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propranolol and Experimental Hepatoma

propranolol has been researched along with Experimental Hepatoma in 11 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"Propranolol is a lipophilic non-selective beta-blocker mainly eliminated via the liver; atenolol is a hydrophilic beta 1-selective blocking agent, mainly eliminated via the kidney."1.29Evaluation of the tumor-promoting activity of two beta-adrenoreceptor blocking agents, propranolol and atenolol, in liver of Fischer 344 rats. ( Ameri, L; Arias, E; Girotti, P; Mazzoleni, G; Presta, M; Radaelli, G; Ragnotti, G; Zavanella, T, 1994)
" Vasoactive drugs may therefore be of value to diminish adverse side effects of the combination cytostatic agent + DSM, probably decreasing overspill into normal tissues."1.28Reduction by norepinephrine of the side effects induced by combined hepatic arterial administration of degradable strach microspheres and adriamycin in rats with a liver adenocarcinoma. ( Jakobsson, B; Roos, G; Stenram, U; Teder, H, 1991)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsunaga, T2
Takemoto, N1
Miyamoto, K2
Koshiura, R2
Iwasaki, M1
Presta, M2
Zavanella, T2
Mazzocchi, C1
Ziliani, S1
Mazzoleni, G2
Calovini, D1
Braga, M1
Ragnotti, G2
Ackerman, NB2
Makohon, S1
Ming, M1
Wu, J1
Lachance, S1
Delalandre, A1
Carrière, S1
Chan, JS1
Radaelli, G1
Girotti, P1
Arias, E1
Ameri, L1
Steiner, A1
Walle, T1
Jakobsson, B1
Teder, H1
Roos, G1
Stenram, U1
Cortinovis, C1
Mayer, D1
Bouscarel, B1
Paris, H1
Murat, JC1
Jacobs, R1
Bloom, ND1
Poon, TT1
Burton, MA1
Gray, BN1

Other Studies

11 other studies available for propranolol and Experimental Hepatoma

ArticleYear
Studies on responsiveness of hepatoma cells to catecholamines. I. Lack of beta-adrenergic responsiveness in rat ascites hepatoma AH13 cells.
    Japanese journal of pharmacology, 1984, Volume: 36, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Binding Sites; Catecholamines; Cell

1984
Relationship between enhancement of cytotoxic effect of mitomycin C and increase of intracellular cyclic adenosine 3':5'-monophosphate by isoproterenol in rat ascites hepatoma cells.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:1

    Topics: Animals; Bucladesine; Cell Survival; Cells, Cultured; Cyclic AMP; Female; Isoproterenol; Liver Neopl

1983
Thyroid and chemical hepatocarcinogenesis: further insights from the hepatocarcinogen ZAMI 1305.
    Toxicologic pathology, 1984, Volume: 12, Issue:1

    Topics: Animals; Carcinogens; Female; Hyperplasia; Liver Neoplasms, Experimental; Male; Organ Size; Propanol

1984
The blood supply of experimental liver metastases. VII. Further studies on increased tumor vascularity caused by epinephrine.
    Microcirculation, endothelium, and lymphatics, 1984, Volume: 1, Issue:5

    Topics: Animals; Carcinoma 256, Walker; Epinephrine; Liver Neoplasms; Liver Neoplasms, Experimental; Microci

1984
Beta-adrenergic receptors and angiotensinogen gene expression in mouse hepatoma cells in vitro.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:1

    Topics: Angiotensin II; Angiotensinogen; Animals; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Gene

1995
Evaluation of the tumor-promoting activity of two beta-adrenoreceptor blocking agents, propranolol and atenolol, in liver of Fischer 344 rats.
    Carcinogenesis, 1994, Volume: 15, Issue:11

    Topics: Animals; Atenolol; Body Weight; Carcinogens; Diethylnitrosamine; Female; gamma-Glutamyltransferase;

1994
Potent inhibition of MAO mediated propranolol metabolism by dimethyl sulfoxide in Hep G2 cells.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Hum

1992
Reduction by norepinephrine of the side effects induced by combined hepatic arterial administration of degradable strach microspheres and adriamycin in rats with a liver adenocarcinoma.
    Selective cancer therapeutics, 1991,Fall, Volume: 7, Issue:3

    Topics: Adenocarcinoma; Animals; Doxorubicin; Hepatic Artery; Injections, Intra-Arterial; Liver; Liver Neopl

1991
Study of beta-adrenoceptors and beta-adrenergic responsiveness in cultured "preneoplastic-like" and neoplastic rat hepatocytes.
    General pharmacology, 1985, Volume: 16, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Binding, Com

1985
Increased capillary flow in intrahepatic tumors due to alpha-adrenergic effects of catecholamines.
    Cancer, 1988, Apr-15, Volume: 61, Issue:8

    Topics: Animals; Carcinoma 256, Walker; Epinephrine; Female; Isoproterenol; Liver Circulation; Liver Neoplas

1988
Redistribution of blood flow in experimental hepatic tumours with noradrenaline and propranolol.
    British journal of cancer, 1987, Volume: 56, Issue:5

    Topics: Animals; Drug Combinations; Drug Synergism; Liver Circulation; Liver Neoplasms, Experimental; Micros

1987