propranolol has been researched along with Erectile Dysfunction in 22 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Erectile Dysfunction: The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Participants in the Medical Research Council treatment trial for mild hypertension are randomly allocated to one of four treatment groups: bendrofluazide, propranolol, or a placebo for either of these drugs." | 9.05 | Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension. ( , 1981) |
| "This study aimed to investigate the role of insulin-like growth factor-binding protein-3 (IGFBP-3) in erectile dysfunction (ED) in two-kidney one-clip (2K-1C) hypertensive rats treated with the β-blocking agent propranolol." | 7.77 | Increased expression of insulin-like growth factor-binding protein-3 is implicated in erectile dysfunction in two-kidney one-clip hypertensive rats after propranolol treatment. ( Cao, H; Chen, D; Liu, QL; Peng, M; Wan, SP; Wang, XH; Wang, YZ; Yang, ZH; Zhou, HH; Zhou, ZY, 2011) |
| "Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases)." | 7.66 | Plasma sex hormone concentrations in men with hypertension treated with methyldopa and/or propranolol. ( Crisp, AJ; Hoffbrand, BI; Jacobs, HS; Maguire, A; Taylor, RG, 1981) |
| " Clinically, propranolol, an agent of this group, has been investigated in the treatment of various clinical disorders including schizophrenia, other psychoses, anxiety disorders, and stress reactions." | 6.15 | Propranolol in psychiatry. Therapeutic uses and side effects. ( Ananth, J; Lin, KM, 1986) |
| "Participants in the Medical Research Council treatment trial for mild hypertension are randomly allocated to one of four treatment groups: bendrofluazide, propranolol, or a placebo for either of these drugs." | 5.05 | Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension. ( , 1981) |
| "This study aimed to investigate the role of insulin-like growth factor-binding protein-3 (IGFBP-3) in erectile dysfunction (ED) in two-kidney one-clip (2K-1C) hypertensive rats treated with the β-blocking agent propranolol." | 3.77 | Increased expression of insulin-like growth factor-binding protein-3 is implicated in erectile dysfunction in two-kidney one-clip hypertensive rats after propranolol treatment. ( Cao, H; Chen, D; Liu, QL; Peng, M; Wan, SP; Wang, XH; Wang, YZ; Yang, ZH; Zhou, HH; Zhou, ZY, 2011) |
| "Serum concentrations of LH, FSH, testosterone and prolactin were measured in patients with hypertension treated with propranolol (34 cases), methyldopa (13 cases), and methyldopa + propranolol (11 cases)." | 3.66 | Plasma sex hormone concentrations in men with hypertension treated with methyldopa and/or propranolol. ( Crisp, AJ; Hoffbrand, BI; Jacobs, HS; Maguire, A; Taylor, RG, 1981) |
| "Four patients complaining of erectile dysfunction and using tobacco or propranolol were examined with penile blood pressure measurements and Doppler recordings, calculating the penile acceleration ratio (PAR)." | 3.66 | Impotence, smoking, and beta-blocking drugs. ( Forsberg, L; Gustavii, B; Höjerback, T; Olsson, AM, 1979) |
| " The bioavailability of IGF-1 at both mRNA and protein levels were measured by quantitative real-time PCR and Western blot respectively." | 1.43 | Decrease of the insulin-like growth factor-1 bioavailability in spontaneously hypertensive rats with erectile dysfunction. ( Cheng, SP; Huang, H; Huang, JB; Liu, RH; Mao, FJ; Pan, H; Sun, YL; Xiao, S; Zhong, GJ; Zhou, ZY, 2016) |
| "Three different regimens of drug treatment for hypertension were compared with regard to the development of undesirable side-effects in a group of 53 patients attending a hypertension clinic." | 1.26 | Some side-effects of alpha-methyldopa. ( Pillay, VK, 1976) |
| "Diarrhoea, impotence, failure of ejaculation, blurred vision, depression, and the symptoms of postural hypotension were not related to methyldopa therapy." | 1.25 | Side effects of hypotensive agents evaluated by a self-administered questionnaire. ( Bulpitt, CJ; Dollery, CT, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (81.82) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, ZY | 2 |
| Cheng, SP | 1 |
| Huang, H | 1 |
| Sun, YL | 1 |
| Xiao, S | 1 |
| Liu, RH | 1 |
| Mao, FJ | 1 |
| Zhong, GJ | 1 |
| Huang, JB | 1 |
| Pan, H | 1 |
| Yang, ZH | 1 |
| Wang, XH | 1 |
| Cao, H | 1 |
| Chen, D | 1 |
| Wang, YZ | 1 |
| Zhou, HH | 1 |
| Peng, M | 1 |
| Liu, QL | 1 |
| Wan, SP | 1 |
| Carani, C | 1 |
| Isidori, AM | 1 |
| Granata, A | 1 |
| Carosa, E | 1 |
| Maggi, M | 1 |
| Lenzi, A | 1 |
| Jannini, EA | 1 |
| Deshpande, VY | 1 |
| Mendulkar, KN | 1 |
| Moghe, PJ | 1 |
| Brahmapurikar, MT | 1 |
| Sadre, NL | 1 |
| Beeley, L | 1 |
| Taylor, RG | 1 |
| Crisp, AJ | 1 |
| Hoffbrand, BI | 1 |
| Maguire, A | 1 |
| Jacobs, HS | 1 |
| Campbell, IW | 1 |
| Ewing, DJ | 1 |
| Clarke, BF | 1 |
| Frances, A | 1 |
| Kaplan, HS | 1 |
| Moss, HB | 1 |
| Procci, WR | 1 |
| Stoeckly, VL | 1 |
| Srilatha, B | 1 |
| Adaikan, PG | 1 |
| Arulkumaran, S | 1 |
| Ng, SC | 1 |
| Forsberg, L | 1 |
| Gustavii, B | 1 |
| Höjerback, T | 1 |
| Olsson, AM | 1 |
| Bathen, J | 1 |
| Warren, SC | 1 |
| Warren, SG | 1 |
| Knarr, JW | 1 |
| Miller, RA | 1 |
| Pillay, VK | 1 |
| Ananth, J | 1 |
| Lin, KM | 1 |
| McNay, JL | 1 |
| Newman, RJ | 1 |
| Salerno, HR | 1 |
| Bulpitt, CJ | 1 |
| Dollery, CT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Combined Antihypertensive Therapy on Blood Pressure and Sexual Function in Patients With Essential Hypertension[NCT01238705] | Phase 4 | 280 participants (Anticipated) | Interventional | 2008-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Erectile Dysfunction
| Article | Year |
|---|---|
Drug-induced sexual dysfunction and infertility.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzothiadiazines; Child; Cimetidine; | 1984 |
Propranolol in psychiatry. Therapeutic uses and side effects.
Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top | 1986 |
2 trials available for propranolol and Erectile Dysfunction
| Article | Year |
|---|---|
Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Erectile Dysfunction; Fem | 1981 |
Propranolol in psychiatry. Therapeutic uses and side effects.
Topics: Adolescent; Adult; Anxiety Disorders; Central Nervous System Diseases; Child; Clinical Trials as Top | 1986 |
19 other studies available for propranolol and Erectile Dysfunction
| Article | Year |
|---|---|
Decrease of the insulin-like growth factor-1 bioavailability in spontaneously hypertensive rats with erectile dysfunction.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Cyclic GMP; Disease Models, Animal; Enzyme-Link | 2016 |
Increased expression of insulin-like growth factor-binding protein-3 is implicated in erectile dysfunction in two-kidney one-clip hypertensive rats after propranolol treatment.
Topics: Animals; Antihypertensive Agents; Base Sequence; Blotting, Western; DNA Primers; Enzyme-Linked Immun | 2011 |
Multicenter study on the prevalence of sexual symptoms in male hypo- and hyperthyroid patients.
Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Benzodiazepines; Drug Therapy, Combination; Ejacula | 2005 |
Effect of different beta-adrenoceptor antagonists on reproduction in male mice.
Topics: Adrenergic beta-Antagonists; Animals; Erectile Dysfunction; Female; Humans; Infertility, Male; Libid | 1981 |
Plasma sex hormone concentrations in men with hypertension treated with methyldopa and/or propranolol.
Topics: Adult; Aged; Erectile Dysfunction; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; H | 1981 |
Tests of cardiovascular reflex function in diabetic autonomic neuropathy.
Topics: Adolescent; Adult; Age Factors; Aged; Atropine; Autonomic Nervous System; Blood Pressure; Cardiovasc | 1980 |
Patient on hypertensive drug has increasing erectile problems.
Topics: Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Propranolol | 1982 |
Sexual dysfunction associated with oral antihypertensive medication: a critical survey of the literature.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Erectile Dysfunction; Guanethidine; Humans; Hypertens | 1982 |
Propranolol-induced impotency--correction of an error.
Topics: Erectile Dysfunction; Humans; Male; Propranolol | 1981 |
Sexual dysfunction related to antihypertensive agents: results from the animal model.
Topics: Animals; Antihypertensive Agents; Captopril; Clonidine; Copulation; Electric Stimulation; Erectile D | 1999 |
Impotence, smoking, and beta-blocking drugs.
Topics: Adult; Erectile Dysfunction; Humans; Male; Middle Aged; Propranolol; Smoking | 1979 |
Propranolol erectile dysfunction relieved.
Topics: Adult; Erectile Dysfunction; Humans; Male; Propranolol | 1978 |
Propranolol and sexual impotence.
Topics: Erectile Dysfunction; Humans; Male; Propranolol | 1977 |
Letter: Impotence from propranolol?
Topics: Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Propranolol | 1976 |
Propranolol and impotence.
Topics: Erectile Dysfunction; Humans; Male; Middle Aged; Propranolol | 1976 |
Some side-effects of alpha-methyldopa.
Topics: Adult; Aged; Chlorthalidone; Drug Therapy, Combination; Erectile Dysfunction; Humans; Hydralazine; H | 1976 |
Adrenolytic and vasodilator therapy.
Topics: Adrenergic beta-Antagonists; Benzyl Compounds; Blood Circulation; Cardiac Output; Clonidine; Diazoxi | 1974 |
Letter: Sexual dysfunction due to methyldopa.
Topics: Adult; Ejaculation; Erectile Dysfunction; Humans; Hydralazine; Libido; Male; Methyldopa; Middle Aged | 1974 |
Side effects of hypotensive agents evaluated by a self-administered questionnaire.
Topics: Antihypertensive Agents; Defecation; Diuretics; Ejaculation; Erectile Dysfunction; Female; Guanethid | 1973 |