propranolol has been researched along with Elevated Cholesterol in 16 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 59 patients with mild or moderate essential hypertension effects of propranolol and hydrochlorothiazide on serum lipids, fibrynogen, glucose and uric acid concentrations as well as serum euglobulins fibrynolysis time were studied." | 7.67 | [Effect of long-term treatment with propranolol or hydrochlorothiazide on biochemical risk factors of coronary disease in patients with hypertension]. ( Karolko, B; Kawecka, M; Lukasik, S; Moszczyńska, J; Witkowska, M, 1989) |
| "In 59 patients with mild or moderate essential hypertension effects of propranolol and hydrochlorothiazide on serum lipids, fibrynogen, glucose and uric acid concentrations as well as serum euglobulins fibrynolysis time were studied." | 3.67 | [Effect of long-term treatment with propranolol or hydrochlorothiazide on biochemical risk factors of coronary disease in patients with hypertension]. ( Karolko, B; Kawecka, M; Lukasik, S; Moszczyńska, J; Witkowska, M, 1989) |
| " This epinephrine-induced hypercholesterolemia was enhanced by phentolamine (25 mg/kg) and inhibited by propranolol (25 mg/kg)." | 3.66 | Effects of epinephrine on plasma cholesterol levels in rats. ( Kunihara, M; Oshima, T, 1983) |
| " In the light of the results obtained, the following conclusions were drawn: 1) hyperlipidemia affects pharmacodynamic properties of lipophilic propranolol and hydrophilic atenolol, 2) a modification of the drug dosage in hyperlipidemia is warranted." | 2.71 | [Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol]. ( Droździk, M; Gawrońska-Szklarz, B; Sterna, R; Sulzyc-Bielicka, V; Telatyńska-Smieszek, B; Wójcicki, J, 2004) |
| "Propranolol was given orally as a single dose 80 mg." | 2.68 | [The effect of hypolipemic treatment on the pharmacokinetics of propranolol]. ( Sterna, R, 1997) |
| " Systemic exposure is limited because of extensive sequestration by the liver and/or first-pass metabolism, a plasma half-life of approximately 30 min, no circulating active metabolites, and no accumulation of drug during chronic dosing." | 2.67 | Pharmacokinetics of fluvastatin and specific drug interactions. ( Hwang, DS; Jokubaitis, LA; Robinson, WT; Smith, HT; Troendle, AJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Telatyńska-Smieszek, B | 1 |
| Wójcicki, J | 1 |
| Droździk, M | 1 |
| Gawrońska-Szklarz, B | 1 |
| Sulzyc-Bielicka, V | 1 |
| Sterna, R | 2 |
| Kunihara, M | 1 |
| Oshima, T | 1 |
| Poliakova, ED | 1 |
| Ivanova, TN | 1 |
| Nikulina, SE | 1 |
| Metel'skaia, VA | 1 |
| Olfer'ev, AM | 1 |
| Shcherbakova, IA | 1 |
| Akhmedzhanov, NM | 1 |
| Perova, NV | 1 |
| Horwitz, RI | 1 |
| Horwitz, SM | 1 |
| Smith, HT | 1 |
| Jokubaitis, LA | 1 |
| Troendle, AJ | 1 |
| Hwang, DS | 1 |
| Robinson, WT | 1 |
| Brennan, FX | 1 |
| Cobb, CL | 1 |
| Silbert, LH | 1 |
| Watkins, LR | 1 |
| Maier, SF | 1 |
| Makaritsis, KP | 1 |
| Gavras, H | 1 |
| Du, Y | 1 |
| Chobanian, AV | 1 |
| Brecher, P | 1 |
| Fogari, R | 1 |
| Zoppi, A | 1 |
| Corradi, L | 1 |
| Preti, P | 1 |
| Mugellini, A | 1 |
| Lusardi, P | 1 |
| Witkowska, M | 1 |
| Lukasik, S | 1 |
| Kawecka, M | 1 |
| Moszczyńska, J | 1 |
| Karolko, B | 1 |
| Leon, AS | 1 |
| Hunninghake, DB | 1 |
| Belcher, J | 1 |
| Stoulil, J | 1 |
| Wright, CE | 1 |
| Angus, JA | 1 |
| Brook, JG | 1 |
| Marmur, A | 1 |
| Berkovitch, Y | 1 |
| Aviram, M | 1 |
| Krikler, DM | 1 |
| Lefevre, D | 1 |
| Lewis, B | 1 |
| Perrier, H | 1 |
| Perrier, C | 1 |
| Gudefin, Y | 1 |
| Gras, J | 1 |
| Tulloch, BR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development and Evaluation of a Therapeutic Education Intervention Focused on the Accession of Patients Treated With Hormonal Therapy in the Management of Breast Cancer: PEPs Hormonotherapy[NCT02300675] | 352 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Elevated Cholesterol
| Article | Year |
|---|---|
Adherence to treatment and health outcomes.
Topics: Clofibrate; Double-Blind Method; Evaluation Studies as Topic; Humans; Hypercholesterolemia; Male; My | 1993 |
Lipid changes in thyroid disease: the effect of thyroxine and analogues.
Topics: Animals; Cholesterol; Humans; Hypercholesterolemia; Hyperthyroidism; In Vitro Techniques; Lipid Meta | 1974 |
5 trials available for propranolol and Elevated Cholesterol
| Article | Year |
|---|---|
[Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Area Under Curve; Atenolol; Blood Pressure; Chrom | 2004 |
Pharmacokinetics of fluvastatin and specific drug interactions.
Topics: Adolescent; Adult; Aged; Aging; Biological Availability; Cholestyramine Resin; Diet; Digoxin; Dose-R | 1993 |
[The effect of hypolipemic treatment on the pharmacokinetics of propranolol].
Topics: Administration, Oral; Anticholesteremic Agents; Bezafibrate; Chromatography, High Pressure Liquid; D | 1997 |
Beta-blocker effects on plasma lipids during prolonged treatment of hypertensive patients with hypercholesterolemia.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Atenolol; Bisopr | 1999 |
Comparative effects of prazosin and propranolol on blood lipid profiles in hypertensive, hypercholesterolemic patients. Preliminary results.
Topics: Adult; Aged; Apoproteins; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholester | 1989 |
9 other studies available for propranolol and Elevated Cholesterol
| Article | Year |
|---|---|
Effects of epinephrine on plasma cholesterol levels in rats.
Topics: Adrenal Glands; Animals; Cholesterol; Corticosterone; Epinephrine; Hypercholesterolemia; Male; Phent | 1983 |
[Changes in the rate of cholesterol synthesis in lymphocytes, and blood lipid and lipoprotein levels in patients with ischemic heart disease and hypercholesterolemia during treatment with lovastatin and obsidan].
Topics: Adult; Cholesterol; Drug Interactions; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipi | 1994 |
Peripheral beta-adrenoreceptors and stress-induced hypercholesterolemia in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Butoxamine; Electroshock; Fatty Acids, Nonesterified | 1996 |
Alpha1-adrenergic plus angiotensin receptor blockade reduces atherosclerosis in apolipoprotein E-deficient mice.
Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Ap | 1998 |
[Effect of long-term treatment with propranolol or hydrochlorothiazide on biochemical risk factors of coronary disease in patients with hypertension].
Topics: Adult; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Hype | 1989 |
Effects of hypertension and hypercholesterolemia on vasodilatation in the rabbit.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Body Weight; Female; Guanethidine; Heart Ra | 1986 |
Platelet adhesion in hyperlipidemic and hypertensive patients.
Topics: Adult; Arteriosclerosis; Atenolol; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinem | 1985 |
Dextrothyroxine with propranolol in treatment of hypercholesterolaemia.
Topics: Adult; Body Weight; Cholesterol; Dextrothyroxine; Female; Humans; Hypercholesterolemia; Male; Middle | 1971 |
Adrenaline-induced hypercholesterolemia in the rainbow trout (Salmo gairdnerii Richardson): a separate study in male and female trout and the effect of adrenergic blocking agents.
Topics: Animals; Blood Proteins; Epinephrine; Fatty Acids, Nonesterified; Female; Hypercholesterolemia; Male | 1972 |