propranolol has been researched along with Experimental Neoplasms in 34 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 7.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
| "Propranolol treatment produced slight and similar effects in both normal and tumour-bearing rats." | 5.26 | Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma. ( Debreczeni, LA; Farsang, C; Takács, L, 1980) |
| " One week after starting propranolol treatment, all rats were submitted to chemical induction of oral carcinogenesis with 4-nitroquinoline-1-oxide (4NQO)." | 3.96 | Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion. ( Bernabé, DG; Biasoli, ÉR; Cecilio, HP; Furuse, C; Kayahara, GM; Miyahara, GI; Oliveira, SHP; Pereira, KM; Valente, VB, 2020) |
| "The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)." | 3.66 | Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980) |
| " The widespread and chronic use of these drugs has generated a concern for their potential chronic toxicity." | 2.37 | A toxicological review of beta-adrenergic blockers. ( Fishbein, L; Jackson, CD, 1986) |
| " Pharmacokinetic experiments show oral bioavailability through gastric absorption." | 1.48 | Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization. ( Cescon, DW; Hansen, MD; Hoj, JP; Siddiqui-Jain, A, 2018) |
| " The objective of this study was to investigate the effects of dosing protocol on the distribution of propranolol in the periocular tissues and plasma after topical ocular instillation." | 1.42 | Effects of dosing protocol on distribution of propranolol in periocular tissues after topical ocular instillation. ( Hao, J; Li, SK; Liu, H; Yang, MB, 2015) |
| "Propranolol treatment produced slight and similar effects in both normal and tumour-bearing rats." | 1.26 | Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma. ( Debreczeni, LA; Farsang, C; Takács, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (73.53) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, XL | 1 |
| Yang, YR | 1 |
| Mo, XF | 1 |
| Wei, JL | 1 |
| Zhang, XJ | 1 |
| You, QD | 1 |
| Siddiqui-Jain, A | 1 |
| Hoj, JP | 1 |
| Cescon, DW | 1 |
| Hansen, MD | 1 |
| Vesci, L | 1 |
| Milazzo, FM | 1 |
| Stasi, MA | 1 |
| Pace, S | 1 |
| Manera, F | 1 |
| Tallarico, C | 1 |
| Cini, E | 1 |
| Petricci, E | 1 |
| Manetti, F | 1 |
| De Santis, R | 1 |
| Giannini, G | 1 |
| Daher, C | 1 |
| Vimeux, L | 1 |
| Stoeva, R | 1 |
| Peranzoni, E | 1 |
| Bismuth, G | 1 |
| Wieduwild, E | 1 |
| Lucas, B | 1 |
| Donnadieu, E | 1 |
| Bercovici, N | 1 |
| Trautmann, A | 1 |
| Feuillet, V | 1 |
| Cecilio, HP | 1 |
| Valente, VB | 1 |
| Pereira, KM | 1 |
| Kayahara, GM | 1 |
| Furuse, C | 1 |
| Biasoli, ÉR | 1 |
| Miyahara, GI | 1 |
| Oliveira, SHP | 1 |
| Bernabé, DG | 1 |
| Liao, X | 1 |
| Chaudhary, P | 1 |
| Qiu, G | 1 |
| Che, X | 1 |
| Fan, L | 1 |
| Liu, H | 1 |
| Yang, MB | 1 |
| Li, SK | 1 |
| Hao, J | 1 |
| TUCKER, MJ | 1 |
| ALCOCK, SJ | 1 |
| BAKER, SB | 1 |
| Heumann, R | 1 |
| Reiser, G | 2 |
| Van Calker, D | 1 |
| Hamprecht, B | 3 |
| Balitskiĭ, KP | 1 |
| Gozlan, H | 1 |
| Homburger, V | 1 |
| Lucas, M | 1 |
| Bockaert, J | 1 |
| Michelot, R | 1 |
| Harrison, JJ | 1 |
| Schwoch, G | 1 |
| Schweppe, JS | 1 |
| Jungmann, RA | 1 |
| Reisine, TD | 1 |
| Heisler, S | 1 |
| Hook, VY | 1 |
| Axelrod, J | 1 |
| Debreczeni, LA | 2 |
| Farsang, C | 2 |
| Takács, L | 2 |
| Devor, M | 1 |
| Jänig, W | 1 |
| Brooks, SL | 1 |
| Neville, AM | 1 |
| Rothwell, NJ | 1 |
| Stock, MJ | 1 |
| Wilson, S | 1 |
| Feyns, LV | 1 |
| Beisler, JA | 1 |
| Driscoll, JS | 1 |
| Adamson, RA | 1 |
| Gurkalo, VK | 1 |
| Zabezhinskiĭ, MA | 1 |
| Doore, BJ | 1 |
| Bashor, MM | 1 |
| Spitzer, N | 1 |
| Mawe, RC | 1 |
| Saier, MH | 1 |
| Traber, J | 2 |
| Fischer, K | 2 |
| Oey, J | 1 |
| Okamura, N | 1 |
| Terayama, H | 1 |
| Boyd, H | 2 |
| Martin, TJ | 2 |
| Villeneuve, JP | 1 |
| Gerber, JG | 1 |
| Branch, RA | 1 |
| Shand, DG | 1 |
| Wilson, JT | 1 |
| Peters, CE | 2 |
| Chaplin, DJ | 2 |
| Horsman, MR | 1 |
| Trotter, MJ | 1 |
| Jackson, CD | 1 |
| Fishbein, L | 1 |
| Muskhelishvili, LV | 1 |
| Sharashidze, LK | 1 |
| Gersamiia, GK | 1 |
| Gedevanishvili, MD | 1 |
| Schorr, I | 1 |
| Rathnam, P | 1 |
| Saxena, BB | 1 |
| Ney, RL | 1 |
| Louis, CJ | 1 |
| Latzin, S | 1 |
| Howe, R | 1 |
| Malarkey, WB | 1 |
| Daughaday, WH | 1 |
1 review available for propranolol and Experimental Neoplasms
| Article | Year |
|---|---|
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolami | 1986 |
33 other studies available for propranolol and Experimental Neoplasms
| Article | Year |
|---|---|
Design, synthesis, and evaluation of benzofuran derivatives as novel anti-pancreatic carcinoma agents via interfering the hypoxia environment by targeting HIF-1α pathway.
Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Proliferation; Dose-Response Relationship, Drug; D | 2017 |
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.
Topics: Amides; Animals; Cell Line, Tumor; Cell Proliferation; Dogs; Dose-Response Relationship, Drug; Human | 2018 |
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dos | 2018 |
Blockade of β-Adrenergic Receptors Improves CD8
Topics: Adrenergic beta-Antagonists; Animals; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cells, Cultured; | 2019 |
Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion.
Topics: 4-Nitroquinoline-1-oxide; Adrenergic beta-Antagonists; Animals; Carcinogenesis; Carcinogens; Cytokin | 2020 |
The role of propranolol as a radiosensitizer in gastric cancer treatment.
Topics: Animals; Disease Models, Animal; Humans; Male; Mice, Nude; Neoplasms, Experimental; Propranolol; Rad | 2018 |
Effects of dosing protocol on distribution of propranolol in periocular tissues after topical ocular instillation.
Topics: Adrenergic beta-Antagonists; Animals; Chromatography, Liquid; Dose-Response Relationship, Drug; Eye | 2015 |
ABSENCE OF CARCINOGENIC PROPERTIES OF PROPRANOLOL IN MICE.
Topics: Animals; Carcinogens; Neoplasms; Neoplasms, Experimental; Pharmacology; Propranolol; Research; Sympa | 1965 |
Polyploid rat glioma cells. Production, oscillations of membrane potential and response to neurohormones.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenosine; Adrenergic beta-Agonists; | 1982 |
[Methods of directly influencing the metastatic process].
Topics: Animals; Growth Inhibitors; Interferons; Isoproterenol; Macrophages; Mice; Mice, Inbred Strains; Neo | 1984 |
Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol.
Topics: Adenylyl Cyclases; Animals; Cell Line; Dithiothreitol; Ethylmaleimide; Glioma; Isoproterenol; Kineti | 1980 |
Phosphorylative modification of histone H1 subspecies following isoproterenol and N6,O2'-dibutyryl cyclic AMP stimulation of rat C6 glioma cells.
Topics: Amino Acids; Animals; Bucladesine; Cell Line; Cyclic AMP; Glioma; Histones; Isoproterenol; Neoplasms | 1982 |
Activation of beta 2-adrenergic receptors on mouse anterior pituitary tumor cells increases cyclic adenosine 3':5'-monophosphate synthesis and adrenocorticotropin release.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line; Cell Membrane; Cyclic AMP; Dihydroalprenolol; Epine | 1983 |
Effect of phenoxybenzamine, propranolol, phenylephrine and isoproterenol on the circulation of rats bearing Guérin carcinoma.
Topics: Animals; Axilla; Blood Circulation; Blood Pressure; Carcinoma; Cardiac Output; Humans; Hyperkinesis; | 1980 |
Activation of myelinated afferents ending in a neuroma by stimulation of the sympathetic supply in the rat.
Topics: Afferent Pathways; Animals; Axons; Electric Conductivity; Electric Stimulation; Epinephrine; Female; | 1981 |
Sympathetic activation of brown-adipose-tissue thermogenesis in cachexia.
Topics: Adipose Tissue, Brown; Animals; Cachexia; Female; Guanine Nucleotides; Guanosine Diphosphate; Mice; | 1981 |
Synthesis of propranolol mustard as a possible lung-specific antitumor agent.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Lung Neoplasms; Mice; Neoplasms, Expe | 1980 |
[Modification of chemical carcinogenesis with adrenergic compounds].
Topics: Adrenergic alpha-Antagonists; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Drug Ant | 1978 |
Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*.
Topics: Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Ce | 1975 |
Measurements of adenosine 3':5'-cyclic monophosphate and membrane potential in neuroblastoma times glioma hybrid cells: opiates and adrenergic agonists cause effects opposite to those of prostaglandin E1.
Topics: Animals; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Glioma; Haloperidol; Hybrid Cells; Isoprotere | 1975 |
Noradrenaline-refractoriness in cultured glioma cells.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cells, Cultured; Cyclic AMP; Glioma; Neoplasms, Experimental; | 1976 |
Comparison of the epinephrine-mediated activation of adenylate cyclase in plasma membranes from liver and ascites hepatomas of rats.
Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Cell Membrane; Enzyme Activation; Epinephrine | 1976 |
The effect of propranolol on induction of rat liver tumors by a chemical carcinogen.
Topics: Animals; Diet; Drug Interactions; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, E | 1977 |
Drug metabolism in rats bearing a pituitary mammotropic tumor.
Topics: Aminopyrine; Animals; Antipyrine; Cardiac Output; Half-Life; Liver; Male; Mammary Glands, Animal; Ne | 1979 |
Regional vascular reactivity in rats with Guérin carcinoma (GC).
Topics: Animals; Blood Pressure; Carcinoma; Cardiac Output; Isoproterenol; Male; Neoplasms, Experimental; Ph | 1979 |
Blood flow modification in the SCCVII tumor: effects of 5-hydroxytryptamine, hydralazine, and propranolol.
Topics: Animals; Blood Flow Velocity; Cell Survival; Erythrocytes; Hydralazine; Injections, Intraperitoneal; | 1992 |
Drug induced perturbations in tumor blood flow: therapeutic potential and possible limitations.
Topics: Animals; Cell Hypoxia; Hydralazine; Mice; Neoplasms, Experimental; Niacinamide; Propranolol; Regiona | 1991 |
[Decreased isoproterenol sensitivity of the salivary epithelium in mice with transplanted tumors].
Topics: Adenylyl Cyclases; Animals; Cell Division; Drug Resistance; Epithelium; Isoproterenol; Male; Mice; N | 1986 |
Multiple specific hormone receptors in the adenylate cyclase of an adrenocortical carcinoma.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotro | 1971 |
Activity and hormone responsiveness of adenyl cyclase during induction of tumors in rat liver with 3'-methyl-4-dimethylaminoazobenzene.
Topics: Adenylyl Cyclases; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Diet; Enzyme Activation; | 1974 |
Morphine antagonizes the action of prostaglandin in neuroblastoma cells but not of prostaglandin and noradrenaline in glioma and glioma times fibroblast hybrid cells.
Topics: Animals; Cell Fusion; Cell Line; Clone Cells; Cyclic AMP; Fibroblasts; Glioma; Hybrid Cells; Kinetic | 1974 |
Carcinogenicity of "Alderlin" (pronethalol) in mice.
Topics: Animals; Azirines; Carcinogens; Chemistry, Pharmaceutical; Ethanolamines; Mice; Neoplasms, Experimen | 1965 |
The influence of levodopa and adrenergic blockade on growth hormone and prolactin secretion in the MStTW15 tumor bearing rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Depression, Chemical; Dihydroxyp | 1972 |