propranolol has been researched along with Donohue Syndrome in 2 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Donohue Syndrome: Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic FACIES; HIRSUTISM; VIRILIZATION; multiple endocrine abnormalities, and early death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donohue syndrome (leprechaunism; OMIM *246200) is a rare, recessively inherited disorder of extreme insulin resistance due to mutations in the insulin receptor gene (INSR) causing either defects in insulin binding or receptor autophosphorylation and tyrosine kinase activity." | 1.39 | Severe progressive obstructive cardiomyopathy and renal tubular dysfunction in Donohue syndrome with decreased insulin receptor autophosphorylation due to a novel INSR mutation. ( Battelino, T; Bratanič, N; Bratina, N; Hovnik, T; Kovač, J; Paro, D; Podkrajšek, KT; Podnar, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, Y | 1 |
| Watanabe, T | 1 |
| Hovnik, T | 1 |
| Bratanič, N | 1 |
| Podkrajšek, KT | 1 |
| Kovač, J | 1 |
| Paro, D | 1 |
| Podnar, T | 1 |
| Bratina, N | 1 |
| Battelino, T | 1 |
2 other studies available for propranolol and Donohue Syndrome
| Article | Year |
|---|---|
Renal tubular dysfunction in patients with molecular defects of the insulin receptor gene.
Topics: Cardiomyopathy, Hypertrophic; Donohue Syndrome; Humans; Insulin Resistance; Insulin-Like Growth Fact | 2014 |
Severe progressive obstructive cardiomyopathy and renal tubular dysfunction in Donohue syndrome with decreased insulin receptor autophosphorylation due to a novel INSR mutation.
Topics: Cardiomyopathy, Hypertrophic; Donohue Syndrome; Fatal Outcome; Growth Disorders; Humans; Insulin Res | 2013 |