propranolol has been researched along with Hypercapnia in 42 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of a single oral dose of propranolol on the ventilatory response to hypercapnia has been studied in five healthy subjects." | 9.04 | Effect of propranolol on the ventilatory response to hypercapnia in man. ( Taylor, EA; Trembath, PW; Turner, P; Varley, J, 1979) |
| "The cerebral blood flow (CBF) and cerebral oxygen consumption (CMRO2) in the rat during normocapnia and hypercapnia were investigated by means of the intraarterial 133Xenon injection technique; measurements were performed during normocapnia and hypercapnia and the effect of propranolol upon CBF and CMRO2 was studied." | 7.66 | The effect of propranolol on cerebral oxygen consumption and blood flow in the rat: measurements during normocapnia and hypercapnia. ( Barry, DI; Hemmingsen, R; Hertz, MM, 1979) |
| "Neotenic larval Ambystoma tigrinum were subjected to hypercapnia (3% CO2, 22 Torr) for 24 h under different conditions: alpha-adrenergic blockade using phentolamine, beta-adrenergic blockade using propranolol, and sham treatments." | 3.68 | Acid-base-electrolyte balance responses to catecholamine antagonists in Ambystoma tigrinum. ( Boutilier, RG; Kopecky, ME; Stiffler, DF; Thompson, ML, 1990) |
| "In anesthetized dogs, differences in the haemodynamic effects of propranolol and oxprenolol were observed during normoxia, hypercapnia and hypoxia." | 3.65 | [Proceedings: Experimental hemodynamic comparison of propranolol and oxprenolol]. ( Stepanek, J, 1975) |
| " Halothane anaesthesia sensitized the equine heart to the arrhythmogenic actions of adrenaline; the incidence and duration of ventricular arrhythmias being greater than in conscious animals." | 3.65 | Influence of halothane and catecholamines on heart rate and rhythm in the horse. ( Lees, P; Tavernor, WD, 1970) |
| "Pretreatment with propranolol completely abolished the increase in hypercapnic ventilatory response, but did not affect the other changes." | 2.64 | The effects of smoked marijuana on metabolism and respiratory control. ( Doekel, R; Hammill, S; Weil, JV; Zwillich, CW, 1978) |
| "After propranolol treatment, respiratory acidosis further reduced Emax (4." | 1.28 | Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs. ( Lewis, TH; Walley, KR; Wood, LD, 1990) |
| " The results support the concept that increased autonomic activity in combination with acute arterial hypoxia and hypercapnea contribute significantly to the exhibition of serious cardiac rhythm disturbances." | 1.26 | Effects of hypercapnea and of hypercapnea in combination with hypoxia on midbrain-induced cardiac dysrhythmias. ( Clendenin, MA; Forbes, JE; Mauck, HP; Newton, RA; szumski, AJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (90.48) | 18.7374 |
| 1990's | 3 (7.14) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urboniene, D | 1 |
| Dias, FA | 1 |
| Peña, JR | 1 |
| Walker, LA | 1 |
| Solaro, RJ | 1 |
| Wolska, BM | 1 |
| Patel, L | 1 |
| Turner, P | 2 |
| Rose, CE | 1 |
| Godine, RL | 1 |
| Rose, KY | 1 |
| Anderson, RJ | 1 |
| Carey, RM | 1 |
| Siesjö, BK | 1 |
| Folgering, H | 1 |
| Braakhekke, J | 1 |
| Hutchinson, PF | 1 |
| Harrison, RN | 1 |
| Hemmingsen, R | 1 |
| Hertz, MM | 1 |
| Barry, DI | 1 |
| Edvinsson, L | 1 |
| Lacombe, P | 1 |
| Owman, C | 1 |
| Reynier-Rebuffel, AM | 1 |
| Seylaz, J | 1 |
| Mattiazzi, AR | 1 |
| Cingolani, HE | 1 |
| Sodipo, JO | 1 |
| Lee, DC | 1 |
| Morris, LE | 1 |
| Marotta, SF | 1 |
| Sithichoke, N | 1 |
| Garcy, AM | 1 |
| Yu, M | 1 |
| Taylor, JF | 1 |
| Lee, JC | 1 |
| Downing, SE | 2 |
| Zwillich, CW | 1 |
| Doekel, R | 1 |
| Hammill, S | 1 |
| Weil, JV | 1 |
| Trembath, PW | 1 |
| Taylor, EA | 1 |
| Varley, J | 1 |
| Mauck, HP | 1 |
| szumski, AJ | 1 |
| Forbes, JE | 1 |
| Clendenin, MA | 1 |
| Newton, RA | 1 |
| Stepanek, J | 1 |
| Stiffler, DF | 1 |
| Kopecky, ME | 1 |
| Thompson, ML | 1 |
| Boutilier, RG | 1 |
| Walley, KR | 1 |
| Lewis, TH | 1 |
| Wood, LD | 1 |
| Saeki, Y | 1 |
| Sato, A | 1 |
| Sato, Y | 1 |
| Trzebski, A | 1 |
| Wexels, JC | 1 |
| Myhre, ES | 1 |
| Eliades, D | 1 |
| Weiss, HR | 1 |
| Pannier, JL | 1 |
| Lacroix, E | 1 |
| Leusen, I | 1 |
| Foex, P | 1 |
| Prys-Roberts, C | 1 |
| Kontos, HA | 3 |
| Richardson, DW | 3 |
| Patterson, JL | 3 |
| Baïsset, A | 1 |
| Cotonat, J | 1 |
| Montastruc, P | 1 |
| Raper, AJ | 1 |
| Polu, JM | 1 |
| Sadoul, P | 1 |
| Kurimoto, S | 1 |
| Higo, GI | 1 |
| Barta, E | 1 |
| Siska, K | 1 |
| Tréger, J | 1 |
| Holomán, M | 1 |
| Horecký, J | 1 |
| Kuzela, L | 1 |
| Trancík, J | 1 |
| Cerven, J | 1 |
| Spiker, DG | 1 |
| Smith, CW | 1 |
| Halloran, KH | 1 |
| Ithuralde, MM | 1 |
| Pelletier, CL | 1 |
| Shepherd, JT | 1 |
| Pepelko, WE | 1 |
| Cain, SM | 2 |
| Blackburn, JP | 1 |
| Conway, CM | 1 |
| Leigh, JM | 1 |
| Lindop, MJ | 1 |
| Reitan, JA | 1 |
| Székely, M | 1 |
| Kellermayer, M | 1 |
| Donhoffer, S | 1 |
| Petty, WC | 1 |
| Sulkowski, TS | 1 |
| Tashkin, DP | 1 |
| Goldstein, PJ | 1 |
| Simmons, DH | 1 |
| Sterling, GM | 1 |
| Lees, P | 1 |
| Tavernor, WD | 1 |
| Williams, JF | 1 |
| Boyd, DL | 1 |
| Border, JF | 1 |
3 reviews available for propranolol and Hypercapnia
| Article | Year |
|---|---|
Central actions of beta-adrenoceptor blocking drugs in man.
Topics: Adrenergic beta-Antagonists; Animals; Anxiety Disorders; Behavior, Animal; Brain; Haplorhini; Humans | 1981 |
Cerebral metabolic rate in hypercarbia--a controversy.
Topics: Amino Acids; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Citric Acid Cycle; Diazepa | 1980 |
[Medical treatment of arrhythmia during acute respiratory insufficiency].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Catecholamines; Electric Stimulation; Electrocard | 1971 |
5 trials available for propranolol and Hypercapnia
| Article | Year |
|---|---|
Effect of acute and chronic beta-blockade on carbon dioxide sensitivity in normal man.
Topics: Adult; Atenolol; Carbon Dioxide; Female; Heart Rate; Humans; Hypercapnia; Male; Metoprolol; Propanol | 1980 |
The effects of smoked marijuana on metabolism and respiratory control.
Topics: Cannabis; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hypercapnia; Hypoxia; M | 1978 |
Effect of propranolol on the ventilatory response to hypercapnia in man.
Topics: Adult; Female; Humans; Hypercapnia; Male; Propranolol; Respiration; Respiratory Function Tests | 1979 |
Contribution of hypercapnia and hypoxia to the vascular response to ischaemia.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; B | 1970 |
The mechanism of decreased specific airway conductance in man during hypercapnia caused by inhalation of 7 per cent CO2.
Topics: Airway Resistance; Atropine; Bronchi; Carbon Dioxide; Humans; Hypercapnia; Larynx; Metaproterenol; P | 1969 |
34 other studies available for propranolol and Hypercapnia
| Article | Year |
|---|---|
Expression of slow skeletal troponin I in adult mouse heart helps to maintain the left ventricular systolic function during respiratory hypercapnia.
Topics: Acidosis; Animals; Blood Gas Analysis; Calcium; Calcium-Binding Proteins; Diastole; Female; Hypercap | 2005 |
Role of arginine vasopressin and angiotensin II in cardiovascular responses to combined acute hypoxemia and hypercapnic acidosis in conscious dogs.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cardiac Output; Dogs; Female; Glucose; Heart Rate; He | 1984 |
Ventilatory response to hypercapnia in normal subjects after propranolol, metoprolol and oxprenolol.
Topics: Adult; Carbon Dioxide; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hu | 1980 |
The effect of propranolol on cerebral oxygen consumption and blood flow in the rat: measurements during normocapnia and hypercapnia.
Topics: Animals; Brain; Cerebrovascular Circulation; Hydrogen-Ion Concentration; Hypercapnia; Oxygen Consump | 1979 |
Quantitative changes in regional cerebral blood flow of rats induced by alpha- and beta-adrenergic stimulants.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbon Dioxide; Cerebrovascular Circul | 1979 |
Biphasic effect of hypercapnia on myocardial contractility.
Topics: Animals; Calcium; Carbon Dioxide; Cats; Hydrogen-Ion Concentration; Hypercapnia; Myocardial Contract | 1977 |
Modification by propranolol of cardiovascular response to hypercapnia during halothane anaesthesia.
Topics: Anesthesia; Animals; Carbon Dioxide; Dogs; Halothane; Hemodynamics; Hypercapnia; Propranolol | 1979 |
Adrenocortical responses of rats to acute hypoxic and hypercapnic stresses after treatment with aminergic agents.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Biogenic Amines; Bis(4-Methyl- | 1976 |
Effects of acidosis, catechols, and atrial function on pulmonary pressure gradients.
Topics: Acidosis; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cardiac Output; Cats; Female | 1975 |
Effects of hypercapnea and of hypercapnea in combination with hypoxia on midbrain-induced cardiac dysrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Cats; Heart Rate; Hypercapn | 1976 |
[Proceedings: Experimental hemodynamic comparison of propranolol and oxprenolol].
Topics: Animals; Dogs; Drug Evaluation; Hypercapnia; Hypoxia; Oxprenolol; Propranolol | 1975 |
Acid-base-electrolyte balance responses to catecholamine antagonists in Ambystoma tigrinum.
Topics: Acid-Base Equilibrium; Ambystoma; Animals; Carbon Dioxide; Catecholamines; Electrolytes; Electrophys | 1990 |
Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs.
Topics: Acidosis, Respiratory; Acute Disease; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; | 1990 |
Effects of stimulation of cervical sympathetic trunks with various frequencies on the local cortical cerebral blood flow measured by laser Doppler flowmetry in the rat.
Topics: Animals; Blood Flow Velocity; Cerebrovascular Circulation; Electric Stimulation; Hypercapnia; Lasers | 1990 |
Hypocapnia and hypercapnia in the dog: effects on myocardial blood-flow and haemodynamics during beta- and combined alpha- and beta-adrenoceptor blockade.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Circulation; Dogs; Epinephrine; He | 1987 |
Effect of hypercapnia on coronary circulation.
Topics: Acidosis; Animals; Blood Pressure; Carotid Body; Coronary Circulation; Denervation; Electric Stimula | 1986 |
Effects of adrenergic blockade on the hemodynamic response to acute experimental hypercapnia.
Topics: Acidosis, Respiratory; Acute Disease; Adrenergic alpha-Antagonists; Allyl Compounds; Animals; Blood | 1972 |
Interactions of beta-receptor blockade and PCO2 levles in the anaesthetized dog.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Animals; Body Temperature; Carbon Dioxide; Cardiac | 1974 |
Effects of hypercapnia on human forearm blood vessels.
Topics: Blood Flow Velocity; Blood Pressure; Blood Vessels; Carbon Dioxide; Ethanolamines; Forearm; Humans; | 1967 |
[Enhancement of cardiac and intestinal effects of adrenaline by gaseous hypocapnic alkalosis in the dog].
Topics: Alkalosis; Animals; Cardiac Output; Dogs; Electrocardiography; Epinephrine; Ethanolamines; Hydrogen- | 1967 |
Dynamic circulatory responses to halothane inhalation, hypercapnia and hypoxia in sympathectomized and atropine-propranolol pretreated dogs.
Topics: Animals; Atropine; Blood Pressure; Depression, Chemical; Dogs; Halothane; Heart Rate; Hemodynamics; | 1972 |
Effect of respiratory acid-base disturbance on myocardial potassium movement during extracorporeal circulation of blood.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Buffers; Catecholamines; Cell Membrane Permea | 1973 |
Effect of hypercapnia on myocardial potassium movement in the dog.
Topics: Acidosis, Respiratory; Animals; Biological Transport, Active; Catecholamines; Dogs; Heart Rate; Hype | 1972 |
Relation between acute changes in pH and PCO2 and inotropic responses to acetyl strophanthidin.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood; Blood Pressure; Carbon Dioxide; Cardanolides; Cardi | 1972 |
Venous responses to stimulation of carotid chemoreceptors by hypoxia and hypercapnia.
Topics: Animals; Atropine; Blood Pressure; Carbon Dioxide; Carotid Sinus; Chemoreceptor Cells; Chloralose; D | 1972 |
Cooling of anesthetized paralyzed dogs during hypercapnia and B-adrenergic blockade.
Topics: Animals; Body Temperature; Body Temperature Regulation; Carbon Dioxide; Cold Temperature; Dogs; Hydr | 1972 |
Pa CO2 and the pre-ejection period: the pa CO2 inotropy response curve.
Topics: Adult; Age Factors; Aged; Anesthesia, General; Animals; Biomechanical Phenomena; Carbon Dioxide; Dog | 1972 |
The effect of hypoxia, hypercapnia, -adrenergic blockade and anaesthesia on heat production by periaortic brown adipose tissue.
Topics: Acclimatization; Adipose Tissue, Brown; Anesthesia; Animals; Aorta, Thoracic; Body Temperature Regul | 1971 |
CO 2 narcosis in the rat. II. Effects on the ECG.
Topics: Animals; Arrhythmias, Cardiac; Carbon Dioxide; Doxapram; Electrocardiography; Heart; Heart Block; He | 1971 |
Effect of acute respiratory acidosis on mesenteric circulation of dogs.
Topics: Acidosis, Respiratory; Animals; Bicarbonates; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; C | 1969 |
Influence of halothane and catecholamines on heart rate and rhythm in the horse.
Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Consciousness; Epin | 1970 |
Effect of acute hypoxia and hypercapnic acidosis on the development of acetylstrophanthidin-induced arrhythmias.
Topics: Adrenal Medulla; Adrenalectomy; Alkalosis; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dio | 1968 |
Roles of hypercapnia and acidosis in the vasodilator response to hypercapnic acidosis.
Topics: Acidosis; Bicarbonates; Blood Pressure; Blood Vessels; Carbon Dioxide; Forearm; Heart Rate; Humans; | 1968 |
Diminution of lactate rise during hypoxia by PCO2 and beta-adrenergic blockade.
Topics: Animals; Carbon Dioxide; Cardiac Output; Dogs; Hypercapnia; Hypoxia; Lactates; Oxygen; Oxygen Consum | 1969 |