propranolol has been researched along with Huntington Disease in 8 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Huntington's disease is characterized by striatal degeneration, leading to progressive choreoathetoid movements, dementia and behavioral changes." | 2.37 | Huntington's disease. ( Stewart, JT, 1988) |
| "Initial manifestations of Huntington's disease (HD) are varied and chorea is not always the first motor symptom." | 1.36 | [Postural tremor as first symptom of Huntington disease]. ( Bernard, E; Broussolle, E; Thobois, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernard, E | 1 |
| Broussolle, E | 1 |
| Thobois, S | 1 |
| Whittaker, M | 1 |
| Wicks, RJ | 1 |
| Britten, JJ | 1 |
| Stewart, JT | 4 |
| Fisher, M | 1 |
| Sargent, J | 1 |
| Drachman, D | 1 |
| Mounts, ML | 1 |
| Clark, RL | 1 |
| Marsden, CD | 1 |
1 review available for propranolol and Huntington Disease
| Article | Year |
|---|---|
Huntington's disease.
Topics: Behavior; Family; Family Practice; Humans; Huntington Disease; Propranolol | 1988 |
7 other studies available for propranolol and Huntington Disease
| Article | Year |
|---|---|
[Postural tremor as first symptom of Huntington disease].
Topics: Adrenergic beta-Antagonists; Adult; Dopamine Antagonists; Dystonia; Family; Female; Humans; Huntingt | 2010 |
Studies on the inhibition by propranolol of some human erythrocyte membrane enzymes and plasma cholinesterase.
Topics: Adenosine Triphosphatases; Binding Sites; Ca(2+) Mg(2+)-ATPase; Cholinesterase Inhibitors; Cholinest | 1982 |
Huntington's disease and propranolol.
Topics: Female; Humans; Huntington Disease; Mental Disorders; Middle Aged; Propranolol | 1993 |
Familial inverted choreoathetosis.
Topics: Athetosis; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Huntington Disease; Mal | 1979 |
Aggressive behavior in Huntington's disease: treatment with propranolol.
Topics: Adult; Aggression; Antipsychotic Agents; Drug Therapy, Combination; Haloperidol; Humans; Huntington | 1987 |
Paradoxical aggressive effect of propranolol in a patient with Huntington's disease.
Topics: Aged; Aggression; Humans; Huntington Disease; Male; Neurocognitive Disorders; Propranolol | 1987 |
Drug treatment of diseases characterized by abnormal movements.
Topics: Chorea; Diazepam; Ethanol; Haloperidol; Humans; Huntington Disease; Levodopa; Movement Disorders; My | 1973 |