propranolol has been researched along with Glioma in 30 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In has been found that sphingosine, propranolol, imipramine and phorbol ester (12-O-tetradecanoylphorbol-13-acetate, TPA) have a stimulatory effect on phospholipase D activity in glioma C6 cells." | 7.70 | Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester. ( Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I, 2000) |
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 7.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| "The effects of chlorpromazine (CPZ), desmethylimipramine (DMI) and propranolol (PRO) on phospholipid metabolism in C6 glioma cells were studied by following the incorporation of 32Pi, [U-14C]glycerol, [2-3H]glycerol and [1-14C]oleate into lipids." | 7.67 | Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells. ( Hauser, G; Leli, U, 1987) |
| "The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 7.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
| "Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics." | 5.72 | Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022) |
| " Rat C6 glioma cells were stimulated with isoproterenol and the protein lysates were resolved by 2-DGE." | 3.70 | Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell. ( Khawaja, XZ; Storm, SM, 1999) |
| "In has been found that sphingosine, propranolol, imipramine and phorbol ester (12-O-tetradecanoylphorbol-13-acetate, TPA) have a stimulatory effect on phospholipase D activity in glioma C6 cells." | 3.70 | Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester. ( Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I, 2000) |
| "When exposed to the beta-agonist (-)-isoproterenol, rat glioma C6 cells exhibited a time-and concentration-dependent reduction in isoproterenol responsiveness (desensitization) and a loss of beta-adrenergic receptors (down-regulation)." | 3.67 | Desensitization of catecholamine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells. Role of cyclic AMP and protein synthesis. ( Fishman, PH; Zaremba, TG, 1984) |
| "The action of the (-)- and (+)-enantiomers of the beta-adrenoceptor blocking drug propranolol on the inward calcium current (ICa) was studied in single mouse neuroblastoma x rat glioma hybrid cells of clone 108CC5 by suction pipette technique for intracellular perfusion and voltage clamp." | 3.67 | [Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells]. ( Bodewei, R; Fischer, W; Hering, S; Wollenberger, A, 1988) |
| "The effects of chlorpromazine (CPZ), desmethylimipramine (DMI) and propranolol (PRO) on phospholipid metabolism in C6 glioma cells were studied by following the incorporation of 32Pi, [U-14C]glycerol, [2-3H]glycerol and [1-14C]oleate into lipids." | 3.67 | Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells. ( Hauser, G; Leli, U, 1987) |
| " Therefore, the veratridine- (or aconitine-)stimulated influx of [14C]guanidinium in neuroblastoma x glioma hybrid cells was measured to characterize the Na+ ionophore of these cells." | 3.66 | Blockade by neurotransmitter antagonists of veratridine-activated ion channels in neuronal cell lines. ( Günther, A; Hamprecht, B; Reiser, G, 1983) |
| "The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 3.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
| " The beta-adrenergic receptors of cultured rat C6 glioma cells (2B clone) as assessed by [(125)I]iodohydroxybenzylpindolol binding were decreased 50 and >95% after pretreatment with 8 nM and 1 muM aminobenzylpropranolol, respectively." | 3.66 | Quantitative relationship between beta-adrenergic receptor number and physiologic responses as studied with a long-lasting beta-adrenergic antagonist. ( Brooker, G; Linden, J; Terasaki, WL, 1979) |
| "Malignant gliomas have a highly immune suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics." | 1.72 | Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses. ( Ammons, DT; Boss, MK; Chow, L; Dow, S; Frank, C; Griffin, JF; Guth, A; Kurihara, J; MacQuiddy, B; Makii, R; Marolf, AJ; McGrath, S; Packer, RA; Regan, DP; Rozental, AJ, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (76.67) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ammons, DT | 1 |
| Guth, A | 1 |
| Rozental, AJ | 1 |
| Kurihara, J | 1 |
| Marolf, AJ | 1 |
| Chow, L | 1 |
| Griffin, JF | 1 |
| Makii, R | 1 |
| MacQuiddy, B | 1 |
| Boss, MK | 1 |
| Regan, DP | 1 |
| Frank, C | 1 |
| McGrath, S | 1 |
| Packer, RA | 1 |
| Dow, S | 1 |
| Heumann, R | 1 |
| Reiser, G | 3 |
| Van Calker, D | 1 |
| Hamprecht, B | 4 |
| Homburger, V | 2 |
| Lucas, M | 2 |
| Bockaert, J | 2 |
| Günther, A | 1 |
| Zaremba, TG | 1 |
| Fishman, PH | 1 |
| Gozlan, H | 1 |
| Michelot, R | 1 |
| Münzel, P | 1 |
| Koschel, K | 2 |
| Harrison, JJ | 1 |
| Schwoch, G | 1 |
| Schweppe, JS | 1 |
| Jungmann, RA | 1 |
| Adie, EJ | 1 |
| Milligan, G | 1 |
| Tas, PW | 1 |
| Levi, G | 1 |
| Patrizio, M | 1 |
| Bernardo, A | 1 |
| Petrucci, TC | 1 |
| Agresti, C | 1 |
| Canova, C | 1 |
| Baudet, C | 1 |
| Chevalier, G | 1 |
| Brachet, P | 1 |
| Wion, D | 1 |
| Storm, SM | 1 |
| Khawaja, XZ | 1 |
| Bobeszko, M | 1 |
| Dygas, A | 1 |
| Nalepa, I | 1 |
| Barańska, J | 1 |
| Schmitt, H | 1 |
| Pochet, R | 1 |
| Franklin, TJ | 1 |
| Twose, PA | 1 |
| Terasaki, WL | 1 |
| Linden, J | 1 |
| Brooker, G | 1 |
| Doore, BJ | 1 |
| Bashor, MM | 1 |
| Spitzer, N | 1 |
| Mawe, RC | 1 |
| Saier, MH | 1 |
| Traber, J | 2 |
| Fischer, K | 2 |
| Schlegel, B | 1 |
| Oey, J | 2 |
| Bodewei, R | 1 |
| Fischer, W | 1 |
| Hering, S | 1 |
| Wollenberger, A | 1 |
| Schwartz, JP | 2 |
| Leli, U | 2 |
| Hauser, G | 2 |
| Folbergrová, J | 1 |
| Lisá, V | 1 |
| Drobník, J | 1 |
| Mares, V | 1 |
| Passonneau, JV | 1 |
| Venter, JC | 1 |
| Dixon, JE | 1 |
| Maroko, PR | 1 |
| Kaplan, NO | 1 |
| Gilman, AG | 1 |
| Minna, JD | 1 |
| Latzin, S | 1 |
30 other studies available for propranolol and Glioma
| Article | Year |
|---|---|
Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses.
Topics: Animals; Brain Neoplasms; Cancer Vaccines; Dogs; Glioma; Losartan; Propranolol; Prospective Studies; | 2022 |
Polyploid rat glioma cells. Production, oscillations of membrane potential and response to neurohormones.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenosine; Adrenergic beta-Agonists; | 1982 |
Turn on and turn off reactions of beta-adrenergic-sensitive adenylate cyclase in control and desensitized C6 glioma cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cell Line; Dihydroalprenolol; Enzyme Activatio | 1982 |
Blockade by neurotransmitter antagonists of veratridine-activated ion channels in neuronal cell lines.
Topics: Animals; Atropine; Calcium; Cell Line; Glioma; Guanidine; Guanidines; Hybrid Cells; Ion Channels; Ki | 1983 |
Desensitization of catecholamine-stimulated adenylate cyclase and down-regulation of beta-adrenergic receptors in rat glioma C6 cells. Role of cyclic AMP and protein synthesis.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Cell Line; Cell Membrane; Chol | 1984 |
Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dithiothreitol; Ethylmaleimide; Glioma; Isoproterenol; Kineti | 1980 |
Alteration in phospholipid methylation and impairment of signal transmission in persistently paramyxovirus-infected C6 rat glioma cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Enzyme Activation; Glioma; Membrane Lipids; Methylation; Phos | 1982 |
Phosphorylative modification of histone H1 subspecies following isoproterenol and N6,O2'-dibutyryl cyclic AMP stimulation of rat C6 glioma cells.
Topics: Amino Acids; Animals; Bucladesine; Cell Line; Cyclic AMP; Glioma; Histones; Isoproterenol; Neoplasms | 1982 |
Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cloning, Molecular; Enzyme Activation; Glioma; GTP-B | 1994 |
Lysophosphatidic acid reverts the beta-adrenergic agonist-induced morphological response in C6 rat glioma cells.
Topics: Adrenergic beta-Agonists; Aluminum; Animals; Blood Proteins; Dose-Response Relationship, Drug; Drug | 1993 |
Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Clonidin | 1993 |
Noradrenaline inhibits the programmed cell death induced by 1,25-dihydroxyvitamin D3 in glioma.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apoptosis; Brain Neoplasms; Calcitri | 1997 |
Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell.
Topics: Animals; Brain Neoplasms; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Glioma; Isoproterenol; | 1999 |
Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester.
Topics: Animals; Brain Neoplasms; Cell Compartmentation; Drug Interactions; Enzyme Activation; Enzyme Inhibi | 2000 |
In vivo labelling of beta-adrenergic receptors on rat glioma cells.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line; Glioma; Isoproterenol; Kinetics; Phentolamine; Pind | 1977 |
Desensitization of beta receptor mediated cyclic AMP response of cultured fibroblasts by partial agonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cells, Cultured; Cyclic AMP; Fibrobl | 1979 |
Quantitative relationship between beta-adrenergic receptor number and physiologic responses as studied with a long-lasting beta-adrenergic antagonist.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line; Cyclic AMP; Glioma; Guinea Pigs; Heart Atria; In Vi | 1979 |
Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*.
Topics: Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Ce | 1975 |
Measurements of adenosine 3':5'-cyclic monophosphate and membrane potential in neuroblastoma times glioma hybrid cells: opiates and adrenergic agonists cause effects opposite to those of prostaglandin E1.
Topics: Animals; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Glioma; Haloperidol; Hybrid Cells; Isoprotere | 1975 |
Catecholamine-induced cyclic AMP and morphologic alteration in glioma cells.
Topics: Animals; Bucladesine; Catecholamines; Cells, Cultured; Cyclic AMP; Glioma; Histamine; In Vitro Techn | 1975 |
Noradrenaline-refractoriness in cultured glioma cells.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cells, Cultured; Cyclic AMP; Glioma; Neoplasms, Experimental; | 1976 |
[Calcium current effects in the presence and absence of propranolol on cloned neuroblastoma and glioma hybrid cells].
Topics: Alprenolol; Animals; Calcium Channels; Cells, Cultured; Clone Cells; Glioma; Hybrid Cells; Mice; Neu | 1988 |
Stimulation of nerve growth factor mRNA content in C6 glioma cells by a beta-adrenergic receptor and by cyclic AMP.
Topics: Animals; Blotting, Northern; Cell Line; Colforsin; Cyclic AMP; Glioma; Isoproterenol; Molecular Weig | 1988 |
Chlorpromazine induces accumulation of inositol phosphates in C6 glioma cells.
Topics: Animals; Cell Line; Chlorpromazine; Desipramine; Glioma; Inositol; Inositol Phosphates; Lysophosphol | 1986 |
Modifications of phospholipid metabolism induced by chlorpromazine, desmethylimipramine and propranolol in C6 glioma cells.
Topics: Animals; Cell Line; Chlorpromazine; Desipramine; Diglycerides; Dose-Response Relationship, Drug; Gli | 1987 |
Cyclic AMP levels of C6 glioma cells treated with cis-dichlorodiammine platinum (cis-DDP).
Topics: Animals; Cell Line; Cells, Cultured; Cisplatin; Cyclic AMP; Glioma; Norepinephrine; Propranolol; Rat | 1987 |
Cyclic AMP-mediated induction of the cyclic AMP phosphodiesterase of C-6 glioma cells.
Topics: Animals; Bucladesine; Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Enzyme Induction; Glioma; | 1974 |
Biologically active catecholamines covalentyly bound to glass beads.
Topics: Animals; Catecholamines; Cell Line; Chick Embryo; Clone Cells; Culture Techniques; Cyclic AMP; Dogs; | 1972 |
Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.
Topics: Adenocarcinoma; Animals; Cell Line; Chromosomes; Clone Cells; Cyclic AMP; Electrophoresis, Starch Ge | 1973 |
Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.
Topics: Animals; Cell Fusion; Cell Line; Clone Cells; Cyclic AMP; Fibroblasts; Glioma; Hybrid Cells; Kinetic | 1974 |