propranolol has been researched along with Gastric Diseases in 19 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months." | 9.11 | Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005) |
| "We conducted a prospective, multicenter, randomized trial to compare the efficacy of sclerotherapy plus propranolol with that of propranolol alone in the prevention of recurrent gastroesophageal bleeding in severely cirrhotic patients." | 9.07 | Does elective sclerotherapy improve the efficacy of long-term propranolol for prevention of recurrent bleeding in patients with severe cirrhosis? A prospective multicenter, randomized trial. ( Anciaux, ML; Ink, O; Labadie, H; Lenoir, C; Marill, JL; Martin, T; Masliah, C; Perrin, D; Poynard, T; Reville, M, 1992) |
| "In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months." | 5.11 | Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005) |
| "Band ligation of esophageal varices may accentuate gastropathy, which in this study was partly relieved by propranolol." | 5.09 | The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial. ( Chen, TA; Cheng, JS; Chiang, HT; Hsu, PI; Lai, KH; Lin, CK; Lo, GH; Wang, EM, 2001) |
| "We conducted a prospective, multicenter, randomized trial to compare the efficacy of sclerotherapy plus propranolol with that of propranolol alone in the prevention of recurrent gastroesophageal bleeding in severely cirrhotic patients." | 5.07 | Does elective sclerotherapy improve the efficacy of long-term propranolol for prevention of recurrent bleeding in patients with severe cirrhosis? A prospective multicenter, randomized trial. ( Anciaux, ML; Ink, O; Labadie, H; Lenoir, C; Marill, JL; Martin, T; Masliah, C; Perrin, D; Poynard, T; Reville, M, 1992) |
| "The aim of this study was to describe the results of endoscopic secondary prophylaxis, alone or in combination with propranolol, used to prevent upper gastrointestinal bleeding (UGIB) in children and adolescents with esophageal varices." | 3.79 | Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices. ( Bittencourt, PF; Carvalho, SD; dos Santos, JM; Fagundes, ED; Ferreira, AP; Ferreira, AR; Ferreira, LS; Figueiredo Filho, PP; Magalhães, MC; Penna, FJ, 2013) |
| "Propranolol-treated patients had fewer episodes of acute bleeding than controls (0." | 2.67 | Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis. ( Bosch, J; González, A; Panés, J; Pérez, R; Pérez-Ayuso, RM; Piqué, JM; Quintero, E; Rigau, J; Valderrama, R; Viver, J, 1991) |
| "A minimum of three migraine attacks were treated during each treatment period." | 2.67 | Propranolol in the treatment of acute migraine attacks. ( Banerjee, M; Findley, L, 1991) |
| "N-Ethylmaleimide was administered in doses that previously had been shown to increase gastric vascular permeability (10 mg/kg) or inhibit gastric mucosal sulfhydryl compounds (50 mg/kg)." | 1.28 | Intragastric nicotine protects against 40% ethanol-induced gastric mucosal injury despite pretreatment with propranolol or N-ethylmaleimide in rats. ( Endoh, K; Leung, FW; Ro, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| dos Santos, JM | 1 |
| Ferreira, AR | 1 |
| Fagundes, ED | 1 |
| Ferreira, AP | 1 |
| Ferreira, LS | 1 |
| Magalhães, MC | 1 |
| Bittencourt, PF | 1 |
| Carvalho, SD | 1 |
| Figueiredo Filho, PP | 1 |
| Penna, FJ | 1 |
| Hsu, DZ | 1 |
| Wang, ST | 1 |
| Deng, JF | 1 |
| Liu, MY | 1 |
| Jutabha, R | 1 |
| Jensen, DM | 1 |
| Martin, P | 1 |
| Savides, T | 1 |
| Han, SH | 1 |
| Gornbein, J | 1 |
| Lebrec, D | 1 |
| Poynard, T | 2 |
| Hillon, P | 1 |
| Benhamou, JP | 1 |
| Shigemori, H | 1 |
| Iwao, T | 1 |
| Ikegami, M | 1 |
| Toyonaga, A | 1 |
| Tanikawa, K | 1 |
| Panés, J | 2 |
| Bordas, JM | 1 |
| Piqué, JM | 3 |
| García-Pagán, JC | 1 |
| Feu, F | 1 |
| Terés, J | 1 |
| Bosch, J | 2 |
| Rodés, J | 1 |
| Rataboli, PV | 2 |
| Diniz D'Souza, RS | 1 |
| Dhume, VG | 2 |
| Payen, JL | 1 |
| Cales, P | 1 |
| Pienkowski, P | 1 |
| Sozzani, P | 1 |
| Kervran, A | 1 |
| Frexinos, J | 1 |
| Pascal, JP | 1 |
| Hermann, R | 1 |
| Lo, GH | 1 |
| Lai, KH | 1 |
| Cheng, JS | 1 |
| Hsu, PI | 1 |
| Chen, TA | 1 |
| Wang, EM | 1 |
| Lin, CK | 1 |
| Chiang, HT | 1 |
| Abasov, IT | 1 |
| Iof, IM | 1 |
| Ink, O | 1 |
| Martin, T | 1 |
| Reville, M | 1 |
| Anciaux, ML | 1 |
| Lenoir, C | 1 |
| Marill, JL | 1 |
| Labadie, H | 1 |
| Masliah, C | 1 |
| Perrin, D | 1 |
| Bhandare, PN | 1 |
| D'Souza, RS | 1 |
| Pérez-Ayuso, RM | 2 |
| González, A | 1 |
| Pérez, R | 1 |
| Rigau, J | 1 |
| Quintero, E | 1 |
| Valderrama, R | 1 |
| Viver, J | 1 |
| Endoh, K | 1 |
| Ro, G | 1 |
| Leung, FW | 1 |
| Banerjee, M | 1 |
| Findley, L | 1 |
| Hüppe, D | 1 |
| May, B | 1 |
| Geoffroy, P | 1 |
| Duchateau, A | 1 |
| Thiéfin, G | 1 |
| Zeitoun, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Capsule Endoscopy Accurate and Cost-effective Enough to Screen Cirrhotic Patients for Varices & Other Lesions?[NCT01079416] | 65 participants (Actual) | Observational | 2006-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Gastric Diseases
| Article | Year |
|---|---|
[Gastropathy due to portal hypertension].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diagnosis, Differential; Gastritis | 1997 |
Portal hypertensive gastropathy.
Topics: Animals; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; | 1991 |
9 trials available for propranolol and Gastric Diseases
| Article | Year |
|---|---|
Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices.
Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu | 2005 |
Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; | 1981 |
Effects of propranolol on gastric mucosal perfusion and serum gastrin level in cirrhotic patients with portal hypertensive gastropathy.
Topics: Double-Blind Method; Female; Gastric Mucosa; Gastrins; Gastrointestinal Hemorrhage; Humans; Hyperten | 1994 |
Effects of propranolol on gastric mucosal perfusion in cirrhotic patients with portal hypertensive gastropathy.
Topics: Female; Gastric Mucosa; Hemodynamics; Humans; Hypertension, Portal; Injections, Intravenous; Laser-D | 1993 |
Weakness of mucosal barrier in portal hypertensive gastropathy of alcoholic cirrhosis. Effects of propranolol and enprostil.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anti-Ulcer Agents; Aspirin; Dinoprostone; Enprostil; Femal | 1995 |
The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial.
Topics: Adult; Aged; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; | 2001 |
Does elective sclerotherapy improve the efficacy of long-term propranolol for prevention of recurrent bleeding in patients with severe cirrhosis? A prospective multicenter, randomized trial.
Topics: Esophageal Diseases; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Liv | 1992 |
Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis.
Topics: Actuarial Analysis; Acute Disease; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up | 1991 |
Propranolol in the treatment of acute migraine attacks.
Topics: Acute Disease; Adult; Aged; Double-Blind Method; Humans; Middle Aged; Migraine Disorders; Propranolo | 1991 |
8 other studies available for propranolol and Gastric Diseases
| Article | Year |
|---|---|
Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices.
Topics: Adolescent; Adrenergic beta-Antagonists; Child; Child, Preschool; Endoscopy, Gastrointestinal; Esoph | 2013 |
Epinephrine protects against severe acute gastric bleeding in rats: role of nitric oxide and glutathione.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Enzyme Inhibitors; Epinephrine; Gastric Mucosa; | 2005 |
Effect of antihypertensive drugs on ethanol induced gastric lesions: is there a correlation with mucosal blood flow?
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Ethanol; Gastric Mucosa; Gastro | 1993 |
Application of intragastric pH-metry for diagnostic and therapeutic control of gastric diseases.
Topics: Adult; Atropine; Duodenal Ulcer; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Hista | 1977 |
Protective effect of propranolol on ethanol-induced gastric lesions in rats: probable mechanism of action.
Topics: Animals; Drug Interactions; Ethanol; Gastric Fundus; Gastrointestinal Hemorrhage; Indomethacin; Lido | 1992 |
Intragastric nicotine protects against 40% ethanol-induced gastric mucosal injury despite pretreatment with propranolol or N-ethylmaleimide in rats.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Gastric Mucosa; Male; Nicotine; | 1992 |
[Propranolol in portal hypertensive gastropathy].
Topics: Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Liver Cirrhosis; Propranolol; Stomach Dis | 1991 |
Effects of propranolol and sucralfate on ethanol-induced gastric mucosal damage in chronic portal hypertensive rats.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Hypertension, Portal; Male; Prop | 1987 |