Page last updated: 2024-11-03

propranolol and Endotoxemia

propranolol has been researched along with Endotoxemia in 6 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to investigate in vivo the effects of modulating the adenosine system on endotoxin-induced release of cytokines and changes in heart performance and neurohumoral status in early, profound endotoxemia in rats."3.71Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats. ( Carcillo, JA; Jackson, EK; Tofovic, SP; Zacharia, L, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arcaroli, J2
Yang, KY1
Yum, HK1
Kupfner, J1
Pitts, TM1
Park, JS1
Strassheim, D1
Abraham, E2
Gardiner, SM1
March, JE1
Kemp, PA1
Bennett, T1
Boost, KA1
Flondor, M1
Hofstetter, C1
Platacis, I1
Stegewerth, K1
Hoegl, S1
Nguyen, T1
Muhl, H1
Zwissler, B1
Szelényi, J1
Kiss, JP1
Puskás, E1
Selmeczy, Z1
Szelényi, M1
Vizi, ES1
Shenkar, R1
Tofovic, SP1
Zacharia, L1
Carcillo, JA1
Jackson, EK1

Other Studies

6 other studies available for propranolol and Endotoxemia

ArticleYear
Effects of catecholamines on kinase activation in lung neutrophils after hemorrhage or endotoxemia.
    Journal of leukocyte biology, 2002, Volume: 72, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A

2002
Involvement of CB1-receptors and beta-adrenoceptors in the regional hemodynamic responses to lipopolysaccharide infusion in conscious rats.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Consciousness; Disease Models, Animal; Drug In

2005
The beta-adrenoceptor antagonist propranolol counteracts anti-inflammatory effects of isoflurane in rat endotoxemia.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:7

    Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents; Blood Press

2007
Opposite role of alpha2- and beta-adrenoceptors in the modulation of interleukin-10 production in endotoxaemic mice.
    Neuroreport, 2000, Nov-09, Volume: 11, Issue:16

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Endotoxemia; Enzyme-Linked Immunos

2000
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animal Feed; Animals; Cyclic AMP Response

2001
Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats.
    Shock (Augusta, Ga.), 2001, Volume: 16, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blood Pressure; Ca

2001