Page last updated: 2024-11-03

propranolol and Hyperlipidemias

propranolol has been researched along with Hyperlipidemias in 28 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research Excerpts

ExcerptRelevanceReference
"The effects of propranolol and proteinuria on the fasting lipoprotein profiles of 33 male renal allograft recipients have been studied."7.66The role of propranolol therapy and proteinuria in the etiology of post renal transplantation hyperlipidemia. ( Jackson, JM; Lee, HA, 1982)
"The metabolic effects of celiprolol, a new beta-adrenoceptor blocking agent with intrinsic sympathomimetic activity and alpha 2-blocking properties, were evaluated in a series of patients with hypertension, both with and without hyperlipidemia."5.06Lipid effects of celiprolol, a new cardioselective beta-blocker, versus propranolol. ( Cremoncini, M; Dujovne, CA; Gianfranceschi, G; Johnson, B; Montanari, G; Sirtori, CR; Sirtori, M; Vaccarino, V, 1989)
"Subjective discomfort caused by nausea and hot, pruritic skin has been described in patients after ingestion of therapeutic dosages of niacin is shown by this study to be alleviated by propranolol HC1."5.04Preliminary report of the effects of propranolol HCl on the discomfiture caused by niacin. ( Estep, DL; Gay, GR; Rappolt, RT, 1977)
" Addition of eugenosedin-A to the high-fat diet resulted in less weight gain and reduced hyperglycaemia, hyperinsulinaemia and hyperlipidaemia."3.75Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet. ( Chen, IJ; Hsieh, SL; Kwan, AL; Lin, HL; Shen, KP; Wu, BN, 2009)
"The effects of propranolol and proteinuria on the fasting lipoprotein profiles of 33 male renal allograft recipients have been studied."3.66The role of propranolol therapy and proteinuria in the etiology of post renal transplantation hyperlipidemia. ( Jackson, JM; Lee, HA, 1982)
"The lipophilic beta-adrenoreceptor antagonist propranolol and hydrophilic atenolol have been studied to define their pharmacokinetic and pharmacodynamic characteristics in obese patients."2.71Comparative pharmacokinetics and pharmacodynamics of propranolol and atenolol in normolipaemic and hyperlipidaemic obese subjects. ( Droździk, M; Gawrońska-Szklarz, B; Jaroszynska, M; Pawlik, A; Sterna, R; Wójcicki, J, 2003)
" In the light of the results obtained, the following conclusions were drawn: 1) hyperlipidemia affects pharmacodynamic properties of lipophilic propranolol and hydrophilic atenolol, 2) a modification of the drug dosage in hyperlipidemia is warranted."2.71[Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol]. ( Droździk, M; Gawrońska-Szklarz, B; Sterna, R; Sulzyc-Bielicka, V; Telatyńska-Smieszek, B; Wójcicki, J, 2004)
" Pharmacokinetic parameters were calculated according to the noncompartmental open model."2.70[Pharmacokinetic comparison of propranolol and atenolol in people with primary hypertension]. ( Telatyńska-Smieszek, B, 2002)
"Propranolol was given orally as a single dose of 80 mg."2.69Studies on the pharmacokinetics and pharmacodynamics of propranolol in hyperlipidemia. ( Droździk, M; Gawrońska-Szklarz, B; Kutrzeba, J; Sterna, Z; Sulzyc-Bielicka, V; Wójcicki, J, 1999)
"Propranolol was given orally as a single dose 80 mg."2.68[The effect of hypolipemic treatment on the pharmacokinetics of propranolol]. ( Sterna, R, 1997)
"Propranolol was given intragastrically at a single dose of 80 mg [corrected]."1.30[Effect of hydroxylation polymorphism on the concentration of propranolol in the blood of humans with hyperlipidemia]. ( Droździk, M; Gawrońska-Szklarz, B; Kunicki, P; Sitkiewicz, D; Sterna, R; Sulzyc-Bielicka, V; Wójcicki, J, 1999)
"Propranolol was used and proved to reduce the fluctuations of total cholesterol."1.26Intraindividual variability of plasma cholesterol and triglycerides and the effect of propranolol treatment. ( Rühling, K; Schauer, I; Thielmann, K, 1980)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's5 (17.86)18.2507
2000's5 (17.86)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duan, L1
Ng, A1
Chen, W1
Spencer, HT1
Nguyen, J1
Shen, AY1
Lee, MS1
Shen, KP1
Lin, HL1
Hsieh, SL1
Kwan, AL1
Chen, IJ1
Wu, BN1
Wójcicki, J4
Jaroszynska, M1
Droździk, M4
Pawlik, A1
Gawrońska-Szklarz, B4
Sterna, R4
Telatyńska-Smieszek, B2
Sulzyc-Bielicka, V3
Isaza, C1
Henao, J1
Ramirez, E1
Cuesta, F1
Cacabelos, R1
Spence, JD1
Perkins, DG1
Kline, RL1
Adams, MA1
Haust, MD1
Dujovne, CA2
DeCoursey, S1
Krehbiel, P1
Jackson, B1
Chernoff, S1
Jackson, JM1
Lee, HA1
Bielmann, P2
Leduc, G2
Davignon, J1
Rühling, K1
Schauer, I1
Thielmann, K1
Bagatin, J1
Sardelić, S1
Pivac, N1
Polić, S1
Ljutic, D1
Rakic, D1
Naranca, M1
Bojić, L1
Kovacić, Z1
Rumboldt, Z1
Kutrzeba, J1
Sterna, Z1
Kunicki, P1
Sitkiewicz, D1
Simons, LA1
Myant, NB1
Estep, DL1
Gay, GR1
Rappolt, RT1
Chobanian, AV1
Sirtori, CR1
Johnson, B1
Vaccarino, V1
Montanari, G1
Cremoncini, M1
Gianfranceschi, G1
Sirtori, M1
Metelitsa, VI1
Oganov, RG1
Grzywa, M1
Brook, JG1
Marmur, A1
Berkovitch, Y1
Aviram, M1
Whitaker, AN1
Bunce, I1
Knowles, BR1
Richardson, ER1
Olefsky, JM1
Farquhar, JW1
Reaven, GM1
Miyahara, M1
Ashinaga, T1
Morikawa, R1
Minemawari, Y1
Lipson, MJ1
Naimi, S1
Proger, S1

Reviews

1 review available for propranolol and Hyperlipidemias

ArticleYear
[Catecholamines and arteriosclerosis].
    Horumon to rinsho. Clinical endocrinology, 1972, Volume: 20, Issue:8

    Topics: Adrenal Glands; Angina Pectoris; Arteriosclerosis; Catecholamines; Depression, Chemical; Epinephrine

1972

Trials

11 trials available for propranolol and Hyperlipidemias

ArticleYear
Comparative pharmacokinetics and pharmacodynamics of propranolol and atenolol in normolipaemic and hyperlipidaemic obese subjects.
    Biopharmaceutics & drug disposition, 2003, Volume: 24, Issue:5

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Area Under Curve; Atenolol; Blood Pressure

2003
[Pharmacokinetic comparison of propranolol and atenolol in people with primary hypertension].
    Annales Academiae Medicae Stetinensis, 2002, Volume: 48

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cross-Over Studies; Female; Humans; Hyperlipidemias; M

2002
[Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 111, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Area Under Curve; Atenolol; Blood Pressure; Chrom

2004
Polymorphic variants of the beta2-adrenergic receptor (ADRB2) gene and ADRB2-related propanolol-induced dyslipidemia in the Colombian population.
    Methods and findings in experimental and clinical pharmacology, 2005, Volume: 27, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Cholesterol, HDL; Colombia; Female;

2005
Serum lipids in normo- and hyperlipidemics after methyldopa and propranolol.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:2

    Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Female; Humans; Hyperlipidemias; Hypertension; Lipids; L

1984
[The effect of hypolipemic treatment on the pharmacokinetics of propranolol].
    Annales Academiae Medicae Stetinensis, 1997, Volume: 43

    Topics: Administration, Oral; Anticholesteremic Agents; Bezafibrate; Chromatography, High Pressure Liquid; D

1997
Comparison of chlorthalidone, propranolol and bopindolol in six-month treatment of arterial hypertension.
    International journal of clinical pharmacology research, 1998, Volume: 18, Issue:2

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; Chlorthalidone; Double-Blind Method; Female; Humans; Hyp

1998
Studies on the pharmacokinetics and pharmacodynamics of propranolol in hyperlipidemia.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:8

    Topics: Adult; Anti-Arrhythmia Agents; Area Under Curve; Blood Pressure; Female; Heart Rate; Humans; Hyperli

1999
Preliminary report of the effects of propranolol HCl on the discomfiture caused by niacin.
    Clinical toxicology, 1977, Volume: 11, Issue:3

    Topics: Clinical Trials as Topic; Humans; Hyperlipidemias; Nausea; Nicotinic Acids; Propranolol; Pruritus

1977
Effects of metoprolol and propranolol on lipid metabolism.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:9

    Topics: Cholesterol; Double-Blind Method; Humans; Hyperlipidemias; Lipid Metabolism; Metoprolol; Propanolami

1979
Lipid effects of celiprolol, a new cardioselective beta-blocker, versus propranolol.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Celiprolol; Cholesterol; Chromatography, High Pressure Liq

1989

Other Studies

16 other studies available for propranolol and Hyperlipidemias

ArticleYear
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi

2017
Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:4

    Topics: Adipose Tissue; Animals; Atorvastatin; Blood Glucose; Body Weight; Brain; Dietary Fats; Female; Glut

2009
Hemodynamic modification of aortic atherosclerosis. Effects of propranolol vs hydralazine in hypertensive hyperlipidemic rabbits.
    Atherosclerosis, 1984, Volume: 50, Issue:3

    Topics: Animals; Aortic Diseases; Arteriosclerosis; Cholesterol; Hemodynamics; Hydralazine; Hyperlipidemias;

1984
The role of propranolol therapy and proteinuria in the etiology of post renal transplantation hyperlipidemia.
    Clinical nephrology, 1982, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Humans; Hyperlipidemias; Kidney

1982
[Selective beta blockaders (metoprolol) versus non selective (propranolol): comparative effects on the composition of lipoprotein fractions and on blood pressure].
    L'union medicale du Canada, 1980, Volume: 109, Issue:12

    Topics: Blood Pressure; Cholesterol; Double-Blind Method; Female; Humans; Hyperlipidemias; Hypertension; Lip

1980
Intraindividual variability of plasma cholesterol and triglycerides and the effect of propranolol treatment.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Adult; Cholesterol; Humans; Hyperlipidemias; Individuality; Lipoproteins, HDL; Male; Middle Aged; Pr

1980
[Effect of hydroxylation polymorphism on the concentration of propranolol in the blood of humans with hyperlipidemia].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999, Volume: 7, Issue:42

    Topics: Adolescent; Adult; Antihypertensive Agents; Female; Humans; Hydroxylation; Hyperlipidemias; Male; Mi

1999
Cholesterol metabolism in hypertriglyceridaemia and the effects of treatment.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Nov-15, Volume: 65, Issue:1

    Topics: Adult; Alcohol Drinking; Bile Acids and Salts; Cholesterol; Chylomicrons; Diabetes Complications; Di

1975
The effects of ACE inhibitors and other antihypertensive drugs on cardiovascular risk factors and atherogenesis.
    Clinical cardiology, 1990, Volume: 13, Issue:6 Suppl 7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteriosclerosis; Calciu

1990
System approach to testing hypotensive drugs for prevention of arterial hypertension.
    Cor et vasa, 1987, Volume: 29, Issue:5

    Topics: Clinical Trials as Topic; Humans; Hydralazine; Hyperlipidemias; Hypertension; Prazosin; Propranolol

1987
Serum somatomedin activity and growth hormone level in obese men: dependence on degree of obesity and hyperlipidemia.
    Experimental and clinical endocrinology, 1986, Volume: 88, Issue:3

    Topics: Adult; Body Weight; Growth Hormone; Humans; Hyperlipidemias; Levodopa; Male; Middle Aged; Obesity; P

1986
Platelet adhesion in hyperlipidemic and hypertensive patients.
    Haemostasis, 1985, Volume: 15, Issue:6

    Topics: Adult; Arteriosclerosis; Atenolol; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinem

1985
Hyperlipidemia in experimental disseminated intravascular coagulation.
    The Journal of trauma, 1974, Volume: 14, Issue:2

    Topics: Aminocaproates; Analysis of Variance; Angiotensin II; Animals; Cholesterol; Disseminated Intravascul

1974
Reappraisal of the role of insulin in hypertriglyceridemia.
    The American journal of medicine, 1974, Volume: 57, Issue:4

    Topics: Administration, Oral; Adult; Aged; Blood Glucose; Diet; Epinephrine; Female; Glucose; Glucose Tolera

1974
Angina pectoris--II.
    British medical journal, 1971, Mar-06, Volume: 1, Issue:5748

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Cholesterol; Cholestyramine Resin; Clofibrate; D

1971
Effect of a combination of propranolol and nicotinic acid on the inhibition of norepinephrine-induced elevations of serum triglyceride, serum glycerol, and plasma free fatty acids in the dog.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:6

    Topics: Animals; Cholesterol; Depression, Chemical; Dogs; Drug Antagonism; Drug Synergism; Fatty Acids, None

1971