Page last updated: 2024-11-03

propranolol and Hereditary Hemorrhagic Telangiectasia

propranolol has been researched along with Hereditary Hemorrhagic Telangiectasia in 6 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"The study demonstrated that combined therapy (sclerotherapy and topical nasal propranolol) significantly reduced the epistaxis due to HHT and increased patients' quality of life."7.91Sclerotherapy and Topical Nasal Propranolol: An Effective and Safe Therapy for HHT-Epistaxis. ( Botella Cubells, L; Esteban-Casado, S; Marcos Salazar, MS; Martín de Rosales Cabrera, AM; Martínez Simón, JJ; Pérez Encinas, M; Usarralde Pérez, A; Zhan Zhou, E, 2019)
"These preliminary results suggest that topical propranolol may be effective for the treatment of epistaxis in patients with HHT."7.85Topical propranolol improves epistaxis in patients with hereditary hemorrhagic telangiectasia - a preliminary report. ( Blau, H; Bruckheimer, E; Goldschmidt, N; Mei-Zahav, M; Zur, E, 2017)
" Administration (systemically or topically via a spray or gel) of timolol and propranolol showed mixed evidence of improvement in epistaxis frequency, severity, and duration when compared with control groups."5.22The Use of Beta-Blockers in Hereditary Hemorrhagic Telangiectasia-Related Epistaxis: A Systematic Review. ( Albarki, H; Rimmer, J, 2022)
"The study demonstrated that combined therapy (sclerotherapy and topical nasal propranolol) significantly reduced the epistaxis due to HHT and increased patients' quality of life."3.91Sclerotherapy and Topical Nasal Propranolol: An Effective and Safe Therapy for HHT-Epistaxis. ( Botella Cubells, L; Esteban-Casado, S; Marcos Salazar, MS; Martín de Rosales Cabrera, AM; Martínez Simón, JJ; Pérez Encinas, M; Usarralde Pérez, A; Zhan Zhou, E, 2019)
"These preliminary results suggest that topical propranolol may be effective for the treatment of epistaxis in patients with HHT."3.85Topical propranolol improves epistaxis in patients with hereditary hemorrhagic telangiectasia - a preliminary report. ( Blau, H; Bruckheimer, E; Goldschmidt, N; Mei-Zahav, M; Zur, E, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Albarki, H1
Rimmer, J1
Mei-Zahav, M1
Blau, H1
Bruckheimer, E1
Zur, E1
Goldschmidt, N1
Esteban-Casado, S1
Martín de Rosales Cabrera, AM1
Usarralde Pérez, A1
Martínez Simón, JJ1
Zhan Zhou, E1
Marcos Salazar, MS1
Pérez Encinas, M1
Botella Cubells, L1
Contis, A1
Gensous, N1
Viallard, JF1
Goizet, C1
Léauté-Labrèze, C1
Duffau, P1
Albiñana, V1
Recio-Poveda, L1
Zarrabeitia, R1
Bernabéu, C1
Botella, LM1
Breier, G1

Reviews

1 review available for propranolol and Hereditary Hemorrhagic Telangiectasia

ArticleYear
The Use of Beta-Blockers in Hereditary Hemorrhagic Telangiectasia-Related Epistaxis: A Systematic Review.
    American journal of rhinology & allergy, 2022, Volume: 36, Issue:6

    Topics: Epistaxis; Humans; Propranolol; Prospective Studies; Quality of Life; Randomized Controlled Trials a

2022

Other Studies

5 other studies available for propranolol and Hereditary Hemorrhagic Telangiectasia

ArticleYear
Topical propranolol improves epistaxis in patients with hereditary hemorrhagic telangiectasia - a preliminary report.
    Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2017, Oct-04, Volume: 46, Issue:1

    Topics: Administration, Intranasal; Administration, Topical; Adult; Aged; Dose-Response Relationship, Drug;

2017
Sclerotherapy and Topical Nasal Propranolol: An Effective and Safe Therapy for HHT-Epistaxis.
    The Laryngoscope, 2019, Volume: 129, Issue:10

    Topics: Administration, Intranasal; Administration, Topical; Adult; Aged; Combined Modality Therapy; Cross-S

2019
Efficacy and safety of propranolol for epistaxis in hereditary haemorrhagic telangiectasia: retrospective, then prospective study, in a total of 21 patients.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2017, Volume: 42, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Epistaxis; Female; Humans; Male; Middle Aged; Propranolol;

2017
Propranolol as antiangiogenic candidate for the therapy of hereditary haemorrhagic telangiectasia.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:1

    Topics: Activin Receptors, Type II; Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Animals; Antigens,

2012
Propanolol and angiogenesis inhibition in hereditary haemorrhagic telangiectasia.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Animals; Endothelium, Vascular; Humans; Neovas

2012