propranolol has been researched along with Hemangioblastoma in 4 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Hemangioblastoma: A benign tumor of the nervous system that may occur sporadically or in association with VON HIPPEL-LINDAU DISEASE. It accounts for approximately 2% of intracranial tumors, arising most frequently in the cerebellar hemispheres and vermis. Histologically, the tumors are composed of multiple capillary and sinusoidal channels lined with endothelial cells and clusters of lipid-laden pseudoxanthoma cells. Usually solitary, these tumors can be multiple and may also occur in the brain stem, spinal cord, retina, and supratentorial compartment. Cerebellar hemangioblastomas usually present in the third decade with INTRACRANIAL HYPERTENSION, and ataxia. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2071-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "HeLa 9X (HRE) hypoxia responsive element cell line and primary hemangioblastoma-derived cells were subjected to propranolol treatment and cell viability and apoptosis were evaluated." | 7.81 | Propranolol reduces viability and induces apoptosis in hemangioblastoma cells from von Hippel-Lindau patients. ( Albiñana, V; Botella, LM; de Campos, JM; Mota-Pérez, M; Perona-Moratalla, AB; Segura, T; Serrano-Heras, G; Villar Gómez de Las Heras, K, 2015) |
| "Propranolol was initiated with a progressive increase up to a final dose of 120 mg daily." | 5.46 | Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease. ( Albiñana, V; Botella, LM; Escribano, RMJ; Padial, LR; Recio-Poveda, L; Soler, I; Villar Gómez de Las Heras, K, 2017) |
| "HeLa 9X (HRE) hypoxia responsive element cell line and primary hemangioblastoma-derived cells were subjected to propranolol treatment and cell viability and apoptosis were evaluated." | 3.81 | Propranolol reduces viability and induces apoptosis in hemangioblastoma cells from von Hippel-Lindau patients. ( Albiñana, V; Botella, LM; de Campos, JM; Mota-Pérez, M; Perona-Moratalla, AB; Segura, T; Serrano-Heras, G; Villar Gómez de Las Heras, K, 2015) |
| "Propranolol was initiated with a progressive increase up to a final dose of 120 mg daily." | 1.46 | Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease. ( Albiñana, V; Botella, LM; Escribano, RMJ; Padial, LR; Recio-Poveda, L; Soler, I; Villar Gómez de Las Heras, K, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albiñana, V | 3 |
| Recio-Poveda, L | 2 |
| González-Peramato, P | 1 |
| Martinez-Piñeiro, L | 1 |
| Botella, LM | 3 |
| Cuesta, AM | 1 |
| Escribano, RMJ | 1 |
| Soler, I | 1 |
| Padial, LR | 1 |
| Villar Gómez de Las Heras, K | 2 |
| Hernández-Martínez, P | 1 |
| Gallego-Pinazo, R | 1 |
| Dolz-Marco, R | 1 |
| Arevalo, JF | 1 |
| Díaz-Llopis, M | 1 |
| Cisneros Lanuza, A | 1 |
| Serrano-Heras, G | 1 |
| Segura, T | 1 |
| Perona-Moratalla, AB | 1 |
| Mota-Pérez, M | 1 |
| de Campos, JM | 1 |
4 other studies available for propranolol and Hemangioblastoma
| Article | Year |
|---|---|
Blockade of β2-Adrenergic Receptor Reduces Inflammation and Oxidative Stress in Clear Cell Renal Cell Carcinoma.
Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hemangiobl | 2022 |
Repurposing propranolol as a drug for the treatment of retinal haemangioblastomas in von Hippel-Lindau disease.
Topics: Adolescent; Adult; Biomarkers; Female; Hemangioblastoma; Humans; Male; MicroRNAs; Middle Aged; Propr | 2017 |
Oral propranolol and intravitreal ranibizumab for refractory serous macular detachment secondary to retinal capillary hemangioblastoma.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Angiogenesis Inhibitors; Combined Modality | 2015 |
Propranolol reduces viability and induces apoptosis in hemangioblastoma cells from von Hippel-Lindau patients.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Apoptosis; Cell Survival; Cerebellar Neoplasms; Dose | 2015 |