propranolol has been researched along with Germinoblastoma in 22 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The beta-adrenergic agonist activity of the derivatives was evaluated in vitro by measuring the intracellular accumulation of cyclic AMP in S49 mouse lymphoma cells and by the displacement of iodocyanopindolol (ICYP)." | 3.67 | Conjugates of catecholamines. 6. Synthesis and beta-adrenergic activity of N-(hydroxyalkyl)catecholamine derivatives. ( Akita, Y; Avery, MA; Castagnoli, N; Goodman, M; Hoffman, BB; Melmon, KL; Reitz, AB; Rosenkranz, RP; Verlander, MS, 1985) |
| " The beta-adrenergic activities of these new compounds were assessed through measurement of intracellular cyclic AMP accumulation in S49 mouse lymphoma cells and displacement of iodocyanopindolol (ICYP) from membrane preparations." | 3.67 | Conjugates of catecholamines. 5. Synthesis and beta-adrenergic activity of N-(aminoalkyl)norepinephrine derivatives. ( Akita, Y; Castagnoli, N; Goodman, M; Hoffman, BB; Melmon, KL; Reitz, AB; Rosenkranz, RP; Sonveaux, E; Verlander, MS, 1985) |
| "The ability of the atypical agonists celiprolol and pindolol to induce sequestration and down regulation of beta adrenergic receptors was investigated in S49 lymphoma cells." | 3.67 | Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists. ( Molinoff, PB; Reynolds, EE, 1986) |
| " In the current studies, we show that several beta AR antagonists with ISA (dichloroisoproterenol, pindolol, and celiprolol) stimulate cAMP accumulation five-, two-, and threefold, respectively, in S49 lymphoma cells, but only if cells are simultaneously incubated with the diterpene forskolin." | 3.67 | Molecular mechanism of beta-adrenergic receptor blockers with intrinsic sympathomimetic activity. ( Insel, PA; Jasper, JR; Michel, MC, 1988) |
| "The radiolabeled agonist [3H]hydroxybenzylisoproterenol ([3H]HBI) and antagonist [125I]iodopindolol ([125I]IPIN) were used to investigate the properties of beta-adrenergic receptors on membranes prepared from L6 myoblasts and S49 lymphoma cells." | 3.67 | Properties of beta-adrenergic receptors of cultured mammalian cells. Interaction of receptors with a guanine nucleotide-binding protein in membranes prepared from L6 myoblasts and from wild-type and cyc- S49 lymphoma cells. ( Abramson, SN; Molinoff, PB, 1985) |
| "Treatment with propranolol slightly enhanced the proliferation of the RC-2A cells but did not markedly alter the growth rate of two other cell lines, regardless of their beta-adrenoceptor status." | 1.28 | Expression and function of beta-adrenergic receptors in human hematopoietic cell lines. ( Andersson, LC; Kontula, KK; Mäki, T, 1992) |
| " Ethanol also shifted the dose-response curve for stimulation of the enzyme by isoproterenol to the right." | 1.27 | Effects of ethanol in vitro on the beta adrenergic receptor-coupled adenylate cyclase system. ( Bode, DC; Molinoff, PB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maguire, ME | 2 |
| Erdos, JJ | 1 |
| Honeysett, JM | 1 |
| Insel, PA | 4 |
| Mahan, LC | 2 |
| Motulsky, HJ | 1 |
| Stoolman, LM | 1 |
| Koachman, AM | 1 |
| Jennings, AS | 1 |
| Saberi, M | 1 |
| Somkuti, SG | 1 |
| Hildebrandt, JD | 1 |
| Herberg, JT | 1 |
| Iyengar, R | 1 |
| Cremaschi, GA | 1 |
| Cazaux, CA | 1 |
| Miguel, S | 1 |
| Sterin-Borda, L | 1 |
| Ross, EM | 1 |
| Sturgill, TW | 1 |
| Biltonen, RL | 1 |
| Gilman, AG | 1 |
| Johnson, GL | 1 |
| Bourne, HR | 1 |
| Mäki, T | 1 |
| Andersson, LC | 1 |
| Kontula, KK | 1 |
| Leftheris, K | 1 |
| Goodman, M | 4 |
| Teshima, H | 1 |
| Sogawa, H | 1 |
| Kihara, H | 1 |
| Kubo, C | 1 |
| Mori, K | 1 |
| Nakagawa, T | 1 |
| Barber, DL | 1 |
| McGuire, ME | 1 |
| Ganz, MB | 1 |
| Bode, DC | 1 |
| Molinoff, PB | 3 |
| Reitz, AB | 2 |
| Avery, MA | 1 |
| Rosenkranz, RP | 2 |
| Verlander, MS | 3 |
| Melmon, KL | 3 |
| Hoffman, BB | 3 |
| Akita, Y | 2 |
| Castagnoli, N | 2 |
| Sonveaux, E | 1 |
| Reynolds, EE | 1 |
| Fabisiak, JP | 1 |
| Vesell, ES | 1 |
| Rannels, DE | 1 |
| Hughes, RJ | 1 |
| Jasper, JR | 1 |
| Michel, MC | 1 |
| Abramson, SN | 1 |
| Khan, MM | 1 |
| Marr-Leisy, D | 1 |
| Rosenkranz, R | 1 |
| Barber, R | 1 |
22 other studies available for propranolol and Germinoblastoma
| Article | Year |
|---|---|
Inhibition of magnesium uptake by beta-adrenergic agonists and prostaglandin E1 is not mediated by cyclic AMP.
Topics: Adrenergic beta-Antagonists; Animals; Biological Transport; Cell Line; Cholera Toxin; Cyclic AMP; Is | 1980 |
Inhibition of ornithine decarboxylase and S-adenosylmethionine decarboxylase activities of S49 lymphoma cells by agents increasing cyclic AMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosylmethionine Decarboxylase; Alprostadil; Bucla | 1981 |
Time-dependent decreases in binding affinity of agonists for beta-adrenergic receptors of intact S49 lymphoma cells. A mechanism of desensitization.
Topics: Animals; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP; Iodocyanopindolol; Isoprotereno | 1983 |
Thyroid lymphoma in a patient with hyperthyroidism.
Topics: Body Weight; Female; Humans; Hyperthyroidism; Lymphoma; Middle Aged; Propranolol; Propylthiouracil; | 1984 |
Divalent cation regulation of adenylyl cyclase. An allosteric site on the catalytic component.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Edetic Acid; Erythrocy | 1982 |
Reduced number and coupling of beta-adrenergic receptors in a modified S49 mouse lymphoma cell line.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cyclic AMP; GTP-Binding Proteins; Lymphoma; Mice; Propranol | 1994 |
Relationship between the beta-adrenergic receptor and adenylate cyclase.
Topics: Adenylyl Cyclases; Bacterial Toxins; Cell Line; Cell Membrane; Enzyme Activation; Guanosine Triphosp | 1977 |
Influence of cholera toxin on the regulation of adenylate cyclase by GTP.
Topics: Adenylyl Cyclases; Binding Sites; Cell Line; Cell Membrane; Cholera Toxin; Cyclic AMP; Enzyme Activa | 1977 |
Expression and function of beta-adrenergic receptors in human hematopoietic cell lines.
Topics: Blood Cells; Blotting, Southern; Cell Division; Cell Line; Cyclic AMP; DNA; DNA, Neoplasm; Humans; I | 1992 |
Synthesis and beta-adrenergic antagonist activity of stereoisomeric practolol and propranolol derivatives.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Animals; Biological Assay; Chemical Phenomena; Chemistr | 1990 |
Prevention of immunosuppression in stressed mice by neurotropin(NSP).
Topics: Animals; Atropine; Body Weight; Cytotoxicity, Immunologic; Diazepam; Female; Immune Tolerance; Kille | 1990 |
Beta-adrenergic and somatostatin receptors regulate Na-H exchange independent of cAMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bucladesine; Cell Line; Cells, Cultured; | 1989 |
Effects of ethanol in vitro on the beta adrenergic receptor-coupled adenylate cyclase system.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dose-Response Relationship, Drug; Ethanol; GTP-Binding Protei | 1988 |
Conjugates of catecholamines. 6. Synthesis and beta-adrenergic activity of N-(hydroxyalkyl)catecholamine derivatives.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Catecholamines; Cyclic AMP; Hydroxylation; | 1985 |
Conjugates of catecholamines. 5. Synthesis and beta-adrenergic activity of N-(aminoalkyl)norepinephrine derivatives.
Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Cyclic AMP; In Vitro Techniques; Iodocyanop | 1985 |
Down regulation of beta adrenergic receptors in S49 lymphoma cells induced by atypical agonists.
Topics: Adrenergic beta-Agonists; Animals; Binding Sites; Celiprolol; Cell Division; Cell Line; Isoprotereno | 1986 |
Interactions of beta adrenergic antagonists with isolated rat alveolar type II pneumocytes. II. Receptor-independent accumulation of beta adrenergic antagonists and other cationic amphiphilic drugs in lamellar bodies.
Topics: Adrenergic beta-Antagonists; Animals; Histocytochemistry; Humans; Hydrogen-Ion Concentration; Iodocy | 1987 |
Certain beta-blockers can decrease beta-adrenergic receptor number: II. Down-regulation of receptor number by alprenolol and propranolol in cultured lymphoma and muscle cells.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cell Line; Cyclic AMP; Humans; Lymphoma; Muscles; | 1988 |
Molecular mechanism of beta-adrenergic receptor blockers with intrinsic sympathomimetic activity.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Celiprolol; Colforsin; Cyclic AMP; Drug Synergism; I | 1988 |
Properties of beta-adrenergic receptors of cultured mammalian cells. Interaction of receptors with a guanine nucleotide-binding protein in membranes prepared from L6 myoblasts and from wild-type and cyc- S49 lymphoma cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; GTP-Binding Proteins; Isoproterenol; Kinetics; | 1985 |
In vitro pharmacologic activity of congener derivatives and model conjugates of propranolol and practolol.
Topics: Adipose Tissue; Animals; Cell Line; Chemical Phenomena; Chemistry; Cyclic AMP; Lung; Lymphoma; Male; | 1987 |
Forskolin binding to intact S49 lymphoma cells.
Topics: Animals; Binding, Competitive; Colforsin; Cytochalasin B; Epinephrine; Isoproterenol; Ligands; Lymph | 1988 |