Page last updated: 2024-11-03

propranolol and Esophageal Varices

propranolol has been researched along with Esophageal Varices in 324 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to compare the recurrence of esophageal varices (EVs) after endoscopic band ligation (EBL) associated with propranolol (PP) versus EBL alone."9.20Propranolol associated with endoscopic band ligation reduces recurrence of esophageal varices for primary prophylaxis of variceal bleeding: a randomized-controlled trial. ( Bonilha, DQ; Correia, LM; de Paulo, GA; Della Libera, E; Ferrari, AP; Lenz, L; Rodrigues, RA, 2015)
"To compare transjugular intrahepatic portosystemic shunt (TIPS) placement with or without variceal embolization with endoscopic band ligation (EBL) plus propranolol in preventing recurrent esophageal variceal bleeding in patients with advanced cirrhosis and portal vein thrombosis."9.20Advanced Cirrhosis Combined with Portal Vein Thrombosis: A Randomized Trial of TIPS versus Endoscopic Band Ligation Plus Propranolol for the Prevention of Recurrent Esophageal Variceal Bleeding. ( Li, X; Luo, X; Tsauo, J; Wang, Z; Zhang, H; Zhou, B, 2015)
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."9.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
"In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months."9.11Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005)
" Forty consecutive patients with bleeding oesophageal varices underwent either injection sclerotherapy only or injection sclerotherapy with an adjuvant fixed daily dose of propranolol (40 mg tds) in a single-blind randomized controlled trial."9.11Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy. ( Abdel Baki, M; Dowidar, N; Hafez, A, 2005)
" Thus, a randomized double-blind trial was conducted to evaluate propranolol in the prevention of the development of large oesophageal varices in patients with cirrhosis without varices or with small varices."9.09Lack of effect of propranolol in the prevention of large oesophageal varices in patients with cirrhosis: a randomized trial. French-Speaking Club for the Study of Portal Hypertension. ( Abergel, A; Beauchant, M; Bichard, P; Blanc, P; Calés, P; Canva-Delcambre, V; Champigneulle, B; Guyader, D; Hadengue, A; Lebrec, D; Naveau, S; Oberti, F; Pascal, JP; Payen, JL; Poynard, T; Raymond, JM; Valla, D; Vetter, D, 1999)
"To assess the efficacy of Ligustrazine in combination with propranolol in the prevention of recurrent esophageal varices bleeding following liver cirrhosis, and its act mechanism."9.09[A randomized controlled study of ligustrazine in combination with propranolol for prevention of recurrent esophageal varices bleeding]. ( Chen, D; Li, X; Zou, J, 2000)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."9.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."9.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"To compare the efficacy of oral propranolol and sclerotherapy in the prevention of first hemorrhage from esophageal varices, 65 cirrhotic patients with moderate to large esophageal varices and no history of bleeding were included in the prospective controlled trial."9.07[Propranolol for prophylaxis of first hemorrhage in cirrhotic patients with esophageal varices--a controlled study comparing with sclerotherapy]. ( Kanazawa, H; Kobayashi, M; Kuroda, H; Matsusaka, S; Nakatsuka, K; Nomura, T; Saitoh, H; Tada, N; Watari, A; Yoshizawa, M, 1993)
"The objective of this randomized multicenter trial was to assess the prophylactic effect on the incidence and severity of the first variceal hemorrhage of endoscopic sclerotherapy, propranolol and the combination of the two compared with none of these treatments in patients with cirrhosis and esophageal varices."9.07Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients: a randomized multicenter trial. The PROVA Study Group. ( , 1991)
"Forty-one patients admitted with first episode of bleeding from esophageal varices were enrolled in a trial of the efficacy of oral propranolol to prevent rebleeding during the course of endoscopic sclerotherapy until obliteration."9.06Evaluation of propranolol for prevention of recurrent bleeding from esophageal varices between sclerotherapy sessions. ( Leth, R; Lind, T; Lönroth, H; Lundell, L; Olbe, L; Sjövall, M, 1990)
"In 29 patients admitted with their first bleeding episode from oesophageal varices the varices were obliterated within 6 months by treatment with serial endoscopic sclerotherapy and propranolol or with sclerotherapy only."9.06Propranolol may prevent recurrence of oesophageal varices after obliteration by endoscopic sclerotherapy. ( Jensen, LS; Krarup, N, 1990)
"Among the various treatments of ruptured oesophageal varices two seem to be effective: oral propranolol therapy and ligation of the oesophagus on clip."9.06[Prevention of recurrent hemorrhage caused by the rupture of esophageal varices in cirrhotic patients. A controlled study of propranolol and clip ligation of the esophagus]. ( Ampelas, M; Aubin, JP; Bauret, P; Bories, P; Daures, JP; Feneyrou, B; Guiry, P; Michel, H; Parelon, G; Prioton, JB, 1989)
"Thirty-one patients admitted with the first bleeding episode from oesophageal varices were randomized in a double-blind manner to receive oral propranolol, 160 mg daily, for 6 months (n = 15) or matching placebo (n = 16) for the same period."9.06Propranolol in prevention of rebleeding from oesophageal varices during the course of endoscopic sclerotherapy. ( Jensen, LS; Krarup, N, 1989)
"A prospective, randomised, multicentre, single-blind comparison of propranolol with placebo in the primary prevention of upper gastrointestinal haemorrhage was conducted in 230 cirrhotic patients with large oesophageal varices."9.06Propranolol in the primary prevention of upper gastrointestinal tract haemorrhage in patients with cirrhosis of the liver and oesophageal varices. ( Calès, P; Pascal, JP, 1989)
"To assess the beneficial and harmful effects of carvedilol compared with traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices."8.98Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices. ( Bendtsen, F; Gluud, LL; Hobolth, L; Jeyaraj, R; Morgan, MY; Zacharias, AP, 2018)
"There is no dose-dependent effect of 80-120 mg/day of propranolol on the hemodynamic response in cirrhotic patients with gastroesophageal varices."7.91Dose-dependent effect of propranolol on the hemodynamic response in cirrhotic patients with gastroesophageal varices. ( Chen, M; He, Q; Wang, Y; Xiao, J; Xu, H; Yin, X; Zhang, F; Zhang, M; Zhang, W; Zhuge, Y; Zou, X, 2019)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."7.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
"In the present study, we attempted to complete the hemodynamic assessment of propranolol response in cirrhotics with esophageal varices at high risk of bleeding, in one sitting, so as to identify nonresponders at the earliest."7.70Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: a hemodynamic evaluation. ( Biswas, J; Biswas, PK; De, BK; Hazra, B; Maity, AK; Santra, A; Sen, S; Sengupta, D, 2000)
"We describe a case of massive propranolol overdose in a healthy 19-year-old woman associated with isolated mesenteric ischemia following shock."7.68Nonocclusive mesenteric ischemia associated with propranolol overdose: implications regarding splanchnic circulation. ( Abramson, S; Levy, J; Pettei, MJ, 1990)
"The effect of a long-term propranolol administration on portal hemodynamics, liver function tests and endoscopic findings of esophageal varices were evaluated in 27 patients with established esophageal varices."7.68[A medical treatment of esophageal varices by propranolol]. ( Kimura, K; Ueno, N; Yamanaka, T, 1990)
"The effect of long-term propranolol administration on esophageal varices, portocollateral shunting, portal pressure, hepatosplanchnic hemodynamics, and liver function was studied in a pig model with experimentally induced prehepatic portal hypertension and esophageal varices."7.67Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices. ( Jensen, LS; Juhl, CO; Krarup, N; Larsen, JA; Nielsen, TH, 1989)
"A 52-year-old woman with primary biliary cirrhosis who had never had hepatic coma developed it while taking propranolol."7.67Does propranolol precipitate hepatic encephalopathy? ( Wiesner, RH, 1986)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."6.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Volume of para-esophageal varices (PEV) correlates with esophageal varices recurrence."6.80Endoscopic ultrasonography assessment of para-esophageal varices predicts efficacy of propranolol in preventing recurrence of esophageal varices. ( Chang, CJ; Chen, PH; Hou, MC; Lee, FY; Liao, WC; Lin, HC; Su, CW, 2015)
"No significant changes in the size of esophageal varices were observed after propranolol or placebo administration."6.67Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension. ( Bordas, JM; Bosch, J; Feu, F; Garcia-Pagán, JC; Rodés, J, 1991)
"The cause of recurrent bleeding was esophageal varices in nine patients and esophageal ulcers in five patients."6.37[Sclerotherapy of esophageal varices using ethanol in combination with propranolol: clinical study of 30 patients]. ( Aubert, A; Chaput, JC; Lemman, M; Naveau, S; Poynard, T, 1988)
"Propranolol is a non-selective beta-blocker used as secondary prophylaxis for UVB, but no previous studies have addressed carvedilol effects in rebleeding prevention."5.72Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis. ( Cançado, GGL; Cardoso, JB; Couto, CA; de Abreu, ES; Faria, LC; Ferrari, TCA; Lima, AMC; Nardelli, MJ; Osório, FMF, 2022)
" First-line therapies include carvedilol or propranolol to prevent variceal bleeding, lactulose for hepatic encephalopathy, combination aldosterone antagonists and loop diuretics for ascites, and terlipressin for hepatorenal syndrome."5.41Diagnosis and Management of Cirrhosis and Its Complications: A Review. ( Parikh, ND; Tapper, EB, 2023)
"The blood flow in esophageal varices was measured by endoscopic laser Doppler velocimetry (LDV) in 27 patients histologically or clinically diagnosed as having liver cirrhosis."5.28Effect of endoscopic sclerotherapy and propranolol on the blood flow of esophageal varices. ( Kodama, T; Murakami, M; Okano, H; Takino, T; Tsuji, H, 1990)
"100) rebled from esophageal varices within a mean time of 8."5.27[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice]. ( Attali, P; Buffet, C; Etienne, JP; Ink, O; Pelletier, G; Servent, L, 1985)
"The aim of this study was to compare the recurrence of esophageal varices (EVs) after endoscopic band ligation (EBL) associated with propranolol (PP) versus EBL alone."5.20Propranolol associated with endoscopic band ligation reduces recurrence of esophageal varices for primary prophylaxis of variceal bleeding: a randomized-controlled trial. ( Bonilha, DQ; Correia, LM; de Paulo, GA; Della Libera, E; Ferrari, AP; Lenz, L; Rodrigues, RA, 2015)
"To compare transjugular intrahepatic portosystemic shunt (TIPS) placement with or without variceal embolization with endoscopic band ligation (EBL) plus propranolol in preventing recurrent esophageal variceal bleeding in patients with advanced cirrhosis and portal vein thrombosis."5.20Advanced Cirrhosis Combined with Portal Vein Thrombosis: A Randomized Trial of TIPS versus Endoscopic Band Ligation Plus Propranolol for the Prevention of Recurrent Esophageal Variceal Bleeding. ( Li, X; Luo, X; Tsauo, J; Wang, Z; Zhang, H; Zhou, B, 2015)
" A total of 94 cirrhotic patients having large oesophageal varices without history of variceal bleeding were randomized to three treatment groups and given 2 months' treatment with propranolol plus placebo, propranolol plus antibiotics (norfloxacin 400 mg BD) or propranolol plus probiotic (VSL#3, 900 billion/day) randomly assigned in 1:1:1 ratio."5.17Effects of the adjunctive probiotic VSL#3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial. ( Garg, V; Gupta, N; Kumar, A; Sarin, SK; Sharma, BC; Sharma, P, 2013)
"To compare the effects of propranolol (PR) to that of PR plus isosorbide-5-mononitrate (ISMN) on variceal pressure in patients with schistosomiasis."5.17Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. ( Chen, C; Hao, JH; Kong, DR; Li, P; Ma, C; Wang, JG; Wang, M; Xu, JM; Zhang, L, 2013)
"Patients with oesophageal varices undergoing measurement of HVPG before and under propranolol treatment (80-160 mg/day) were included."5.17Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol. ( Ferlitsch, A; Heinisch, BB; Kramer, L; Payer, BA; Peck-Radosavljevic, M; Pinter, M; Reiberger, T; Schwabl, P; Trauner, M; Ulbrich, G, 2013)
"We chose 168 patients with cirrhosis and esophageal varices in our hospital and allocated them to EVL and propranolol groups."5.16[Comparison of endoscopic band ligation and propranolol for the primary prophylaxis of variceal bleeding in cirrhosis]. ( Feng, C; Huang, F; Liu, X; Nie, W; Ren, S, 2012)
"Prophylaxis EVL is as effective and as safe as treatment with propranolol in decreasing the incidence of first variceal bleeding and death in cirrhotic patients with high-risk esophageal varices."5.12Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis. ( Chen, CB; Lai, YL; Lay, CS; Lee, FY; Peng, CY; Tsai, YT; Yu, CJ, 2006)
"Twenty-five Japanese cirrhotic patients with endoscopically proven, likely to bleed esophageal varices were randomly assigned for propranolol administration (12 patients; group A) and EIS (13 patients; group B) to prevent first esophageal variceal bleeding."5.11Propranolol alone may not be acceptable to prevent first esophageal variceal bleeding in Japanese cirrhotic patients: randomized controlled trial. ( Akahoshi, T; Hashizume, M; Okita, K; Shimabukuro, R; Sugimachi, K; Tomikawa, M; Tsutsumi, N, 2004)
"In a multicenter, prospective trial, 62 patients with cirrhosis with high-risk esophageal varices were randomized to propranolol (titrated to reducing resting pulse by > or =25%) or banding (performed monthly until varices were eradicated) and were followed up on the same schedule for a mean duration of 15 months."5.11Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. ( Gornbein, J; Han, SH; Jensen, DM; Jutabha, R; Martin, P; Savides, T, 2005)
" This prospective randomized controlled trial compared EVL with drug therapy (propranolol + ISMN) in the prevention of rebleeds from esophageal varices in cirrhotic and noncirrhotic portal hypertension (NCPH) patients."5.11Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: comparison of cirrhotic and noncirrhotic patients. ( Gupta, R; Sarin, SK; Shahi, H; Wadhawan, M, 2005)
"Sixty patients with cirrhosis and oesophageal varices with no history but at high risk of bleeding were randomized to ligation treatment (30 patients) or propranolol (30 patients)."5.11Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial. ( Elefsiniotis, I; Galanis, P; Goulas, S; Liatsos, C; Mavrogiannis, C; Papanikolaou, IS; Psilopoulos, D; Sparos, L, 2005)
" Forty consecutive patients with bleeding oesophageal varices underwent either injection sclerotherapy only or injection sclerotherapy with an adjuvant fixed daily dose of propranolol (40 mg tds) in a single-blind randomized controlled trial."5.11Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy. ( Abdel Baki, M; Dowidar, N; Hafez, A, 2005)
" The aim of our study was to find out if propranolol can prevent the bleeding from esophageal varices and if it acts by reducing the portal inflow due to splanchnic vasodilatation."5.10Long term effects of propranolol on portal pressure in cirrhotic patients. ( Orban-Schiopu, AM; Popescu, CR, 2003)
"To compare the effectiveness of lanreotide SR, a new depot formulation injected once-weekly, and propranolol in reducing circadian portal blood flow (PVF) and meal-stimulated hepatic venous pressure gradient (HVPG) in patients with liver cirrhosis."5.10Effect of propranolol and depot lanreotide SR on postprandial and circadian portal haemodynamics in cirrhosis. ( Koch, L; Layer, G; Sauerbruch, T; Schiedermaier, P; Stoffel-Wagner, B, 2003)
"We compared propranolol therapy and endoscopic ligation for the primary prevention of bleeding from esophageal varices."5.09Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. ( Kumar, M; Lamba, GS; Misra, A; Murthy, NS; Sarin, SK, 1999)
"Thirty cirrhotic patients with PHT, grade III to IV oesophageal varices, hepatic venous pressure gradient > or = 12 mmHg and no prior history of upper gastrointestinal bleeding were randomized to receive propranolol (to reduce their pulse rate by 25% from baseline, n = 15) and EVL (weekly to fortnightly until variceal eradication, n = 15)."5.09Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial. ( Biswas, PK; Das, T; De, BK; Ghoshal, UC; Santra, A, 1999)
" Thus, a randomized double-blind trial was conducted to evaluate propranolol in the prevention of the development of large oesophageal varices in patients with cirrhosis without varices or with small varices."5.09Lack of effect of propranolol in the prevention of large oesophageal varices in patients with cirrhosis: a randomized trial. French-Speaking Club for the Study of Portal Hypertension. ( Abergel, A; Beauchant, M; Bichard, P; Blanc, P; Calés, P; Canva-Delcambre, V; Champigneulle, B; Guyader, D; Hadengue, A; Lebrec, D; Naveau, S; Oberti, F; Pascal, JP; Payen, JL; Poynard, T; Raymond, JM; Valla, D; Vetter, D, 1999)
"To assess the efficacy of Ligustrazine in combination with propranolol in the prevention of recurrent esophageal varices bleeding following liver cirrhosis, and its act mechanism."5.09[A randomized controlled study of ligustrazine in combination with propranolol for prevention of recurrent esophageal varices bleeding]. ( Chen, D; Li, X; Zou, J, 2000)
"Band ligation of esophageal varices may accentuate gastropathy, which in this study was partly relieved by propranolol."5.09The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial. ( Chen, TA; Cheng, JS; Chiang, HT; Hsu, PI; Lai, KH; Lin, CK; Lo, GH; Wang, EM, 2001)
"The absence of any effects on the parameters of portal haemodynamics would appear to deny clonidine any significant role in preventing first bleeding resulting from the rupture of oesophageal varices."5.08Effects of propranolol compared with clonidine on portal haemodynamics: a double-blind cross-over study using duplex-Doppler ultrasonography. ( Cioni, G; Cristani, A; D'Alimonte, P; Romagnoli, R; Tincani, E; Turrini, F; Ventura, E, 1995)
"The effect of spironolactone on esophageal variceal pressure (VP) in patients without ascites was investigated."5.08The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites. ( Fevery, J; Lijnen, P; Nevens, F; VanBilloen, H, 1996)
"To compare endoscopic sclerotherapy, propranolol and distal splenorenal shunt in the prevention of rebleeding esophageal varices and mortality in alcoholic cirrhotics."5.08Prevention of recurrent esophageal bleeding and survival in patients with alcoholic cirrhosis: a randomized study. ( Castro, F; Marquez, E; Medina, R; Molina, A; Oharriz, J; Rubio, CE; Torres, EA; Urbistondo, M, 1996)
" In the present, double-blind, 24-month, prospective study of patients with endoscopically-proven varices and ultrasonographically-confirmed hepatic fibrosis, the effects of propranolol 160 mg LA and placebo on the incidence of rebleeding and mortality were compared in 82 patients with portal hypertension secondary to schistosomiasis."5.07Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis. ( el Amin, AA; el Tourabi, H; Harron, DW; Homeida, M; Shaheen, M; Woda, SA, 1994)
"Propranolol has been shown to be effective in both primary and secondary treatment of variceal haemorrhage; most primary prevention trials have only included patients with large oesophageal varices."5.07Effect of propranolol on prevention of first variceal bleed and survival in patients with chronic liver disease. ( Bouchier, IA; Davies, JM; Elliot, R; Hayes, PC; Hislop, WS; Mills, PR; Plevris, JN, 1994)
"To compare the efficacy of oral propranolol and sclerotherapy in the prevention of first hemorrhage from esophageal varices, 65 cirrhotic patients with moderate to large esophageal varices and no history of bleeding were included in the prospective controlled trial."5.07[Propranolol for prophylaxis of first hemorrhage in cirrhotic patients with esophageal varices--a controlled study comparing with sclerotherapy]. ( Kanazawa, H; Kobayashi, M; Kuroda, H; Matsusaka, S; Nakatsuka, K; Nomura, T; Saitoh, H; Tada, N; Watari, A; Yoshizawa, M, 1993)
"The objective of this randomized multicenter trial was to assess the prophylactic effect on the incidence and severity of the first variceal hemorrhage of endoscopic sclerotherapy, propranolol and the combination of the two compared with none of these treatments in patients with cirrhosis and esophageal varices."5.07Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients: a randomized multicenter trial. The PROVA Study Group. ( , 1991)
"In a double-blind randomized trial, the hemodynamic events following the administration of propranolol (n = 51) or a placebo (n = 51) were prospectively studied in cirrhotic patients with esophageal varices."5.06Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. ( Alberts, J; Bermann, M; Bosch, J; Conn, HO; Fischer, R; Garcia-Tsao, G; Grace, ND; Groszmann, RJ; Navasa, M; Rodes, J, 1990)
"Propranolol and endoscopic sclerosis of esophageal varices are the two approaches currently used in prophylaxis of the first gastrointestinal hemorrhage in the cirrhotic patient."5.06Preventive therapy of first gastrointestinal bleeding in patients with cirrhosis: results of a controlled trial comparing propranolol, endoscopic sclerotherapy and placebo. ( Andreani, T; Balkau, BJ; Beaugrand, M; Grange, JD; Peigney, N; Poupon, R; Poupon, RE; Trinchet, JC, 1990)
"Forty-one patients admitted with first episode of bleeding from esophageal varices were enrolled in a trial of the efficacy of oral propranolol to prevent rebleeding during the course of endoscopic sclerotherapy until obliteration."5.06Evaluation of propranolol for prevention of recurrent bleeding from esophageal varices between sclerotherapy sessions. ( Leth, R; Lind, T; Lönroth, H; Lundell, L; Olbe, L; Sjövall, M, 1990)
"In 29 patients admitted with their first bleeding episode from oesophageal varices the varices were obliterated within 6 months by treatment with serial endoscopic sclerotherapy and propranolol or with sclerotherapy only."5.06Propranolol may prevent recurrence of oesophageal varices after obliteration by endoscopic sclerotherapy. ( Jensen, LS; Krarup, N, 1990)
"Among the various treatments of ruptured oesophageal varices two seem to be effective: oral propranolol therapy and ligation of the oesophagus on clip."5.06[Prevention of recurrent hemorrhage caused by the rupture of esophageal varices in cirrhotic patients. A controlled study of propranolol and clip ligation of the esophagus]. ( Ampelas, M; Aubin, JP; Bauret, P; Bories, P; Daures, JP; Feneyrou, B; Guiry, P; Michel, H; Parelon, G; Prioton, JB, 1989)
"Thirty-one patients admitted with the first bleeding episode from oesophageal varices were randomized in a double-blind manner to receive oral propranolol, 160 mg daily, for 6 months (n = 15) or matching placebo (n = 16) for the same period."5.06Propranolol in prevention of rebleeding from oesophageal varices during the course of endoscopic sclerotherapy. ( Jensen, LS; Krarup, N, 1989)
"A prospective, randomised, multicentre, single-blind comparison of propranolol with placebo in the primary prevention of upper gastrointestinal haemorrhage was conducted in 230 cirrhotic patients with large oesophageal varices."5.06Propranolol in the primary prevention of upper gastrointestinal tract haemorrhage in patients with cirrhosis of the liver and oesophageal varices. ( Calès, P; Pascal, JP, 1989)
"To assess the beneficial and harmful effects of carvedilol compared with traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices."4.98Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices. ( Bendtsen, F; Gluud, LL; Hobolth, L; Jeyaraj, R; Morgan, MY; Zacharias, AP, 2018)
"There is no dose-dependent effect of 80-120 mg/day of propranolol on the hemodynamic response in cirrhotic patients with gastroesophageal varices."3.91Dose-dependent effect of propranolol on the hemodynamic response in cirrhotic patients with gastroesophageal varices. ( Chen, M; He, Q; Wang, Y; Xiao, J; Xu, H; Yin, X; Zhang, F; Zhang, M; Zhang, W; Zhuge, Y; Zou, X, 2019)
"The clinical data of patients with gastroesophageal varices undergoing hepatic venous pressure gradient (HVPG) measurement before and 7 days after oral propranolol administration in our department were collected."3.83Influence of CYP2D6 and β2-adrenergic receptor gene polymorphisms on the hemodynamic response to propranolol in Chinese Han patients with cirrhosis. ( Duan, X; He, Q; Li, Z; Miao, C; Wang, Y; Zhang, F; Zhang, M; Zhong, W; Zhuge, Y; Zou, X, 2016)
"EVL plus propranolol is more effective than propranolol alone in the prevention of the first variceal bleeding in patients with liver cirrhosis."3.80The comparison of esophageal variceal ligation plus propranolol versus propranolol alone for the primary prophylaxis of esophageal variceal bleeding. ( Choi, MS; Gwak, GY; Je, D; Koh, KC; Lee, JH; Paik, SW; Paik, YH; Yoo, BC, 2014)
"The aim of this study was to describe the results of endoscopic secondary prophylaxis, alone or in combination with propranolol, used to prevent upper gastrointestinal bleeding (UGIB) in children and adolescents with esophageal varices."3.79Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices. ( Bittencourt, PF; Carvalho, SD; dos Santos, JM; Fagundes, ED; Ferreira, AP; Ferreira, AR; Ferreira, LS; Figueiredo Filho, PP; Magalhães, MC; Penna, FJ, 2013)
"Propranolol treatment has been used to prevent variceal bleeding; however, controlled trials of its effectiveness have produced conflicting results."3.76Drug therapy for portal hypertension. ( Rector, WG, 1986)
" This study was conducted to investigate any protective effect of early propranolol administration in the development and degree of esophageal varices in cirrhotic rats with portal hypertension."3.75Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats. ( Alatsakis, M; Ballas, KD; Marakis, GN; Pavlidis, TE; Psarras, K; Rafailidis, S; Sakantamis, AK; Tzioufa-Asimakopoulou, V, 2009)
"propranolol, has been shown to be effective in compensated patients with alcoholic cirrhosis."3.75[Pharmacological therapy of portal hypertension]. ( Miotti, T; Reichen, J, 1985)
" In 30 patients with liver cirrhosis at high risk for variceal bleeding, duplex Doppler sonographic parameters (maximal portal flow velocity, portal blood flow, and congestion index) were measured before and 4 h after the administration of 40 mg of propranolol."3.70Prevention of a first episode of variceal bleeding: role of duplex Doppler sonographic measurement of the acute response to beta-blockers. ( Baraldi, E; Boldrini, E; Cioni, G; Cristani, A; D'Alimonte, P; Pedrazzini, PG; Tincani, E; Turrini, F; Ventura, E; Ventura, P, 1999)
"In the present study, we attempted to complete the hemodynamic assessment of propranolol response in cirrhotics with esophageal varices at high risk of bleeding, in one sitting, so as to identify nonresponders at the earliest."3.70Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: a hemodynamic evaluation. ( Biswas, J; Biswas, PK; De, BK; Hazra, B; Maity, AK; Santra, A; Sen, S; Sengupta, D, 2000)
"Propranolol can reduce portal hypertension, therefore is recommended in prevention of variceal bleeding in patients with liver cirrhosis."3.69[Per-rectal scintigraphy of the portal system with pertechnetate TC-99M: effect of propranolol on portosystemic collateral circulation in patients with cirrhosis. Part II]. ( Bołdys, H; Hartleb, M; Nowak, A; Nowak, S; Rudzki, K, 1994)
"Propranolol is the only cost-effective form of prophylactic therapy for preventing initial variceal bleeding in cirrhosis regardless of bleeding risk."3.69Primary prophylaxis of variceal bleeding in cirrhosis: a cost-effectiveness analysis. ( Imperiale, TF; McCullough, AJ; Mullen, KD; Tavill, AS; Teran, JC, 1997)
"We describe a case of massive propranolol overdose in a healthy 19-year-old woman associated with isolated mesenteric ischemia following shock."3.68Nonocclusive mesenteric ischemia associated with propranolol overdose: implications regarding splanchnic circulation. ( Abramson, S; Levy, J; Pettei, MJ, 1990)
"The effect of a long-term propranolol administration on portal hemodynamics, liver function tests and endoscopic findings of esophageal varices were evaluated in 27 patients with established esophageal varices."3.68[A medical treatment of esophageal varices by propranolol]. ( Kimura, K; Ueno, N; Yamanaka, T, 1990)
"The effect of long-term propranolol administration on esophageal varices, portocollateral shunting, portal pressure, hepatosplanchnic hemodynamics, and liver function was studied in a pig model with experimentally induced prehepatic portal hypertension and esophageal varices."3.67Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices. ( Jensen, LS; Juhl, CO; Krarup, N; Larsen, JA; Nielsen, TH, 1989)
"The effectiveness of oral propranolol and sclerotherapy in preventing recurrent bleeding after an endoscopically proven haemorrhage from oesophageal varices was compared in Pugh's grade B and C patients divided into two successive therapeutic groups."3.67[Prevention of hemorrhagic recurrence in cirrhotic patients. Is sclerotherapy better than propranolol?]. ( Attali, P; Buffet, C; Etienne, JP; Fritsch, J; Honein, K; Ink, O; Pelletier, G, 1988)
"A 52-year-old woman with primary biliary cirrhosis who had never had hepatic coma developed it while taking propranolol."3.67Does propranolol precipitate hepatic encephalopathy? ( Wiesner, RH, 1986)
"To elucidate the mechanism by which propranolol reportedly affects portal hemodynamics, we investigated the effect of propranolol on systemic and splanchnic hemodynamics in 15 patients with portal hypertension and esophageal varices by simultaneous catheterization of the portal vein and the right hepatic vein and measurement of portal venous flow using an ultrasound doppler system."3.67Effects of propranolol on portal hemodynamics in patients with chronic liver disease. ( Hatano, H; Koen, H; Nakayama, T; Nomura, F; Ohnishi, K; Saito, M; Sugita, S; Terabayashi, H; Tsukamoto, T; Wada, K, 1985)
" The aim of this study was to evaluate the effects of 5-MTHF in combination with propranolol on HVPG and nitric oxide bioavailability markers in patients with cirrhosis and portal hypertension."3.305-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial. ( Andreone, P; Berzigotti, A; Bosch, J; Di Donato, R; Gitto, S; Renzulli, M; Roncarati, G; Schepis, F; Simoni, P; Villa, E; Vukotic, R, 2023)
"220 patients with known esophageal varices on upper GI endoscopy and no previous history of GI bleed were randomized to group A (Carvedilol) and group B (Propranolol)."3.30Comparison of carvedilol and propranolol for primary prophylaxis of esophageal variceal bleed in cirrhotic patients. ( Aneeza Ilyas, -; Khalid Mahmud Khan, -; Maria, -; Muhammad Adnan Iqbal, -; Muhammad Farooq Hanif, -; Nooman Gilani, -; Raja Omer Fiaz, -, 2023)
"Carvedilol is a non-selective beta-blocker (NSBB) acting on hyperdynamic circulation/splanchnic vasodilation and on intrahepatic resistance."3.01Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension. ( La Mura, V; Reiberger, T; Turco, L; Vitale, G, 2023)
"Carvedilol is a rising nonselective beta-blocker used for reducing portal pressure with favorable outcome."2.87Efficacy of carvedilol versus propranolol versus variceal band ligation for primary prevention of variceal bleeding. ( Abd ElRahim, AY; Elsharkawy, A; Fathalah, W; Fouad, R; Khairy, M; Khatamish, H; Khorshid, O; Moussa, M; Seyam, M, 2018)
"Propranolol has been used as prophylaxis for variceal bleeding in patients with cirrhosis."2.82A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis. ( Baik, SK; Jang, JY; Jeong, SW; Kim, DJ; Kim, MY; Kim, SG; Kim, TY; Kim, YS; Lee, B; Seo, YS; Sohn, JH; Suk, KT; Um, SH, 2016)
"Volume of para-esophageal varices (PEV) correlates with esophageal varices recurrence."2.80Endoscopic ultrasonography assessment of para-esophageal varices predicts efficacy of propranolol in preventing recurrence of esophageal varices. ( Chang, CJ; Chen, PH; Hou, MC; Lee, FY; Liao, WC; Lin, HC; Su, CW, 2015)
"Cirrhotics with large gastroesophageal varices type 2 with eradicated esophageal varices or large isolated gastric varix type 1, who had never bled from gastric varix, were randomised to cyanoacrylate injection (Group I, n=30), beta-blockers (Group II, n=29) or no treatment (Group III, n=30)."2.76Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial. ( Kumar, A; Mishra, SR; Sarin, SK; Sharma, BC, 2011)
"Primary end points were recurrence of variceal bleeding or death."2.75Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension. ( Agrawal, A; Gupta, N; Jha, SK; Kumar, A; Mishra, SR; Sarin, SK; Sharma, BC, 2010)
"Bleeding from gastric varices is often severe and difficult to manage."2.75Endoscopic cyanoacrylate injection versus beta-blocker for secondary prophylaxis of gastric variceal bleed: a randomised controlled trial. ( Chander Sharma, B; Kumar, A; Mishra, SR; Sarin, SK, 2010)
"Propranolol is a widely used drug for prophylaxis of variceal bleeding in patients with cirrhosis, but not all patients show an adequate clinical response."2.72Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices. ( De-Madaria, E; Hernández, FT; Horga, JF; Irurzun, J; Palazón, JM; Pascual, S; Perez-Mateo, M; Such, J; Zapater, P, 2006)
" However, the long-term use of this combination drug therapy is safe and may be an alternative in clinical conditions associated with a greater risk of bleeding."2.71Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: a double-blind RCT. ( Albillos, A; Balanzó, J; Bañares, R; Bosch, J; Calleja, JL; García-Durán, F; García-Pagán, JC; Genescà, J; Jimenez, M; Morillas, R; Planas, R; Rodriguez, M; Vila, C; Villanueva, C, 2003)
"The obliteration of esophageal and/or gastric varices using Histoacryl is highly effective in controlling active bleeding."2.71Endoscopic histoacryl obliteration vs. propranolol in the prevention of esophagogastric variceal rebleeding: a randomized trial. ( Delhaye, M; Devière, J; Dumonceau, JM; Evrard, S; Golstein, P; Le Moine, O, 2003)
" In Gr I, incremental dosage of propranolol (sufficient to reduce heart rate to 55 beats/min or 25% reduction from baseline) was administered and continued after obliteration of varices."2.71Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding. ( Agarwal, SR; Sarin, SK; Sharma, BC; Tyagi, P; Wadhawan, M, 2005)
"Hepatic encephalopathy was observed more often in the TIPS group (40."2.70Endoscopic variceal ligation plus propranolol vs. transjugular intrahepatic portosystemic stent shunt: a long-term randomized trial. ( Hansmann, J; Richter, GM; Sauer, P; Stiehl, A; Stremmel, W, 2002)
" Dosing of propranolol in the evening may be important for its role in preventing variceal bleeding."2.70Daily variation of azygos and portal blood flow and the effect of propranolol administration once an evening in cirrhotics. ( Ishii, K; Sasao, K; Sugano, S; Tanikawa, K; Watanabe, M; Yamamoto, K, 2001)
"Carvedilol is a relatively safe, effective portal hypotensive agent, both acutely and over 7 days, but not superior to propranolol, at least in Indians."2.70Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics. ( Biswas, PK; Das, D; De, BK; Maity, AK; Majumdar, D; Mandal, SK; Sen, S, 2002)
"Propranolol was well tolerated with minimal side effects in our patients with portal hypertension."2.69Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study. ( Grand, RJ; Langhans, N; Shashidhar, H, 1999)
"The incidence of clinically significant hepatic encephalopathy after 1 year was higher in the shunt group (36% vs 18%, p = 0."2.68Randomised trial of transjugular-intrahepatic-portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding. ( Blum, HE; Deibert, P; Geiger, R; Haag, K; Hauenstein, KH; Keller, W; Ochs, A; Olschewski, M; Rössle, M; Siegerstetter, V; Stiepak, C, 1997)
"Hepatic encephalopathy was observed in 29% of the patients in the TIPS group and in 13% of those in the ES group (P = 0."2.68Transjugular intrahepatic portosystemic stent shunt versus sclerotherapy plus propranolol for variceal rebleeding. ( Benz, C; Richter, GM; Sauer, P; Stiehl, A; Stremmel, W; Theilmann, L, 1997)
"Eighteen cirrhotic patients with esophageal varices at risk for bleeding took part in a double-blind study."2.67Duplex Doppler ultrasonographic comparison of the effects of propranolol and isosorbide-5-mononitrate on portal hemodynamics. ( Abbati, G; Cioni, G; Cristani, A; D'Alimonte, P; Romagnoli, R; Tincani, E; Ventura, E; Ventura, P; Vignoli, A, 1993)
" The present study was aimed at comparing the efficacy of endoscopic sclerotherapy and long-term administration of propranolol in the prevention of rebleeding and long-term survival in patients who had bled from varices."2.67Propranolol versus sclerotherapy in preventing variceal rebleeding: a randomized controlled trial. ( Bordas, JM; Bosch, J; Cirera, I; Feu, F; Garcia Pagán, JC; Rodés, J; Terés, J, 1993)
"Bleeding recurrence was less frequent in the treated patients (Kaplan Meier analysis p < 0."2.67[Prevention of digestive hemorrhage recurrence in hepatic cirrhosis with propranolol. A 4 years' follow-up study]. ( Armas, R; Jirón, MI; Soto, JR; Wolff, C, 1993)
"Propranolol dose was adjusted to reduce the resting heart rate by 25% of the basal value (mean +/- SD, 194."2.67Endoscopic sclerotherapy versus propranolol in prevention of recurrent variceal bleeding in patients with child's B and C cirrhosis: a preliminary report. ( Bhargava, DK; Dwivedi, M; Ramachandran, K, 1992)
"When considering only rebleedings from esophageal varices, 4 patients rebled in group 2 vs."2.67Propranolol reduces the rebleeding rate during endoscopic sclerotherapy before variceal obliteration. ( Barjonet, G; Barjonnet, G; Cales, P; Combis, JM; Desmorat, H; Lamouliatte, H; Pradere, B; Quinton, A; Roux, D; Vinel, JP, 1992)
"Propranolol was given twice daily with a mean final dose of 54 +/- 16 mg/day, this resulted in a mean reduction in resting heart rate of 26 +/- 7%."2.67Prevention of recurrent variceal bleeding in alcoholic cirrhotic patients: prospective controlled trial of propranolol and sclerotherapy. ( Boyer, J; Burtin, P; Calès, P; Charneau, J; D'Aubigny, N; Joubaud, F; Person, B; Pujol, P; Rossi, V; Valentin, S, 1991)
" Daily dosage was determined by the administration of progressively increasing doses of propranolol with the hepatic vein catheter in place to achieve a 25% decrease in hepatic venous pressure gradient, a decrease in hepatic venous pressure gradient to less than 12 mm Hg or a decrease in resting heart rate to less than 55 beats/min."2.67Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. The Boston-New Haven-Barcelona Portal Hypertension Study Group. ( Bosch, J; Conn, HO; Fisher, RL; Garcia-Tsao, G; Grace, ND; Groszmann, RJ; Matloff, DS; Navasa, M; Rodés, J; Wright, SC, 1991)
"No significant changes in the size of esophageal varices were observed after propranolol or placebo administration."2.67Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension. ( Bordas, JM; Bosch, J; Feu, F; Garcia-Pagán, JC; Rodés, J, 1991)
" Patients were chosen randomly to receive oral propranolol (in a dosage to reduce resting pulse rate by 25%) or to undergo long-term injection sclerotherapy."2.67A controlled trial of oral propranolol compared with injection sclerotherapy for the long-term management of variceal bleeding. ( Gimson, AE; Hayes, PC; Hayllar, K; Polson, RJ; Westaby, D; Williams, R, 1990)
"Study endpoints were severe recurrence of variceal hemorrhage or death."2.67Propranolol in the prevention of recurrent variceal hemorrhage in cirrhotic patients. A controlled trial. ( Birnie, GG; Carter, DC; Garden, OJ; Mills, PR; Murray, GD, 1990)
"Atenolol was given at a fixed dose of 100 mg per day."2.66Beta-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis: a multicenter randomized controlled trial. ( Colombo, M; de Franchis, R; Dioguardi, N; Sangiovanni, A; Tommasini, M, 1989)
"Propranolol is a useful medicament for the reduction of esophagic varices size and prevention of digestive bleeding in cirrhotic patients."2.66[Propranolol in the prevention of digestive bleeding in cirrhotic patients]. ( Castro, R; Glez Cansino, J; Sotto, A, 1989)
"This may in turn depend on the recurrence of bleeding."2.66Reduction in early recurrence of variceal bleeding by propranolol. ( Beglinger, C; Bögtlin, J; Gyr, KE; Kiowski, W; Loosli, J; Marbet, UA; Ritz, R; Schaub, N; Stalder, GA; Straumann, A, 1988)
"Propranolol dosage was titrated according to blood levels."2.66Systemic and hepatic hemodynamics after variceal hemorrhage: effects of propranolol and placebo. ( Huet, PM; Marleau, D; Pomier-Layrargues, G; Villeneuve, JP; Willems, B, 1987)
"Recent advances in the pharmacologic treatment of portal hypertension have mainly focused on modifying an increased intrahepatic resistance through nitric oxide and/or modulation of vasoactive substances."2.61Pharmacologic Management of Portal Hypertension. ( Bunchorntavakul, C; Reddy, KR, 2019)
"Frequently, relevant liver fibrosis is diagnosed by non-invasive methods (e."2.58[Management of compensated liver cirrhosis 2018 - Evidence based prophylactic measures]. ( Benten, D; Karkmann, K; Kluwe, J; Piecha, F; Rünzi, AC; Schulz, L; von Wulffen, M; Wege, H, 2018)
"According to their location, gastric varices (GV) are classified as gastroesophageal varices and isolated gastric varices."2.50Management of gastric varices. ( Barrufet, M; Cardenas, A; Escorsell, A; Garcia-Pagán, JC, 2014)
"Pregnancy is rare in women with decompensated chronic liver disease."2.47Successful pregnancy outcome in decompensated chronic liver disease with portal vein thrombosis: case report and review of literature. ( Hussain, R; Kamani, L; Kumar, M; Siddique, S, 2011)
"Bacterial infections have been hypothetized to be a trigger of variceal bleeding in cirrhotic patients and beta-blockers may have a protective effect by decreasing bacterial translocation, reducing portal pressure."2.45beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis. ( Burra, P; Burroughs, AK; Cholongitas, E; Leandro, G; Patch, D; Senzolo, M; Thalheimer, U, 2009)
"Carvedilol appears to be a potentially viable option for treating portal hypertension."2.42Evaluation of carvedilol for the treatment of portal hypertension. ( Hemstreet, BA, 2004)
"Terlipressin has longer effects and is more effective and safer than vasopressin alone or in combination with nitroglycerin."2.41The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage. ( Bosch, J, 2000)
"Hemorrhage from esophageal varices is a life-threatening event in patients with liver cirrhosis."2.39Beta-blockers for prophylaxis of bleeding from esophageal varices in cirrhotic portal hypertension. Review of the literature. ( Gross, M; Zoller, WG, 1996)
"The best results obtained in treatment of portal hypertension were: esophagogastric devascularization and splenectomy (EGDS), although risk of rebleeding persists; classical (proximal) splenorenal shunt (SRS) should be abandoned; distal splenorenal shunt may complicate with hepatic encephalopathy, although later and in a lower percentage than in SRS."2.38Portal hypertension in schistosomiasis: pathophysiology and treatment. ( Da Silva, LC, 1992)
"Bleeding from esophagogastric varices carries a high mortality rate."2.38Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence. ( Marshall, JB, 1991)
"Only about one third of patients with esophageal varices eventually bleed."2.38[Treatment of hemorrhage of esophageal varices]. ( Sauerbruch, T, 1990)
"The development of bleeding esophagogastric varices and the methods used to treat this complication are all unsatisfactory either in the short or long term."2.37Theoretical and practical considerations in the treatment of portal hypertension secondary to hepatic cirrhosis. ( Bizer, LS, 1984)
"The cause of recurrent bleeding was esophageal varices in nine patients and esophageal ulcers in five patients."2.37[Sclerotherapy of esophageal varices using ethanol in combination with propranolol: clinical study of 30 patients]. ( Aubert, A; Chaput, JC; Lemman, M; Naveau, S; Poynard, T, 1988)
"Bleeding from esophageal varices remains a difficult clinical problem, carrying a high likelihood both of rebleeding and of mortality."2.37Management of the patient with hemorrhaging esophageal varices. ( Cello, JP; Crass, RA; Grendell, JH; Trunkey, DD, 1986)
"Peptic ulcer disease, oesophageal varices and Mallory-Weiss tear are the major causes."2.36Management of upper gastrointestinal haemorrhage. ( Korman, MG, 1983)
"Propranolol is a non-selective beta-blocker used as secondary prophylaxis for UVB, but no previous studies have addressed carvedilol effects in rebleeding prevention."1.72Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis. ( Cançado, GGL; Cardoso, JB; Couto, CA; de Abreu, ES; Faria, LC; Ferrari, TCA; Lima, AMC; Nardelli, MJ; Osório, FMF, 2022)
"Her pregnancy was uneventful until 31 weeks gestation when she presented with dyspnoea."1.48Pregnancy in a patient with portal hypertension secondary to liver cirrhosis. ( Lelei-Mailu, FJ; Mariara, CM, 2018)
"Pregnancy with liver cirrhosis is a rare and dangerous event that exposes mother and fetus to potentially lethal risks."1.43Successful pregnancy with autoimmune cirrhosis. ( Braga, A; Braga, J, 2016)
"Propranolol was associated with reduction in bleeding episodes (P < 0."1.42Extrahepatic portal vein obstruction in Egyptian children. ( El-Karaksy, HM; El-Koofy, N; El-Shabrawi, M; Helmy, H; Mohsen, N; Nabil, N, 2015)
" We aimed to evaluate the dosing and tolerance of BBs achievable in a specialized, nurse-run BB titration clinic with non-trial participants."1.36A specialized, nurse-run titration clinic: a feasible option for optimizing beta-blockade in non-clinical trial patients. ( Abraldes, JG; Berzigotti, A; Bosch, J; Garcia-Pagan, JC; Saez, R; Tandon, P, 2010)
"All of them had high-risk esophageal varices at endoscopy."1.35Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension. ( Bittencourt, PL; Carrilho, FJ; da Rocha, EC; Dos Santos Bomfim, V; Farias, AQ; Kassab, F; Vezozzo, DC, 2009)
"The variceal recurrence rate was 65 and 38."1.32Long-term outcome after sclerotherapy with or without a beta-blocker for variceal bleeding in children. ( Elkabes, B; Saner, G; Sökücü, S; Süoglu, OD, 2003)
"Ectopic intestinal varices are rarely responsible for lower gastrointestinal (GI) haemorrhage."1.32Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage. ( Ahmed, I; Alam, A; Alvi, A; Butt, AK; Khan, AA; Niazi, A; Sarwar, S; Shafqat, F; Tarique, S, 2003)
"Management of patients with bleeding oesophageal varices comprises of mainly diagnostic endoscopy, sclerotherapy and band ligation."1.32Can somatostatin control acute bleeding from oesophageal varices in Schistosoma mansoni patients?[ISRCTN63456799]. ( Chatterjee, S; Van Marck, E, 2004)
"Larger gastric varices have been shown to be the only risk factor for rebleeding (adjusted odds ratio, 4."1.31Pharmacologic efficacy in gastric variceal rebleeding and survival: including multivariate analysis. ( Chen, GH; Wu, CY; Yeh, HZ, 2002)
"Data from a controlled clinical trial in liver cirrhosis are used to illustrate that multi-state models may be a useful tool in the analysis of data where survival is the ultimate outcome of interest but where intermediate, transient states are identified."1.31Multi-state models for bleeding episodes and mortality in liver cirrhosis. ( Andersen, PK; Esbjerg, S; Sorensen, TI, 2000)
" It was decided that patients whose portal pressure was reduced by 30% with the use of the drug would not undergo surgery and that treatment would consist of the chronic use of propranolol, associated with sclerosis of esophageal varices."1.30Systemic and hepatic hemodynamics in hepatosplenic Manson's schistosomiasis with and without propranolol. ( Alfieri, F; Baía, CE; Beer, A; Mies, S; Neto, OB; Pereira, LM; Raia, S; Sette, MJ, 1997)
"The true form of portal hypertension is considered to be congestive gastropathy from the points that PHG is observed in high frequencies in the high portal pressure group, the severe esophageal varices group and group without gastrorenal or splenorenal shunt, that the mucosal blood flow rate in the lesion increased and that venectasia is present in the submucosal layer."1.29[Study of gastric mucosal lesion in portal hypertension]. ( Maruyama, T, 1995)
"The results of esophageal varices treatment in two groups of patients are shown."1.28[Sclerosing treatment of esophageal varices]. ( Jorge, AD; Milutin, C; Oliver, J, 1991)
"The blood flow in esophageal varices was measured by endoscopic laser Doppler velocimetry (LDV) in 27 patients histologically or clinically diagnosed as having liver cirrhosis."1.28Effect of endoscopic sclerotherapy and propranolol on the blood flow of esophageal varices. ( Kodama, T; Murakami, M; Okano, H; Takino, T; Tsuji, H, 1990)
"Since the gastritis is related to vascular changes and congestion of the stomach wall secondary to increased portal pressure, and not inflammation, measures aimed at local healing or surgical removal of the bleeding area fail."1.27Persistent hemorrhagic gastritis in a patient with portal hypertension and esophagogastric varices: the role of portal decompressive surgery. ( Babb, RR; Mitchell, RL, 1988)
"Sclerotherapy of esophageal varices consists in obstruction of the varicosities."1.27[Prevention of recurrent hemorrhage due to portal hypertension]. ( Lebrec, D, 1986)
"100) rebled from esophageal varices within a mean time of 8."1.27[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice]. ( Attali, P; Buffet, C; Etienne, JP; Ink, O; Pelletier, G; Servent, L, 1985)
"Propranolol was administered to 5 patients, in doses of 60-80 mg daily."1.26Injection sclerotherapy of esophageal varices. ( Jorge, AD, 1982)

Research

Studies (324)

TimeframeStudies, this research(%)All Research%
pre-199083 (25.62)18.7374
1990's100 (30.86)18.2507
2000's66 (20.37)29.6817
2010's59 (18.21)24.3611
2020's16 (4.94)2.80

Authors

AuthorsStudies
de Abreu, ES1
Nardelli, MJ1
Lima, AMC1
Cardoso, JB1
Osório, FMF1
Ferrari, TCA1
Faria, LC1
Couto, CA1
Cançado, GGL1
Mao, G1
Li, C1
Wang, H1
Jv, YH1
Zhang, Y1
Liu, L1
Singh, V1
Kumar, P1
Verma, N1
Vijayvergiya, R1
Singh, A1
Bhalla, A1
Nabilou, P1
Danielsen, KV1
Kimer, N2
Hove, JD1
Bendtsen, F5
Møller, S2
Hofer, BS1
Simbrunner, B2
Bauer, DJM1
Paternostro, R2
Schwabl, P3
Scheiner, B2
Semmler, G1
Hartl, L2
Jachs, M2
Datterl, B1
Staettermayer, AF1
Trauner, M4
Mandorfer, M3
Reiberger, T6
Bauer, D1
Balcar, L1
Hofer, B1
Pfisterer, N1
Schwarz, M1
Stättermayer, AF1
Pinter, M3
Turco, L1
Vitale, G2
La Mura, V1
Tapper, EB1
Parikh, ND1
Vukotic, R2
Di Donato, R1
Roncarati, G1
Simoni, P1
Renzulli, M1
Gitto, S1
Schepis, F1
Villa, E1
Berzigotti, A2
Bosch, J17
Andreone, P2
Muhammad Farooq Hanif, -1
Raja Omer Fiaz, -1
Muhammad Adnan Iqbal, -1
Aneeza Ilyas, -1
Maria, -1
Khalid Mahmud Khan, -1
Nooman Gilani, -1
Wang, X1
Liu, G1
Wu, J1
Xiao, X1
Yan, Y1
Guo, Y1
Yang, J1
Li, X6
He, Y1
Yang, L1
Luo, X3
Bunchorntavakul, C1
Reddy, KR1
Yoo, JJ1
Kim, SG3
Kim, YS3
Lee, B2
Jeong, SW3
Jang, JY3
Lee, SH2
Kim, HS2
Jun, BG1
Kim, YD1
Cheon, GJ1
Raimondi, F1
Brodosi, L1
Petroni, ML1
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Gauthier, F1
Alagille, D1
Scheurlen, M1
Egberts, EH1
Dölle, W1
Bardet-Tassin, P1
Lévy, VG1
Servent, L1
Ohnishi, K1
Nakayama, T1
Saito, M1
Hatano, H1
Tsukamoto, T1
Terabayashi, H1
Sugita, S1
Wada, K1
Nomura, F1
Koen, H1
Schalm, SW1
Okumura, H1
Sekiyama, T1
Katsuta, Y1
Akaike, M1
Sekino, M1
Terada, H1
Satomura, K1
Aramaki, T1
Sesoko, M1
Honda, M1
Nakajima, K1
Hirosawa, K1
Onoda, B1
Yoshida, Y1
Onishi, S1
Meves, M1
Meiisel, P1
Rösch, J1
Dotter, CT1
Rose, RW1

Clinical Trials (19)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites[NCT02649335]Phase 3190 participants (Actual)Interventional2015-07-01Completed
VICIS - Vienna Cirrhosis Study[NCT03267615]10,000 participants (Anticipated)Observational [Patient Registry]2017-02-01Recruiting
Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis (PVT): A Multicenter Randomized Trial[NCT06122753]120 participants (Anticipated)Interventional2024-01-31Not yet recruiting
HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)[NCT03783065]40 participants (Anticipated)Interventional2019-01-02Recruiting
Transjugular Intrahepatic Portosystemic Shunt Versus Endoscopic Treatment Combined With Propranolol for Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis: A Randomized Controlled Trial[NCT01326949]52 participants (Actual)Interventional2011-05-31Completed
A Prospective Multicenter Cohort Study on the Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in Cirrhosis[NCT04932200]608 participants (Anticipated)Observational2021-06-15Not yet recruiting
Timing of Endoscopic Intervention in Patients With Cirrhosis With Acute Variceal Upper Gastrointestinal Hemorrhage (TEACH Trial): a Randomized Clinical Trial[NCT04786743]400 participants (Anticipated)Interventional2021-04-20Recruiting
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis: a Prospective Cohort Study[NCT04543643]Phase 3288 participants (Anticipated)Interventional2021-11-01Not yet recruiting
Prevention of Progression of Portal Hypertension in Compensated Cirrhosis Using Selective Hepatic Vasodilators. A Double-blind, Multicenter,Randomized Controlled Trial[NCT01282398]Phase 480 participants (Anticipated)Interventional2011-04-30Not yet recruiting
Banding Ligation Plus Propranolol Versus Banding Ligation to Prevent Rebleeding of Esophageal Varices[NCT02740166]Phase 4212 participants (Anticipated)Interventional2013-06-30Recruiting
Comparison of Endoscopic Variceal Ligation (EVL) and Propranolol in Secondary Prophylaxis of Variceal Bleeding in Patients With Non Cirrhotic Portal Hypertension (NCPH): A Prospective Randomized Controlled Trial[NCT01000779]Phase 3100 participants (Anticipated)Interventional2005-01-31Completed
Endoscopic Cyanoacrylate Injection Versus Beta-Blockers for Secondary Prophylaxis of Gastric Variceal Bleed[NCT00888784]64 participants (Actual)Interventional2006-08-31Completed
EUS-guided Combined Therapy of Coiling and 2-octyl-cyanoacrylate Injection With Beta Blocker Therapy Versus Beta Blocker Alone for the Primary Prophylaxis of GOV II and IGV I[NCT04075760]26 participants (Anticipated)Interventional2019-08-01Recruiting
A Randomized Controlled Trial Comparing Cyanoacrylate Injection Versus Beta-Blockers Versus No Treatment for Primary Prophylaxis of Gastric Variceal Bleed[NCT00905996]74 participants (Actual)Interventional2006-08-31Completed
Prospective Cohort Study to Evaluate Long-term Outcomes in Patients With Liver Cirrhosis of Boramae Hospital[NCT01943318]500 participants (Actual)Observational [Patient Registry]2013-01-31Completed
Is Capsule Endoscopy Accurate and Cost-effective Enough to Screen Cirrhotic Patients for Varices & Other Lesions?[NCT01079416]65 participants (Actual)Observational2006-06-30Completed
Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252]Phase 119 participants (Actual)Interventional2013-10-31Completed
CHESS-SAVE Score to Stratify Decompensation Risk in Compensated Advanced Chronic Liver Disease: an International Multicenter Study (CHESS2102)[NCT04975477]1,000 participants (Anticipated)Observational2021-07-16Not yet recruiting
Propanolol for Primary Prophylaxis for Variceal Bleed in Biliary Atresia - An Open Label Randomized Controlled Study[NCT04494763]92 participants (Anticipated)Interventional2020-08-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

52 reviews available for propranolol and Esophageal Varices

ArticleYear
Exploration on the Effect of Nonselective
    BioMed research international, 2022, Volume: 2022

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; He

2022
Carvedilol as the new non-selective beta-blocker of choice in patients with cirrhosis and portal hypertension.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:6

    Topics: Adrenergic beta-Antagonists; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal H

2023
Diagnosis and Management of Cirrhosis and Its Complications: A Review.
    JAMA, 2023, 05-09, Volume: 329, Issue:18

    Topics: Adult; Ascites; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hepatic Enc

2023
Pharmacologic Management of Portal Hypertension.
    Clinics in liver disease, 2019, Volume: 23, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anticoagulants; Antihypertensi

2019
Pharmacologic prevention of variceal bleeding and rebleeding.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Atorvastatin; Carbazoles; Carvedilol; Esophageal and Gastric Varices; G

2018
[Management of compensated liver cirrhosis 2018 - Evidence based prophylactic measures].
    Zeitschrift fur Gastroenterologie, 2018, Volume: 56, Issue:1

    Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Germany; Hepatic Encephalop

2018
Carvedilol versus traditional, non-selective beta-blockers for adults with cirrhosis and gastroesophageal varices.
    The Cochrane database of systematic reviews, 2018, Oct-29, Volume: 10

    Topics: Adrenergic beta-Antagonists; Adult; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hem

2018
Management of gastric varices.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2014, Volume: 12, Issue:6

    Topics: Anti-Bacterial Agents; Balloon Occlusion; Cardiovascular Agents; Cyanoacrylates; Esophageal and Gast

2014
Combined therapies versus monotherapies for the first variceal bleeding in patients with high-risk varices: a meta-analysis of randomized controlled trials.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Combined Modality Therapy; Databases, Bibliographic; Drug Therapy, Combination; Endpoint Determinati

2014
Beta-blockers in cirrhosis and refractory ascites: a retrospective cohort study and review of the literature.
    Scandinavian journal of gastroenterology, 2015, Volume: 50, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Ascites; Case-Control Studies; Esophageal and Gastric Varices; Fe

2015
Carvedilol for portal hypertension in cirrhosis: systematic review with meta-analysis.
    BMJ open, 2016, 05-04, Volume: 6, Issue:5

    Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Esophageal and Ga

2016
Beta-blockers in the prevention of gastrointestinal bleeding.
    Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 1990, Volume: 42 Suppl

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Esophageal and Gastr

1990
beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:8

    Topics: Adrenergic beta-Antagonists; Bacterial Infections; Bacterial Translocation; Databases, Bibliographic

2009
Successful pregnancy outcome in decompensated chronic liver disease with portal vein thrombosis: case report and review of literature.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:7

    Topics: Adult; Antiviral Agents; Ascites; Blood Transfusion; Esophageal and Gastric Varices; Female; Hepatit

2011
Prognostic markers in patients who have recovered from an acute variceal bleeding: role of HVPG measurement.
    Disease markers, 2011, Volume: 31, Issue:3

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Biomarkers; Esophageal and Gastric Varices; Ga

2011
Pharmacotherapy alone vs endoscopic variceal ligation combination for secondary prevention of oesophageal variceal bleeding: meta-analysis.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:5

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscop

2012
Bleeding from ruptured oesophageal varices: propranolol for primary prevention.
    Prescrire international, 2012, Volume: 21, Issue:125

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Diuretics; Endoscopy; Esophageal and Gastric

2012
Evaluation of carvedilol for the treatment of portal hypertension.
    Pharmacotherapy, 2004, Volume: 24, Issue:1

    Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Fibrosis; Humans; Hy

2004
Cirrhotic portal hypertension: current and future medical therapy for primary and secondary prevention of variceal bleeding.
    Minerva medica, 2006, Volume: 97, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Contraindications; Drug Therapy, Combination; Endoscopy; Esoph

2006
[The effect of propranolol on portal hypertension].
    Srpski arhiv za celokupno lekarstvo, 1992, Volume: 120 Suppl 4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

1992
Medical treatment of portal hypertension and oesophageal varices.
    British medical journal (Clinical research ed.), 1983, Sep-10, Volume: 287, Issue:6394

    Topics: Blood Flow Velocity; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hem

1983
Non-operative management of variceal bleeding.
    The British journal of surgery, 1984, Volume: 71, Issue:2

    Topics: Electrocoagulation; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemo

1984
Management of upper gastrointestinal haemorrhage.
    Annals of the Academy of Medicine, Singapore, 1983, Volume: 12, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Embolization, Therapeutic; Esophageal and Gastric Varices; E

1983
Theoretical and practical considerations in the treatment of portal hypertension secondary to hepatic cirrhosis.
    The American surgeon, 1984, Volume: 50, Issue:10

    Topics: Animals; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal;

1984
[Typical risks in the treatment of acute and chronic liver diseases].
    Der Internist, 1982, Volume: 23, Issue:3

    Topics: Androgens; Ascites; Cholestyramine Resin; Cimetidine; Disseminated Intravascular Coagulation; Diuret

1982
Oesophageal varices prior to bleeding. Diagnosis and physiological and therapeutic effects of propranolol in cirrhosis.
    Danish medical bulletin, 1993, Volume: 40, Issue:3

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Liver Cirrhosis;

1993
Drug treatment of esophageal variceal bleeding: alternative or supplement to endoscopic therapy?
    Endoscopy, 1995, Volume: 27, Issue:8

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscop

1995
Beta-blockers for prophylaxis of bleeding from esophageal varices in cirrhotic portal hypertension. Review of the literature.
    European journal of medical research, 1996, Jun-25, Volume: 1, Issue:9

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointest

1996
Portal-hypertensive gastropathy.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:9

    Topics: Esophageal and Gastric Varices; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; H

1998
The sixth Carlos E. Rubio Memorial Lecture. Prevention and treatment of variceal hemorrhage.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination

2000
Portal hypertension in schistosomiasis: pathophysiology and treatment.
    Memorias do Instituto Oswaldo Cruz, 1992, Volume: 87 Suppl 4

    Topics: Animals; Cricetinae; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage;

1992
Prevention of first variceal bleeding: new prospects.
    JPMA. The Journal of the Pakistan Medical Association, 1992, Volume: 42, Issue:2

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointesti

1992
Balloon tamponade and vasoactive drugs in the control of acute variceal haemorrhage.
    Bailliere's clinical gastroenterology, 1992, Volume: 6, Issue:3

    Topics: Antihypertensive Agents; Balloon Occlusion; Catheterization; Esophageal and Gastric Varices; Gastroi

1992
Portal hypertensive gastropathy.
    Bailliere's clinical gastroenterology, 1992, Volume: 6, Issue:3

    Topics: Animals; Diagnosis, Differential; Esophageal and Gastric Varices; Gastric Mucosa; Gastritis; Gastroi

1992
Beta-adrenergic antagonists for primary prevention of gastrointestinal hemorrhage in patients with cirrhosis and esophageal varices.
    Clinical pharmacy, 1992, Volume: 11, Issue:4

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Nadolol; Propr

1992
Propranolol in variceal hemorrhage.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:1

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1992
Bleeding esophagogastric varices. Ways to treat active episodes and prevent recurrence.
    Postgraduate medicine, 1991, May-01, Volume: 89, Issue:6

    Topics: Balloon Occlusion; Catheterization; Clinical Protocols; Education, Medical, Continuing; Endoscopy, G

1991
Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials. Franco-Italian Multicenter
    The New England journal of medicine, 1991, May-30, Volume: 324, Issue:22

    Topics: Adrenergic beta-Antagonists; Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemor

1991
[Chemotherapy of portal hypertension].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:4

    Topics: Antihypertensive Agents; Drug Evaluation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhag

1991
Meta-analysis of value of propranolol in prevention of variceal haemorrhage.
    Lancet (London, England), 1990, Jul-21, Volume: 336, Issue:8708

    Topics: Adrenergic beta-Antagonists; Chi-Square Distribution; Drug Evaluation; Esophageal and Gastric Varice

1990
[Primary prevention of digestive hemorrhages in cirrhotic patients].
    Annales de gastroenterologie et d'hepatologie, 1990, Volume: 26, Issue:5

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Li

1990
[Treatment of hemorrhage of esophageal varices].
    Leber, Magen, Darm, 1990, Volume: 20, Issue:1

    Topics: Balloon Occlusion; Catheterization; Combined Modality Therapy; Esophageal and Gastric Varices; Gastr

1990
Prevention of recurrent variceal hemorrhage: to block or not to block?
    The American journal of gastroenterology, 1990, Volume: 85, Issue:5

    Topics: Atenolol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Prop

1990
[Pharmacological therapy of portal hypertension].
    Schweizerische medizinische Wochenschrift, 1985, Oct-19, Volume: 115, Issue:42

    Topics: Acute Disease; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Esophageal an

1985
Advances in managing variceal bleeding in portal hypertension.
    Surgery annual, 1986, Volume: 18

    Topics: Catheterization; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemorrh

1986
Drug therapy for portal hypertension.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Animals; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemo

1986
Pharmacological therapy of portal hypertension.
    Digestive diseases (Basel, Switzerland), 1986, Volume: 4, Issue:4

    Topics: Acute Disease; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hypertension,

1986
[Current views on non-invasive treatment of hemorrhaging esophageal varices].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1988, Apr-04, Volume: 43, Issue:14

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemostatic Techniques; Humans; Proprano

1988
[Sclerotherapy of esophageal varices using ethanol in combination with propranolol: clinical study of 30 patients].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:12

    Topics: Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; Ethanol; Female; Gastrointestinal H

1988
The medical prevention of variceal bleeding.
    Intensive care medicine, 1988, Volume: 14, Issue:2

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1988
Management of the patient with hemorrhaging esophageal varices.
    JAMA, 1986, Sep-19, Volume: 256, Issue:11

    Topics: Airway Obstruction; Catheterization; Esophageal and Gastric Varices; Fluid Therapy; Gastrointestinal

1986
Ideal treatment of portal hypertension in 1985.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Acute Disease; Clinical Trials as Topic; Double-Blind Method; Endoscopy; Esophageal and Gastric Vari

1985

Trials

138 trials available for propranolol and Esophageal Varices

ArticleYear
Propranolol vs. band ligation for primary prophylaxis of variceal hemorrhage in cirrhotic patients with ascites: a randomized controlled trial.
    Hepatology international, 2022, Volume: 16, Issue:4

    Topics: Acute Kidney Injury; Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; L

2022
5-MTHF enhances the portal pressure reduction achieved with propranolol in patients with cirrhosis: A randomized placebo-controlled trial.
    Journal of hepatology, 2023, Volume: 79, Issue:4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

2023
Comparison of carvedilol and propranolol for primary prophylaxis of esophageal variceal bleed in cirrhotic patients.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:3

    Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage

2023
Small-Diameter Transjugular Intrahepatic Portosystemic Shunt versus Endoscopic Variceal Ligation Plus Propranolol for Variceal Rebleeding in Advanced Cirrhosis.
    Radiology, 2023, Volume: 308, Issue:2

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male;

2023
Hepatic venous pressure gradient-guided laparoscopic splenectomy and pericardial devascularisation versus endoscopic therapy for secondary prophylaxis for variceal rebleeding in portal hypertension (CHESS1803): study protocol of a multicenter randomised c
    BMJ open, 2020, 06-23, Volume: 10, Issue:6

    Topics: China; Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Human

2020
Covered TIPS versus endoscopic band ligation plus propranolol for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: a randomised controlled trial.
    Gut, 2018, Volume: 67, Issue:12

    Topics: Adult; Combined Modality Therapy; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastroi

2018
Efficacy of carvedilol versus propranolol versus variceal band ligation for primary prevention of variceal bleeding.
    Hepatology international, 2018, Volume: 12, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Egypt; Esophageal and Gastric Vari

2018
PORTAL HYPERTENSION TREATMENT WITH CANDESARTAN PLUS PROPRANOLOL FOR NINE MONTHS RESTORES NORMAL PORTAL CIRCULATION HEMODYNAMIC PATTERN.
    Journal of the Egyptian Society of Parasitology, 2016, Volume: 46, Issue:3

    Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Ther

2016
Measurement of variceal pressure with a computerized endoscopic manometry: validation and effect of propranolol therapy in cirrhotic patients.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adult; Antihypertensive Agents; Esophageal and Gastric Varices; Esophagoscopes; Esophagoscopy; Femal

2013
Effects of the adjunctive probiotic VSL#3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:8

    Topics: Adult; Analysis of Variance; Anti-Bacterial Agents; Biomarkers; Chi-Square Distribution; Combined Mo

2013
Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis.
    World journal of gastroenterology, 2013, Jul-14, Volume: 19, Issue:26

    Topics: Adult; China; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal He

2013
Endoscopic ultrasonography assessment of para-esophageal varices predicts efficacy of propranolol in preventing recurrence of esophageal varices.
    Journal of gastroenterology, 2015, Volume: 50, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Endosonography; Esophageal and Gastric Var

2015
Propranolol associated with endoscopic band ligation reduces recurrence of esophageal varices for primary prophylaxis of variceal bleeding: a randomized-controlled trial.
    European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophage

2015
Advanced Cirrhosis Combined with Portal Vein Thrombosis: A Randomized Trial of TIPS versus Endoscopic Band Ligation Plus Propranolol for the Prevention of Recurrent Esophageal Variceal Bleeding.
    Radiology, 2015, Volume: 276, Issue:1

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophageal and

2015
Prevention of Rebleeding From Esophageal Varices in Patients With Cirrhosis Receiving Small-Diameter Stents Versus Hemodynamically Controlled Medical Therapy.
    Gastroenterology, 2015, Volume: 149, Issue:3

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gast

2015
A Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy of Carvedilol vs. Propranolol to Reduce Portal Pressure in Patients With Liver Cirrhosis.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:11

    Topics: Adult; Antihypertensive Agents; Ascites; Carbazoles; Carvedilol; End Stage Liver Disease; Esophageal

2016
Carvedilol versus propranolol effect on hepatic venous pressure gradient at 1 month in patients with index variceal bleed: RCT.
    Hepatology international, 2017, Volume: 11, Issue:2

    Topics: Adult; Antihypertensive Agents; Carbazoles; Carvedilol; Esophageal and Gastric Varices; Esophagoscop

2017
Acute hemodynamic response to beta-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding.
    Gastroenterology, 2009, Volume: 137, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrha

2009
Propranolol, isosorbide mononitrate and endoscopic band ligation - alone or in varying combinations for the prevention of esophageal variceal rebleeding.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009, Volume: 19, Issue:5

    Topics: Adult; Aged; Combined Modality Therapy; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal

2009
Addition of propranolol and isosorbide mononitrate to endoscopic variceal ligation does not reduce variceal rebleeding incidence.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Adult; Combined Modality Therapy; Endoscopy, Digestive System; Esophageal and Gastric Varices; Femal

2009
Acute and chronic hemodynamic changes after propranolol in patients with cirrhosis under primary and secondary prophylaxis of variceal bleeding: a pilot study.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:5

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Follow-Up

2010
Equal efficacy of endoscopic variceal ligation and propranolol in preventing variceal bleeding in patients with noncirrhotic portal hypertension.
    Gastroenterology, 2010, Volume: 139, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Child; Child, Preschool; Esophageal and Gastric Vari

2010
Endoscopic cyanoacrylate injection versus beta-blocker for secondary prophylaxis of gastric variceal bleed: a randomised controlled trial.
    Gut, 2010, Volume: 59, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Child; Cyanoacrylates; Embolization, Therapeut

2010
Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial.
    Journal of hepatology, 2011, Volume: 54, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Child; Cyanoacrylates; Esophageal and Gastric

2011
Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial.
    Journal of hepatology, 2011, Volume: 54, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Child; Cyanoacrylates; Esophageal and Gastric

2011
Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial.
    Journal of hepatology, 2011, Volume: 54, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Child; Cyanoacrylates; Esophageal and Gastric

2011
Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: a randomized controlled trial.
    Journal of hepatology, 2011, Volume: 54, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Child; Cyanoacrylates; Esophageal and Gastric

2011
[Comparison of endoscopic band ligation and propranolol for the primary prophylaxis of variceal bleeding in cirrhosis].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2012, Volume: 37, Issue:5

    Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrha

2012
Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol.
    Gut, 2013, Volume: 62, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Dose-Response Relationship, Drug;

2013
Endoscopic variceal ligation plus propranolol vs. transjugular intrahepatic portosystemic stent shunt: a long-term randomized trial.
    Endoscopy, 2002, Volume: 34, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Esophageal and Gastric Varices; Female; Hepatic Encephalop

2002
Primary prophylaxis of variceal hemorrhage: a randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate.
    Gastroenterology, 2002, Volume: 123, Issue:3

    Topics: Antihypertensive Agents; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastroin

2002
A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis.
    Gastroenterology, 2002, Volume: 123, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Endoscopy; Esophageal and Gastric Varices; Female; Follow-

2002
Long term effects of propranolol on portal pressure in cirrhotic patients.
    Romanian journal of gastroenterology, 2003, Volume: 12, Issue:1

    Topics: Antihypertensive Agents; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemody

2003
Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: a double-blind RCT.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Esophageal

2003
Portal pressure response to losartan compared with propranolol in patients with cirrhosis.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Esophageal and Gastric

2003
Endoscopic histoacryl obliteration vs. propranolol in the prevention of esophagogastric variceal rebleeding: a randomized trial.
    Endoscopy, 2003, Volume: 35, Issue:9

    Topics: Adult; Aged; Antihypertensive Agents; Enbucrilate; Endoscopy; Esophageal and Gastric Varices; Female

2003
Cirrhosis and bleeding: the need for very early management.
    Journal of hepatology, 2003, Volume: 39, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ascites; Double-Blind Method; Esophageal and Gastric Varic

2003
Effect of propranolol and depot lanreotide SR on postprandial and circadian portal haemodynamics in cirrhosis.
    Alimentary pharmacology & therapeutics, 2003, Oct-15, Volume: 18, Issue:8

    Topics: Antihypertensive Agents; Circadian Rhythm; Delayed-Action Preparations; Esophageal and Gastric Varic

2003
Propranolol alone may not be acceptable to prevent first esophageal variceal bleeding in Japanese cirrhotic patients: randomized controlled trial.
    Journal of gastroenterology and hepatology, 2004, Volume: 19, Issue:5

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu

2004
Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:1

    Topics: Actuarial Analysis; Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Esophagus; Female;

2004
A randomized controlled trial of beta-blockers versus endoscopic band ligation for primary prophylaxis: a large sample size is required to show a difference in bleeding rates.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:2

    Topics: Adrenergic beta-Antagonists; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; He

2005
Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Cause of Death; Combined Modality Therapy; Esophageal and Gastri

2005
Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices.
    Gastroenterology, 2005, Volume: 128, Issue:4

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu

2005
Variceal band ligation versus propranolol for primary prophylaxis of variceal bleeding in cirrhosis.
    Current gastroenterology reports, 2005, Volume: 7, Issue:3

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hem

2005
Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: comparison of cirrhotic and noncirrhotic patients.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:8

    Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Endoscopy, Digestive System; Esophageal a

2005
Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: a randomized controlled trial.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:10

    Topics: Adrenergic beta-Antagonists; Aged; Cause of Death; Epidemiologic Methods; Esophageal and Gastric Var

2005
Endoscopic sclerotherapy of oesophageal varices due to hepatosplenic schistosomiasis. A randomized controlled trial evaluating the effect of adjuvant propranolol therapy.
    Journal of the Egyptian Society of Parasitology, 2005, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Chemotherapy, Adjuvant; Esophageal and Gastric Varices; Female; Humans; Mal

2005
Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:2

    Topics: Adrenergic beta-Antagonists; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Fo

2006
Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices.
    Vascular pharmacology, 2006, Volume: 44, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alcohol Drinking; Cyclic A

2006
Octreotide enhances portal pressure reduction induced by propranolol in cirrhosis: a randomized, controlled trial.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:10

    Topics: Adrenergic beta-Antagonists; Drug Administration Schedule; Esophageal and Gastric Varices; Female; F

2007
Hemodynamic effects of propranolol with spironolactone in patients with variceal bleeds: a randomized controlled trial.
    World journal of gastroenterology, 2008, Mar-28, Volume: 14, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Diuretics; Drug Therapy, Combination; Esophageal and Gastric Var

2008
Propranolol--a medical treatment for portal hypertension?
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Administration, Oral; Cardiac Output; Clinical Trials as Topic; Esophageal and Gastric Varices; Gast

1980
Propranolol in prevention of recurrent gastrointestinal bleeding in cirrhotic patients.
    Lancet (London, England), 1981, Apr-25, Volume: 1, Issue:8226

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Humans; Liver Cirrhosis; Peptic Ulcer Hemo

1981
[Beta blocker prevention of hemorrhages from esophageal varices in liver cirrhosis].
    Deutsche medizinische Wochenschrift (1946), 1983, Apr-08, Volume: 108, Issue:14

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Clinical Trials as Topic; Esophageal and Gastric Varice

1983
Controlled trial of propranolol for the prevention of recurrent variceal hemorrhage in patients with cirrhosis.
    The New England journal of medicine, 1983, Dec-22, Volume: 309, Issue:25

    Topics: Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemo

1983
What to do about esophageal varices?
    The New England journal of medicine, 1983, Dec-22, Volume: 309, Issue:25

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propr

1983
Propranolol and haemorrhage due to rupture of oesophageal varices.
    Hepato-gastroenterology, 1984, Volume: 31, Issue:6

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hyper

1984
Treatment of bleeding varices: controversy and opportunity.
    Hospital practice (Office ed.), 1984, Volume: 19, Issue:4

    Topics: Clinical Trials as Topic; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestina

1984
Gastrointestinal bleeding after abrupt cessation of propranolol administration in cirrhosis.
    The New England journal of medicine, 1982, Aug-26, Volume: 307, Issue:9

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Propranolol; S

1982
Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study.
    The New England journal of medicine, 1981, Dec-03, Volume: 305, Issue:23

    Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female;

1981
Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis.
    Lancet (London, England), 1995, Oct-21, Volume: 346, Issue:8982

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal

1995
Prevention of rebleeding from oesophageal varices: two-year follow up of a prospective controlled trial of propranolol in addition to sclerotherapy.
    Journal of hepatology, 1994, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Pressure; Combined Modality Therapy; Esophageal and Gastric Varices;

1994
Propranolol reduces mortality in patients with portal hypertension secondary to schistosomiasis.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:5

    Topics: Adult; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hum

1994
Beta-adrenergic antagonists to prevent bleeding from esophageal varices: a risk during liver transplantation?
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Adult; Cardiac Output; Esophageal and Gastric Varices; Female; Heart Rate; Hemorrhage; Humans; Liver

1994
Duplex Doppler ultrasonographic comparison of the effects of propranolol and isosorbide-5-mononitrate on portal hemodynamics.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1993, Volume: 12, Issue:9

    Topics: Delayed-Action Preparations; Double-Blind Method; Drug Monitoring; Esophageal and Gastric Varices; F

1993
Effect of propranolol on prevention of first variceal bleed and survival in patients with chronic liver disease.
    Alimentary pharmacology & therapeutics, 1994, Volume: 8, Issue:1

    Topics: Adult; Aged; Child; Child, Preschool; Chronic Disease; Double-Blind Method; Esophageal and Gastric V

1994
Propranolol versus sclerotherapy in preventing variceal rebleeding: a randomized controlled trial.
    Gastroenterology, 1993, Volume: 105, Issue:5

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged

1993
Reduction of variceal pressure by propranolol: comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1993, Volume: 18, Issue:5

    Topics: Adult; Aged; Azygos Vein; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointesti

1993
[Prevention of digestive hemorrhage recurrence in hepatic cirrhosis with propranolol. A 4 years' follow-up study].
    Revista medica de Chile, 1993, Volume: 121, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastroint

1993
[Propranolol for prophylaxis of first hemorrhage in cirrhotic patients with esophageal varices--a controlled study comparing with sclerotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1993, Volume: 90, Issue:9

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis;

1993
Effects of propranolol compared with clonidine on portal haemodynamics: a double-blind cross-over study using duplex-Doppler ultrasonography.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:9

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Blood Flow Velocity; Blood Pressure; Clonidine; Cro

1995
The effect of long-term treatment with spironolactone on variceal pressure in patients with portal hypertension without ascites.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Ascites; Atrial Natriuretic Factor;

1996
Sclerotherapy versus sclerotherapy and propranolol in the prevention of rebleeding from oesophageal varices: a randomised study.
    Gut, 1996, Volume: 38, Issue:5

    Topics: Adult; Aged; Antihypertensive Agents; Combined Modality Therapy; Esophageal and Gastric Varices; Fem

1996
Measurement of variceal pressure with an endoscopic pressure sensitive gauge: validation and effect of propranolol therapy in chronic conditions.
    Journal of hepatology, 1996, Volume: 24, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Endoscopy; Esophageal and Gastric Var

1996
Non-invasive variceal pressure measurements: validation and clinical implications.
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1996, Volume: 58, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure Determination; Double-Blind Method; Esophageal

1996
Prevention of recurrent esophageal bleeding and survival in patients with alcoholic cirrhosis: a randomized study.
    Puerto Rico health sciences journal, 1996, Volume: 15, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Esophageal and Gastric Varices; Female; Gastrointestinal Hemor

1996
Randomised trial of transjugular-intrahepatic-portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding.
    Lancet (London, England), 1997, Apr-12, Volume: 349, Issue:9058

    Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Embolization, Therapeutic; Endoscopy; Eso

1997
Transjugular intrahepatic portosystemic stent shunt versus sclerotherapy plus propranolol for variceal rebleeding.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Adult; Aged; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage;

1997
Endoscopic assessment of variceal volume and wall tension in cirrhotic patients: effects of pharmacological therapy.
    Gastroenterology, 1997, Volume: 113, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Endosonography; Esophageal and Gastri

1997
Duplex-Doppler evaluation of the effects of propranolol and isosorbide-5-mononitrate on portal flow and splanchnic arterial circulation in cirrhosis.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Esophageal and Gastric Varices; Female; Hu

1998
Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding.
    The New England journal of medicine, 1999, Apr-01, Volume: 340, Issue:13

    Topics: Adrenergic beta-Antagonists; Adult; Endoscopy; Esophageal and Gastric Varices; Female; Gastrointesti

1999
Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastr

1999
Carvedilol, a new nonselective beta-blocker with intrinsic anti- Alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure;

1999
Propranolol in prevention of portal hypertensive hemorrhage in children: a pilot study.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 29, Issue:1

    Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Esophageal and Gastric Varices; Female

1999
Lack of effect of propranolol in the prevention of large oesophageal varices in patients with cirrhosis: a randomized trial. French-Speaking Club for the Study of Portal Hypertension.
    European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Esophageal and Gastric Varices; Femal

1999
[Primary prevention of esophageal variceal rupture: endoscopic ligation or propranolol?].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Endoscopy, Digestive System; Esophageal and Gastric Varices; Fol

1999
Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Drug Synergism; Drug Therapy, Combination; Esophageal and Gastric

2000
Endoscopic sclerotherapy plus propranolol versus propranolol alone in the primary prevention of bleeding in high risk cirrhotic patients with esophageal varices: a prospective multicenter randomized trial.
    Gastrointestinal endoscopy, 2000, Volume: 51, Issue:6

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Esophagoscopy; Female; Follow-Up Studie

2000
[A randomized controlled study of ligustrazine in combination with propranolol for prevention of recurrent esophageal varices bleeding].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2000, Volume: 8, Issue:2

    Topics: Adult; Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal Hem

2000
Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding.
    Gastrointestinal endoscopy, 2000, Volume: 51, Issue:5

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Esophagoscopy; Follow-Up Studies; Gastr

2000
Daily variation of azygos and portal blood flow and the effect of propranolol administration once an evening in cirrhotics.
    Journal of hepatology, 2001, Volume: 34, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Azygos Vein; Esophageal and Gastric Varices; Female; Gastrointest

2001
The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial.
    Gastrointestinal endoscopy, 2001, Volume: 53, Issue:6

    Topics: Adult; Aged; Combined Modality Therapy; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices;

2001
Propranolol for the prevention of first esophageal variceal hemorrhage: a lifetime commitment?
    Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:6

    Topics: Adrenergic beta-Antagonists; Double-Blind Method; Drug Administration Schedule; Esophageal and Gastr

2001
Acute and 7-day portal pressure response to carvedilol and propranolol in cirrhotics.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbazole

2002
Should neither sclerotherapy nor propranolol be used prophylactically for oesophageal varices?
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1992, Volume: 6, Issue:2

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Live

1992
Endoscopic sclerotherapy versus propranolol in prevention of recurrent variceal bleeding in patients with child's B and C cirrhosis: a preliminary report.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1992, Volume: 11, Issue:2

    Topics: Adult; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis;

1992
Beta-blockers and prevention of first variceal hemorrhage: tantalizing expectations?
    The American journal of gastroenterology, 1992, Volume: 87, Issue:12

    Topics: Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Ma

1992
Factors associated with failure of propranolol for the prevention of first bleeding in cirrhotic patients. The Study Group of Primary Prophylaxis.
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:6-7

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Incidence; Liver Cirrhosis; Liv

1992
Propranolol reduces the rebleeding rate during endoscopic sclerotherapy before variceal obliteration.
    Gastroenterology, 1992, Volume: 102, Issue:5

    Topics: Adult; Aged; Esophageal and Gastric Varices; Esophagoscopy; Female; Gastrointestinal Hemorrhage; Hum

1992
Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials. Franco-Italian Multicenter
    The New England journal of medicine, 1991, May-30, Volume: 324, Issue:22

    Topics: Adrenergic beta-Antagonists; Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemor

1991
Beta-Blocker therapy for prophylaxis of initial variceal hemorrhage: has its time come?
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:1

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Hemodynamics; Hemorrhage; Humans; Propr

1991
[Prevention of recurrent hemorrhage in patients with cirrhosis. Results of a controlled trial of propranolol versus endoscopic sclerotherapy].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:11

    Topics: Actuarial Analysis; Adult; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Foll

1991
[Prospective controlled study of elective sclerotherapy plus oral propranolol for prevention of recurrent bleeding in cirrhotics with recent variceal hemorrhage].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1991, Volume: 88, Issue:6

    Topics: Administration, Oral; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hepatic Veins; Hu

1991
Prevention of recurrent variceal bleeding in alcoholic cirrhotic patients: prospective controlled trial of propranolol and sclerotherapy.
    Journal of hepatology, 1991, Volume: 12, Issue:3

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemor

1991
Long-term effects of oral propranolol on splanchnic and systemic haemodynamics in patients with cirrhosis and oesophageal varices.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:9

    Topics: Administration, Oral; Biopsy; Catheterization, Peripheral; Esophageal and Gastric Varices; Follow-Up

1991
Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients: a randomized multicenter trial. The PROVA Study Group.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:6

    Topics: Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Inci

1991
[Primary prevention of digestive hemorrhages in cirrhotic patients].
    Annales de gastroenterologie et d'hepatologie, 1990, Volume: 26, Issue:5

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Li

1990
Prophylaxis for variceal bleeding.
    Gastroenterology, 1991, Volume: 100, Issue:6

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Propranolol; S

1991
Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. The Boston-New Haven-Barcelona Portal Hypertension Study Group.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:5

    Topics: Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorr

1991
Double-blind investigation of the effects of propranolol and placebo on the pressure of esophageal varices in patients with portal hypertension.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:5

    Topics: Adult; Aged; Blood Pressure; Blood Pressure Determination; Double-Blind Method; Esophageal and Gastr

1991
A controlled trial of oral propranolol compared with injection sclerotherapy for the long-term management of variceal bleeding.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:3

    Topics: Administration, Oral; Blood Pressure; Clinical Trials as Topic; Esophageal and Gastric Varices; Fema

1990
Prevention of recurrent variceal hemorrhage: to block or not to block?
    The American journal of gastroenterology, 1990, Volume: 85, Issue:5

    Topics: Atenolol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Prop

1990
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage.
    Gastroenterology, 1990, Volume: 99, Issue:5

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointe

1990
Preventive therapy of first gastrointestinal bleeding in patients with cirrhosis: results of a controlled trial comparing propranolol, endoscopic sclerotherapy and placebo.
    Hepatology (Baltimore, Md.), 1990, Volume: 12, Issue:6

    Topics: Esophageal and Gastric Varices; Esophagoscopy; Female; Follow-Up Studies; Gastrointestinal Hemorrhag

1990
Evaluation of propranolol for prevention of recurrent bleeding from esophageal varices between sclerotherapy sessions.
    Acta chirurgica Scandinavica, 1990, Volume: 156, Issue:10

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Prop

1990
Efficacy of oral propranolol and injection sclerotherapy in the long-term management of variceal bleeding.
    Digestion, 1990, Volume: 46, Issue:4

    Topics: Administration, Oral; Adult; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hu

1990
Propranolol may prevent recurrence of oesophageal varices after obliteration by endoscopic sclerotherapy.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:4

    Topics: Adult; Aged; Combined Modality Therapy; Double-Blind Method; Esophageal and Gastric Varices; Esophag

1990
Propranolol in the prevention of recurrent variceal hemorrhage in cirrhotic patients. A controlled trial.
    Gastroenterology, 1990, Volume: 98, Issue:1

    Topics: Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Li

1990
Controlled trial of propranolol to prevent recurrent variceal bleeding in patients with non-cirrhotic portal fibrosis.
    BMJ (Clinical research ed.), 1989, May-20, Volume: 298, Issue:6684

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Vari

1989
[Prevention of recurrent hemorrhage caused by the rupture of esophageal varices in cirrhotic patients. A controlled study of propranolol and clip ligation of the esophagus].
    Presse medicale (Paris, France : 1983), 1989, Oct-28, Volume: 18, Issue:35

    Topics: Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Esophagus; Female; Gastrointe

1989
Beta-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis: a multicenter randomized controlled trial.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:3

    Topics: Actuarial Analysis; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Atenolol; Clinical Trials a

1989
Randomized controlled study of propranolol for prevention of recurrent esophageal varices bleeding in patients with cirrhosis.
    Liver, 1989, Volume: 9, Issue:1

    Topics: Adult; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage

1989
Propranolol in prevention of rebleeding from oesophageal varices during the course of endoscopic sclerotherapy.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:3

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Esophageal and Gastric Varices; Esophago

1989
Propranolol in the primary prevention of upper gastrointestinal tract haemorrhage in patients with cirrhosis of the liver and oesophageal varices.
    Drugs, 1989, Volume: 37 Suppl 2

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis;

1989
[Propranolol in the prevention of digestive bleeding in cirrhotic patients].
    Acta gastroenterologica Latinoamericana, 1989, Volume: 19, Issue:1

    Topics: Blood Pressure; Cardiac Output; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Ga

1989
Comparison of three nonsurgical treatments for bleeding esophageal varices.
    Gastroenterology, 1989, Volume: 96, Issue:3

    Topics: Blood Transfusion; Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscopy; Ethanol

1989
Comparison of treatments of bleeding varices: effects of differences between treatment intended and treatment received.
    Hepatology (Baltimore, Md.), 1989, Volume: 10, Issue:4

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhag

1989
Comparison of propranolol with injection sclerotherapy in prevention of rebleeding from oesophageal varices in cirrhotic patients.
    Drugs, 1989, Volume: 37 Suppl 2

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male;

1989
Sclerotherapy versus propranolol after first variceal haemorrhage in alcoholic cirrhosis.
    Lancet (London, England), 1985, Jul-13, Volume: 2, Issue:8446

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis, Alcoholic; Pro

1985
[Pharmacological therapy of portal hypertension].
    Schweizerische medizinische Wochenschrift, 1985, Oct-19, Volume: 115, Issue:42

    Topics: Acute Disease; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Esophageal an

1985
Drug therapy for portal hypertension.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Animals; Clinical Trials as Topic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemo

1986
[Beta-receptor blockaders in the prevention of hemorrhaging of esophageal varices?].
    Deutsche medizinische Wochenschrift (1946), 1987, Aug-14, Volume: 112, Issue:33

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Drug Evaluation; Esophageal and Gastric Varic

1987
Propranolol or endoscopic sclerotherapy in the prevention of recurrence of variceal bleeding. A prospective, randomized controlled trial.
    Journal of hepatology, 1988, Volume: 7, Issue:2

    Topics: Adult; Clinical Trials as Topic; Endoscopy; Esophageal and Gastric Varices; Female; Follow-Up Studie

1988
Prediction of variceal hemorrhage: a prospective study.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:5

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhag

1988
[Endoscopic sclerotherapy versus propranolol after hemorrhage caused by rupture of esophageal varices in patients with cirrhosis. Results of a 4-year randomized study].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:3

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male;

1988
Reduction in early recurrence of variceal bleeding by propranolol.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:3

    Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastro

1988
Propranolol in the prevention of first upper gastrointestinal tract hemorrhage in patients with cirrhosis of the liver and esophageal varices.
    The New England journal of medicine, 1987, Oct-01, Volume: 317, Issue:14

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastrointestina

1987
Systemic and hepatic hemodynamics after variceal hemorrhage: effects of propranolol and placebo.
    Gastroenterology, 1987, Volume: 93, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemo

1987
[Controlled study of propranolol in the prevention of recurrent hemorrhage in cirrhotic patients].
    Gastroenterologie clinique et biologique, 1987, Volume: 11, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointe

1987
Prevention of recurrent variceal bleeding: non-surgical procedures.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Humans; Liver Circulation; Liver C

1985
Ideal treatment of portal hypertension in 1985.
    Clinics in gastroenterology, 1985, Volume: 14, Issue:1

    Topics: Acute Disease; Clinical Trials as Topic; Double-Blind Method; Endoscopy; Esophageal and Gastric Vari

1985

Other Studies

140 other studies available for propranolol and Esophageal Varices

ArticleYear
Carvedilol as secondary prophylaxis for variceal bleeding in hepatosplenic schistosomiasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022, 07-06, Volume: 116, Issue:7

    Topics: Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Ligation; Propranol

2022
Blunted cardiovascular effects of beta-blockers in patients with cirrhosis: Relation to severity?
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Li

2022
Acute hemodynamic response to propranolol predicts bleeding and nonbleeding decompensation in patients with cirrhosis.
    Hepatology communications, 2022, Volume: 6, Issue:9

    Topics: Adult; Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Live

2022
Carvedilol Achieves Higher Hemodynamic Response and Lower Rebleeding Rates Than Propranolol in Secondary Prophylaxis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2023, Volume: 21, Issue:9

    Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage

2023
KASL clinical practice guidelines for liver cirrhosis: Varices, hepatic encephalopathy, and related complications.
    Clinical and molecular hepatology, 2020, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Ammonia; Anti-Bacterial Agents; Carvedilol; Disaccharides; Endoscopy, G

2020
Propranolol plus endoscopic ligation for variceal bleeding in patients with significant ascites: Propensity score matching analysis.
    Medicine, 2020, Volume: 99, Issue:5

    Topics: Adrenergic beta-Antagonists; Ascites; Combined Modality Therapy; Endoscopy; Esophageal and Gastric V

2020
The Effect of Liraglutide on β-Blockade for Preventing Variceal Bleeding: A Case Series.
    Annals of internal medicine, 2020, 09-01, Volume: 173, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Diabetes Mellitus, Type 2; Drug Interactions; Esophageal and Gast

2020
Diagnosis and management of extrahepatic oesophageal variceal bleed in children in a low resourced setting.
    Ghana medical journal, 2020, Volume: 54, Issue:4

    Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Esophageal and Gastric Varices; Female;

2020
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
    Wiener klinische Wochenschrift, 2017, Volume: 129, Issue:Suppl 3

    Topics: Austria; Carbazoles; Carvedilol; Comorbidity; Early Medical Intervention; Esophageal and Gastric Var

2017
Primary prophylaxis of variceal bleeding.
    Hepatology international, 2018, Volume: 12, Issue:1

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Endoscopy; Esophageal and Gastric Varices; Gast

2018
Pregnancy in a patient with portal hypertension secondary to liver cirrhosis.
    BMJ case reports, 2018, Mar-05, Volume: 2018

    Topics: Adult; Antihypertensive Agents; Cardiotocography; Esophageal and Gastric Varices; Female; Gastrointe

2018
Dose-dependent effect of propranolol on the hemodynamic response in cirrhotic patients with gastroesophageal varices.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Databases, Factual; Dose-Response Relationship, Drug; Esop

2019
Transjugular intrahepatic portosystemic shunt prevents rebleeding in cirrhotic patients having cavernous transformation of the portal vein without improving their survival.
    Journal of digestive diseases, 2019, Volume: 20, Issue:2

    Topics: Adult; Aged; Antihypertensive Agents; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gas

2019
Liver volume index predicts the risk of esophageal variceal hemorrhage in cirrhotic patients on propranolol prophylaxis.
    The Korean journal of internal medicine, 2019, Volume: 34, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Decision Support Techniques; Esophageal and Gastric Varice

2019
Impact of non-selective beta blockers on portal hypertension and hepatic elasticity in hepatitis C virus-related liver cirrhosis.
    Drug discoveries & therapeutics, 2019, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Case-Control Studies; Disease Progression; Elasticity Imaging Technique

2019
The secondary prophylactic efficacy of beta-blocker after endoscopic gastric variceal obturation for first acute episode of gastric variceal bleeding.
    Clinical and molecular hepatology, 2013, Volume: 19, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Enbucrilate; Endoscopy, Digestive System; Esophageal and G

2013
The comparison of esophageal variceal ligation plus propranolol versus propranolol alone for the primary prophylaxis of esophageal variceal bleeding.
    Clinical and molecular hepatology, 2014, Volume: 20, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Esophageal and Gastric Varices; Female; Follow-Up Studies;

2014
Extrahepatic portal vein obstruction in Egyptian children.
    Journal of pediatric gastroenterology and nutrition, 2015, Volume: 60, Issue:1

    Topics: Child; Child, Preschool; Cohort Studies; Diagnosis, Differential; Egypt; Esophageal and Gastric Vari

2015
β-2 Adrenergic receptor gene polymorphism and response to propranolol in cirrhosis.
    World journal of gastroenterology, 2015, Jun-21, Volume: 21, Issue:23

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Case-Control Studies; Esophageal and Gastric V

2015
Integrity of Data in a Randomized Controlled Trial.
    Radiology, 2015, Volume: 276, Issue:3

    Topics: Adrenergic beta-Antagonists; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hu

2015
Influence of CYP2D6 and β2-adrenergic receptor gene polymorphisms on the hemodynamic response to propranolol in Chinese Han patients with cirrhosis.
    Journal of gastroenterology and hepatology, 2016, Volume: 31, Issue:4

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Asian People; Cytochrome P-450 CYP2D6; Esophageal

2016
Response.
    Radiology, 2015, Volume: 276, Issue:3

    Topics: Adrenergic beta-Antagonists; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Female; Hu

2015
Successful pregnancy with autoimmune cirrhosis.
    BMJ case reports, 2016, Jan-29, Volume: 2016

    Topics: Adrenal Cortex Hormones; Adult; Antihypertensive Agents; Azathioprine; Cesarean Section; Esophageal

2016
Red signs and not severity of cirrhosis should determine non-selective β-blocker treatment in Child-Pugh C cirrhosis with small varices: increased risk of hepatorenal syndrome and death beyond 6 months of propranolol use.
    Gut, 2016, Volume: 65, Issue:7

    Topics: Adrenergic beta-Antagonists; Ascites; Child; Esophageal and Gastric Varices; Hepatorenal Syndrome; H

2016
Second prophylaxis of variceal bleeding in cirrhotic patients with a high HVPG.
    Scandinavian journal of gastroenterology, 2016, Volume: 51, Issue:12

    Topics: Adult; Aged; China; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hepatic Enc

2016
The anti-inflammatory role of propranolol in cirrhosis: Preventing the inflammatory exhaustion?
    Journal of hepatology, 2017, Volume: 66, Issue:1

    Topics: Anti-Inflammatory Agents; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cirrho

2017
Risk and Predictors of Variceal Bleeding in Cirrhosis Patients Receiving Primary Prophylaxis With Non-Selective Beta-Blockers.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:12

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Ascites; Cohort Studies; Comorbidity; Dose-Response

2016
Secondary prophylaxis for variceal bleeding: carvedilol vs. propranolol.
    Hepatology international, 2017, Volume: 11, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Carvedilol; Drug Monitoring; Esophageal and

2017
Early propranolol administration does not prevent development of esophageal varices in cirrhotic rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2009, Volume: 42, Issue:1

    Topics: Animals; Carbon Tetrachloride; Esophageal and Gastric Varices; Hypertension, Portal; Liver Cirrhosis

2009
Early identification of haemodynamic response to pharmacotherapy is essential for primary prophylaxis of variceal bleeding in patients with 'high-risk' varices.
    Alimentary pharmacology & therapeutics, 2009, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Esophageal and Gastric Varices; Female;

2009
Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Endosonography; Esophageal and Gastric Varices; Esophag

2009
Oral propranolol decreases intestinal permeability in patients with cirrhosis: another protective mechanism against bleeding?
    The American journal of gastroenterology, 2009, Volume: 104, Issue:12

    Topics: Adrenergic beta-Antagonists; Bacterial Translocation; Clinical Trials as Topic; Esophageal and Gastr

2009
Beta-blockers in cirrhosis: friend and foe?
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:3

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Humans; Liver Cirrhosis; Peritonitis; P

2010
A specialized, nurse-run titration clinic: a feasible option for optimizing beta-blockade in non-clinical trial patients.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:9

    Topics: Adrenergic beta-Antagonists; Ambulatory Care Facilities; Esophageal and Gastric Varices; Female; Gas

2010
[Beta-blockers in portal hypertension: Unexpected limitations!].
    Presse medicale (Paris, France : 1983), 2011, Volume: 40, Issue:3

    Topics: Adrenergic beta-Antagonists; Cause of Death; Esophageal and Gastric Varices; Esophagoscopy; Gastroin

2011
Effects of beta-blockers on survival for patients with cirrhosis and refractory ascites.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Ascites; Contraindications; Esophageal and Gastric Varices; Gastrointes

2011
Evening administration of long-acting beta-blockers for primary prophylaxis in cirrhosis: an effective strategy.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:3

    Topics: Adrenergic beta-Antagonists; Delayed-Action Preparations; Drug Administration Schedule; Esophageal a

2011
Non-selective β-blockers improve the correlation of liver stiffness and portal pressure in advanced cirrhosis.
    Journal of gastroenterology, 2012, Volume: 47, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Carbazoles; Carvedilol; Elasticity; Elasticity Imaging Technique

2012
Portal hypertension in children.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Child; Endoscopy, Digestive System; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Li

2012
Successful pregnancy in a woman with liver cirrhosis complicated by recurrent variceal bleeding.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2012, Volume: 32, Issue:5

    Topics: Adult; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Gestational Age; Humans;

2012
Endoscopic and pharmacological secondary prophylaxis in children and adolescents with esophageal varices.
    Journal of pediatric gastroenterology and nutrition, 2013, Volume: 56, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Child; Child, Preschool; Endoscopy, Gastrointestinal; Esoph

2013
Pharmacologic efficacy in gastric variceal rebleeding and survival: including multivariate analysis.
    Journal of clinical gastroenterology, 2002, Volume: 35, Issue:2

    Topics: Adrenergic beta-Antagonists; Carcinoma, Hepatocellular; Esophageal and Gastric Varices; Female; Gast

2002
Therapy for primary prophylaxis of varices: and, the winner is...?
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:2

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Hemorrhage; Humans; Isosorbide Dinitrat

2003
Optimal use of propranolol.
    Gastroenterology, 2003, Volume: 124, Issue:7

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Isosorbide Dinitrate; Ligation;

2003
Propranolol does not affect incidence of spontaneous bacterial peritonitis in cirrhotic patients with ascites.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Ascites; Bacterial Translocation; Esophageal and Gastric V

2003
Long-term outcome after sclerotherapy with or without a beta-blocker for variceal bleeding in children.
    Pediatrics international : official journal of the Japan Pediatric Society, 2003, Volume: 45, Issue:4

    Topics: Antihypertensive Agents; Child; Child, Preschool; Combined Modality Therapy; Esophageal and Gastric

2003
Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2003, Volume: 13, Issue:9

    Topics: Antihypertensive Agents; Endoscopy, Digestive System; Esophageal and Gastric Varices; Gastrointestin

2003
Management of cirrhosis and ascites.
    The New England journal of medicine, 2004, Jul-15, Volume: 351, Issue:3

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointest

2004
Reversal of portal hypertension in a patient with primary biliary cirrhosis: disappearance of esophageal varices and thrombocytopenia.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:9

    Topics: Biopsy, Needle; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Follow-Up Studies

2004
[Variceal hemorrhage: primary and secondary prophylaxis].
    Deutsche medizinische Wochenschrift (1946), 2004, Sep-03, Volume: 129 Suppl 2

    Topics: Adrenergic beta-Antagonists; Algorithms; Esophageal and Gastric Varices; Esophagoscopy; Gastrointest

2004
Can somatostatin control acute bleeding from oesophageal varices in Schistosoma mansoni patients?[ISRCTN63456799].
    BMC infectious diseases, 2004, Dec-13, Volume: 4, Issue:1

    Topics: Adolescent; Anthelmintics; Antihypertensive Agents; Child; Drug Therapy, Combination; Esophageal and

2004
Primary prophylaxis against variceal bleeding: beta-blockers, endoscopic ligation, or both?
    The American journal of gastroenterology, 2005, Volume: 100, Issue:4

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Esophageal and Gastric Varices; Esophagoscop

2005
[Hemodynamic response to a single dose of intravenous propranolol in the prophylaxis of variceal bleeding].
    Gastroenterologia y hepatologia, 2005, Volume: 28, Issue:10

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Blood Pressure; Drug Evaluation; Esophageal and G

2005
Is banding ligation for primary prevention of variceal bleeding as effective as beta-blockers, and is it safe?
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:1

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Li

2006
[Prevention of variceal bleeding and measurement of hepatic vein pressure gradient].
    The Korean journal of hepatology, 2006, Volume: 12, Issue:3

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointest

2006
Peristomal varices--life threatening or luminal?
    Annals of the Royal College of Surgeons of England, 2006, Volume: 88, Issue:5

    Topics: Aged; Esophageal and Gastric Varices; Humans; Ileostomy; Male; Postoperative Hemorrhage; Propranolol

2006
The low incidence of bacterial infections could be a protective factor against variceal bleeding per se in hemodynamic responders to propranolol.
    The American journal of gastroenterology, 2006, Volume: 101, Issue:10

    Topics: Antihypertensive Agents; Bacterial Infections; Esophageal and Gastric Varices; Gastrointestinal Hemo

2006
How to prevent varices from bleeding: shades of grey--the case for nonselective beta blockers.
    Gastroenterology, 2007, Volume: 133, Issue:6

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynami

2007
[Dutch study on the optimal treatment strategy for patients with a first or second occurrence of gastro-oesophageal variceal bleeding: the TIPS-TRUE trial].
    Nederlands tijdschrift voor geneeskunde, 2008, Mar-15, Volume: 152, Issue:11

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Humans; Ligation; Netherlands; Portasys

2008
[Therapy of bleeding esophageal varices].
    Lakartidningen, 1982, Jun-02, Volume: 79, Issue:22

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol; Somatostatin; Vaso

1982
Drug therapy of portal hypertension due to cirrhosis.
    Seminars in liver disease, 1982, Volume: 2, Issue:3

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Hypertension, Por

1982
Drug therapy of portal hypertension and oesophageal varices.
    British journal of hospital medicine, 1984, Volume: 32, Issue:1

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Propranol

1984
Recurrent bleeding and propranolol?
    Digestive diseases and sciences, 1983, Volume: 28, Issue:7

    Topics: Carcinoma, Hepatocellular; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Live

1983
[Therapy of bleeding esophageal varices].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1984, Volume: 90 Pt 1

    Topics: Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Port

1984
Precipitation of hepatic encephalopathy by propranolol in cirrhosis.
    British medical journal (Clinical research ed.), 1983, Aug-27, Volume: 287, Issue:6392

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; H

1983
Propranolol withdrawal and variceal hemorrhage.
    JAMA, 1983, Dec-09, Volume: 250, Issue:22

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension; Male; Middle Aged

1983
Effect of propranolol and sclerotherapy in bleeding esophageal varices. A case report.
    Acta chirurgica Scandinavica, 1984, Volume: 150, Issue:1

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Huma

1984
Propranolol: its role in the management of portal hypertension. The ACG Committee on FDA related matters.
    The American journal of gastroenterology, 1983, Volume: 78, Issue:2

    Topics: Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Propranolo

1983
Injection sclerotherapy of esophageal varices.
    Endoscopy, 1982, Volume: 14, Issue:4

    Topics: Endoscopy; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; L

1982
Propranolol for gastrointestinal bleeding in cirrhosis.
    The New England journal of medicine, 1982, Dec-30, Volume: 307, Issue:27

    Topics: Administration, Oral; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cir

1982
[Study of gastric mucosal lesion in portal hypertension].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1995, Volume: 92, Issue:8

    Topics: Antihypertensive Agents; Esophageal and Gastric Varices; Gastric Mucosa; Gastroscopy; Humans; Hypert

1995
[Endoscopic sclerotherapy: does propranolol reduce the risk of hemorrhagic recurrence?].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:5

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Live

1994
Shunt surgery and beta-blockers.
    Journal of hepatology, 1994, Volume: 20, Issue:1

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Humans; Hypertension, Portal; Liver Cir

1994
[Per-rectal scintigraphy of the portal system with pertechnetate TC-99M: effect of propranolol on portosystemic collateral circulation in patients with cirrhosis. Part II].
    Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 92, Issue:1

    Topics: Adult; Aged; Blood Pressure; Collateral Circulation; Esophageal and Gastric Varices; Female; Gastroi

1994
[Current therapeutic possibilities in esophageal varices].
    Praxis, 1994, Nov-15, Volume: 83, Issue:46

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemostatics; Humans; Propranolol; Scler

1994
Sclerotherapy versus propranolol after a variceal bleed.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1993, Volume: 7, Issue:2

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol; Prospective Studie

1993
Bleeding varices due to portal hypertension in sarcoidosis. Favorable effect of propranolol and prednisone.
    Chest, 1993, Volume: 103, Issue:2

    Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hype

1993
Propranolol in the control of haemorrhage from varices around a urostomy.
    British journal of urology, 1993, Volume: 71, Issue:5

    Topics: Aged; Anastomosis, Surgical; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hy

1993
Portal hypertension revisited.
    QJM : monthly journal of the Association of Physicians, 1995, Volume: 88, Issue:11

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Portasyst

1995
Fatal outcome following endoscopic fundal variceal ligation.
    Gastrointestinal endoscopy, 1996, Volume: 43, Issue:1

    Topics: Adult; Esophageal and Gastric Varices; Fatal Outcome; Gastroscopes; Gastroscopy; Humans; Male; Propr

1996
Primary prophylaxis of variceal bleeding in cirrhosis: a cost-effectiveness analysis.
    Gastroenterology, 1997, Volume: 112, Issue:2

    Topics: Cost-Benefit Analysis; Esophageal and Gastric Varices; Health Care Costs; Hemorrhage; Humans; Life E

1997
[The effect of obzidan on the central and hepatic portal hemodynamics in patients with liver cirrhosis].
    Klinichna khirurhiia, 1995, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Li

1995
Systemic and hepatic hemodynamics in hepatosplenic Manson's schistosomiasis with and without propranolol.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Esophageal and Gastric Varices; Hemodynamic

1997
TIPSS trials: design determines outcome.
    Hepatology (Baltimore, Md.), 1997, Volume: 26, Issue:5

    Topics: Clinical Trials as Topic; Endoscopy; Esophageal and Gastric Varices; Esophageal Diseases; Hemorrhage

1997
Long-term treatment of bleeding caused by portal hypertension in children.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Administration, Oral; Adult; Child; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal

1997
Clinical vs haemodynamic response to drugs in portal hypertension.
    Journal of hepatology, 1998, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Esophageal and Gastric Varices; Female; Follow-Up Studi

1998
Noninvasive endoscopic determination of intravariceal pressure in patients with portal hypertension: clinical experience with a new balloon technique.
    Endoscopy, 1998, Volume: 30, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Case-Control Studies; Endoscopy, Digestive System; Equipment D

1998
Primary prevention of bleeding from esophageal varices.
    The New England journal of medicine, 1999, Apr-01, Volume: 340, Issue:13

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage;

1999
Propranolol and portal hypertension: should kids be on the block?
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 29, Issue:1

    Topics: Antihypertensive Agents; Child; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans;

1999
Prevention of a first episode of variceal bleeding: role of duplex Doppler sonographic measurement of the acute response to beta-blockers.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 1999, Volume: 18, Issue:9

    Topics: Actuarial Analysis; Adrenergic beta-Antagonists; Blood Flow Velocity; Esophageal and Gastric Varices

1999
Multi-state models for bleeding episodes and mortality in liver cirrhosis.
    Statistics in medicine, 2000, Feb-29, Volume: 19, Issue:4

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Hemorrhag

2000
Therapeutic face-off: band ligation versus beta blockage for variceal bleeding.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:5

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage;

2000
Propranolol in primary and secondary prophylaxis of variceal bleeding among cirrhotics in India: a hemodynamic evaluation.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:8

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Dose-Response Relationship, Drug; Echocard

2000
Variceal bleeding prophylaxis: variceal banding or propranolol.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 2000, Volume: 11, Issue:6

    Topics: Adrenergic beta-Antagonists; Endoscopy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage;

2000
Beta-blocker plus nitrate for primary prophylaxis of variceal bleeding.
    Gastroenterology, 2000, Volume: 119, Issue:4

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Esophageal and Gastric Varices; Gastrointestinal Hemorr

2000
The portal flow velocity test is predictive of effective prevention of variceal bleeding.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:6

    Topics: Adrenergic beta-Antagonists; Blood Flow Velocity; Esophageal and Gastric Varices; Forecasting; Gastr

2001
Blind beta blockade.
    Hepatology (Baltimore, Md.), 2001, Volume: 34, Issue:4 Pt 1

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynami

2001
Beta-blockers in prevention of variceal hemorrhage: tantalizing expectations.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:2

    Topics: Adrenergic beta-Antagonists; Confounding Factors, Epidemiologic; Esophageal and Gastric Varices; Gas

1992
[Adrenergic beta blockade in liver cirrhosis with portal hypertension? Doppler ultrasound measurement of the short-term effect of propranolol on the portal system].
    Zeitschrift fur arztliche Fortbildung, 1992, Apr-27, Volume: 86, Issue:7-8

    Topics: Blood Flow Velocity; Esophageal and Gastric Varices; Follow-Up Studies; Gastrointestinal Hemorrhage;

1992
[Sclerosing treatment of esophageal varices].
    Acta gastroenterologica Latinoamericana, 1991, Volume: 21, Issue:2

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; L

1991
[Gastro-esophageal symptoms in cirrhosis].
    Annales de gastroenterologie et d'hepatologie, 1991, Volume: 27, Issue:3

    Topics: Aged; Endoscopy, Gastrointestinal; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Huma

1991
Treating esophageal varices prophylactically.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:11

    Topics: Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Humans; Propranolol; Scl

1991
Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage.
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol

1991
Propranolol for prophylactic treatment of a first variceal hemorrhage.
    Gastroenterology, 1991, Volume: 101, Issue:6

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol

1991
Variceal hemorrhage--to block or not to block?
    The American journal of gastroenterology, 1990, Volume: 85, Issue:6

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Pr

1990
Nonocclusive mesenteric ischemia associated with propranolol overdose: implications regarding splanchnic circulation.
    Journal of pediatric gastroenterology and nutrition, 1990, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Drug Overdose; Esophageal and Gastric Varices; Female; Humans; I

1990
Combination therapies may speed healing, reduce rebleeding of esophageal varices.
    JAMA, 1991, Jul-10, Volume: 266, Issue:2

    Topics: Combined Modality Therapy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liga

1991
Variceal bleeding and beta-blockade: permutation on the theme?
    The American journal of gastroenterology, 1990, Volume: 85, Issue:12

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol; Sclerotherapy

1990
Propranolol-induced reduction in recurrent variceal hemorrhage in schistosomiasis.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol; Recurrence; Schist

1990
[A medical treatment of esophageal varices by propranolol].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1990, Volume: 87, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Male; Mi

1990
Effect of endoscopic sclerotherapy and propranolol on the blood flow of esophageal varices.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:1

    Topics: Adult; Aged; Esophageal and Gastric Varices; Esophagoscopy; Esophagus; Female; Humans; Male; Middle

1990
Medical treatment of oesophageal varices by a long-term propranolol administration.
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 1

    Topics: Esophageal and Gastric Varices; Humans; Portal System; Propranolol

1989
Effect of propranolol on oesophageal variceal pressure in a patient with extrahepatic portal obstruction.
    Journal of gastroenterology and hepatology, 1989, Volume: 4 Suppl 1

    Topics: Blood Pressure; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Male; Middle Ag

1989
[Propranolol and the risk of hepatic encephalopathy in liver cirrhosis].
    Annales de gastroenterologie et d'hepatologie, 1989, Volume: 25, Issue:7

    Topics: Ammonia; Cerebrovascular Circulation; Electroencephalography; Esophageal and Gastric Varices; Heart

1989
Propranolol and cirrhosis.
    Lancet (London, England), 1985, Jul-20, Volume: 2, Issue:8447

    Topics: Esophageal and Gastric Varices; Humans; Liver Cirrhosis; Propranolol

1985
Preventing hemorrhage from esophageal varices.
    The New England journal of medicine, 1987, Oct-01, Volume: 317, Issue:14

    Topics: Adrenergic beta-Antagonists; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Li

1987
Endoscopic, portographic, and hemodynamic evaluation of prolonged propranolol administration in pigs with experimental portal hypertension and esophageal varices.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:2

    Topics: Animals; Esophageal and Gastric Varices; Esophagoscopy; Hemodynamics; Hypertension, Portal; Liver; M

1989
[Prevention of hemorrhagic recurrence in Child's group A cirrhotic patients].
    Presse medicale (Paris, France : 1983), 1987, Sep-19, Volume: 16, Issue:30

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Portacaval Shu

1987
[Prevention of hemorrhagic recurrence in cirrhotic patients. Is sclerotherapy better than propranolol?].
    Presse medicale (Paris, France : 1983), 1988, Apr-09, Volume: 17, Issue:13

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirrhosis; Male;

1988
Propranolol and hemorrhage from esophageal varices.
    The New England journal of medicine, 1988, Apr-14, Volume: 318, Issue:15

    Topics: Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Propranolol

1988
Persistent hemorrhagic gastritis in a patient with portal hypertension and esophagogastric varices: the role of portal decompressive surgery.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:7

    Topics: Aged; Esophageal and Gastric Varices; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Hypert

1988
Bleeding colonic varices controlled by propranolol.
    Scottish medical journal, 1988, Volume: 33, Issue:6

    Topics: Colonic Diseases; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Cirrhos

1988
Esophageal variceal sclerotherapy: role for prophylaxis? Prophylactic sclerotherapy: an optimist.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:9

    Topics: Esophageal and Gastric Varices; Esophagoscopy; Humans; Liver Cirrhosis; Propranolol; Random Allocati

1988
Does propranolol precipitate hepatic encephalopathy?
    Journal of clinical gastroenterology, 1986, Volume: 8, Issue:1

    Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans;

1986
[Prevention of recurrent hemorrhage due to portal hypertension].
    Schweizerische medizinische Wochenschrift, 1986, Apr-26, Volume: 116, Issue:17

    Topics: Double-Blind Method; Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Hum

1986
Reversal of adrenaline-induced increase in azygos blood flow in patients with cirrhosis receiving propranolol.
    Journal of hepatology, 1987, Volume: 4, Issue:1

    Topics: Adult; Azygos Vein; Drug Interactions; Epinephrine; Esophageal and Gastric Varices; Female; Gastroin

1987
Emergency portacaval shunt for variceal hemorrhage. A prospective study.
    Annals of surgery, 1987, Volume: 206, Issue:1

    Topics: Emergencies; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Middle Aged; Porta

1987
Comparative study between propranolol and sclerotherapy in prophylactic treatment of oesophageal varices and prevention of recurrent bleeding attacks.
    Journal of the Egyptian Society of Parasitology, 1987, Volume: 17, Issue:2

    Topics: Adult; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Propr

1987
Management of bleeding oesophageal varices.
    British journal of hospital medicine, 1986, Volume: 35, Issue:2

    Topics: Esophageal and Gastric Varices; Esophagoscopy; Gastrointestinal Hemorrhage; Hemostatic Techniques; H

1986
[Portal hypertension in children. Therapeutic approach in cases of failure of a portosystemic shunt].
    Chirurgie pediatrique, 1986, Volume: 27, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cholestasis, Extrahepatic; Cholestasis, Intrahepatic; Esophagea

1986
[Indications for surgery in portal hypertension from the internist's viewpoint].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1985, Volume: 56, Issue:7

    Topics: Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal;

1985
Superior portosystemic collateral circulation estimated by azygos blood flow in patients with cirrhosis. Lack of correlation with oesophageal varices and gastrointestinal bleeding. Effect of propranolol.
    Journal of hepatology, 1985, Volume: 1, Issue:1

    Topics: Azygos Vein; Collateral Circulation; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hu

1985
[Propranolol and hemorrhage in cirrhosis].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:10

    Topics: Adult; Aged; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Liver Cirr

1985
[Propranolol prevention of hemorrhagic recurrence caused by rupture of esophageal varices: worsened prognosis in ascites and jaundice].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:11

    Topics: Ascites; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Jaundice; Live

1985
Effects of propranolol on portal hemodynamics in patients with chronic liver disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:2

    Topics: Adult; Aged; Esophageal and Gastric Varices; Female; Hemodynamics; Humans; Hypertension, Portal; Mal

1985
[Effective oral doses of propranolol, and endoscopic findings on the effects of propranolol on esophageal varices].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1985, Volume: 82, Issue:4

    Topics: Administration, Oral; Aged; Esophageal and Gastric Varices; Esophagoscopy; Female; Humans; Male; Mid

1985
[The effect of propranolol on portal hypertension in patients with varices after esophageal transection].
    Nihon Geka Gakkai zasshi, 1985, Volume: 86, Issue:8

    Topics: Esophageal and Gastric Varices; Esophagus; Hemodynamics; Humans; Hypertension, Portal; Postoperative

1985
[Nonsurgical therapy of esophageal varices by long-term propranolol administration].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1985, Volume: 82, Issue:9

    Topics: Aged; Esophageal and Gastric Varices; Female; Humans; Male; Middle Aged; Propranolol

1985
[Angiographic diagnosis and therapy of acute gastrointestinal hemorrhage].
    Medizinische Klinik, 1972, Apr-07, Volume: 67, Issue:14

    Topics: Aged; Angiography; Epinephrine; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage;

1972
Selective arterial infusions of vasoconstrictors in acute gastrointestinal bleeding.
    Radiology, 1971, Volume: 99, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Angiography; Arteriosclerosis; Celiac Artery; Crohn Disease;

1971