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propranolol and Disease

propranolol has been researched along with Disease in 4 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Disease: A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Research Excerpts

ExcerptRelevanceReference
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."7.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)
"To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers."3.66Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piafsky, KM1
Borgá, O1
Odar-Cederlöf, I1
Johansson, C1
Sjöqvist, F1
Jusko, WJ1
Gretch, M1
McNamara, PJ1
Jewell, RC1
Gillespie, MN1
Azarnoff, DL1

Reviews

2 reviews available for propranolol and Disease

ArticleYear
Plasma and tissue protein binding of drugs in pharmacokinetics.
    Drug metabolism reviews, 1976, Volume: 5, Issue:1

    Topics: Adrenal Cortex Hormones; Age Factors; Aging; Albumins; Animals; Anti-Bacterial Agents; Antibodies; A

1976
The interaction of alpha-1-acid glycoprotein with endogenous autocoids, in particular, platelet activating factor (PAF).
    Progress in clinical and biological research, 1989, Volume: 300

    Topics: Biological Transport; Blood Proteins; Cations; Disease; Humans; Orosomucoid; Pharmacokinetics; Plate

1989

Other Studies

2 other studies available for propranolol and Disease

ArticleYear
Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein.
    The New England journal of medicine, 1978, Dec-28, Volume: 299, Issue:26

    Topics: Adult; Aged; alpha-Macroglobulins; Arthritis; Chlorpromazine; Crohn Disease; Disease; Female; Humans

1978
Application of blood level data to clinical trials.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:1

    Topics: Alkylating Agents; Biopharmaceutics; Disease; Dose-Response Relationship, Drug; Drug Interactions; D

1974