chu, XJ1
Venon, WD1
Baronio, M1
Leone, N1
Rolfo, E1
Fadda, M1
Barletti, C1
Todros, L1
Saracco, G1
Rizzetto, M1
Tarantino, I1
Turnes, J2
Orban-Schiopu, AM1
Popescu, CR1
Blendis, L2
Lurie, Y1
Oren, R1
Blendis, LM2
Wong, F2
De, BK3
Bandyopadhyay, K1
Das, TK1
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Majumdar, D2
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Ray, S1
Dasgupta, S1
Süoglu, OD1
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Butt, AK1
Shafqat, F1
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Ahmed, I1
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Stoffel-Wagner, B2
Layer, G1
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Choi, YJ1
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Hou, MC3
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Tadzhiev, IIa1
Sergienko, VB1
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Jutabha, R1
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Orban Schiopu, AM1
Balas, BI1
Diculescu, M1
Psilopoulos, D1
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Goulas, S1
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Elefsiniotis, I1
Liatsos, C1
Sparos, L1
Mavrogiannis, C1
Chan, CC1
Chang, FY1
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Lim, DW1
Lee, SS5
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Russell, RI1
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Gimson, AE1
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Chadda, S1
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Clinical Trials (17)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)[NCT03783065]40 participants (Anticipated)Interventional2019-01-02Recruiting
A Prospective Multicenter Cohort Study on the Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in Cirrhosis[NCT04932200]608 participants (Anticipated)Observational2021-06-15Not yet recruiting
Timing of Endoscopic Intervention in Patients With Cirrhosis With Acute Variceal Upper Gastrointestinal Hemorrhage (TEACH Trial): a Randomized Clinical Trial[NCT04786743]400 participants (Anticipated)Interventional2021-04-20Recruiting
A Novel Algorithm to Stratify Clinical Decompensation Risk in Patients With Compensated Advanced Chronic Liver Disease (CHESS2108)[NCT05100485]1,000 participants (Actual)Observational2022-01-01Completed
Multicenter, Randomized, Double-blind, Placebo-controlled Study on the Effectiveness of Treatment With Beta-blockers to Prevent Decompensation of Cirrhosis With Portal Hypertension[NCT01059396]Phase 4201 participants (Actual)Interventional2010-01-28Completed
CHESS-SAVE Score to Stratify Decompensation Risk in Compensated Advanced Chronic Liver Disease: an International Multicenter Study (CHESS2102)[NCT04975477]1,000 participants (Anticipated)Observational2021-07-16Not yet recruiting
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis: a Prospective Cohort Study[NCT04543643]Phase 3288 participants (Anticipated)Interventional2021-11-01Not yet recruiting
Prevention of Progression of Portal Hypertension in Compensated Cirrhosis Using Selective Hepatic Vasodilators. A Double-blind, Multicenter,Randomized Controlled Trial[NCT01282398]Phase 480 participants (Anticipated)Interventional2011-04-30Not yet recruiting
Banding Ligation Plus Propranolol Versus Banding Ligation to Prevent Rebleeding of Esophageal Varices[NCT02740166]Phase 4212 participants (Anticipated)Interventional2013-06-30Recruiting
Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252]Phase 119 participants (Actual)Interventional2013-10-31Completed
Comparison of Endoscopic Variceal Ligation (EVL) and Propranolol in Secondary Prophylaxis of Variceal Bleeding in Patients With Non Cirrhotic Portal Hypertension (NCPH): A Prospective Randomized Controlled Trial[NCT01000779]Phase 3100 participants (Anticipated)Interventional2005-01-31Completed
Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline: A Placebo Controlled, Blinded Pilot Study[NCT02123576]12 participants (Actual)Interventional2014-04-30Terminated (stopped due to Poor enrollment of study population)
Prospective Cohort Study to Evaluate Long-term Outcomes in Patients With Liver Cirrhosis of Boramae Hospital[NCT01943318]500 participants (Actual)Observational [Patient Registry]2013-01-31Completed
Danish Carvedilol Study in Portal Hypertension. Carvedilol in the Prevention of Bleeding in Portal Hypertension and Esophageal Varices[NCT00493480]Phase 340 participants (Anticipated)Interventional2003-09-30Completed
Is Capsule Endoscopy Accurate and Cost-effective Enough to Screen Cirrhotic Patients for Varices & Other Lesions?[NCT01079416]65 participants (Actual)Observational2006-06-30Completed
Propanolol for Primary Prophylaxis for Variceal Bleed in Biliary Atresia - An Open Label Randomized Controlled Study[NCT04494763]92 participants (Anticipated)Interventional2020-08-15Recruiting
Randomized, Double-Blind Study of Timolol (A Nonselective Beta-Adrenergic Blocker) vs Placebo to Prevent Complications of Hepatic Portal Hypertension in Patients With Cirrhosis[NCT00006398]Phase 3213 participants (Actual)Interventional1993-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Serum Creatinine From Baseline

(NCT02123576)
Timeframe: baseline and 14 days

Interventiong/dL (Mean)
Treatment0.48
Placebo0.03

Incidence of Treatment Failure

Defined as creatinine level above baseline value after day 7, dialysis or death (NCT02123576)
Timeframe: up to day 14

InterventionParticipants (Count of Participants)
Treatment3
Placebo3

Number of Participants With Combined Outcome of Treatment Success and Partial Response

We define as serum creatinine level decreased by >50% from baseline but not to <1.5 mg/dL, without dialysis or HRS recurrence (NCT02123576)
Timeframe: 14 days

InterventionParticipants (Count of Participants)
Treatment1
Placebo2

Number of Participants With Treatment Success

We define this as a decrease in serum creatinine level to <1.5 mg/dL without dialysis or death (NCT02123576)
Timeframe: 14 days

InterventionParticipants (Count of Participants)
Treatment1
Placebo1

Overall Survival

This will be the combination of transplant free survival and those patients who received liver transplant (NCT02123576)
Timeframe: up to 1 year

Interventiondays (Mean)
Treatment102
Placebo59

Transplant Free Survival

(NCT02123576)
Timeframe: day 30 and 180

Interventiondays (Mean)
Treatment80
Placebo36

Reviews

48 reviews available for propranolol and Hypertension, Portal

ArticleYear
Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal H

2023
Pharmacologic Management of Portal Hypertension.
    Clinics in liver disease, 2019, Volume: 23, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anticoagulants; Antihypertensi

2019
Portal hypertension and its management in children.
    Archives of disease in childhood, 2018, Volume: 103, Issue:2

    Topics: Adrenergic beta-Antagonists; Child; Consensus; Endoscopy; Gastrointestinal Hemorrhage; Guidelines as

2018
Pharmacologic prevention of variceal bleeding and rebleeding.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; G

2018
Systematic review with meta-analysis: the haemodynamic effects of carvedilol compared with propranolol for portal hypertension in cirrhosis.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:6

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Hemodynamics; Hepatic Veins; Humans; Hypertensi

2014
Beta-blockers in cirrhosis and refractory ascites: a retrospective cohort study and review of the literature.
    Scandinavian journal of gastroenterology, 2015, Volume: 50, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Case-Control Studies; Esophageal and Gastric Varices; Fe

2015
Carvedilol for portal hypertension in cirrhosis: systematic review with meta-analysis.
    BMJ open, 2016, 05-04, Volume: 6, Issue:5

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Ga

2016
Beta-blockers in the prevention of gastrointestinal bleeding.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 1990, Volume: 42 Suppl

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Esophageal and Gastr

1990
The role of carvedilol in the management of portal hypertension.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:8

    Topics: Antihypertensive Agents; Ascites; Benzopyrans; Carbazoles; Carvedilol; Drug Therapy, Combination; Et

2010
Prognostic markers in patients who have recovered from an acute variceal bleeding: role of HVPG measurement.
    Disease markers, 2011, Volume: 31, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Biomarkers; Esophageal and Gastric Varices; Ga

2011
Propranolol safety profile in children.
    Current drug safety, 2011, Sep-01, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Age Factors; Angina Pectoris; Central Nervous System Diseases; Child; D

2011
Evaluation of carvedilol for the treatment of portal hypertension.
    Pharmacotherapy, 2004, Volume: 24, Issue:1

    Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Fibrosis; Humans; Hy

2004
Cirrhotic portal hypertension: current and future medical therapy for primary and secondary prevention of variceal bleeding.
    Minerva medica, 2006, Volume: 97, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Contraindications; Drug Therapy, Combination; Endoscopy; Esoph

2006
[The effect of propranolol on portal hypertension].
    Srpski arhiv za celokupno lekarstvo, 1992, Volume: 120 Suppl 4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

1992
[New therapeutic possibilities of propranolol].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:12

    Topics: Antithyroid Agents; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases;

1984
Medical treatment of portal hypertension and oesophageal varices.
    British medical journal (Clinical research ed.), 1983, Sep-10, Volume: 287, Issue:6394

    Topics: Blood Flow Velocity; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hem

1983
Management of upper gastrointestinal haemorrhage.
    Annals of the Academy of Medicine, Singapore, 1983, Volume: 12, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Embolization, Therapeutic; Esophageal and Gastric Varices; E

1983
Theoretical and practical considerations in the treatment of portal hypertension secondary to hepatic cirrhosis.
    The American surgeon, 1984, Volume: 50, Issue:10

    Topics: Animals; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal;

1984
[Portal hypertension: value of combination of nitrate derivatives and beta blockers for better prevention?].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:3

    Topics: Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate;

1995
New approaches in the pharmacologic treatment of portal hypertension.
    Journal of hepatology, 1993, Volume: 17 Suppl 2

    Topics: Adrenergic beta-Antagonists; Humans; Hypertension, Portal; Propranolol; Serotonin Antagonists; Spiro

1993
[Vasodilators and renal function in cirrhosis].
    Gastroenterologia y hepatologia, 1995, Volume: 18, Issue:9

    Topics: Drug Therapy, Combination; Humans; Hypertension, Portal; Kidney; Liver Cirrhosis; Propranolol; Vasod

1995
[Gastropathy due to portal hypertension].
    Praxis, 1997, Jan-21, Volume: 86, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diagnosis, Differential; Gastritis

1997
Beta-blockers for prophylaxis of bleeding from esophageal varices in cirrhotic portal hypertension. Review of the literature.
    European journal of medical research, 1996, Jun-25, Volume: 1, Issue:9

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointest

1996
Portal-hypertensive gastropathy.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:9

    Topics: Esophageal and Gastric Varices; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; H

1998
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination

2000
Pharmacologic therapy for portal hypertension.
    Current gastroenterology reports, 2001, Volume: 3, Issue:1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Endoscopy, Gastrointestinal; Gastrointestinal Agents; Ga

2001
Portal hypertension in schistosomiasis: pathophysiology and treatment.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Animals; Cricetinae; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage;

1992
Prevention of first variceal bleeding: new prospects.
    JPMA. The Journal of the Pakistan Medical Association, 1992, Volume: 42, Issue:2

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointesti

1992
Balloon tamponade and vasoactive drugs in the control of acute variceal haemorrhage.
    Bailliere's clinical gastroenterology, 1992, Volume: 6, Issue:3

    Topics: Antihypertensive Agents; Balloon Occlusion; Catheterization; Esophageal and Gastric Varices; Gastroi

1992
Portal hypertensive gastropathy.
    Bailliere's clinical gastroenterology, 1992, Volume: 6, Issue:3

    Topics: Animals; Diagnosis, Differential; Esophageal and Gastric Varices; Gastric Mucosa; Gastritis; Gastroi

1992
Propranolol in variceal hemorrhage.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:1

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1992
[Beta-adrenergic antagonists and endoscopic sclerotherapy for the prevention of digestive hemorrhage].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:11

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Endoscopy, Gastrointestinal; Gastrointestina

1991
Portal hypertensive gastropathy.
    Digestive diseases (Basel, Switzerland), 1991, Volume: 9, Issue:5

    Topics: Animals; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis;

1991
[Chemotherapy of portal hypertension].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:4

    Topics: Antihypertensive Agents; Drug Evaluation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhag

1991
Long-term pharmacologic therapy of portal hypertension.
    The Surgical clinics of North America, 1990, Volume: 70, Issue:2

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Hemodynamics; Humans; Hypertension, Portal; M

1990
Current status and future goals of the pharmacologic reduction of portal hypertension.
    American journal of surgery, 1990, Volume: 160, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Hemodynamics; Humans; Hypertension, Portal;

1990
Meta-analysis of value of propranolol in prevention of variceal haemorrhage.
    Lancet (London, England), 1990, Jul-21, Volume: 336, Issue:8708

    Topics: Adrenergic beta-Antagonists; Chi-Square Distribution; Drug Evaluation; Esophageal and Gastric Varice

1990
[Treatment of hemorrhage of esophageal varices].
    Leber, Magen, Darm, 1990, Volume: 20, Issue:1

    Topics: Balloon Occlusion; Catheterization; Combined Modality Therapy; Esophageal and Gastric Varices; Gastr

1990
New concepts of pathophysiology and treatment of portal hypertension.
    Surgery, 1990, Volume: 107, Issue:5

    Topics: Cardiology; Hemorrhage; Humans; Hypertension, Portal; Propranolol; Sclerotherapy; Varicose Veins; Va

1990
[Beta blockaders and portal hypertension].
    La Revue du praticien, 1989, Apr-27, Volume: 39, Issue:13

    Topics: Adrenergic beta-Antagonists; Animals; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertensio

1989
Safety of propranolol in portal hypertension. Conventional and long acting formulations.
    Drugs, 1989, Volume: 37 Suppl 2

    Topics: Delayed-Action Preparations; Humans; Hypertension, Portal; Propranolol

1989
[Pharmacological therapy of portal hypertension].
    Schweizerische medizinische Wochenschrift, 1985, Oct-19, Volume: 115, Issue:42

    Topics: Acute Disease; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Esophageal an

1985
Advances in managing variceal bleeding in portal hypertension.
    Surgery annual, 1986, Volume: 18

    Topics: Catheterization; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemorrh

1986
Drug therapy for portal hypertension.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Animals; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemo

1986
Pharmacological therapy of portal hypertension.
    Digestive diseases (Basel, Switzerland), 1986, Volume: 4, Issue:4

    Topics: Acute Disease; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hypertension,

1986
The medical prevention of variceal bleeding.
    Intensive care medicine, 1988, Volume: 14, Issue:2

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1988
Management of the patient with hemorrhaging esophageal varices.
    JAMA, 1986, Sep-19, Volume: 256, Issue:11

    Topics: Airway Obstruction; Catheterization; Esophageal and Gastric Varices; Fluid Therapy; Gastrointestinal

1986
Ideal treatment of portal hypertension in 1985.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Acute Disease; Clinical Trials as Topic; Double-Blind Method; Endoscopy; Esophageal and Gastric Vari

1985

Trials

102 trials available for propranolol and Hypertension, Portal

ArticleYear
5-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial.
    Journal of hepatology, 2023, Volume: 79, Issue:4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

2023
Hepatic venous pressure gradient-guided laparoscopic splenectomy and pericardial devascularisation versus endoscopic therapy for secondary prophylaxis for variceal rebleeding in portal hypertension (CHESS1803): study protocol of a multicenter randomised c
    BMJ open, 2020, 06-23, Volume: 10, Issue:6

    Topics: China; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Human

2020
Rifaximin and Propranolol Combination Therapy Is More Effective than Propranolol Monotherapy for the Reduction of Portal Pressure: An Open Randomized Controlled Pilot Study.
    Gut and liver, 2017, Sep-15, Volume: 11, Issue:5

    Topics: Adult; Antihypertensive Agents; Bacterial Translocation; Drug Therapy, Combination; Female; Gastroin

2017
Assessment of Haemodynamic Response to Nonselective Beta-Blockers in Portal Hypertension by Phase-Contrast Magnetic Resonance Angiography.
    BioMed research international, 2017, Volume: 2017

    Topics: Adrenergic beta-Antagonists; Aged; Aorta, Abdominal; Carbazoles; Carvedilol; Contrast Media; Female;

2017
Effects of atorvastatin on portal hemodynamics and clinical outcomes in patients with cirrhosis with portal hypertension: a proof-of-concept study.
    European journal of gastroenterology & hepatology, 2018, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atorvastatin; Disease Progression; Drug

2018
PORTAL HYPERTENSION TREATMENT WITH CANDESARTAN PLUS PROPRANOLOL FOR NINE MONTHS RESTORES NORMAL PORTAL CIRCULATION HEMODYNAMIC PATTERN.
    Journal of the Egyptian Society of Parasitology, 2016, Volume: 46, Issue:3

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Ther

2016
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial.
    Lancet (London, England), 2019, Apr-20, Volume: 393, Issue:10181

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Ascites; Carvedilol; Double-Blind Me

2019
Measurement of variceal pressure with a computerized endoscopic manometry: validation and effect of propranolol therapy in cirrhotic patients.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adult; Antihypertensive Agents; Esophageal and Gastric Varices; Esophagoscopes; Esophagoscopy; Femal

2013
Effects of the adjunctive probiotic VSL#3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:8

    Topics: Adult; Analysis of Variance; Anti-Bacterial Agents; Biomarkers; Chi-Square Distribution; Combined Mo

2013
Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis.
    World journal of gastroenterology, 2013, Jul-14, Volume: 19, Issue:26

    Topics: Adult; China; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal He

2013
Effects of carvedilol and propranolol on circulatory regulation and oxygenation in cirrhosis: a randomised study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2014, Volume: 46, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Arteries; Blood Pressure; Bloo

2014
Effects of candesartan and propranolol combination therapy versus propranolol monotherapy in reducing portal hypertension.
    Clinical and molecular hepatology, 2014, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure

2014
Development of hyperdynamic circulation and response to β-blockers in compensated cirrhosis with portal hypertension.
    Hepatology (Baltimore, Md.), 2016, Volume: 63, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Do

2016
A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:11

    Topics: Adult; Antihypertensive Agents; Ascites; Carbazoles; Carvedilol; End Stage Liver Disease; Esophageal

2016
Acute hemodynamic response to beta-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding.
    Gastroenterology, 2009, Volume: 137, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrha

2009
Addition of propranolol and isosorbide mononitrate to endoscopic variceal ligation does not reduce variceal rebleeding incidence.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Combined Modality Therapy; Endoscopy, Digestive System; Esophageal and Gastric Varices; Femal

2009
Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension.
    Gastroenterology, 2010, Volume: 139, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Child; Child, Preschool; Esophageal and Gastric Vari

2010
Carvedilol or propranolol in portal hypertension? A randomized comparison.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Double-Blind Method; Fema

2012
Comparative randomized study on efficacy of losartan versus propranolol in lowering portal pressure in decompensated chronic liver disease.
    Journal of digestive diseases, 2013, Volume: 14, Issue:5

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Female; Follow-Up Studies;

2013
Hemodynamic effects of propranolol and nitrates in cirrhotics with transjugular intrahepatic portosystemic stent-shunt.
    Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:9

    Topics: Blood Pressure; Drug Combinations; Female; Heart Rate; Hemodynamics; Humans; Hypertension, Portal; L

2002
"A La Carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:6

    Topics: Adult; Female; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Isosorbide Dinitrate; Male

2002
Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:6

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hyperten

2002
[Effect of compound Salvia pill combined with propanolol on liver fibrosis and portal hypertension].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2002, Volume: 22, Issue:5

    Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up

2002
Effects of long-term Irbesartan in reducing portal pressure in cirrhotic patients: comparison with propranolol in a randomised controlled study.
    Journal of hepatology, 2003, Volume: 38, Issue:4

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pr

2003
Long term effects of propranolol on portal pressure in cirrhotic patients.
    Romanian journal of gastroenterology, 2003, Volume: 12, Issue:1

    Topics: Antihypertensive Agents; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemody

2003
Portal pressure response to losartan compared with propranolol in patients with cirrhosis.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Esophageal and Gastric

2003
Effect of propranolol and depot lanreotide SR on postprandial and circadian portal haemodynamics in cirrhosis.
    Alimentary pharmacology & therapeutics, 2003, Oct-15, Volume: 18, Issue:8

    Topics: Antihypertensive Agents; Circadian Rhythm; Delayed-Action Preparations; Esophageal and Gastric Varic

2003
Captopril reduces portal pressure effectively in portal hypertensive patients with low portal venous velocity.
    Journal of gastroenterology, 2003, Volume: 38, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Flow Velocity; Captopril; D

2003
Acute administration of carvedilol is more effective than propranolol plus isosorbide-5-mononitrate in the reduction of portal pressure in patients with viral cirrhosis.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:10

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Drug Therapy, Combination; Female; Humans; Hyperten

2004
[Comparative effectiveness of different methods of diagnosis and correction of impaired portal circulation].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:7

    Topics: Antihypertensive Agents; Humans; Hypertension, Portal; Isosorbide Dinitrate; Laser Therapy; Liver Ci

2004
Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices.
    Gastroenterology, 2005, Volume: 128, Issue:4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu

2005
Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:10

    Topics: Adrenergic beta-Antagonists; Aged; Cause of Death; Epidemiologic Methods; Esophageal and Gastric Var

2005
Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices.
    Vascular pharmacology, 2006, Volume: 44, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alcohol Drinking; Cyclic A

2006
Damping index of Doppler hepatic vein waveform to assess the severity of portal hypertension and response to propranolol in liver cirrhosis: a prospective nonrandomized study.
    Liver international : official journal of the International Association for the Study of the Liver, 2007, Volume: 27, Issue:8

    Topics: Adult; Aged; Antihypertensive Agents; Female; Hepatic Veins; Humans; Hypertension, Portal; Linear Mo

2007
Irbesartan plus low-dose propranolol versus low-dose propranolol alone in cirrhosis: a placebo-controlled, double-blind study.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:5

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphe

2008
Propranolol--a medical treatment for portal hypertension?
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Administration, Oral; Cardiac Output; Clinical Trials as Topic; Esophageal and Gastric Varices; Gast

1980
Propranolol in portal hypertension.
    Lancet (London, England), 1981, May-30, Volume: 1, Issue:8231

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension, Portal; Male; Midd

1981
Propranolol in decompensated alcoholic cirrhosis.
    Lancet (London, England), 1982, Nov-06, Volume: 2, Issue:8306

    Topics: Heart; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Male; Propranolol; Risk

1982
Comparison of three adrenoreceptor blocking agents in patients with cirrhosis and portal hypertension.
    Gut, 1984, Volume: 25, Issue:1

    Topics: Atenolol; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; Humans; Hyperte

1984
Propranolol and haemorrhage due to rupture of oesophageal varices.
    Hepato-gastroenterology, 1984, Volume: 31, Issue:6

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hyper

1984
Treatment of bleeding varices: controversy and opportunity.
    Hospital practice (Office ed.), 1984, Volume: 19, Issue:4

    Topics: Clinical Trials as Topic; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestina

1984
Selective and non-selective beta receptor blockade in the reduction of portal pressure in patients with cirrhosis and portal hypertension.
    Gut, 1984, Volume: 25, Issue:2

    Topics: Cardiac Output; Female; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male; Meto

1984
Continuous prazosin administration in cirrhotic patients: effects on portal hemodynamics and on liver and renal function.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Blood Pressure; Female; Furosemide; Glomerular Filtration

1995
[Portal hypertension: value of combination of nitrate derivatives and beta blockers for better prevention?].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:3

    Topics: Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate;

1995
Noninvasive measurement of femoral blood flow and portal pressure response to propranolol in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:1

    Topics: Aged; Double-Blind Method; Female; Femoral Vein; Hepatic Veins; Humans; Hypertension, Portal; Liver

1995
Hemodynamic and pharmacokinetic study of tertatolol in patients with alcoholic cirrhosis and portal hypertension.
    Journal of hepatology, 1993, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis, Al

1993
Effects of propranolol on gastric mucosal perfusion and serum gastrin level in cirrhotic patients with portal hypertensive gastropathy.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:11

    Topics: Double-Blind Method; Female; Gastric Mucosa; Gastrins; Gastrointestinal Hemorrhage; Humans; Hyperten

1994
Prevention of rebleeding from oesophageal varices: two-year follow up of a prospective controlled trial of propranolol in addition to sclerotherapy.
    Journal of hepatology, 1994, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Pressure; Combined Modality Therapy; Esophageal and Gastric Varices;

1994
Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:5

    Topics: Adult; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hum

1994
Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: long-term hemodynamic and renal effects.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:6

    Topics: Aldosterone; Analysis of Variance; Body Water; Chi-Square Distribution; Dinoprostone; Drug Therapy,

1994
Duplex Doppler ultrasonographic comparison of the effects of propranolol and isosorbide-5-mononitrate on portal hemodynamics.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1993, Volume: 12, Issue:9

    Topics: Delayed-Action Preparations; Double-Blind Method; Drug Monitoring; Esophageal and Gastric Varices; F

1993
The effect of propranolol on portal perfusion in patients with alcoholic cirrhosis having distal splenorenal shunt.
    Journal of hepatology, 1994, Volume: 20, Issue:1

    Topics: Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Male; Middle Aged; P

1994
Reduction of variceal pressure by propranolol: comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:5

    Topics: Adult; Aged; Azygos Vein; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointesti

1993
A prospective randomized study to evaluate propranolol in patients undergoing long-term endoscopic sclerotherapy.
    Journal of hepatology, 1993, Volume: 19, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Combined Modality Therapy; Double-Blind Method; Endoscopy;

1993
Propranolol compared with propranolol plus isosorbide dinitrate in portal-hypertensive patients: long-term hemodynamic and renal effects.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:3

    Topics: Blood Pressure; Body Weight; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Rate; Hemod

1993
Effects of propranolol on gastric mucosal perfusion in cirrhotic patients with portal hypertensive gastropathy.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:2

    Topics: Female; Gastric Mucosa; Hemodynamics; Humans; Hypertension, Portal; Injections, Intravenous; Laser-D

1993
Effects of propranolol compared with clonidine on portal haemodynamics: a double-blind cross-over study using duplex-Doppler ultrasonography.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:9

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Blood Flow Velocity; Blood Pressure; Clonidine; Cro

1995
The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Ascites; Atrial Natriuretic Factor;

1996
Sclerotherapy versus sclerotherapy and propranolol in the prevention of rebleeding from oesophageal varices: a randomised study.
    Gut, 1996, Volume: 38, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Combined Modality Therapy; Esophageal and Gastric Varices; Fem

1996
Propranolol plus molsidomine vs propranolol alone in the treatment of portal hypertension in patients with cirrhosis.
    Journal of hepatology, 1996, Volume: 24, Issue:4

    Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension, Portal

1996
Weakness of mucosal barrier in portal hypertensive gastropathy of alcoholic cirrhosis. Effects of propranolol and enprostil.
    Journal of hepatology, 1995, Volume: 23, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Anti-Ulcer Agents; Aspirin; Dinoprostone; Enprostil; Femal

1995
Non-invasive variceal pressure measurements: validation and clinical implications.
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1996, Volume: 58, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Determination; Double-Blind Method; Esophageal

1996
Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: the good, the bad, the ugly.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Adrenergic beta-Antagonists; Humans; Hypertension, Portal; Isosorbide Dinitrate; Propranolol; Vasodi

1997
Assessment of effects of propranolol on portal hemodynamics in cirrhosis by duplex ultrasonography.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1998, Volume: 17, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antihypertensive Agents; Cross-Over Studies; Hemodynamics; Humans

1998
Propranolol plus prazosin compared with propranolol plus isosorbide-5-mononitrate in the treatment of portal hypertension.
    Gastroenterology, 1998, Volume: 115, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Drug Therapy, Combination; Female;

1998
Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding.
    The New England journal of medicine, 1999, Apr-01, Volume: 340, Issue:13

    Topics: Adrenergic beta-Antagonists; Adult; Endoscopy; Esophageal and Gastric Varices; Female; Gastrointesti

1999
Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastr

1999
Carvedilol, a new nonselective beta-blocker with intrinsic anti- Alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure;

1999
Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 29, Issue:1

    Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Esophageal and Gastric Varices; Female

1999
Propranolol stereoisomer plasma concentrations and portal haemodynamic response in patients with liver cirrhosis.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:11

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Area Under Curve; Female; Hemodynamics; Humans

1999
A comparative study of the elective treatment of variceal hemorrhage with beta-blockers, transendoscopic sclerotherapy, and surgery: a prospective, controlled, and randomized trial during 10 years.
    Annals of surgery, 2000, Volume: 232, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Endoscopy; Female; Hemorrhage; Humans; Hyperte

2000
Effects of ondansetron on portal hemodynamics in liver cirrhosis.
    International journal of clinical pharmacology and therapeutics, 2000, Volume: 38, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Female; Hemodynamics; Humans; Hyperte

2000
The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial.
    Gastrointestinal endoscopy, 2001, Volume: 53, Issue:6

    Topics: Adult; Aged; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices;

2001
Randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis.
    Gastroenterology, 2001, Volume: 121, Issue:2

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Glomerular

2001
Total effective vascular compliance in patients with cirrhosis. Effects of propranolol.
    Journal of hepatology, 2002, Volume: 36, Issue:3

    Topics: Compliance; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged;

2002
Propranolol ameliorates thrombocytopenia in patients with cirrhosis.
    Journal of gastroenterology, 2002, Volume: 37, Issue:2

    Topics: Adrenergic beta-Antagonists; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Age

2002
Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbazole

2002
Echo-Doppler evaluation of acute flow changes in portal hypertensive patients: flow velocity as a reliable parameter.
    Journal of hepatology, 1992, Volume: 15, Issue:3

    Topics: Aged; Double-Blind Method; Echocardiography, Doppler; Female; Hemodynamics; Humans; Hypertension, Po

1992
[Evaluation of the effects of molsidomine and propranolol-molsidomine combination on portal hemodynamics by pulsed Doppler ultrasound].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:10

    Topics: Adult; Aged; Blood Flow Velocity; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; L

1992
Effects of beta-adrenoreceptor antagonists on cerebral blood flow of cirrhotic patients with portal hypertension.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Cerebral Cortex; Cerebrovascular

1991
Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis.
    Lancet (London, England), 1991, Jun-15, Volume: 337, Issue:8755

    Topics: Actuarial Analysis; Acute Disease; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up

1991
[Prevention of recurrent hemorrhage in patients with cirrhosis. Results of a controlled trial of propranolol versus endoscopic sclerotherapy].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:11

    Topics: Actuarial Analysis; Adult; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Foll

1991
[Drug therapy of pulmonary and portal hypertension in liver cirrhosis].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension, Portal; Hypertension, Pulmonary; Isosorb

1991
Long-term pharmacologic therapy of portal hypertension.
    The Surgical clinics of North America, 1990, Volume: 70, Issue:2

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Hemodynamics; Humans; Hypertension, Portal; M

1990
Propranolol compared with propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis. A randomized controlled study.
    Annals of internal medicine, 1991, May-15, Volume: 114, Issue:10

    Topics: Aged; Drug Therapy, Combination; Female; Hemodynamics; Hepatic Veins; Humans; Hypertension, Portal;

1991
Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. The Boston-New Haven-Barcelona Portal Hypertension Study Group.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:5

    Topics: Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorr

1991
Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:5

    Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Double-Blind Method; Esophageal and Gastr

1991
Portal hypertension therapy with oral propranolol. A short-term study.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:3

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Humans; Hypertension, Portal;

1990
Efficacy of oral propranolol and injection sclerotherapy in the long-term management of variceal bleeding.
    Digestion, 1990, Volume: 46, Issue:4

    Topics: Administration, Oral; Adult; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu

1990
Controlled trial of propranolol to prevent recurrent variceal bleeding in patients with non-cirrhotic portal fibrosis.
    BMJ (Clinical research ed.), 1989, May-20, Volume: 298, Issue:6684

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Vari

1989
Pharmacodynamic and pharmacokinetic study of propranolol in patients with cirrhosis and portal hypertension.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:6

    Topics: Adrenergic beta-Antagonists; Delayed-Action Preparations; Exercise; Heart Rate; Humans; Hypertension

1989
A randomised controlled trial of propranolol for the prevention of initial bleeding in cirrhotic patients with portal hypertension. Preliminary results. The Italian Multicenter Project for Propranolol in the Prevention of Bleeding.
    Drugs, 1989, Volume: 37 Suppl 2

    Topics: Aged; Female; Gastrointestinal Hemorrhage; Hepatitis B Surface Antigens; Humans; Hypertension, Porta

1989
[Propranolol in the prevention of digestive bleeding in cirrhotic patients].
    Acta gastroenterologica Latinoamericana, 1989, Volume: 19, Issue:1

    Topics: Blood Pressure; Cardiac Output; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Ga

1989
[Pharmacological therapy of portal hypertension].
    Schweizerische medizinische Wochenschrift, 1985, Oct-19, Volume: 115, Issue:42

    Topics: Acute Disease; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Esophageal an

1985
Drug therapy for portal hypertension.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Animals; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemo

1986
Comparative haemodynamic effects of betaxolol and propranolol in patients with cirrhosis.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Female; Humans; Hypertension, Portal; Liver Circulati

1988
The effects of propranolol on hepatic encephalopathy in patients with cirrhosis and portal hypertension.
    Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:2

    Topics: Adult; Aged; Double-Blind Method; Electroencephalography; Female; Hepatic Encephalopathy; Humans; Hy

1988
Propranolol or endoscopic sclerotherapy in the prevention of recurrence of variceal bleeding. A prospective, randomized controlled trial.
    Journal of hepatology, 1988, Volume: 7, Issue:2

    Topics: Adult; Clinical Trials as Topic; Endoscopy; Esophageal and Gastric Varices; Female; Follow-Up Studie

1988
Venous, arterial, and arterialized-venous blood ammonia levels and their relationship to hepatic encephalopathy after propranolol.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:3

    Topics: Ammonia; Arteries; Hepatic Encephalopathy; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Prop

1988
A randomized clinical trial of propranolol for the prevention of initial bleeding in cirrhosis with portal hypertension.
    The New England journal of medicine, 1986, Jan-23, Volume: 314, Issue:4

    Topics: Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis

1986
[Controlled study of propranolol in the prevention of recurrent hemorrhage in cirrhotic patients].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointe

1987
Ideal treatment of portal hypertension in 1985.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Acute Disease; Clinical Trials as Topic; Double-Blind Method; Endoscopy; Esophageal and Gastric Vari

1985

Other Studies

183 other studies available for propranolol and Hypertension, Portal

ArticleYear
[CYP2D6 gene polymorphic markers role in determining the optimal treatment tactics for portal hypertension in patients with liver cirrhosis].
    Terapevticheskii arkhiv, 2022, Feb-15, Volume: 94, Issue:2

    Topics: Adrenergic Antagonists; Cytochrome P-450 CYP2D6; Hemodynamics; Humans; Hypertension, Portal; Liver C

2022
Effect of beta-blockers on multiple haemodynamics in cirrhosis: A cross-over study by MR-imaging and hepatic vein catheterization.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:10

    Topics: Adrenergic beta-Antagonists; Ascites; Catheterization; Cross-Over Studies; Hemodynamics; Hepatic Vei

2023
KASL clinical practice guidelines for liver cirrhosis: Varices, hepatic encephalopathy, and related complications.
    Clinical and molecular hepatology, 2020, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Ammonia; Anti-Bacterial Agents; Carvedilol; Disaccharides; Endoscopy, G

2020
Diagnosis and management of extrahepatic oesophageal variceal bleed in children in a low resourced setting.
    Ghana medical journal, 2020, Volume: 54, Issue:4

    Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Esophageal and Gastric Varices; Female;

2020
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Pregnancy in a patient with portal hypertension secondary to liver cirrhosis.
    BMJ case reports, 2018, Mar-05, Volume: 2018

    Topics: Adult; Antihypertensive Agents; Cardiotocography; Esophageal and Gastric Varices; Female; Gastrointe

2018
Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Nov-14, Volume: 51, Issue:12

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonis

2018
Transjugular intrahepatic portosystemic shunt prevents rebleeding in cirrhotic patients having cavernous transformation of the portal vein without improving their survival.
    Journal of digestive diseases, 2019, Volume: 20, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gas

2019
Metabolomics discloses potential biomarkers to predict the acute HVPG response to propranolol in patients with cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Biomarkers; Female; Humans; Hypertension, Portal; Infusions, Intr

2019
Liver volume index predicts the risk of esophageal variceal hemorrhage in cirrhotic patients on propranolol prophylaxis.
    The Korean journal of internal medicine, 2019, Volume: 34, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Decision Support Techniques; Esophageal and Gastric Varice

2019
Impact of non-selective beta blockers on portal hypertension and hepatic elasticity in hepatitis C virus-related liver cirrhosis.
    Drug discoveries & therapeutics, 2019, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Case-Control Studies; Disease Progression; Elasticity Imaging Technique

2019
Hemodynamic response to propranolol in patients with recurrent hepatitis C virus-related cirrhosis after liver transplantation: a case-control study.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2013, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Case-Control Studies; Female; Hemodynam

2013
An unusual cause of delayed puberty: Berardinelli- Seip syndrome.
    Journal of pediatric endocrinology & metabolism : JPEM, 2012, Volume: 25, Issue:11-12

    Topics: Administration, Cutaneous; Adolescent; Atorvastatin; Combined Modality Therapy; Diet, Fat-Restricted

2012
Propranolol treatment of portal hypertension in cirrhosis patients is better the higher the untreated pressure: a single-centre prospective experience.
    Scandinavian journal of gastroenterology, 2013, Volume: 48, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; D

2013
Comparative portal hypotensive effects as propranolol of vitamin D₃ treatment by decreasing intrahepatic resistance in cirrhotic rats.
    Journal of gastroenterology and hepatology, 2015, Volume: 30, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Cholecalciferol; Disease Models, Animal; Drug Therapy, Combina

2015
Investigation of cardiomyopathy in children with cirrhotic and noncirrhotic portal hypertension.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 60, Issue:2

    Topics: Adolescent; Antihypertensive Agents; Ascites; Blood Pressure; Cardiomyopathies; Case-Control Studies

2015
Extrahepatic portal vein obstruction in Egyptian children.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 60, Issue:1

    Topics: Child; Child, Preschool; Cohort Studies; Diagnosis, Differential; Egypt; Esophageal and Gastric Vari

2015
β-Blocker therapy ameliorates hypersplenism due to portal hypertension in children.
    Hepatology international, 2015, Volume: 9, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Biopsy; Child; Child, Preschool; Female; Humans; Hypersplen

2015
Can hypersplenism secondary to portal hypertension be treated by non-selective beta blockers?
    Hepatology international, 2015, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Female; Humans; Hypersplenism; Hypertension, Portal; Male; Propranolol

2015
β-2 Adrenergic receptor gene polymorphism and response to propranolol in cirrhosis.
    World journal of gastroenterology, 2015, Jun-21, Volume: 21, Issue:23

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Case-Control Studies; Esophageal and Gastric V

2015
Metformin reduces hepatic resistance and portal pressure in cirrhotic rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Sep-01, Volume: 309, Issue:5

    Topics: Animals; Blood Pressure; Hypertension, Portal; Liver; Liver Cirrhosis; Male; Metformin; Portal Vein;

2015
Combined administration of propranolol + AG490 offers better effects on portal hypertensive rats with cirrhosis.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:5

    Topics: Acute-Phase Proteins; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Bacterial Trans

2016
Red signs and not severity of cirrhosis should determine non-selective β-blocker treatment in Child-Pugh C cirrhosis with small varices: increased risk of hepatorenal syndrome and death beyond 6 months of propranolol use.
    Gut, 2016, Volume: 65, Issue:7

    Topics: Adrenergic beta-Antagonists; Ascites; Child; Esophageal and Gastric Varices; Hepatorenal Syndrome; H

2016
Propranolol improves endothelial dysfunction in advanced cirrhosis: the 'endothelial exhaustion' hypothesis.
    Gut, 2016, Volume: 65, Issue:8

    Topics: Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol

2016
The anti-inflammatory role of propranolol in cirrhosis: Preventing the inflammatory exhaustion?
    Journal of hepatology, 2017, Volume: 66, Issue:1

    Topics: Anti-Inflammatory Agents; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cirrho

2017
Secondary prophylaxis for variceal bleeding: carvedilol vs. propranolol.
    Hepatology international, 2017, Volume: 11, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Drug Monitoring; Esophageal and

2017
Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2009, Volume: 42, Issue:1

    Topics: Animals; Carbon Tetrachloride; Esophageal and Gastric Varices; Hypertension, Portal; Liver Cirrhosis

2009
Combined use of propranolol and nifedipine offers better effects on portal vein nonuniform remodeling in carbon tetrachloride (CCl(4))-induced portal hypertensive rats.
    European journal of pharmacology, 2009, Jun-24, Volume: 613, Issue:1-3

    Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Carbon Tetrachloride; Drug Combinati

2009
Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension.
    Journal of hepatology, 2009, Volume: 51, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Cohort Studies; Female; Hemorrhage; Humans; Hypertension, Portal;

2009
Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Endosonography; Esophageal and Gastric Varices; Esophag

2009
Effect of early propranolol administration on portal hypertensive gastropathy in cirrhotic rats.
    World journal of gastroenterology, 2009, Sep-14, Volume: 15, Issue:34

    Topics: Animals; Disease Models, Animal; Gastric Mucosa; Hypertension, Portal; Liver Cirrhosis, Experimental

2009
Role of beta3-adrenoceptors for intrahepatic resistance and portal hypertension in liver cirrhosis.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:6

    Topics: Animals; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Hepatic Stellate Cells; Humans; Hypertens

2009
The haemodynamic response to propranolol in cirrhosis with arterial hypertension: a comparative analysis with normotensive cirrhotic patients.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Case-Control Studies; Female; Hemodynamics

2010
Non-invasive measurement of cardiac output by Finometer in patients with cirrhosis.
    Clinical physiology and functional imaging, 2010, Volume: 30, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiac Output; Diagnostic Techniques, Cardiovascular; Equ

2010
Is this really the end of beta-blockers in patients with cirrhosis and refractory ascites?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:2

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Humans; Hypertension, Portal; Liver Cirrhos

2011
Refractory iron-deficiency anaemia in a child with portal cavernoma.
    Gut, 2011, Volume: 60, Issue:3

    Topics: Anemia, Iron-Deficiency; Antihypertensive Agents; Child; Hemangioma, Cavernous; Humans; Hypertension

2011
An uncommon cause of portal hypertension: schistosomiasis.
    The American journal of medicine, 2011, Volume: 124, Issue:2

    Topics: Adult; Animals; Anthelmintics; Antihypertensive Agents; Hepatomegaly; Humans; Hypertension, Portal;

2011
[Beta-blockers in portal hypertension: Unexpected limitations!].
    Presse medicale (Paris, France : 1983), 2011, Volume: 40, Issue:3

    Topics: Adrenergic beta-Antagonists; Cause of Death; Esophageal and Gastric Varices; Esophagoscopy; Gastroin

2011
The effect of rectal ozone on the portal vein oxygenation and pharmacokinetics of propranolol in liver cirrhosis (a preliminary human study).
    British journal of clinical pharmacology, 2011, Volume: 71, Issue:3

    Topics: Adult; Area Under Curve; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Function Tests; Male;

2011
β-blockers and refractory ascites in cirrhosis: the message of a team of true scientists.
    Journal of hepatology, 2011, Volume: 55, Issue:4

    Topics: Adrenergic beta-Antagonists; Ascites; Bacterial Infections; Cardiovascular Diseases; Female; Hepator

2011
Important details to be clarified about the effect of rectal ozone on the portal vein oxygenation.
    British journal of clinical pharmacology, 2011, Volume: 72, Issue:2

    Topics: Humans; Hypertension, Portal; Liver Cirrhosis; Male; Ozone; Portal Vein; Propranolol; Vasodilator Ag

2011
Propranolol modulates the collateral vascular responsiveness to vasopressin via a G(α)-mediated pathway in portal hypertensive rats.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Arginine Vasopressin; Collateral Circ

2011
Non-selective β-blockers improve the correlation of liver stiffness and portal pressure in advanced cirrhosis.
    Journal of gastroenterology, 2012, Volume: 47, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Elasticity; Elasticity Imaging Technique

2012
Effects of the combined administration of propranolol plus sorafenib on portal hypertension in cirrhotic rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, May-15, Volume: 302, Issue:10

    Topics: Animals; Antihypertensive Agents; Benzenesulfonates; Drug Therapy, Combination; Hypertension, Portal

2012
Insulin resistance in patients with cirrhosis and portal hypertension.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Jun-15, Volume: 302, Issue:12

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Insulin Resistance; Liver; Liver Ci

2012
Portal hypertension in children.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Child; Endoscopy, Digestive System; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Li

2012
Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:5

    Topics: Animals; Antiparkinson Agents; Bile Ducts; Blood Pressure; Carbidopa; Carbon Tetrachloride; Disease

2012
Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices.
    Journal of pediatric gastroenterology and nutrition, 2013, Volume: 56, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Child; Child, Preschool; Endoscopy, Gastrointestinal; Esoph

2013
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Body Weight; Carbon Tetrachloride; Ca

2013
Pharmacologic efficacy in gastric variceal rebleeding and survival: including multivariate analysis.
    Journal of clinical gastroenterology, 2002, Volume: 35, Issue:2

    Topics: Adrenergic beta-Antagonists; Carcinoma, Hepatocellular; Esophageal and Gastric Varices; Female; Gast

2002
Acute propranolol administration effectively decreases portal pressure in patients with TIPS dysfunction. Transjugular intrahepatic portosystemic shunt.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adult; Antihypertensive Agents; Cardiac Output; Heart Rate; Humans; Hypertension, Portal; Middle Age

2003
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:4

    Topics: Antihypertensive Agents; Ascites; Bacterial Infections; Cohort Studies; Drug Therapy, Combination; F

2003
"A la carte" treatment of portal hypertension or just "hors d'oeuvres".
    Gastroenterology, 2003, Volume: 124, Issue:7

    Topics: Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Losar

2003
Does losartan work after all?
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Antihypertensive Agents; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Propranolol; Rando

2003
Long-term outcome after sclerotherapy with or without a beta-blocker for variceal bleeding in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2003, Volume: 45, Issue:4

    Topics: Antihypertensive Agents; Child; Child, Preschool; Combined Modality Therapy; Esophageal and Gastric

2003
Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2003, Volume: 13, Issue:9

    Topics: Antihypertensive Agents; Endoscopy, Digestive System; Esophageal and Gastric Varices; Gastrointestin

2003
Reversal of portal hypertension in a patient with primary biliary cirrhosis: disappearance of esophageal varices and thrombocytopenia.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:9

    Topics: Biopsy, Needle; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Follow-Up Studies

2004
[Variceal hemorrhage: primary and secondary prophylaxis].
    Deutsche medizinische Wochenschrift (1946), 2004, Sep-03, Volume: 129 Suppl 2

    Topics: Adrenergic beta-Antagonists; Algorithms; Esophageal and Gastric Varices; Esophagoscopy; Gastrointest

2004
[Cirrhotic cardiomyopathy: prolonged QTc-interval and dyssynchronic electrical and mechanical systole in cirrhosis].
    Ugeskrift for laeger, 2004, Aug-23, Volume: 166, Issue:35

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathies; Electrocardiography; Female; Heart; Hemo

2004
Optimal use of propranolol in portal hypertension.
    Gastroenterologie clinique et biologique, 2005, Volume: 29, Issue:2

    Topics: Antihypertensive Agents; Drug Administration Schedule; Humans; Hypertension, Portal; Propranolol

2005
[Pharmacological therapy of portal hypertension--focused on Korean data].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005, Volume: 45, Issue:6

    Topics: Adrenergic beta-Antagonists; Hepatic Veins; Humans; Hypertension, Portal; Korea; Liver Cirrhosis; Pr

2005
The effect of a combined treatment with propranolol and isosorbide-5-mononitrate on Doppler ultrasound parameters in patients with cirrhosis and portal hypertension.
    Romanian journal of gastroenterology, 2005, Volume: 14, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Drug Therapy, Combination; Female; Follow-U

2005
Effects of norepinephrine and acetylcholine on portal-systemic collaterals of common bile duct-ligated cirrhotic rat.
    Journal of gastroenterology and hepatology, 2005, Volume: 20, Issue:12

    Topics: Acetylcholine; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertens

2005
Influence of beta-2 adrenergic receptor gene polymorphism on the hemodynamic response to propranolol in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:1

    Topics: Adult; Aged; Female; Genotype; Haplotypes; Heart Rate; Hepatic Veins; Humans; Hypertension, Portal;

2006
Effects of propranolol on venous compliance in conscious rats with pre-hepatic portal hypertension.
    Journal of hepatology, 2006, Volume: 44, Issue:6

    Topics: Animals; Blood Pressure; Compliance; Hypertension, Portal; Male; Portal Vein; Propranolol; Rats; Rat

2006
[Hemorrhage due to peristomal ectopic varices: an infrequent complication of portal hypertension].
    Gastroenterologia y hepatologia, 2006, Volume: 29, Issue:5

    Topics: Cecal Neoplasms; Colonic Neoplasms; Diabetes Mellitus, Type 2; Duodenal Ulcer; Gastrointestinal Hemo

2006
Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents?
    European journal of gastroenterology & hepatology, 2006, Volume: 18, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Colostomy; Gastrointestinal Hemorrhage; Humans;

2006
[The effect of angiotensin II type 1 receptor blocker valsartan in rats with portal hypertensive gastropathy].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2006, Volume: 14, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Gastric Mucosa; Hypertension, Portal; Male; Propra

2006
Portal systemic collateral development: is it a trophic adaptation mechanism to hepatic deprivation?
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:11

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Collateral

2006
A patient with diabetes mellitus and recurrent peristomal bleeding.
    The Netherlands journal of medicine, 2006, Volume: 64, Issue:8

    Topics: Aged; Antihypertensive Agents; Colostomy; Diabetes Mellitus, Type 2; Diagnosis, Differential; Electr

2006
The low incidence of bacterial infections could be a protective factor against variceal bleeding per se in hemodynamic responders to propranolol.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:10

    Topics: Antihypertensive Agents; Bacterial Infections; Esophageal and Gastric Varices; Gastrointestinal Hemo

2006
Zhi-fuzi, a cardiotonic Chinese herb, a new medical treatment choice for portal hypertension?
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:4

    Topics: Aconitum; Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Drug Evaluation, Prec

2007
Management practices for gastrointestinal hemorrhage related to portal hypertension in cirrhotic patients: evaluation of the impact of the Paris consensus workshop.
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:11

    Topics: Adrenergic beta-Antagonists; Antibiotic Prophylaxis; Drug Utilization; France; Gastrointestinal Hemo

2007
Propranolol and portal hypertension in cirrhosis.
    Lancet (London, England), 1980, Aug-23, Volume: 2, Issue:8191

    Topics: Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol

1980
Propranolol for portal hypertension.
    Lancet (London, England), 1981, Jun-13, Volume: 1, Issue:8233

    Topics: Humans; Hypertension, Portal; Propranolol

1981
Risk of hepatic encephalopathy in patients taking propranolol for portal hypertension.
    Lancet (London, England), 1982, Sep-04, Volume: 2, Issue:8297

    Topics: Hepatic Encephalopathy; Humans; Hypertension, Portal; Propranolol; Risk

1982
Portal hypertension, propranolol, and hepatic encephalopathy.
    Lancet (London, England), 1982, Oct-16, Volume: 2, Issue:8303

    Topics: Hepatic Encephalopathy; Humans; Hypertension, Portal; Liver Cirrhosis; Portacaval Shunt, Surgical; P

1982
Propranolol increases arterial ammonia in liver cirrhosis.
    Lancet (London, England), 1982, Oct-30, Volume: 2, Issue:8305

    Topics: Adult; Aged; Ammonia; Arteries; Chronic Disease; Fatty Liver, Alcoholic; Female; Humans; Hypertensio

1982
Drug therapy of portal hypertension due to cirrhosis.
    Seminars in liver disease, 1982, Volume: 2, Issue:3

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Por

1982
[Beta-blockers and portal hypertension].
    La Revue du praticien, 1984, Apr-01, Volume: 34, Issue:19

    Topics: Adrenergic beta-Antagonists; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrho

1984
Drug therapy of portal hypertension and oesophageal varices.
    British journal of hospital medicine, 1984, Volume: 32, Issue:1

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1984
Medical treatment of portal hypertension and oesophageal varices.
    British medical journal (Clinical research ed.), 1983, Oct-15, Volume: 287, Issue:6399

    Topics: Animals; Humans; Hypertension, Portal; Liver Circulation; Propranolol; Rats

1983
Effect of propranolol and sclerotherapy in bleeding esophageal varices. A case report.
    Acta chirurgica Scandinavica, 1984, Volume: 150, Issue:1

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Huma

1984
[Liver bypass model following portosystemic anastomoses in children with portal hypertension].
    Padiatrie und Grenzgebiete, 1983, Volume: 22, Issue:6

    Topics: Adult; Blood Glucose; Child; Child, Preschool; Humans; Hypertension, Portal; Kinetics; Phenylalanine

1983
Effect of intravenous propranolol on portal hypertension.
    The Journal of the Association of Physicians of India, 1984, Volume: 32, Issue:4

    Topics: Adult; Female; Humans; Hypertension, Portal; Injections, Intravenous; Male; Middle Aged; Propranolol

1984
Propranolol: its role in the management of portal hypertension. The ACG Committee on FDA related matters.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:2

    Topics: Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Propranolo

1983
[Propranolol treatment of hemorrhage due to portal hypertension].
    La Nouvelle presse medicale, 1981, Mar-21, Volume: 10, Issue:13

    Topics: Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranolol

1981
[Medical treatment of hemorrhage in portal hypertension of the cirrhotic patient using propanolol].
    Medecine & chirurgie digestives, 1982, Volume: 11, Issue:1

    Topics: Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol; Recurrence

1982
Effect of propranolol on hepatic blood flow in normal and portal hypertensive rats.
    Clinical science (London, England : 1979), 1982, Volume: 63, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Heart Rate; Hypertension, Portal; Liver Circulation; Male;

1982
[Physiopathological bases of the medical treatment of portal hypertension].
    Giornale di clinica medica, 1982, Volume: 63, Issue:10

    Topics: Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Propranolol; Vascula

1982
Effects of propranolol on intestinal microcirculation of normal and portal hypertensive rats.
    Journal of hepatology, 1995, Volume: 22, Issue:6

    Topics: Animals; Drug Administration Routes; Hemodynamics; Hypertension, Portal; Intestines; Male; Microcirc

1995
[Study of gastric mucosal lesion in portal hypertension].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:8

    Topics: Antihypertensive Agents; Esophageal and Gastric Varices; Gastric Mucosa; Gastroscopy; Humans; Hypert

1995
IgA nephropathy associated with portal hypertension in liver cirrhosis due to non-alcoholic and non-A, non-B, non-C hepatitis.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:8

    Topics: Aged; Female; Glomerulonephritis, IGA; Hepatitis; Humans; Hypertension, Portal; Kidney Glomerulus; L

1994
Hemodynamic responses to selective blockade of beta 2- and beta 1-adrenoceptors in conscious rats with cirrhosis.
    Journal of hepatology, 1994, Volume: 21, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Combinations; Hemodynamics; Hypertension, Porta

1994
Shunt surgery and beta-blockers.
    Journal of hepatology, 1994, Volume: 20, Issue:1

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cir

1994
Effects of beta-adrenoceptor antagonists on portal vein hypertension and ethanol-induced gastric mucosal damage in rats.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; L

1994
[Per-rectal scintigraphy of the portal system with pertechnetate TC-99M: effect of propranolol on portosystemic collateral circulation in patients with cirrhosis. Part II].
    Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 92, Issue:1

    Topics: Adult; Aged; Blood Pressure; Collateral Circulation; Esophageal and Gastric Varices; Female; Gastroi

1994
[Addition of ritanserin to the treatment with propranolol in cirrhotic patients: effects on portal pressure].
    Anales de medicina interna (Madrid, Spain : 1984), 1994, Volume: 11, Issue:4

    Topics: Adult; Aged; Drug Therapy, Combination; Humans; Hypertension, Portal; Middle Aged; Propranolol; Rita

1994
Hemodynamic effects of nipradilol, a new beta-adrenergic antagonist combined with a nitroxy base, in rats with intra- or extra-hepatic portal hypertension.
    Journal of hepatology, 1993, Volume: 17, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Blood Circulation; Hemodynamics; Hypertension, Portal; Male; P

1993
Cardiovascular hyporesponsiveness to norepinephrine, propranolol and nitroglycerin in portal-hypertensive and aged rats.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:1

    Topics: Aging; Animals; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Heart Rate;

1993
Bleeding varices due to portal hypertension in sarcoidosis. Favorable effect of propranolol and prednisone.
    Chest, 1993, Volume: 103, Issue:2

    Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hype

1993
Effects of terlipressin on hemodynamics and oxygen content in conscious portal vein stenosed and cirrhotic rats receiving propranolol.
    Journal of hepatology, 1993, Volume: 17, Issue:1

    Topics: Animals; Blood Pressure; Carbon Dioxide; Heart Rate; Hemodynamics; Hydrogen-Ion Concentration; Hyper

1993
Propranolol in the control of haemorrhage from varices around a urostomy.
    British journal of urology, 1993, Volume: 71, Issue:5

    Topics: Aged; Anastomosis, Surgical; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

1993
Portal hypertension revisited.
    QJM : monthly journal of the Association of Physicians, 1995, Volume: 88, Issue:11

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Portasyst

1995
Haemodynamic effects of molsidomine and propranolol in patients with cirrhosis.
    British journal of clinical pharmacology, 1996, Volume: 41, Issue:5

    Topics: Adrenergic beta-Antagonists; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans

1996
Haemodynamic effects of combined treatment with molsidomine and propranolol on portal hypertension in conscious and unrestrained cirrhotic rats.
    Journal of gastroenterology and hepatology, 1996, Volume: 11, Issue:10

    Topics: Animals; Drug Therapy, Combination; Hemodynamics; Hypertension, Portal; Liver Cirrhosis, Experimenta

1996
Systemic and hepatic hemodynamics in hepatosplenic Manson's schistosomiasis with and without propranolol.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Esophageal and Gastric Varices; Hemodynamic

1997
Prevention of portal hypertension by propranolol and spironolactone in rats with bile duct ligation.
    Journal of hepatology, 1997, Volume: 26, Issue:1

    Topics: Animals; Antihypertensive Agents; Cholestasis; Drug Evaluation, Preclinical; Drug Therapy, Combinati

1997
Chronic administration of propranolol improves vascular contractile responsiveness in portal hypertensive rats.
    European journal of clinical investigation, 1997, Volume: 27, Issue:7

    Topics: Animals; Hemodynamics; Hypertension, Portal; Intubation, Gastrointestinal; Mesenteric Artery, Superi

1997
Haemodynamic effects of octreotide in portal hypertensive rats receiving propranolol.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Drug Interactions; Heart Rate; Hemodynamics; H

1997
Hemodynamic effects of chronic tetrandrine and propranolol administration on portal hypertensive rats.
    Pharmacology, 1997, Volume: 54, Issue:5

    Topics: Administration, Oral; Alkaloids; Analysis of Variance; Animals; Antihypertensive Agents; Benzylisoqu

1997
Long-term treatment of bleeding caused by portal hypertension in children.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Administration, Oral; Adult; Child; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal

1997
Hemodynamic effects of eight-day octreotide and propranolol administration in portal hypertensive rats.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Drug Therapy, Combination; Hemodynamics; Hormones; Hypertensio

1998
Noninvasive hemodynamic measurements of superior mesenteric artery in the prediction of portal pressure response to propranolol.
    Journal of hepatology, 1998, Volume: 28, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Female; Hemodynamics; Hum

1998
Clinical vs haemodynamic response to drugs in portal hypertension.
    Journal of hepatology, 1998, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Esophageal and Gastric Varices; Female; Follow-Up Studi

1998
Noninvasive endoscopic determination of intravariceal pressure in patients with portal hypertension: clinical experience with a new balloon technique.
    Endoscopy, 1998, Volume: 30, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Case-Control Studies; Endoscopy, Digestive System; Equipment D

1998
Increased angiogenesis in portal hypertensive rats: role of nitric oxide.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Disease Models, Animal; Hypertension, Portal; Ima

1999
[Evaluation of propranolol response by catheterization and Doppler ultrasonography in patients with cirrhosis].
    Acta gastroenterologica Latinoamericana, 1998, Volume: 28, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Catheterization; Female; Humans; Hypertension, Portal; Liv

1998
Propranolol and portal hypertension: should kids be on the block?
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 29, Issue:1

    Topics: Antihypertensive Agents; Child; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans;

1999
An advance in the treatment of portal hypertension?
    Gastroenterology, 2000, Volume: 118, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Humans; Hypertens

2000
Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension.
    Gastroenterology, 2000, Volume: 119, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta; Atenolol; Constriction, Pathol

2000
Betablocker, hepatic functions and confusion.
    The Journal of the Association of Physicians of India, 1999, Volume: 47, Issue:2

    Topics: Adrenergic beta-Antagonists; Confusion; Humans; Hypertension, Portal; Liver Cirrhosis; Liver Functio

1999
Re: Orozco et al. A comparative study of the elective treatment of variceal hemorrhage with beta-blockers, transendoscopic sclerotherapy and surgery. A prospective, controlled, and randomized trial during 10 years. Ann Surg 2000; 232:216-9.
    Annals of surgery, 2001, Volume: 234, Issue:1

    Topics: Adrenergic beta-Antagonists; Hemorrhage; Humans; Hypertension, Portal; Propranolol; Sclerotherapy; V

2001
Effect of beta-adrenergic blockade on elevated arterial compliance and low systemic vascular resistance in cirrhosis.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:6

    Topics: Adrenergic beta-Antagonists; Female; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosi

2001
Systemic and splanchnic hemodynamics following hemorrhage and volume restitution with Haemaccel in portal hypertensive rats: the effect of propranolol.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Heart

2001
Discussion on randomized comparison of long-term losartan versus propranolol in lowering portal pressure in cirrhosis.
    Gastroenterology, 2002, Volume: 122, Issue:5

    Topics: Antihypertensive Agents; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Losartan; Male; Prop

2002
[Measurement of liver circulation by means of an ultrasonic Doppler flow measuring device].
    Fortschritte der Medizin, 1977, Oct-13, Volume: 95, Issue:38

    Topics: Animals; Blood Flow Velocity; Dogs; Doppler Effect; Hepatic Artery; Hypertension, Portal; Ligation;

1977
[Colostomy-induced varices in portal hypertension].
    Chirurgie; memoires de l'Academie de chirurgie, 1992, Volume: 118, Issue:4

    Topics: Aged; Colon; Colostomy; Female; Humans; Hypertension, Portal; Male; Middle Aged; Prognosis; Proprano

1992
Propranolol for portal hypertensive gastropathy: another virtue of beta-blockade?
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrho

1992
Long-term haemodynamic effects of a 4-week regimen of nipradilol, a new beta-blocker with nitrovasodilating properties, in patients with portal hypertension due to cirrhosis. A comparative study with propranolol.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Female; Hemodynamics; Humans; Hypertension

1992
[Duplex ultrasound studies of the portal vein system. Hemodynamic changes in liver cirrhosis].
    Fortschritte der Medizin, 1992, Aug-20, Volume: 110, Issue:23

    Topics: Blood Flow Velocity; Humans; Hypertension, Portal; Liver Cirrhosis; Portal Vein; Propranolol; Ultras

1992
Portal pressure response to propranolol in portal hypertension.
    Journal of hepatology, 1992, Volume: 15, Issue:1-2

    Topics: Blood Pressure; Humans; Hypertension, Portal; Portal Vein; Propranolol

1992
Combined treatment of portal hypertension with ritanserin and propranolol in conscious and unrestrained cirrhotic rats.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:5

    Topics: Animals; Consciousness; Drug Therapy, Combination; Hemodynamics; Hypertension, Portal; Liver Cirrhos

1992
[Adrenergic beta blockade in liver cirrhosis with portal hypertension? Doppler ultrasound measurement of the short-term effect of propranolol on the portal system].
    Zeitschrift fur arztliche Fortbildung, 1992, Apr-27, Volume: 86, Issue:7-8

    Topics: Blood Flow Velocity; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage;

1992
Beta-blockers in portal hypertension: variation on a theme.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:7

    Topics: Acute Disease; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranolol

1992
Early chronic administration of propranolol reduces the severity of portal hypertension and portal-systemic shunts in conscious portal vein stenosed rats.
    Journal of hepatology, 1991, Volume: 13, Issue:2

    Topics: Animals; Collateral Circulation; Constriction, Pathologic; Hemodynamics; Hypertension, Portal; Male;

1991
[Propranolol in portal hypertensive gastropathy].
    Deutsche medizinische Wochenschrift (1946), 1991, Dec-13, Volume: 116, Issue:50

    Topics: Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol; Stomach Dis

1991
[Pharmacological lowering of portal pressure in normal rats and in experimental liver cirrhosis].
    Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR, 1991, Volume: 51, Issue:3-4

    Topics: Acute Disease; Animals; Blood Pressure; Canrenoic Acid; Heart Rate; Hypertension, Portal; Liver Cirr

1991
[Sclerosing treatment of esophageal varices].
    Acta gastroenterologica Latinoamericana, 1991, Volume: 21, Issue:2

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; L

1991
Propranolol ameliorates the development of portal-systemic shunting in a chronic murine schistosomiasis model of portal hypertension.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:3

    Topics: Animals; Blood Pressure; Chronic Disease; Collagen; Granuloma; Heart Rate; Hemodynamics; Hepatic Art

1991
The influence of propanolol on portosystemic shunting.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:5

    Topics: Animals; Blood Circulation; Hypertension, Portal; Mice; Mice, Inbred C3H; Portal System; Propranolol

1991
[Prevention of gastrointestinal hemorrhage caused by portal thrombosis with propranolol. Report of a case with an 8 year follow-up].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:11

    Topics: Aged; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Male; Portal Vei

1990
Enhancement of portal pressure reduction by the association of isosorbide-5-mononitrate to propranolol administration in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:2

    Topics: Aged; Blood Pressure; Female; Hemodynamics; Humans; Hypertension, Portal; Isosorbide Dinitrate; Live

1990
Effects of propranolol on arterial oxygenation and oxygen transport to tissues in patients with cirrhosis.
    The American review of respiratory disease, 1990, Volume: 142, Issue:2

    Topics: Female; Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Oxygen; Prop

1990
Effects of propranolol on gastric microcirculation and acid secretion in portal hypertensive rats.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:3 Pt 1

    Topics: Animals; Disease Models, Animal; Drug Interactions; Gastric Acid; Gastric Mucosa; Hypertension, Port

1990
Effects of propranolol and nitroglycerin on portal pressure and the mechanism of their reducing portal pressure.
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 1

    Topics: Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Nitroglyce

1989
Hyperkinetic circulatory syndrome in patients with presinusoidal portal hypertension. Effect of propranolol.
    Journal of hepatology, 1989, Volume: 9, Issue:3

    Topics: Adult; Collateral Circulation; Female; Gastrointestinal Hemorrhage; Heart Rate; Hemodynamics; Hepati

1989
[The use of anaprilin for the correction of portal hypertension in liver cirrhosis].
    Vrachebnoe delo, 1989, Issue:11

    Topics: Adult; Aged; Ascites; Drug Evaluation; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hy

1989
Portasystemic shunt fraction quantification using transrectal administration of iodine-123 iodoamphetamine in dogs with chronic bile duct ligation and after propranolol administration.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:10

    Topics: Amphetamines; Animals; Bile Ducts; Dogs; Hemodynamics; Hypertension, Portal; Iodine Radioisotopes; L

1989
Treatment options in portal hypertension: Does propranolol have a role? Proceedings of a satellite symposium of the XIII International Congress of Gastroenterology and the VI European Congress of Digestive Endoscopy. Rome, 9 September 1988.
    Drugs, 1989, Volume: 37 Suppl 2

    Topics: Humans; Hypertension, Portal; Propranolol

1989
Effect of selective blockade of beta 2-adrenergic receptors on portal and systemic hemodynamics in a portal hypertensive rat model.
    Gastroenterology, 1985, Volume: 88, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cardiac Output; Heart Rate; Hemodyna

1985
Combination of ketanserin and verapamil or propranolol in patients with alcoholic cirrhosis: search for an additive effect.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:1

    Topics: Drug Synergism; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Portal; Ketanserin; L

1989
Discrepancy between portal pressure and systemic hemodynamic changes after incremental doses of propranolol in awake portal hypertensive rats.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:2

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Hear

1989
Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:2

    Topics: Animals; Esophageal and Gastric Varices; Esophagoscopy; Hemodynamics; Hypertension, Portal; Liver; M

1989
Haemodynamic rebound phenomena after abrupt cessation of propranolol therapy in portal hypertensive rats.
    Journal of hepatology, 1986, Volume: 3, Issue:1

    Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hypertens

1986
Effects of alpha-adrenergic stimulation and beta-adrenergic blockade on azygos blood flow and splanchnic haemodynamics in patients with cirrhosis.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Azygos Vein; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis;

1987
Rheohepatogram as a parameter in assessing immediate effects of propranolol on portal hypertension.
    Chinese medical journal, 1986, Volume: 99, Issue:1

    Topics: Adult; Female; Heart Rate; Humans; Hypertension, Portal; Liver Circulation; Male; Middle Aged; Pleth

1986
[The effects of propranolol or nitroglycerin on azygos blood flow in patients with portal hypertension].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1986, Volume: 83, Issue:8

    Topics: Azygos Vein; Humans; Hypertension, Portal; Nitroglycerin; Propranolol; Regional Blood Flow

1986
Effects of propranolol and nitroglycerin on cephalad collateral venous flow in patients with cirrhosis: evaluation using transesophageal real-time two-dimensional Doppler echography.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:11

    Topics: Aged; Aorta; Azygos Vein; Blood Flow Velocity; Collateral Circulation; Color; Female; Humans; Hypert

1988
[Hemorrhage caused by portal hypertension at the level of a colostomy. Efficacy of propranolol?].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:2

    Topics: Colostomy; Female; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Middle Aged; Propranol

1988
Persistent hemorrhagic gastritis in a patient with portal hypertension and esophagogastric varices: the role of portal decompressive surgery.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:7

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Hypert

1988
[Effect of propranolol on intrahepatic portal hypertension in the rat].
    Revista medica de Chile, 1987, Volume: 115, Issue:3

    Topics: Animals; Blood Pressure; Carbon Tetrachloride Poisoning; Female; Heart Rate; Hypertension, Portal; L

1987
[Effects of sotalol on blocked suprahepatic pressure in cirrhotic patients].
    Annales de gastroenterologie et d'hepatologie, 1987, Volume: 23, Issue:7

    Topics: Aged; Blood Pressure; Cardiac Output; Cough; Female; Hepatic Veins; Humans; Hypertension, Portal; Li

1987
[Prevention of recurrent hemorrhage due to portal hypertension].
    Schweizerische medizinische Wochenschrift, 1986, Apr-26, Volume: 116, Issue:17

    Topics: Double-Blind Method; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Hum

1986
[Behavior of blood ammonia, insulin, glucagon, renin and prolactin during propranolol therapy in cirrhosis patients with portal hypertension].
    La Clinica terapeutica, 1986, Jul-31, Volume: 118, Issue:2

    Topics: Adult; Aged; Ammonia; Dose-Response Relationship, Drug; Drug Evaluation; Female; Glucagon; Humans; H

1986
Effects of propranolol and sucralfate on ethanol-induced gastric mucosal damage in chronic portal hypertensive rats.
    Journal of hepatology, 1987, Volume: 5, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Hypertension, Portal; Male; Prop

1987
[Medical therapy of portal hypertension].
    La Clinica terapeutica, 1986, May-31, Volume: 117, Issue:4

    Topics: Atenolol; Cardiac Output; Humans; Hypertension, Portal; Metoprolol; Propranolol

1986
[Portal hypertension in children. Therapeutic approach in cases of failure of a portosystemic shunt].
    Chirurgie pediatrique, 1986, Volume: 27, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Esophagea

1986
Hemodynamic effect of propranolol on portal hypertension in patients with HBsAg-positive cirrhosis.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:12

    Topics: Adult; Aged; Cardiac Output; Heart Rate; Hemodynamics; Hepatitis B; Hepatitis B Surface Antigens; Hu

1986
[Indications for surgery in portal hypertension from the internist's viewpoint].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1985, Volume: 56, Issue:7

    Topics: Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal;

1985
Superior portosystemic collateral circulation estimated by azygos blood flow in patients with cirrhosis. Lack of correlation with oesophageal varices and gastrointestinal bleeding. Effect of propranolol.
    Journal of hepatology, 1985, Volume: 1, Issue:1

    Topics: Azygos Vein; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hu

1985
Effects of propranolol on portal hemodynamics in patients with chronic liver disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:2

    Topics: Adult; Aged; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Hypertension, Portal; Mal

1985
[Rheohepatographic assessment of the therapeutic effects of propranolol on portal hypertension].
    Zhonghua yi xue za zhi, 1985, Volume: 65, Issue:7

    Topics: Adult; Aged; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis;

1985
Propranolol reduces ethanol-induced gastric mucosal damage in portal hypertensive rats.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:2

    Topics: Animals; Blood Pressure; Ethanol; Gastric Mucosa; Hypertension, Portal; Male; Necrosis; Portal Syste

1986
Pharmacology of propranolol in patients with cirrhosis and portal hypertension.
    Gut, 1985, Volume: 26, Issue:1

    Topics: Aged; Female; Heart Rate; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Proprano

1985
Effect of propranolol on renal blood flow in portal hypertensive rats.
    Gastroenterology, 1985, Volume: 88, Issue:3

    Topics: Animals; Hypertension, Portal; Propranolol; Rats; Renal Circulation

1985
Propranolol therapy for portal hypertension in children.
    The Journal of pediatrics, 1985, Volume: 106, Issue:2

    Topics: Adolescent; Anemia; Blood Pressure; Cardiac Output; Child; Child, Preschool; Female; Humans; Hyperte

1985
Propranolol for portal hypertension. Evaluation of therapeutic response by direct measurement of portal vein pressure.
    Archives of internal medicine, 1985, Volume: 145, Issue:4

    Topics: Blood Pressure; Blood Pressure Determination; Heart Rate; Humans; Hypertension, Portal; Liver Diseas

1985
Variceal bleeding from an ileostomy stoma.
    Southern medical journal, 1985, Volume: 78, Issue:6

    Topics: Hemorrhage; Humans; Hypertension, Portal; Ileostomy; Ileum; Ligation; Male; Middle Aged; Propranolol

1985
Comparison of the short-term effects of mepindolol and propranolol on splanchnic and systemic haemodynamics in patients with cirrhosis.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Adult; Female; Hemodynamics; Humans; Hypertension, Portal; Liver Circulation; Liver Cirrhosis; Male;

1985
Acute effect of propranolol on splanchnic circulation in normal and portal hypertensive rats.
    Journal of hepatology, 1985, Volume: 1, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Hepatic Artery; Hypertension, Portal; Male; Portal Vein; Pr

1985
[The effect of propranolol on portal hypertension in patients with varices after esophageal transection].
    Nihon Geka Gakkai zasshi, 1985, Volume: 86, Issue:8

    Topics: Esophageal and Gastric Varices; Esophagus; Hemodynamics; Humans; Hypertension, Portal; Postoperative

1985
[Chronotropic effect of a combined injection of calcium ions and beta-receptor blockaders].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Mar-15, Volume: 26, Issue:6

    Topics: Adrenergic beta-Antagonists; Blood Pressure Determination; Calcium; Drug Synergism; Electrocardiogra

1971