Page last updated: 2024-11-03

propranolol and Genetic Predisposition

propranolol has been researched along with Genetic Predisposition in 14 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"A young man was diagnosed with hyperthyroidism 10 years prior to current presentation after a random health screening revealed an elevated free thyroxine (fT4) of 36."4.89Elevated free thyroxine and non-suppressed thyrotropin. ( Deepak, DS; Loh, TP; Mok, SF; Venkatesh, B, 2013)
" These mice have atrial tachycardia and increased susceptibility to aconitine-induced arrhythmia."3.72Changes underlying arrhythmia in the transgenic heart overexpressing Refsum disease gene-associated protein. ( Ahn, YK; Baik, YH; Jeong, BC; Kim, JH; Kim, KK; Koh, JT; Lee, HS, 2004)
"Holter monitoring revealed ectopic atrial tachycardia during tachyarrhythmia and occasional sinus pauses with junctional escape beats."2.61Severe congenital RYR1-associated myopathy complicated with atrial tachycardia and sinus node dysfunction: a case report. ( Abe, Y; Hayakawa, I; Kubota, M; Ono, H, 2019)
"Dogs with an inherited predisposition to sudden death display ventricular arrhythmias having certain characteristics, such as pause dependence, that are suggestive of early afterdepolarization-induced triggered activity."1.29Phenylephrine-induced ventricular arrhythmias in dogs with inherited sudden death. ( Brittain, D; Flahive, WJ; Gilmour, RF; Lee, RJ; Lewis, BA; Moïse, NS; Moon, PF; Pride, HP; Zipes, DP, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's9 (64.29)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayakawa, I1
Abe, Y1
Ono, H1
Kubota, M1
Deuschl, G1
Berg, D1
Mok, SF1
Loh, TP1
Venkatesh, B1
Deepak, DS1
Wang, DW1
Crotti, L1
Shimizu, W1
Pedrazzini, M1
Cantu, F1
De Filippo, P1
Kishiki, K1
Miyazaki, A1
Ikeda, T1
Schwartz, PJ1
George, AL1
Barski, L1
Nevzorov, R1
Lotkowitz, A1
Shleyfer, E1
Liel, Y1
Sangla, S1
Tranchant, C1
Hofman, N1
Tan, HL1
Alders, M1
van Langen, IM1
Wilde, AA1
Koh, JT1
Jeong, BC1
Kim, JH1
Ahn, YK1
Lee, HS1
Baik, YH1
Kim, KK1
Lionet, A1
Barsumau, J1
Azar, R1
Zein, EF1
Karaa, SE1
Megarbane, A1
Moïse, NS1
Moon, PF1
Flahive, WJ1
Brittain, D1
Pride, HP1
Lewis, BA1
Zipes, DP1
Lee, RJ1
Gilmour, RF1
Nurnberger, JI1
Adkins, S1
Lahiri, DK1
Mayeda, A1
Hu, K1
Lewy, A1
Miller, A1
Bowman, ES1
Miller, MJ1
Rau, L1
Smiley, C1
Davis-Singh, D1
Masuhr, F1
Wissel, J1
Müller, J1
Scholz, U1
Poewe, W1
Shusterman, V1
Usiene, I1
Harrigal, C1
Lee, JS1
Kubota, T1
Feldman, AM1
London, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives[NCT04832126]100 participants (Anticipated)Observational2018-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for propranolol and Genetic Predisposition

ArticleYear
Severe congenital RYR1-associated myopathy complicated with atrial tachycardia and sinus node dysfunction: a case report.
    Italian journal of pediatrics, 2019, Dec-19, Volume: 45, Issue:1

    Topics: Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Genetic Predisposit

2019
[Essential tremor: state of the art].
    Der Nervenarzt, 2018, Volume: 89, Issue:4

    Topics: Age Factors; Deep Brain Stimulation; Diagnosis, Differential; Essential Tremor; Genetic Predispositi

2018
Elevated free thyroxine and non-suppressed thyrotropin.
    BMJ case reports, 2013, Oct-28, Volume: 2013

    Topics: Adult; Carbimazole; Drug Resistance; Follow-Up Studies; Genetic Predisposition to Disease; Humans; H

2013
[Writer's cramp].
    Revue neurologique, 2009, Volume: 165 Spec No 3

    Topics: Botulinum Toxins, Type A; Clonazepam; Combined Modality Therapy; Cumulative Trauma Disorders; Diagno

2009

Other Studies

10 other studies available for propranolol and Genetic Predisposition

ArticleYear
Malignant perinatal variant of long-QT syndrome caused by a profoundly dysfunctional cardiac sodium channel.
    Circulation. Arrhythmia and electrophysiology, 2008, Volume: 1, Issue:5

    Topics: Action Potentials; Anti-Arrhythmia Agents; DNA Mutational Analysis; Dose-Response Relationship, Drug

2008
Thyrotoxic hypokalemic periodic paralysis as the presenting symptom in a young Ashkenazi Jewish man.
    The Israel Medical Association journal : IMAJ, 2009, Volume: 11, Issue:9

    Topics: Adult; Antihypertensive Agents; Antithyroid Agents; Emergencies; Follow-Up Studies; Genetic Predispo

2009
Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment?
    Journal of the American College of Cardiology, 2010, Jun-08, Volume: 55, Issue:23

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cause of Death; Chi-Square Distribution;

2010
Changes underlying arrhythmia in the transgenic heart overexpressing Refsum disease gene-associated protein.
    Biochemical and biophysical research communications, 2004, Jan-02, Volume: 313, Issue:1

    Topics: Aconitine; Action Potentials; Animals; Arrhythmias, Cardiac; Blood Pressure; Carrier Proteins; Femal

2004
[Thyrotoxic hypokalaemic periodic paralysis in a Caucasian male].
    Nephrologie, 2004, Volume: 25, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Asian People; Carbimazole; Genetic Predispos

2004
Familial occurrence of painful subacute thyroiditis associated with human leukocyte antigen-B35.
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:5 Pt 1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Anti-Inflammator

2007
Phenylephrine-induced ventricular arrhythmias in dogs with inherited sudden death.
    Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:3

    Topics: Animals; Atropine; Cardiac Pacing, Artificial; Death, Sudden; Dogs; Female; Genetic Predisposition t

1996
Melatonin suppression by light in euthymic bipolar and unipolar patients.
    Archives of general psychiatry, 2000, Volume: 57, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female;

2000
Quantification of sensory trick impact on tremor amplitude and frequency in 60 patients with head tremor.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anticonvulsants; Central Nervous System

2000
Strain-specific patterns of autonomic nervous system activity and heart failure susceptibility in mice.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atropi

2002